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Total Results: 1,324 records

Showing results for "lack".

341. Abnormal-Uterine-Bleeding Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/abnormal-uterine-bleeding_research-protocol.pdf
     November 21, 2011 - dysfunction or endometrial processes. 17 While the underlying causes may vary, for instance from lack … regulation of the hypothalamic- pituitary-ovarian axis in teens near the onset of menses, and from lack … likely beneficial for treatment of anovulatory (i.e., acyclic) abnormal uterine bleeding but there is lack … review of the literature and input from experts during the topic refinement process, studies may lack

342. Evidence-based Practice Center Technical Brief Protocol: Disparities and Barriers for Pediatric Cancer Survivorship Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/pediatric-cancer-survivorship-protocol.pdf
     June 01, 2020 - adulthood.4 Barriers to survivorship care are seen at many levels, including the patient and caregiver (lack … late effects and need for follow-up care), provider (inability to care for the complexity needed or lack … The lack of rigorous assessment of strategies to reduce barriers, and the fragmented nature of existing

343. FRN 39 - Nonoperative and Operative Treatments for Rotator Cuff Tears: Future Research Needs (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/rotator-cuff-tears-future_research.pdf
     February 01, 2013 - paucity of evidence on early versus delayed surgery (one trial) was a noted concern because of the lack … Consumers lack knowledge about which rotator cuff injuries need surgery and how to find information … spectrum of rotator cuff evaluation and treatment was the way in which provider specialization, or lack … Potential risk from inaction: - Unintended harms from lack of prioritization of a nominated topic … • There is a lack of public understanding of which rotator cuff injuries really need surgery.

344. Interventions-Horizon-Scan-High-Impact-1306 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/interventions-horizon-scan-high-impact-1306.pdf
     June 01, 2013 - it is intended to provide a means of extending the reach of primary care providers to patients who lack … experts were uncertain about this device’s potential to improve patient health outcomes, citing a lack … that this intervention has potential to improve patient outcomes, although some experts noted the lack … However, expert enthusiasm for the model was tempered by the lack of outcomes data and the opinion … Although several experts noted the lack of outcomes data regarding this intervention, most experts

345. Methods White Paper: Improving the Utility of Evidence Synthesis for Decision Makers in the Face of Insufficient Evidence (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/improving-utility-evidence-synthesis-white-paper.pdf
     April 01, 2021 - Although the reasons for rating evidence as insufficient frequently pertained to imprecision and lack … (e.g., the systematic review was an update of a previous one, or scoping the literature indicated lack … of directness, lack of precision, and publication bias Comparative Effectiveness of Analgesics … Lack of evidence (for subgroup analyses of interest) 3. … Lack of evidence/no studies KQ 7.

346. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-2007_executive.pdf
     January 01, 2007 - combination of metformin with a sulfonylurea and monotherapy with a sulfonylurea or metformin, due to lack … of adjustment for key confounders in cohort studies and lack of studies evaluating this combination. … combination of metformin with a sulfonylurea and monotherapy with a sulfonylurea or metformin, due to lack … of adjustment for key confounders in cohort studies and lack of studies evaluating this combination. … One limitation of this interim analysis was the lack of power to detect differences because of lower

347. Disposition of Comments for CER 178 Newer Medications for Lower Urinary Tract Symptoms (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/prostatic-hyperplasia-medications_disposition-comments.pdf
     May 26, 2016 - thereof) versus traditional medications, an evaluation of adverse effects, and analysis that includes a lack … We analyzed the dosages separately to see if lack of difference may be due to the lower dose of tamsulosin … The lack of definition of MID in the questionnaires is clearly problematic, but the authors' strategy … Results Line 47-54, Page 17 This is quite liable to bias given the nature of the report and the lack … We mentioned the lack of blinding in the results section.

348. Obesity (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/10_obesity_potential_high_impact_2012-12-11.pdf
     January 01, 2012 - The committee stated “the lack of obesity medications is a significant unmet medical need.” … meet the need of patients who are obese for a medical solution for moderate weight loss, given the lack … $120 and $185 per month. 4,10 Concerns exist regarding patient out-of-pocket expenses because of lack … combination expressed optimism about its ability to meet the need of patients who are obese, given the lack … associated with diabetes, citing the increasing prevalence of obesity in the United States and the current lack

349. Menopause Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/menopause_executive.pdf
     March 01, 2015 - individually in the presence of clinical heterogeneity; as stated by Treadwell and colleagues, “the lack … potentially attributable to older age and less symptom severity of enrolled women in these trials or the lack … initial intent was to examine subgroups according to characteristics such as the presence of a uterus, lack … Research Gaps The principal gaps in the evidence on symptom relief include lack of common validated … instruments and assessment of meaningful clinical improvement; safety data on nonprescription agents; lack

350. Arthritis and Nontraumatic Joint Disease (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/01_arthritis_potential_high_impact_2012-12-10.pdf
     January 01, 2012 - Additionally, the current lack of third-party payer coverage and high out-of-pocket costs for patients … Additionally, the current lack of third-party payer coverage and high out-of-pocket costs for patients … Some experts agreed that lack of third-party payment for MSC therapy and its implementation in specialty … patients may be highly interested in new, effective, nonsurgical treatment for their OA, current lack … Other experts thought the experimental nature and lack of reimbursement currently associated with the

351. Total Worker Health® (TWH) (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/worker-health_executive.pdf
     April 01, 2016 - Of particular note is the lack of representation across regions of the United States and the appreciable … without a control group are unlikely to yield meaningful information about the effectiveness (or lack … It is of particular importance for future research to deal with the following problems: lack of reporting … of power for determining intended effects), lack of clarity in defining intervention components, and … lack of adequate description or documentation of statistical tests and results.

