-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0261_07-16-2010.pdf
January 01, 2010 - For patients with chronic diseases where large numbers of physicians do not follow
Interventions to
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0024_06-09-2008.pdf
January 01, 2008 - While there appears
to be a large amount of comparative effectiveness research focused on schizophrenia
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0012_03-21-2008.pdf
January 01, 2008 - Both the AHRQ and the Cochrane review listed above concluded that further large randomized
controlled
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoporosis-bone-fracture_disposition-comments.pdf
March 01, 2012 - Chapell,
Richard
Structured
Abstract
To summarize a large and complex document in a single page … These large trials also did
not detect an increase of mild cardiac events with raloxifene. … Where are the very large MORE and
CORE trials? … More data are
needed on fracture prevention in this large patient population. … I did have two fairly large
concerns, though.
-
effectivehealthcare.ahrq.gov/sites/default/files/s131.pdf
October 01, 2007 - research,1 confounding bias is of particular concern in epidemi-
ologic studies of drug effects.2
Large … The large size of such databases, however, makes
it feasible to restrict on many criteria without reducing … Obviously, patients on therapy most likely have a
medical indication; by contrast a large proportion … When compared with results from large
population-based pharmacoepidemiologic studies, the ques-
tion … Estimating causal effects from large data sets using propen-
sity scores.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/phenylketonuria_executive.pdf
February 01, 2012 - In addition to a Phe-restricted diet and BH4, another
potential treatment for PKU is large neutral amino … Analytic framework for treatment questions
BH4 = sapropterin dihydrochloride; LNAAs = large neutral … Thus, while the strength of evidence is moderate
for a large positive effect of BH4 on reducing Phe … Large neutral amino
acids in the treatment of phenylketonuria (PKU). … The effects
of large neutral amino acid supplements in PKU: an MRS and
neuropsychological study.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/distributed-network-safety_research.pdf
July 01, 2009 - The Need for a Large, Distributed Research Network
As described above, AHRQ and others (e.g., the IOM … cohorts of patients for vaccine safety, is a large, expensive, and time-consuming
endeavor. … The Penn
database resources include: (1) Medicaid data from five large programs linked to Medicare … Although these DRN design approaches should
mitigate risks, if some large data owners do not accept … Third, requests or queries
run less efficiently on large centralized databases.
f.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-hospitalizations_research.pdf
October 01, 2008 - These resources are attractive because the information recorded represents large
populations in the … insufficient to address these safety concerns conclusively, thus
epidemiologic studies performed in large … definition for pneumonia, that definition as well as
other definitions for this study was based in large … and coding among patients with RA, is
unknown.15
Conclusion
The increasing availability of large
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/methods-guide-inclusion-nonrandomized-studies.pdf
September 01, 2022 - However, the reviewers included large NRSIs for assessment of rare serious adverse
events. … When the evidence matures to a stage where large seminal RCTs are available, NRSIs may
be excluded if … Because of large sample sizes, high precision of treatment effect sizes is often attained,
which may … Moreover, because of their generally large
sample sizes, effect size estimates from individual NRSIs … Large-scale
randomized evidence: large, simple trials
and overviews of trials.
-
effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/methods-guide-inclusion-nonrandomized-studies.pdf
September 01, 2022 - However, the reviewers included large NRSIs for assessment of rare serious adverse
events. … When the evidence matures to a stage where large seminal RCTs are available, NRSIs may
be excluded if … Because of large sample sizes, high precision of treatment effect sizes is often attained,
which may … Moreover, because of their generally large
sample sizes, effect size estimates from individual NRSIs … Large-scale
randomized evidence: large, simple trials
and overviews of trials.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/meditation_research-protocol.pdf
October 17, 2012 - Given the increasing use of meditation across a large number of conditions, examining the effects of … Furthermore, given the anticipated large number of trials that have
moved to a more rigorous design … movement-based programs require
their own nomination and evaluation in a separate systematic review given the large … They had serious errors in design, analysis, or reporting; large amounts of missing
information; or … difference in change graphs will be
used to determine the consistency of reported
effects.
2) For the large
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/gaps-pain-management.pdf
January 01, 2023 - There may be a large increased
risk of dizziness and sedation and a moderately
increased risk of nausea … improvement in pain severity, no effect on
overall function, an increased risk of sedation,
and large … • Extracted whole-plant products with higher THC
than CBD may be associated with large
increases … In general, evidence on
quality of life was limited and no treatment
achieved a large improvement in … Large increases in withdrawal due to
adverse events were seen with oxcarbazepine.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/trauma-interventions-maltreatment-child_disposition-comments.pdf
April 15, 2013 - We recognize this
limitation in large part reflects the
challenges of collecting accurate
Source: … We explicitly discuss the need for
high quality, large-scale, multisite
trials that can assess treatment … not offer any discussion of the
limitations of RCTs in that they are:
• Hard to do well
• Require large … A large body of literature has been
identified and the fraction of that literature meeting standards … Also, as noted previously, the
report now explicitly emphasizes
the need for high quality, large-
scale
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/thromboembolism-update-disposition.pdf
June 22, 2017 - Thank you
Peer
Reviewer #4
General
Comments
Overall, there are a large number of
studies, but … We have re-reviewed the very large
observational study from the UK with
over 100,000 study participants … Medtronic
(Michael
Tarnoff, MD,
FACS)
Methods Additionally, one large trial (Eisele et al.,
2007 … This large
randomized trial is considered Level I
evidence in support of mechanical
prophylaxis. … Limitations of the Evidence are clear
stating that despite the large number of
studies the researches
-
effectivehealthcare.ahrq.gov/sites/default/files/mcda_webinar_transcript2.pdf
August 27, 2012 - really
relevant to consider in the MCDA is the heterogeneity so if
we use MCDA approaches in the large … survey and we survey
among a large group of people there might be preference
heterogeneity within … MOHR: I guess, Maarten, I have a question, then, because
conjoint analysis does require a fairly large … number of topics or if
there is a relatively large number of criteria that
stakeholders employ. … On the other hand,
if you want to collect preferences over a large number of
people and a wide number
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0645-151012.pdf
August 05, 2015 - Therefore, a large body of recent literature exists.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0265_02-29-2008.pdf
January 01, 2008 - Is there a model that might be effective for multi-modal treatment that might work in
a large system
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoarthritis-knee-future_research.pdf
February 01, 2013 - Prospective cohort studies with large samples may
ES-7
be preferred to small RCTs, yet no … Large
sample sizes and the identification, measurement, and appropriate adjustment for confounding … A large sample will be required and follow-up should extend
beyond treatment duration. … A large sample will be
required and follow-up should extend beyond
treatment duration. … A large sample will be
required and follow-up should extend beyond
treatment duration.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/autism-adolescents_research-protocol.pdf
March 29, 2011 - billion for an entire birth cohort of individuals with autism.14 A study of health care utilization
in a large … balance, allowing us to review
and comment on adequate literature for the review but with studies large … portion of the ASD literature, as
noted in a previous AHRQ review of therapies for ASD in children.18 Large … Pre-specifying each measure to extract is not feasible given
the large number of assessment tools/measures … of health care utilization and costs of children with and
without autism spectrum disorders in a large
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/epc-making-sure-evidence-understood.pdf
July 01, 2020 - and
public and private insurers
Coverage by public or private purchasers of health care plays a large … These methods
are designed to reduce bias and allow researchers to synthesize large amounts of
information