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Total Results: 1,324 records

Showing results for "lack".

141. Disposition of Comments for Technical Brief 28 MAT Models (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/opioid-use-disorder_disposition-comments.pdf
     December 06, 2016 - As demonstrated by the lack of research inclusive of pharmacists relied upon in the Brief, pharmacists … These barriers include stigma and misinformation, lack of funds to pay for treatment, loss of family … of institutional support, lack of prescribing physicians, and inadequate reimbursement described in … Propose restating: Lack of control over purity leading to high variability in dose is an additional … Overall lack of societal funding for treatment of OUDs remains an issue.

142. Disposition of Comments: Comparative Effectiveness Review No. 238 Cervical Ripening in the Outpatient Setting (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-238-cervical-ripening-outpatient-setting-comments.pdf
     March 22, 2021 - Further, the conclusion should reflect that there is no evidence of fetal safety due to the lack of … With regard to the comments on "no evidence of fetal safety due to the lack of inclusion of fetal … studies, the low and insufficient strength of the studies, the rare adverse outcome in thoses samples, lack

143. Wheeled Mobility (Wheelchair) Service Delivery (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/wheelchair-service_disposition-comments.pdf
     January 01, 2012 - This impacts the key questions; confusion and lack of clarity are the result of inadequate definition … However, we have concern that the lack of funding for many of the steps in the assessment process ( … Peer Reviewer #6 Discussion/ Conclusion The focus of the paper seems to be on the lack of research … Perhaps the focus should be on the lack of trained physicians being a barrier to this process. … Peer Reviewer #7 Discussion/ Conclusion Provider issues should include lack of education regarding

144. Effective Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0371_11-23-2010.pdf
     January 01, 2010 - In addition, a lack of clarity regarding the definition of performance metrics, quality measures, and

145. Effective Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND__0399_01-07-2011.pdf
     January 01, 2011 - Although there is a wide range of options for local treatment of liver malignancies, there is currently a lack

146. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy_disposition-comments.pdf
     March 11, 2010 - palpable lesions separately from non-palpable lesions but were unable to come to any findings because of lack … Due to lack of reporting of details by the primary studies we were unable to perform any further analyses … Methods p. 18 add “for Question 3 due to the nature of the question and lack of published data on the … We also agree that lack of reporting of funding sources is a problem with quality assessment, as is … the lack of a mechanism for dealing with less tangible benefits that may bias study outcomes, such

147. Arthritis and Nontraumatic Joint Disease (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-1406.pdf
     June 01, 2014 - Additionally, limited diffusion, lack of reimbursement, and high out-of- pocket costs to patients were … Additionally, experts stated that lack of clinical data made assessing the potential health impact … osteoarthritis (OA) interventions in which experts perceived considerable unmet need because of a lack … Study results are limited at this time because of lack of controls, high variability in MSC preparations … Additionally, the current lack of third-party payer coverage and high out-of-pocket costs for patients

148. Slide 1
     effectivehealthcare.ahrq.gov/sites/default/files/study-size-planning-chapter-9.pptx
     January 01, 2013 - Without the context of a numeric rationale for the study size, readers may misinterpret the lack of a … statistically significant difference in effect as false reassurance of lack of harm or falsely conclude … Because retrospective studies lack a protocol for data collection, they often suffer a higher frequency

149. Executive Summary_Systematic Review: Psychosocial and Pharmacologic Interventions for Disruptive Behavior in Children and Adolescents (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/disruptive-behavior-disorders-research-executive-summ.pdf
     April 01, 2025 - children are appropriately diagnosed and treated for DBDs, which includes addressing barriers such as lack

150. Comparative Effectiveness Review No. 234 Evidence Summary: Management of Primary Headaches in Pregnancy (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-234-headaches-pregnancy-summary.pdf
     November 01, 2020 - We deemed individual studies to have high or moderate risk of bias, most commonly due to lack of adjustment … for confounders; lack of blinding of participants, personnel, and outcome assessors; and/or incomplete

151. Disposition of Comments for Technical Brief 22 Environmental Cleaning for the Prevention of Healthcare-Associated Infections (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/healthcare-infections_disposition-comments.pdf
     August 10, 2015 - Problem is lack of agreement on the merits of the evidence and if the evidence is biased. … Many of these studies lack active engagement and were more directive of staff activities. … KI Reviewer 4 Findings P 19 line 11 - If there are data on lack of correlation with visual inspection … We agree that there is a lack of consensus on the value of outsourcing, but we needed to address the … Presently we include information on the study design limitations which include a lack of comparative

