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  1. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-220-disposition-comments-analgesics-prehospital-setting.pdf
    September 03, 2019 - Peer reviewer #3 Methods p7 line 55: " low rating implies lack of major or minor sources of bias … reviewer #1 Discussion -Page 71: The authors should also include the following limitations: the lack … of evaluation of non- pharmacologic methods to address pain and the lack of PO routes compared for … medications We added comments about lack of oral route studies in the future research needs section … the limitations of the review given available literature but is impactful in clearly stating the lack
  2. effectivehealthcare.ahrq.gov/sites/default/files/related_files/mrsa-screening-2010_disposition-comments.pdf
    January 01, 2010 - are some key points made that limit the usefulness of the information presented -- specifically, the lack … Peer) General General Comments: In the grading of the strength of evidence, there appears to be lack … Strength of evidence is lowered by the high risk of bias and the lack of precision. … because of the lack of a formal assessment of agreement between reviewers. … In fact, despite the lack of robust controls in the majority of studies evaluated, implementation of
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/tech-brief-31-mobile-applications-self-mgmt.pdf
    May 01, 2018 - Our rationale was that, while lack of masking of treatment assignment can introduce bias, this bias … Therefore, although we did not formally evaluate the lack of masking of participants and providers in … This study was low quality due to inconsistent reporting of outcomes as well as lack of information … This study was low quality due to a lack of information on randomization and allocation concealment, … lack of information on how drop-out data was analyzed, and limited information on whether baseline
  4. effectivehealthcare.ahrq.gov/sites/default/files/related_files/behavioral-health-screening-disposition-comments.pdf
    April 09, 2025 - 1 Discussion As described above, there may be important lessons that are missed because of the lack … Peer Reviewer 3 Discussion The evidence gaps (including the lack of any studies on implementation … of anxiety screening, lack of studies assess equity, and the lack of many prioritized outcomes) are … Public Reviewer: Richard Lawhern All The lack of positive results from this systematic review is … We agree that lack of reimbursement is a barrier, as we noted in the Introduction.
  5. effectivehealthcare.ahrq.gov/sites/default/files/related_files/traumatic-brain-injury-rehabilitation_executive.pdf
    June 01, 2012 - Uncertainty about which patients are likely to benefit from specific rehabilitation programs contributes to lack … The most common reason for exclusion was the lack of a comparison group; 59 studies were excluded on … Other common reasons for exclusion included the lack of an intervention, lack of a primary or secondary … Despite the lack of a consistent taxonomy, interventions could be grouped on several levels. … Knowledge of which treatments are most effective is less likely to benefit those who lack insurance
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/juvenile-arthritis-dmards_disposition-comments.pdf
    September 01, 2011 - Peer Reviewer #2 Executive Summary Likewise with regard to lack of radiographic data – it might be … helpful to have a notation regarding lack of standardization and difficulty reading films on joints … APPROPRIATE given that the answer to the most meaningful key question, #4, is not obtainable due to lack … authors state that a study on anakinra was rated as poor because of insufficient statistical power, lack … Although the conclusions are less likely to guide therapy based on the lack of strong evidence either
  7. effectivehealthcare.ahrq.gov/sites/default/files/pdf/cesarean-birth-2010_research-protocol.pdf
    January 01, 2010 - cesarean births) as “suggest[ing] a pattern of almost random decision making” and “reflect[ing] a lack … Given a lack of translation resources, we will also focus the review on studies published in English … determine if the data are appropriate to conduct quantitative syntheses such as meta- analyses (i.e., lack
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/lifecycle-assessment-disposition-comments.pdf
    November 20, 2024 - Excluded because of lack of data? … It was not included in the systematic searches due to lack of access to the database. … Conference abstracts were not eligible due to the lack of detail for data abstraction. … The answer given is a lack of data. … reviewer #2 Findings On page 21, the paragraph starting at line 31 refers to barriers, including a lack
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/rheumatoid-arthritis-medicine_executive.pdf
    April 01, 2012 - Certolizumab pegol had fewer withdrawals due to lack of efficacy than adalimumab, anakinra, and infliximab … All but adalimumab, golimumab, and infliximab had fewer withdrawals than anakinra due to lack of efficacy … Common problems for RA studies included the lack of effectiveness information, that is, studies and
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-249-malnutrition-disposition-comments_0_0.pdf
    October 13, 2021 - While we noted that the report does mention ADLs and lack of information on ADL changes as markers … Peer Reviewer 2 General Comments In general, it appears the lack of a pre-step such as a scoping … I am unsure if this was excluded due to lack of data or validity which is probable. … Clear implications and description of the issues related to lack of standard descriptions. … The discrepancies in practice with regard to proper coding and lack of consensus approach (although
  11. effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-failure-natriuretic-peptide_disposition-comments.pdf
    November 20, 2013 - This is reflected in our findings Rev 1 disc Diagnosis: thanks largely to a lack of industry focus … The statement on P 24, line 39 regarding a lack of consensus for optimal cut-offs is actually not true—the … Rev 1 ES Relative to the lack of cost-effectiveness commented upon on Page 36, line 23, bullet 7: there … the prognostic studies was particularly well done given the challenge of inconsistent reporting and lack … Rev 8 Introduction The first concern is the lack of context.
