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Total Results: 1,445 records

Showing results for "large".

101. Disposition of Comments_Technical Brief No. 40: Interventions To Decrease Hospital Length of Stay (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/hospital-length-of-stay-disposition-comments_0.pdf
     September 20, 2021 - diverse and representative they are, it would strengthen and validate their insights (i.e, not a large … The dearth of data regarding patients with social and economic barriers is a large issue. … This is a large issue. … LOS is a hospital-centric measure and may not have as large of a role in a total cost of care/population

102. Disposition of Comments Report for The Patient-Centered Medical Home (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/patient-centered-medical-home_disposition-comments.pdf
     July 03, 2012 - The authors are correct in their emphasis on studies that include large proportions of patients in a … With no incentives for large-scale Medical Home change in either the existing health care delivery … In fact, these issues are central to well-child care and also constitute a large proportion of other … The lack of evidence from large-scale studies is largely due to a lack of funding for these studies, … and funding for large-scale practice change currently does not exist.

103. Future Research Needs for Diagnosis of Obstructive Sleep Apnea (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/sleep-apnea-diagnosis-future_research.pdf
     February 01, 2012 - These could result in the use of large resources in terms of cost, time and effort, and the decision … In summary, the online Web site discussion of numerous topics by a large stakeholder panel was only … Ability To Recruit The sampling population is large, as there are thousands of patients who undergo … This approach would be able to provide a large sample of patients from diverse geographic locations, … Represents a significant disease burden; large proportion or priority population 2b.

104. Prioritization Criteria Methodology for Future Research Needs Proposals Within the Effective Health Care Program (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/future-research-prioritization-methods_research.pdf
     January 01, 2013 - changing determinants and pattern of diseases or conditions and their effect on the population at large … Importance 1 Represents a significant disease burden affecting a large proportion of the population … . 2 Is of high public interest, affecting health care decision making, outcomes, or costs for a large … Represents a significant disease burden affecting a large proportion of the population or a priority … Is of high public interest, affecting health care decision making, outcomes, or costs for a large proportion

105. Research Protocol for Interventions for Substance Use Disorders in Adolescents: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/suda-final-protocol.pdf
     October 02, 2018 - Randomized controlled trials (including cross-over trials)  N ≥10 participants per study group o Large … sample size from 1000 for when there are fewer than three similar studies, especially if there are large … For continuous outcomes we will consider small, modest, and large effects to correspond to standardized … other direction), moderate odds ratios that are between 1.2 and 2.0 (or between 0.83 and 0.5), and large … clinically important: For statistically significant difference with point estimates that are modest or large

106. Future Research Needs for Attention Deficit Hyperactivity Disorder: Effectiveness of Treatment in At-Risk Preschoolers, Long-Term Effectiveness in All Ages, and Variability in Prevalence, Diagnosis, and Treatment (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/adhd-future_research.pdf
     May 01, 2012 - Also, trials to evaluate harms will require lengthy duration and large sample sizes. … Scheduling and managing deliverables for a large group could present challenges. … Also in conference calls, stakeholders discussed the desire for a large, long-term, multisite trial … ClinicalTrials.gov Expert Search of all fields: D-5 Full “LARGE” search was completed and … ADHD search strings for RePORTER: “LARGE” search, inclusive of all ADHD terms used by McMaster

107. 8 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-harms_methods.pdf
     November 01, 2008 - observational studies usually report smaller absolute risks of harm than do large randomized trials … Observational studies based on analyses of large databases. … Pharmacoepidemiologic studies using large databases to identify exposures and outcomes may be valuable … If large, higher quality studies are available, it could be reasonable to specify a minimum sample … Observational studies based on evaluations of large administrative databases should follow the same

108. 8 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/methodsguide_chou_assessing_harms_when_comparing.pdf
     November 01, 2008 - observational studies usually report smaller absolute risks of harm than do large randomized trials … Observational studies based on analyses of large databases. … Pharmacoepidemiologic studies using large databases to identify exposures and outcomes may be valuable … If large, higher quality studies are available, it could be reasonable to specify a minimum sample … Observational studies based on evaluations of large administrative databases should follow the same

109. Disposition of Comments for CER 160 Binge Eating Disorder (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/binge-eating-disposition-160504.pdf
     December 09, 2015 - LOC eating typically refers to objective binge eating (eating an objectively large amount of food + … LOC) and subjective binge eating (eating a subjectively large amount of food + LOC). … However, given the very large number of studies that were excluded from the report, I wonder if there … They include increasing dose-response, large magnitude of effect and an effect that would be larger … In addition, samples (both large in size) were similar across the trials (i.e., mean age in the 40s,

110. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/pain-chronic_disposition-comments.pdf
     September 01, 2011 - My understanding is that economics plays a large role in CARF accreditation but an important topic. … This is a large barrier to their use. … Given the wide prevalence of the latter in society at large, one would have wished to see some comment

