-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/medication-therapy-management_executive.pdf
November 01, 2014 - about the lack of
convincing evidence on benefit, harm, or lack of effect. … limitations,
inconsistent, direct, imprecise
Inconsistent direction of
effect but consistent in lack … Study limitations,
lack of consistency, and lack of precision of the estimates
of effects limited the … KQ 5: Harms of MTM Interventions
Lack of precision and the limitations of a single study with
high … described
below, the evidence led us to conclude with a low strength
of evidence either a benefit or lack
-
effectivehealthcare.ahrq.gov/sites/default/files/technical-brief-36-patient-engagement-comments.pdf
August 26, 2020 - criteria for the lit
reviews was similarly effective, though, as mentioned before,
hamstrung by the lack … Related to the studies and lack of harm reported. … The authors
emphasize the lack of research on health system and
community strategies. … So this shows a clear lack of understanding of the
measurement area. … Public reviewer #12:
National Center for Health
Research (NCHR)
General The Brief notes a lack of
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/menopause_disposition-comments.pdf
March 05, 2015 - The attention to the
important problem of the widespread use of compounded hormones
and the lack of … We have added text in appropriate places regarding
lack of applicability to breast cancer survivors … Their focus on
the lack of evidence on compounded HT (safety and efficacy) being
used by millions of … Text has been added to the discussion noting the
lack of applicability to women with primary ovarian … The clear consistency and estimate
precision support the lack of downgrading.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-cancer_clinician.pdf
July 01, 2017 - biopsied mass
�– The significant heterogeneity in tumor characteristics
observed in renal tumors
�– The lack … of a standardized biopsy protocol
�– Weak study designs (e.g., retrospective studies)
�– The lack of … ��The lack of sufficient data comparing active surveillance with
other treatment approaches limits the
-
effectivehealthcare.ahrq.gov/sites/default/files/developmental-delays-horizon-scan-high-impact-1306.pdf
June 01, 2013 - including attention-deficit hyperactivity disorder and autism spectrum
disorders (ASDs) implies a lack … and health outcomes: Experts agreed the unmet need for this intervention is
significant; they cited lack
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/pelvic-pain_executive.pdf
January 01, 2012 - two RCTs, one of fair and one of
poor quality, we assessed the strength of evidence as
low for the lack … This lack of
placebo comparison detracts from the active head-to-
head trials because no initial validation … Lack of direct comparisons of treatment options further
hinders our ability to know what findings will … The literature overall is muddled by a lack of
standardized definitions for CPP and unclear diagnostic … reviews of the effectiveness of interventions
for a symptom or syndrome are fraught with difficulty;
the lack
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-275-people-with-disabilities-disposition-comments.pdf
September 16, 2024 - The lack of inclusion of stroke is also
notable. … Peer Reviewer
#1
Results Table 9: Lack of sedation during breast cancer
screening? … The lack of funding is the primary reason we
have such limited studies and data. … of the limited scope of the review, the
discussion clearly states that their has been a relative
lack … However, some impression gained by the reviewers on
the consistency (or lack of consistency) across
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-evidence-communication_executive.pdf
November 01, 2013 - Given the lack of prior reviews related to communicating
uncertainty, we searched from January 1, 1966 … They
attributed the lack of differential impact to a possible
“ceiling effect” in the study population … We
saw this lack of consensus across studies especially for
defnitions of three key terms: dissemination … With respect
to KQ 2, the lack of consistency in how dissemination
strategies are referenced and classifed
-
effectivehealthcare.ahrq.gov/sites/default/files/antipsychotics-children-update-disposition-170621.pdf
March 16, 2017 - It was good to mention the lack of evidence
for use in other mental health conditions and the lack … Mentioning the lack of clinically meaningful difference
and what degrees of change suggested them beyond … The most notable shortcoming was the
lack of a detailed description of the meta-analytic
models. … We have added a definition of what
we considered a nonrandomized trial; only
difference may be lack … The lack of evidence is
concerning.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-children-update-disposition-170621.pdf
March 16, 2017 - It was good to mention the lack of evidence
for use in other mental health conditions and the lack … Mentioning the lack of clinically meaningful difference
and what degrees of change suggested them beyond … The most notable shortcoming was the
lack of a detailed description of the meta-analytic
models. … We have added a definition of what
we considered a nonrandomized trial; only
difference may be lack … The lack of evidence is
concerning.