  12. effectivehealthcare.ahrq.gov/sites/default/files/related_files/nephropathy-contrast-induced_disposition-comments.pdf
    January 07, 2016 - This is partially due to lack of prophylaxis but also that in the setting of acute coronary syndromes … Would it be safe in stating that, given the lack of other proven alternatives, it would be reasonable … by citing Nash et al and claiming that CIN is a leading cause of hospital-acquired AKI, despite the lack … It is not clear to me how many potential interventions were assessed and rejected because of lack of … We did not meta-analyze this data due to differences in reporting, or lack of data on the specific
  13. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0491-140827.pdf
    February 19, 2014 - . § There is a lack of consensus among clinicians about the best imaging modalities to aid in diagnosis
  14. effectivehealthcare.ahrq.gov/sites/default/files/related_files/acs-pci-adjunctive-devices_surveillance.pdf
    April 01, 2013 - MHRA (UK) Expert Opinion EPC Investigator Other Experts Conclusion from SCEPC analyses and lackLack of long-term clinical benefit of thrombus aspiration during primary percutaneous coronary intervention … Conclusion #4 Given the inadequate power in overall analyses and lack of data, we could not definitively
  15. effectivehealthcare.ahrq.gov/sites/default/files/web-based_dubenske_presenter.pdf
    January 01, 2009 -   • Critical  to  match  intervention  to  need   • Technology  as  barrier:   o Lack
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/pneumonia-antibiotic-treatment_disposition-comments.pdf
    November 24, 2014 - Executive Summary The Executive Summary on page ES-1 or page 8/95, is well done and underscores the lack … There was a lack of data to support the use of continuous infusion of betalactam antibiotics compared … Commentator & Affiliation Section Comment Final Response TEP Reviewer #6 General Comments The lack … We agree that the lack of evidence is frustrating. … The lack of studies linking PK/PD to clinical (patient-centered) outcomes in this setting has been
  17. effectivehealthcare.ahrq.gov/sites/default/files/related_files/long-term-care-adults_disposition-comments.pdf
    November 07, 2012 - “Lack of safety” can be a harm. … On page 53, lines 15-16, you do report as a research gap the lack of subgroup analyses by socio-economic … addressing the key questions that were determined prior to the review, so we are explicit about the lack … Reviewer #6 Discussion There should be some discussion of the lack of subgroup analysis prior to the … Reviewer #9 Discussion Discussion-47: A more extended discussion of quality of life and the lack of
  18. effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-emergency_disposition-comments.pdf
    November 27, 2012 - The report reflects the lack of strong evidence favoring a specific medical therapy for acute management … The authors must justify their focus on parenteral agents and provide some references to the (lack … Because of the lack of consistency throughout the paper, after reading it, I was still not sure what … Peer Reviewer #4 Discussion/conclusion This report exposes the lack of evidence support the use of … Once again, because of the lack of consistency in the way neuroleptics were handled, I was unsure how
  19. effectivehealthcare.ahrq.gov/sites/default/files/cer-240-acute-pain-revised-comments.pdf
    December 29, 2020 - Lack of detail about conclusions in summary points. … Also clarified the lack of homogeneity amongst studies which made it difficult to stratify results based … Evidence Summary There are a lot of might and maybe statements in this report which intimates a lackLack of such instruments is acknowledged in the report, but no explanation for the reasons associated … It is illegal drugs that are causing our problem and lack of education of our citizens.
  20. effectivehealthcare.ahrq.gov/sites/default/files/cer-230-prostate-cancer-comments.pdf
    September 17, 2020 - • The reviewers noted lack of clarity in the Introduction as the guideline recommended and practical

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