111. Menopause Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/menopause_executive.pdf
     March 01, 2015 - Compared with placebo, SMDs were in general not large (i.e., SMD between -0.5 and 0) for any of the … Therefore, findings from large observational studies with younger populations were incorporated to … However, given the large numbers of women potentially taking these agents, some caution is advised, … • A large number of nonprescription agents were studied in individual trials. … From a large body of evidence, there is considerable certainty that estrogens are the most effective

112. Disposition of Comments Report for Testing of CYP2C19 Variants and Platelet Reactivity for Guiding Antiplatelet Treatment (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/antiplatelet-treatment_disposition-comments.pdf
     September 25, 2013 - For this reason in several of the large trials we rated blinding (of “testing to outcomes” and of “ … As discussed below, most large “repurposed RCTs” were based on large well-conducted RCTs assessing … Again, we agree that the large repurposed RCTs included in our analyses were based on well-conducted … , large trials. … Several large studies included in the review reported information exclusively in this form.

113. Breast-Biopsy-Update Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy-update_executive.pdf
     September 01, 2014 - Theory and empirical work suggest that, when the number of studies is large, this approach produces … Selective outcome reporting was considered likely for all adverse events examined, because of the large … In contrast, the evidence base on core needle biopsy methods now includes a large number of studies … Although the magnitude of this association was large (the ratio of the odds was approximately 15), … We did not include studies published in languages other than English; however, given the very large

114. Grades-Predictive-Values White-Paper-2015 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/grades-predictive-values_white-paper-2015.pdf
     January 01, 2015 - In first trials with large treatment effects (>0.5 SMD), however, estimates of effect substantially … Exceptions are first trials that present large treatment effects which often dissipate as new evidence … evidence.3,4 Nevertheless, because reviewers cannot be certain that a single study, no matter how large … For first trials with large treatment effects (relative risk 0.5 and >2.00, or SMD>0.8), a change in … Empirical evaluation of very large treatment effects of medical interventions.

115. Disposition of Comments Report for Stroke Prevention in Atrial Fibrillation (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/stroke-atrial-fibrillation_disposition-comments.pdf
     August 23, 2013 - The large number of comparisons is exhaustive and it was sometimes difficult to prioritize the main … Do large population based studies report on the availability of hemoglobin values, platelet counts, … The report is heavily reviewed 3 currently completed large clinical trials, mainly RE-LY, ROCKET-AF … I don’t agree that a single trial, even a large one, provides this level of evidence. … TEP #3 Results KQ4 - large registries eg AFCAS have been published.

116. Disposition of Comments for Epoetin and Darbepoetin for Managing Anemia in Patients Undergoing Cancer Treatment (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-anemia-update_disposition-comments.pdf
     April 25, 2013 - It would also be appropriate to state more explicitly that despite the large number of trials of these … In the curative treatment setting, in a large trial involving patients with Hodgkin's disease treated … Page 100, line 28: The report should state more explicitly that, despite the large number of trials … BEST was large and judged a high quality trial, notwithstanding some criticisms. … In addition to the exclusion of the 2 large pharmacovigilance studies, there are limitations to the

117. Comments to Effective Heath Care Program Draft Documents (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/registries-guide-2nd-edition_disposition-comments.pdf
     March 03, 2010 - can make a meaningful contribution to understanding adverse event rates in that they can provide large … (Exception may be extremely large , comprehensive , national disease registers). … the exception may be extremely large, comprehensive national disease registry. … For example, a comparison of the value of a registry contrasted with a large simple safety study in … The authors point out that interoperability is critical to useful large‐scale healthcare information

118. Rotator-Cuff-Tear-Surveillance-140925 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/rotator-cuff-tear-surveillance-140925.pdf
     February 01, 2014 - Outcome of rotator cuff repair in large-to-massive tear with pseudoparalysis: a comparative study … Functional outcome and structural integrity following mini-open repair of large and massive rotator … Mihata T, et 2011 Functional and patients with full- SR, DR, and Retear rate For small and large and … Oh JH, et al.30 2011 Outcome of rotator cuff repair in large-to- massive tear with pseudoparalysis: … a comparative study with propensity score matching. 58 patients with large- to-massive rotator

119. FRN 35 - Preventive Pharmacological Treatments for Migraine in Adults: Future Research Needs (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-future_research.pdf
     April 01, 2013 - The large placebo response observed in studies on this topic creates another strong indication that … The large placebo response observed in studies on this topic creates another strong indication that … A large sample capable of testing these characteristics via subgroup differences is necessary. … A large sample capable of testing these characteristics via subgroup differences is necessary. … Large sample that allows subgroup analysis would provide most useful information.

120. Evidence Summary: Pharmacologic and Nonpharmacologic Therapies in Adult Patients With Exacerbation of COPD (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-221-copd-evidence-summary_0.pdf
     October 01, 2019 - experience mild to moderate dyspnea and may result in no requirement of systemic corticosteroids in a large … As these findings were based on single, relatively small studies, evidence from well- conducted large … vitamin D may improve quality of life in patients with ECOPD, but confirmation from well-conducted large … As these are resource-intensive interventions, large well-designed trials with final health outcomes … stimulation (TENS), dietary interventions with caloric supplements and vitamin D need to be assessed in large