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Total Results: 1,445 records

Showing results for "large".

161. DEcIDE 33: Summary Variables in Observational Resesarch: Propensity Scores and Disease Risk Scores (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/observational-research-scores_research.pdf
     May 01, 2012 - Both provide a means of accounting for a large number of measured covariates through a single computed … This large sample size requirement means that answering the question through a randomized controlled … trial would be very expensive and need to include a very large patient population followed for some … When there are a large number of covariates that influence disease (or other outcome) risk, in this … Estimating causal effects from large data sets using propensity scores.

162. Disposition of Comments for Treatments for Fibromyalgia in Adult Subgroups (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/fibromyalgia_disposition-comments.pdf
     January 26, 2015 - We realize there is limited space in such a large topic, however in each area it would improve the report … available epidemiological data whether this is relatively representative of the FMS population at large … quantitative analysis with pooling of data was not possible due to the relatively few studies and large … The authors just didn’t have a large enough literature available to address all of the questions that … 11 and Discussion pg. 40: A meta-analysis was not possible due to relatively few studies and the large

163. Disposition of Comments Report for Antiplatelet and Anticoagulant Treatments for Unstable Angina/Non-ST Elevation Myocardial Infarction (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/angina-heart-attack-treatments_disposition-comments.pdf
     January 01, 2014 - This is already a very large report, and delving further into the background for these drugs is out … Recommend deleting observational data as they add little to a field with so many large RCTs. … This issue is important because the Boersma meta-analysis suggests that the large majority of the MI … As a result, there are a large number of major findings. … TEP Member 2 General This is an extremely large and comprehensive effort, which generally is of very

164. Arcia-notes-Teresa (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/arcia-presentation.pdf
     May 29, 2025 - Infrastructure for   Community-­‐Centered Comparative   Effectiveness Research. 4 WICER was a large … I would   like to conclude by mentioning again  that technology is what makes some of this large

165. Asthma-Treatment Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/asthma-treatment_executive.pdf
     May 01, 2011 - For the question of harms, we would also have included large observational studies as well as trials … some other flaw judged to be so serious as to cast doubt on the validity of the results, such as large … Another trial with a very intensive intervention reported a very large effect size at 2- and 4-week … The best quality trial of yoga conducted in India showing large benefits of treatment reported that … There was only one trial that could be considered large, and more than half of the trials included

166. Evidence Summary_Comparative Effectiveness Review No. 248: Prehabilitation and Rehabilitation for Major Joint Replacement (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/joint-replacement-evidence%20-summary.pdf
     November 01, 2021 - Limitations Although we found a large body of mostly RCT evidence, the evidence was ultimately sparse

167. Comparative Effectiveness of Adjunctive Devices to Remove Thrombi or Protect Against Distal Embolization in Patients with Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention of Native Vessels (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/acs-pci-adjunctive-devices_disposition-comments.pdf
     March 01, 2012 - Secondly, the large majority of data were within the STEMI population and very little if any data were … Aspiration in STEMI population When a large preponderance of the evidence was from “good” quality … evidence from good quality trials on longest followup should have been graded for SOE instead When a large

168. Machine-Learning-Tools-Appendix-C (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/machine-learning-tools-appendix-c.xlsx
     January 01, 2024 - Literature Search Sandbox: a Large Language Model that generates search queries for systematic reviews … Literature Search Sandbox: a Large Language Model that generates search queries for systematic reviews … Development of meta-prompts for Large Language Models to screen titles and abstracts for diagnostic test … Sensitivity, specificity and avoidable workload of using a large language models for title and abstract … Automated Paper Screening for Clinical Reviews Using Large Language Models: Data Analysis Study 2024

169. Version 2_Risk of Reinfection From SARS-CoV-2 -- An Update of an Antibody Response Following SARS-CoV-2 Infection and Implications for Immunity: A Living Rapid Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/version-2-risk-of-reinfection-from-SARSCoV2_0.pdf
     December 31, 2022 - (I2 = ~85%), but this value should be interpreted in the context of high precision resulting from large … In the other relatively large series, a study from Austria, five cases were described as moderate and … 37-39 Because prior infection and vaccination both provide strong protection against infection, large … PCR test at least 90 13 days after the initial positive PCR test.14 A large … The evidence for an overall effect is consistent, and the effect sizes are too large to be accounted

170. S158 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/s158.pdf
     October 01, 2007 - Avorn, MD,* and Sebastian Schneeweiss, MD*� Background: Nonexperimental studies of drug effects in large … Random assignment of a large number of subjects into treatment groups usually leads to a good balance … chronic diseases.8 The problem can be more pronounced in pharmacoepi- demiologic studies based on large … and diseases, because they allow timely assessment of infrequently used drugs and rare outcomes in large … Controlling confounding when studying large pharmacoepidemiologic databases: a case study of the two-stage

