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  1. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND__0355_09-22-2010.pdf
    January 01, 2010 - Completion Date: 05-19-11 2  Insomnia is defined as the inability to initiate or maintain sleep or a lack
  2. effectivehealthcare.ahrq.gov/sites/default/files/related_files/progestogens-preterm-birth-disposition-121205.pdf
    September 07, 2012 - We share concerns about lack of safety data and have amplified that in the final version of the report … Moderate strength of evidence indicates lack of effectiveness for multiple gestations. … Across other forms, the studies lack similarity in indication and use. … We have noted in multiple locations that lack of sufficiently large studies to understand this risk … The lack of precision noted here relates to the varying definitions of these rare events and their
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/effect-protein-intake-executive-summary.pdf
    November 01, 2024 - outcome measurement methods with inherent limitations, the absence of sarcopenia as a study endpoint, lack … Ambiguities stem from study limitations, lack of studies on vital demographics such as children and
  4. Naik (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/naik.pdf
    January 01, 2009 - Electronic Medical Record  Systems o Disadvantages  Potential gaps in  accountability for roles  Lack … Reliance on synchronous and explicit communication o Redundancies in routine, usual, and expected care o Lack
  5. effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-children-future_research.pdf
    February 01, 2012 - .5-9 Prescribing antipsychotics to the pediatric population is controversial because of a relative lack … KQ 3, Methods The extant literature demonstrates a lack of consensus on minimal clinically important … Further, where there is a perceived or real lack of equipoise (e.g., in comparing FGAs versus … Stakeholders made special note of the lack of patient registries with linkages to clinical datasets … The extant literature demonstrates a lack of consensus on minimal clinically important differences
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/evidence-summary-cer-199-skin-cancer.pdf
    December 01, 2017 - of histologic clearance, and lack of clinical clearance. … Lack of Histological Clearance In total, 15 RCTs (1940 lesions) were included in this analysis, and … In general, the mean fractions for lack of histologic clearance for individual interventions are in … Lack of Clinical Clearance In Table C the fraction of lesions without clinical clearance was between … The lack of evidence comparing efficacy among these commonly used treatments is striking.
  7. effectivehealthcare.ahrq.gov/sites/default/files/related_files/preterm-birth-terbutaline-pump_disposition-comments.pdf
    September 01, 2011 - This lack of inclusion of sonographic cervical length or fibronectin among the inclusion criteria of … with adverse effects, have large numbers (9357 and 8709), (respectively) and speak strongest to the lack … Lastly, many of the articles with good data on efficacy (and safety) were not analyzed due to the lack … This lack of inclusion of sonographic cervical length or fibronectin among the inclusion criteria of … The conclusions lack a discussion of the low quality of studies from which the results were obtained
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/patient-centered-medical-home_disposition-comments.pdf
    July 03, 2012 - We have reiterated the lack of consensus concerning the definition of PCMH. … This lack of standard definitions also leads to a wide variety of measures for PCMH components. … This lack of standard definitions also leads to a wide variety of measures for PCMH components. … The lack of evidence from large-scale studies is largely due to a lack of funding for these studies, … We agree that there is a lack of agreement concerning the definition of PCMH.
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-cancer-imaging_disposition-comments.pdf
    October 01, 2014 - Commentator & Affiliation Section Comment Response Findings (continued) Page 14 line 11: LackLack data on 18F-FNa PET/CT Page 14 line 28: Sentence incorrect. … Future studies should address lack of appropriate clinical outcomes as well as patient centered outcomes … , and a lack of evaluation of quantitative imaging vs qualitative imaging. … The Draft Technical Brief points to lack of studies on “clinical and patient centered outcomes”.