352. Research White Paper Patient- or Participant-Generated Registries Addendum Registries for Evaluating Patient Outcomes Third Edition (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/patient-participant-generated-registries-guide-3rd-ed-addendum-white-paper.pdf
     February 01, 2018 - Quality and Data Standards PGRs face challenges related to data quality, particularly with regard to lack … of uniform data collection, insufficient data quality checks, and lack of validation through medical … One example of lack of uniformity is that PGRs may offer participants the opportunity to enter data … Additional variability can be introduced by lack of uniform measurement tools, e.g., reporting weight … Lack of verification of data through medical record review or contact with health care providers can

353. Improving Health Care and Palliative Care for Advanced and Serious Illness Disposition of Comments Report (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/quality-gap-palliative-hospice_disposition-comments.pdf
     October 01, 2012 - For me the key finding is the lack of research - with a priority being looking at QI interventions in … methods are often missing in design and control, and that various populations or disease/conditions lack … quality improvement studies.“ 15 5 Discussion/ Conclusion The future research areas related to lack … to a) use of terms "quality improvement" and "end of life", b) confusing Results organization, lack … However, lack of blinding is cited as a criticism throughout the Results section.

354. Antidepressant Treatment of Depression During Pregnancy and the Postpartum Period (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-pregnancy-postpartum_executive.pdf
     July 01, 2014 - insufficient to draw conclusions because of inconsistency and imprecision; it generally suffered from lack … comorbidities, such as drug and alcohol misuse or abuse, other Axis I disorders, and suicidal ideation; lack … relevance of the nonpharmacological treatment modalities was difficult to assess because of a general lack … relevance of the pharmacological treatment regimens was difficult to assess because of a general lack … the defined scope included the exclusion of studies published in languages other than English and lack

355. Comparative Effectiveness Review No. 272_Genitourinary Syndrome of Menopause: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-272-genitourinary-syndrome-executive-summary.pdf
     July 01, 2024 - Given the range of symptoms associated with GSM, the lack of definitive diagnostic criteria, impact

356. Disposition of Comments Report for Otitis Media With Effusion (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ear-infection_disposition-comments.pdf
     May 04, 2013 - The overriding importance of understanding the limited generalizability of the evidence and our lack … The uncertainty stems from the lack of consensus regarding the clinical and functional outcomes of … The lack of generalizability is an important message, one that (as stated above) is not even mentioned … ES-8, line 20-27: The lack of any quantitative information here really limits the utility of results … Suggested change: This is the place to comment on the disturbing lack of information on subgroups most

357. Disposition of Comments for Psychological Treatments and Pharmacological Treatments for Adults With Posttraumatic Stress Disorder (PTSD) (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-adult-treatment_disposition-comments.pdf
     April 03, 2013 - It does not indicate that a treatment has been proven to lack efficacy.” 8 Anonymous Public Reviewer … In addition, though, there need to be other caveats, such as lack of readiness for some treatments ( … low risk of bias rating, with any unfavorable responses being of relatively minor concern (e.g., lack … The lack of masking was factored in to our risk of bias assessment of the study, and that information … decrease the likelihood of seeking treatment (e.g., age, marital status, race, comorbidities), lack

358. Disposition of Comments Report for Technical Brief 15 Transition Care for Children With Special Health Needs (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/children-special-needs-transition_disposition-comments.pdf
     June 17, 2014 - Peer Reviewer 12 General This is a much needed and well-written report that summarizes the lack of … outside of health systems; the challenge of robust transition teams in independent practices due to the lack … Thank you for the comment Peer Reviewer 8 Findings We still lack research on what is normative development … In addition, the need for family-centered care, the lack of insurance coverage, the lack of natural … The conclusions are definitely clear about the lack of work in this area. Thank you.

359. Antibody Response Following SARS-CoV-2 Infection and Implications for Immunity: Final Update of a Rapid, Living Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/version-3-immunity-after-COVID-19.pdf
     December 31, 2022 - Retired due to lack of relevance after widespread vaccination campaigns. … Third, most studies were small (fewer than 200 participants), leading to lack of precision in estimates … studies were limited by high potential for unmeasured confounding, and in some cases, inadequate or lack … Lack of antibodies to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in a large cohort

360. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-disease-ace-inhibitor-arb-disposition.pdf
     March 10, 2010 - Since the lack of evidence does not mean lack of effect, I recommend changing this to state that the … evaluating ACE inhibitors alone provides data very similar to that of the prior paper, mainly due to the lack