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Total Results: 1,324 records

Showing results for "lack".

81. Disposition of Comments Report for Vitamin D and Calcium: A Systematic Review of Health Outcomes (Update) (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/vitamin-d-calcium_disposition-comments.pdf
    September 15, 2014 - The lack of agreed definitions is a persisting issue that can cause huge confusion to readerships. … the synopsis. 57 Peer Reviewer 2 Results Table 4 – For Hollis 2011, no comment is made about the lack … We have added text to clarify the lack of new studies. … The nature of the findings in terms of the sustained lack of conclusive and consistent evidence of … of baseline measures that undoubtedly contribute to the lack of effects seen in trials.

82. Medical Therapies for Children With Autism Spectrum Disorder—An Update (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/asd-medical-executive-170505.pdf
    May 01, 2017 - clear (little effect on 1 study and linear effect in another); SOE is low given small sample size and lack … harms reported in any study N-acetylcysteine vs. placebo 2 RCT (127) Social skills Low SOE for lack … clinically important Tetra- hydrobiopterin vs. placebo 2 RCT (54) Symptom severity Low SOE for lack … This lack of reporting makes comparing harms across studies difficult. … This lack of reporting makes comparing harms across studies difficult.

83. Disposition of Comments_Comparative Effectiveness Review No. 274: Diagnosis and Treatment of Tethered Spinal Cord (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-274-tethered-spinal-cord-disposition-comments.pdf
    October 25, 2024 - Several reviewers highlighted the lack of research for key outcomes and effect estimates. … The lack of studies for treatments other than surgical detethering is noted in the limitations section … It also acknowledges the limitations of the evidence, such as the lack of data on certain outcomes

84. Evidence Summary for Treatments for Acute Pain: A Systematic Review (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/cer-240-acute-pain-evidence-summary.pdf
    December 01, 2020 - Evidence Summary for Treatments for Acute Pain: A Systematic Review Comparative Effectiveness Review Number 240 Treatments for Acute Pain: A Systematic Review Evidence Summary Main Points Background and Purpose The purpose of this review is to evaluate the effectiveness and comparative …

85. Topic 0590 Strategies to Treat and Manage Infantile Hemangioma NSD FINAL_SJ (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0715-140408.pdf
    May 29, 2025 - The lack of guidance on the condition is reflected in the variation in clinical practice.

86. Omega-3 Fatty Acids and Maternal and Child Health: An Update (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/omega-3-maternity_executive.pdf
    October 01, 2016 - to assess whether adequacy of n-3 FA status might account for differences in outcomes across (or lack … Conclusions with strength of evidence for an effect or lack of effect (continued) aFigures represent … Across RCTs, the most common risk-of- bias limitation was a lack of intention-to-treat analyses (54 … Across observational studies, the most common risk of bias limitation was the lack of representativeness … This observation would seem to suggest that the apparent lack of effect of the intervention on the

87. Nonpharmacological Versus Pharmacological Treatment for Patients With Major Depressive Disorder: Current State of the Evidence (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/major-depressive-disorder_clinician.pdf
    September 01, 2016 - Rate Intervention Effect SOE Effect SOE Switching to another SGA as second-step therapy because of lack … SGAs) ��� ⬌ (among various SGAs) ��� Switching to another SGA versus switching to CBT because of lack

88. Infantile-Hemangioma Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/infantile-hemangioma_executive.pdf
    January 01, 2016 - Both medical and surgical treatment paradigms contain significant variability and lack of consensus … Overall, studies were limited by the size of cohorts, lack of standard processes, and lack of direct … Findings are limited by the size of cohorts, lack of standard processes, and lack of direct comparison … Low SOE for lack of association of timolol with harms based on few studies. … Low SOE for no difference between PDL treatment and observation in reducing lesion size due to lack

89. Effective Health Care (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0264_01-14-2008.pdf
    January 01, 2008 - The literature suggests there is a lack of evidence-based guidance for treatment of several disease

90. Effective Health Care (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0496_12-30-2011.pdf
    January 01, 2011 - Based on this increasing prevalence, a lack of up-to-date comprehensive guidelines and systematic reviews

91. Interventions Targeting Sensory Challenges in Children With Autism Spectrum Disorders - An Update (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/asd-interventions-disposition.pdf
    May 26, 2017 - Lack of independent replication seems to be a considerable flaw. … Behavior scale did not show differences but this was noted as due to short intervention period and lack … Results Based upon the description of the studies and their dissimilarities or methodological flaws (lack

92. Disposition of Comments Report for Local Therapies for Unresectable Primary Hepatocellular Carcinoma (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/liver-cancer-therapy_disposition-comments.pdf
    May 24, 2013 - report is clinically meaningful although comparative effectiveness research outcomes are limited by lack … It is clinically meaningful only in that it highlights the lack of available comparative effectiveness … TACE sections: I recommend insertion of a statement under strength of evidence sections noting "lack … In addition there is a statement that reflects the limitations due to the lack of comparative data. … the year 2000 Technical Expert #1 Results While the analysis appears very exhaustive, the Results lack

93. Making Healthcare Safer IV: Summary of Findings on Patient Safety Practices and Ratings by a Technical Expert Panel, 2024-2025 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-iv-patient-safety-practices-year-2.pdf
    May 01, 2025 - • The discussion focused on the lack of research on healthcare supply chains, despite their impact … The group agreed that simply stating "don't do it" due to lack of evidence is not a good option. … Barriers, Facilitators, and Resources o Barriers included a lack of leadership support, insufficient … resources, and a lack of engagement and training. … Specific topics were further limited by factors such as a lack of research (supply chain monitoring)

94. Effective Health Care (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0367_11-08-2010.pdf
    January 01, 2010 -  There is a lack of clear consensus or consistent recommendations regarding screening and treatment

95. Effective Health Care (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0311_06-17-2008.pdf
    January 01, 2008 -  Due to the lack of guidance on how to interpret troponin scores in patients with renal disease

96. Effective Health Care (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0440_06-01-2011.pdf
    January 01, 2011 -  Given the lack of studies found on the topic, a full systematic review evaluating the comparative

97. Disposition of Comments CER 219 Antipsychotics for the Prevention and Treatment of Delirium (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/delirium-disposition-comments.pdf
    September 03, 2019 - Moreover, most hospitals are far behind in delirium practices, including management, lack of knowledge … We have tried to make clear throughout where there is evidence for lack of effect versus a lack of … TEP Peer Reviewer #2 Overall This is a well-written report that unfortunately highlights the lack … handful exist, I wonder if there was an exclusion criteria that removed these papers (such as the lack … (“Though frequently used in patients with delirium or those at risk of delirium, there remains a lack

98. Effective Health Care (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0430_04-22-2011.pdf
    January 01, 2011 - Because of the high prevalence of urinary retention and the lack of evidence-based guidelines addressing

99. Ch 9-User-Guide-To-Ocer 130129 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/ch_9-user-guide-to-ocer_130129.pdf
    September 21, 2012 - Without the context of a numeric rationale for the study size, readers may misinterpret the lack of … a statistically significant difference in effect as false reassurance of lack of harm, or falsely … Because retrospective studies lack a protocol for data collection, they often suffer a higher frequency

100. Chronic Kidney Disease Stages 1-3: Screening, Monitoring, and Treatment (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-disease-medicine_disposition-comments.pdf
     August 01, 2012 - Lack of evidence on effectiveness of screening vs. … We agree with the reviewer that lack of evidence is not equivalent to negative evidence. … for a lack of effect. … Lack of evidence on effectiveness of screening vs. Evidence that screening is ineffective. … for a lack of effect.