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/monitoring-programs-rapid-research.pdf
    April 01, 2025 - of resources to implement data standards • Duplication of core activities • Lack of information … technology capacity • Need for training supply chain professionals • Lack of trust/partnerships with … The lack of empirical evidence on the impact of healthcare supply chain monitoring programs on patient … applicable and which are not. 4.3 Implications for Clinical Practice and Future Research The lack … Given the current lack of empirical studies, any study design providing data on the effectiveness of
  11. effectivehealthcare.ahrq.gov/sites/default/files/pdf/icd-categories-prevalence-reimbursement_research.pdf
    January 01, 2011 - referral region 2006 2009 2.4 – 5.9 5.9 – 6.7 6.7 – 7.5 7.5 –13.9 White corresponds to areas that lack … referral region 2006 2009 1.8 – 3.9 3.9 – 4.3 4.3 – 4.8 4.8 – 8.7 White corresponds to areas that lack … region 2006 2009 0.07 – 1.03 1.03 – 1.13 1.13 – 1.24 1.24 – 1.71 White corresponds to areas that lack … region 2006 2009 Small cell 1.2 – 3.3 3.3 – 3.9 3.9 – 4.4 4.4 – 7.5 White corresponds to areas that lack … region 2006 2009 Small cell 1.4 – 3.8 3.8 – 4.4 4.4 – 5.1 5.1 – 9.3 White corresponds to areas that lack
  12. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-222-evidence-summary-health-equity.pdf
    January 01, 2020 - • Evidence is low or insufficient for other interventions due to lack of studies or their limitations … barrier was type of insurance coverage, however, results of studies were mixed, as were results for lack … Current evidence on achieving health equity in preventive services is limited primarily by the lack … Results of studies were mixed for type of insurance coverage and lack of a regular healthcare provider … Evidence is low or insufficient for most other interventions and outcomes because of the lack of
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/lung-cancer-nonsurgical-therapies_executive.pdf
    June 01, 2013 - Data Synthesis and Analysis Given the lack of appropriate comparative studies for all Key Questions … This study was considered to have serious risk of bias, primarily because of lack of adjustment for … Lack of Clinical Trial Evidence on Local Nonsurgical Interventions for Stage I NSCLC As part of this … We identified a number of research gaps during the course of review: • Lack of comparative evidence … However, neither of these trials were completed due to lack of patient accrual.
  14. effectivehealthcare.ahrq.gov/sites/default/files/related_files/autism-adolescents_executive.pdf
    August 01, 2012 - of adult services and long waiting lists for many services.7,8 This issue of the lack of services available … • Lack of comparison groups in 3 studies; treatment adherence not reported; assessors not masked … The lack of randomized, controlled trials is notable in all categories of intervention, but especially … To some degree, this reflects a lack of understanding and consensus about optimal outcomes and how to … Conclusions Given the number of individuals affected by ASD, there is a dramatic lack of evidence on
  15. effectivehealthcare.ahrq.gov/sites/default/files/diabetic-neuropathy-disposition-170707.pdf
    March 24, 2017 - & Affiliation Section Comment Response TEP #2 Results – KQ2 I’m guessing that it was due to a lack … Similarly, were dropout rates due to lack of efficacy assessed? … We did not assess dropout rates due to lack of efficacy, as this would have been accounted for in the … 3) The SNRI to anticonvulsant comparison is from Griebeler et al which is quite limited because of lack … One of the problems in these reviews is the lack of any RCTs involving old therapies.
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/diabetic-neuropathy-disposition-170707.pdf
    March 24, 2017 - & Affiliation Section Comment Response TEP #2 Results – KQ2 I’m guessing that it was due to a lack … Similarly, were dropout rates due to lack of efficacy assessed? … We did not assess dropout rates due to lack of efficacy, as this would have been accounted for in the … 3) The SNRI to anticonvulsant comparison is from Griebeler et al which is quite limited because of lack … One of the problems in these reviews is the lack of any RCTs involving old therapies.
  17. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-257-antenatal-care-evidence-summary.pdf
    June 01, 2022 - difficulty for patients in the initial set-up; difficulty for patients to describe symptoms virtually; lack … concerns about potentially liability issues and changes in reimbursement policies; limited evidence (or lack …  Tradeoffs of barriers and facilitators from provider perspective: lack of privacy for televisits
  18. effectivehealthcare.ahrq.gov/sites/default/files/related_files/evidence-map-technical-brief-49-disposition-comments.pdf
    September 05, 2024 - Ln49-52: It seems like the gap stems from the lack of person-centered indicators being measures... … perhaps rephrase to emphasize that person-centered planning approaches lack rigorous metrics to assess … It is not surprising that the authors found a lack of emphasis on person- centered interventions and … However, the authors rightly point out that the lack of person-centeredness remains an important gap … Summary Findings: The executive summary highlights important gaps in the literature, such as the lack
  19. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-254-rural-telehealth-executive-summary.pdf
    December 01, 2022 - provider time, technology, and other resources, as well as limited understanding of the rural context and lack … o Lack of control for confounders related to patients, providers, facilities, and differences in telehealth … most frequently identified weakness after overall study design is small sample sizes that result in lack
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/aggression_disposition-comments.pdf
    July 14, 2016 - The definitions and diagnostic criteria for the outcomes are well defined but do point out the lack … The particular importance in this review is lack of data points across studies rather than a problem … risk assessment, multimodal, environmental, and medication protocols are limiting with a noticeable lack … Based on the lack of sufficient evidence and the review, this was like comparing apples to grapes to … Discussion/Conclusion TEP #5 I would again encourage highlighting the tension that a lack of evidence

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