-
effectivehealthcare.ahrq.gov/sites/default/files/home-based-care_disposition-comments.pdf
February 16, 2016 - Thank you, we agree that the lack of
literature is a challenge and have
emphasized the need for more … A serious gap is the lack of any qualitative data, which could
have been accomplished with relative … The Hughes study
also suffered from tremendous lack of fidelity.
Thank you. … It is certainly appropriate to say that we may lack
the highest quality evidence. … Given the lack of evidence in the review, the need
for further research in this area
should simply
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cesarean-birth-2010_disposition-comments.pdf
January 01, 2010 - However, in the executive summary and other
summaries throughout, there is lack of attention to the … With rates much lower than the current US rates of
concern, how are we to interpret a lack of effect … The issue of lack of power to detect harm should be
highlighted and discussed in more detail. … Page 81: We have added notes on the lack of approval of
the vehicle in the US so that it is noted in … TEP #3 Clarity & Usability The phrase "low strength of evidence for lack of benefit,"
which appears
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/models-care-adult-survivors-childhood-cancer-evidence-summary.pdf
February 01, 2022 - There is
also a lack of clarity about which models are appropriate for whom and in what circumstances … There was a lack of formal evaluations of
models of care and data on final outcomes, particularly mortality
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-257-antenatal-care-disposition-comments.pdf
June 28, 2022 - • One reviewer commented on the lack of evidence pertaining to underrepresented
groups. … have better
summarized
the applicability
in the
Discussion and
more explicitly
highlighted the
lack
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-276-ocd-executive-summary.pdf
December 01, 2024 - However, we found a
consistent lack of association with treatment response for age (7 studies), sex … For post-treatment CY-BOCS score, we found
a consistent lack of association for age (6 studies), sex
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-272-genitourinary-syndrome-disposition-comments.pdf
July 31, 2024 - • Several peer reviewers requested more attention to the implications of lack of long-
term data … , TX
General I question the data surrounding the breadth of
US-available interventions given the lack
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-decision-support-tools_disposition-comments.pdf
December 23, 2014 - Do
you think the lack of difference in format is because there was double
counting (if there was) or … Due
to the considerable length of the review and
lack of space, we provide the detailed
analysis plan … ”: Meta-regression analyses are typically
inadequate powered – is this a potential reason for the lack … TEP Reviewer #3 Clarity and
Usability
Page 23, last paragraph: you lack bullet point Fixed. … Yet,
KQ2 was a priori defined and we chose to
show the observed lack of evidence.
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-242-radiation-therapy-brain-metastases-disposition-comments.pdf
June 09, 2021 - 2021
4
Commentator
& Affiliation
Section Comment Response
TEP #5 General Questions: The lack … of nuance in the key
questions leads to lack of nuance and value in
the recommendations and conclusions … TEP #7 General Use of terminology likely “concrete” effect
estimate seems to lack scientific rigor and … Peer
Reviewer #2
Evidence
Summary
The comments on lack of effect of CNS therapies
on overall survival … The
data were reported similarly, but
lack of mean and standard
deviation prevented combining
these
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0122_06-29-2009.pdf
January 01, 2009 - Effective Health Care
Topic Number: 0163
Document Completion Date: 6-7-10
1
Results of Topic Selection Process & Next Steps
Nitrous oxide for the management of labor pain will go forward for refinement as a systematic review.
The scope of this topic, including populations, interventions, co…
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/undescended-testicle_executive.pdf
December 01, 2012 - Clinical uncertainty and lack of guidance exist on
the appropriate clinical pathway for treatment of … Overall,
only eight good-quality studies were available for analysis,
and this lack of good-quality … The lack of
good-quality studies affects our degree of confidence in
establishing a rate of prediction … Although retrospective studies typically have high risk
of bias because of lack of a control group,