171. Module IV- Skills for Successful Engagement (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/module-iv-skills-for-successful-engagement.pdf
     May 29, 2025 - similar to those typically used by investigators to complete research processes (such as synthesizing large … of stakeholders with achieving results § Active listening § Flexibility § Ability to synthesize large … This is similar to sorting through large amounts of written data to find appropriate, reliable, and

172. Effective Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-radiation_technical-brief.pdf
     November 01, 2009 - Large particle beam facilities that are being built in the US ..................................... … tissues.12,13 However, stereotactic radiosurgery with photons is typically not used to irradiate large … Gantries are large devices that can rotate 360 degrees (full circle) to deliver the particle beam at … Large particle beam facilities that are being built in the US Institute Now in construction Parti … Few centers worldwide have the large and very expensive facilities to provide this treatment.

173. Topic Brief: Antenatal Care (pdf file)
     effectivehealthcare.ahrq.gov/system/files/docs/topic-brief-antenatal-care.pdf
     April 01, 2021 - Because a large number of articles were identified (n=1675), we reviewed a random sample of 200 titles … Represents a significant disease burden; large proportion of the population Yes, in 2018 there were … Is of high public interest; affects health care decision making, outcomes, or costs for a large proportion

174. Topic 0533 Postpartum Hemorrhage NSD FINALsj (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0652-131114.pdf
     May 15, 2013 - (ACOG) and two systematic reviews from the Cochrane Collaboration on primary and secondary PPH, a large

175. White Paper_Supplementing Systematic Review Findings With Healthcare System Data: Pilot Projects From the Agency for Healthcare Research and Quality Evidence-based Practice Center Program (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/pilot-projects-supplementing-white-paper.pdf
     December 01, 2024 - studies excluded older adults with hip fractures.11, 12 The supplemental data analysis identified a large … systematic review topics suitable for supplemental analyses should include researchers familiar with large … Suitable topics for large database studies to augment reporting of harms include cases with dichotomous … small proportion of EPC evidence review topics would benefit from supplementary data analysis, unless large … evidence gap(s) identified in systematic reviews, investigators could consider leveraging existing large

176. Ptsd-Adult-Treatment Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-adult-treatment_executive.pdf
     April 01, 2013 - Effect sizes were generally large for psychological treatments, with moderate SOE supporting efficacy … benefits; wide range of effect sizes in the 2 trials reporting sufficient data, from medium to very large … A small effect size is d=0.20, medium effect size is d=0.50, and large effect size is d=0.80.c Baseline … Analyses were generally not powered to detect anything but large differences. … We set this criterion for two main reasons: (1) our topic refinement process found a large number of

177. Biomarkers for Assessing and Managing Iron Deficiency Anemia in Late-Stage Chronic Kidney Disease: Future Research Needs (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-kidney-disease-anemia_research.pdf
     January 01, 2013 - However, across studies, there are large variations in the definitions of these reference standards. … However, across studies, there are large variations in the definitions of these reference standards. … Resource Use, Size, and Duration Cohort studies often require large samples, so it may be necessary … Importance: • Represents a significant disease burden, large proportion or priority population. … • Is of high public interest; affects health care decision-making, outcomes, or costs for a large

178. GRADING THE STRENGTH OF A BODY OF EVIDENCE (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-grading-strength_methods.pdf
     July 01, 2009 - systems that are designed to be used directly by decisionmakers. 2 The EPC approach is based in large … Even if the study is a large multicenter trial (i.e., a mega-trial), findings from different centers … this Methods Guide (see Principles for Developing Guidance for Comparing Medical Interventions),3 a large … This additional domain should be considered if the effect size is particularly large. … Use one of two levels: • Strong: Large effect size that is unlikely to have occurred in the absence

179. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer_executive.pdf
     February 01, 2008 - Additional estimates for U.S. population-based AEs at 5 years following treatment were obtained from a large … pooling of results was difficult; when results were pooled, the geographic regions used were quite large … Estimates from large ongoing screening trials suggest that PSA increases the time of detection by 5-15 … High-quality, large prospective cohort studies or cancer registries that identify men at the time of … Physician specialty and Medium • Surveys and large national administrative databases indicate preferences

180. Multidisciplinary Postacute Rehabilitation for Moderate to Severe Traumatic Brain Injury in Adults Disposition of Comments (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/traumatic-brain-injury-rehabilitation_disposition-comments.pdf
     October 07, 2012 - Peer Reviewer #6 Results One can get lost in the the large amount of details and the way in which each … A large number of prior systematic reviews on TBI were cited by the authors in proportion to only the … The large number of systematic reviews with differing conclusions will only add to the confusion, not … While one would hope that these programs, in the aggregate, have an impact on extremely large scale … This creates large economic burdens, particularly when it is compounded with concomitant psychiatric