152. Maternal Morbidity and Mortality (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/mmm-draft-protocol-amendment.pdf
     February 02, 2022 - during and after pregnancy, but, also, the resulting void of information is further compounded by lack … substance misuse is affected by social factors such as race and ethnicity,23, 24 stable housing,25 lack … health systems, quality of clinical care (health-facility factors); missed or delayed diagnosis and lack … ● Lack of access to different models due to coverage/cost – e.g. group prenatal care, midwifery … care and in the community (e.g., incarceration/ policing/police violence) ● Medical mistrust ● Lack

153. Disposition of Comments Report for CER 132 Combination Therapy Versus Intensification of Statin Monotherapy: An Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-cholestorol-medicines-update_disposition-comments.pdf
     September 01, 2014 - Our systematic review update provided the evidence base (or lack thereof) to support our conclusions … Search strategy is reasonable generally, with the exception of some lack of clarity about the reason … “Implications for Clinical and Policy-Decision Making” Another issue facing clinicians is whether lack … men with low baseline HDL-c We have added to the Key Findings portion of the discussion that the lack … Implications for Clinical and Policy-Decision Making” Another issue facing clinicians is whether lack

154. Psoriatic Arthritis Surveillance Assesment_CER 54_Low (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/arthritis-psoriatric_surveillance.pdf
     March 01, 2013 - inhibitors found that both TNF inhibitors and sulfasalazine are effective (similar withdrawals due to lack … inhibitors found that both TNF inhibitors and sulfasalazine are effective (similar withdrawals due to lack … Male sex, CRP level > 10 mg/liter, concomitant Not stratified by drug. 44% stopped drug due to lack …  inhibitors  and  sulfasalazine  are   effective  (similar  withdrawals  due  to  lack … inhibitors  and   sulfasalazine  are  effective  (similar  withdrawals  due   to  lack

155. Antibiotics-Respiratory-Infection Clinician (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/antibiotics-respiratory-infection_clinician.pdf
     March 01, 2016 - ��Assessing how to optimize the use of effective interventions was precluded by the lack of sufficient … or LRTI in primary care 1 RCT ��� — No difference in hospitalizations or combined adverse effects/lack

156. Disposition of Comments for CER 211: Drug Therapy for Early Rheumatoid Arthritis: A Systematic Review Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-211-rheumatoid-arthritis-disposition-comments.pdf
     December 20, 2018 - As we comment below, due to the lack of agreement on the definition of early RA, existing evidence … We viewed lack of adherence as an undesirable event. … We agree that lack of adherence can have other reasons than harms (e.g., lack of efficacy). … We agree that lack of adherence can have other reasons than harms (e.g., lack of efficacy). … We viewed lack of adherence as an undesirable event.

157. Venous-Ulcers-Treatment Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/venous-ulcers-treatment_executive.pdf
     January 01, 2014 - The studies were all limited by sample size issues, selection bias, data heterogeneities, and lack of … Understanding the efficacy of surgical approaches is complicated by the lack of prospective clinical … Among the studies we identified, we found a general lack of well-designed, well-controlled studies, … The general lack of data hampered our evaluation of systemic and local antimicrobial therapy, and we … The lack of strong evidence may impact reimbursement for various modalities.

158. Disposition of Comments for CER 158 Diagnosis of Gout (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/gout-diagnosis-disposition-160727.pdf
     February 24, 2016 - The lack of validation was noted. … classification and tests for clinical diagnosis in the draft report seems to have arisen from the lack … would be much more digestible and useful if the evidence supporting each diagnostic test (or the lack … The lack of stratification could affect both, not one more than the other. … Given the lack of sufficient data, policy and practice decisions are unlikely to be altered.

159. 8 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-harms_methods.pdf
     November 01, 2008 - First, most RCTs lack prespecified hypotheses for harms. 5 Rather, hypotheses are usually designed … insufficient to assess the methods used to select participants. 45 In addition, because such studies lack … , tolerated the medication, and agreed to participate in the extension), are unblinded, and often lack … Observational Studies Because observational studies lack randomization, they should adhere to high … In such cases, CERs should acknowledge the lack of statistical power to assess risk adequately and

160. Research White Paper: A Framework To Facilitate the Use of Systematic Reviews and Meta-analyses in the Design of Primary Research Studies (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/primary-research-design_research.pdf
     January 01, 2012 - First, research questions posed may lack relevance to clinicians and patients. … Adequately implies an effect size which demonstrates evidence of effect (or lack of effect), an effect … Other considerations: Although strength (or lack of strength) of evidence existing is the most important … Imprecise data: insufficient evidence of effect or lack of effect 3. … proposed framework attempts to address some of these potential reasons—namely that researchers may lack