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Total Results: 1,324 records

Showing results for "lack".

101. Disposition of Comments for Local Nonsurgical Therapies for Stage I and Symptomatic Obstructive Non-Small-Cell Lung Cancer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/lung-cancer-nonsurgical-therapies_disposition-comments.pdf
     June 12, 2013 - There is a lack of analysis for RFA of medically inoperable stage I NSCLC. … This analysis should be helpful to physicians to allow more meaningful discussion about the lack of … We agree, the clinical value of the report indeed may be restricted because of a lack of robust comparative … Commentator & Affiliation Section Comment Response Reviewer 8 (TEP) General Comment Given the lack … of evidence does not necessarily translate to lack of effectiveness and this should be stressed.

102. Venous Thromboembolism Prophylaxis in Major Orthopedic Surgery: Systematic Review Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/thromboembolism-update-disposition.pdf
     June 22, 2017 - The lack of comparative evidence regarding aspirin resulted in a lack of evidence-based conclusions … of clinically meaningful outcomes, and the lack of appropriate comparisons. … The lack of evidence about most outcomes is problematic, as discussed. … The lack of comparison between the two drugs for KQ 5 related to total hip replacement. … We understand the concerns about the lack of direct comparative studies on aspirin.

103. Effective Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0404_01-14-2011.pdf
     January 01, 2011 - approval of vasodilator medications for PAH over the past 3 decades; however, there continues to be a lack

104. Moyer_ECCS2012 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/moyer_eccs2012.pdf
     January 01, 2012 - Slide 9: The Mammography Firestorm: Lack of Awareness • At its creation in 1984, the U.S.

105. REQUEST FOR TASK ORDER (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-end-of-life-quality-meaures_research.pdf
     April 01, 2010 - chemotherapy (6a), the receipt of opiates (6b), the occurrence of chemotherapy toxicity (6c), and lack … and the occurrence of chemotherapy toxicity (prospective only, but was negatively associated with lack … retrospective), more likely to have chemotherapy toxicity (prospective only), and more likely to lack … Linkage to other data sources, for example the National Death Index, could make up for a lack of this … The lack of effect of market structure on hospice use.

106. Multiple-Sclerosis Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/multiple-sclerosis_executive.pdf
     April 01, 2015 - results as a surrogate marker for relapse rates or, more importantly, disease progression, currently lack … Dropouts from observational studies are more likely to bias reporting toward lack of adverse events … discontinuation based both on clinician evaluation of disease progression and patient evaluation of lack … differential effectiveness of DMTs for different patient subpopulations is unclear because of the lack … Is the lack of relapses due to ongoing DMT use, or has this patient’s MS reached the stage where the

107. Disposition of Comments for Treatments for Fibromyalgia in Adult Subgroups (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/fibromyalgia_disposition-comments.pdf
     January 26, 2015 - Psychological studies were high risk of bias for a number of reasons, not just inability or lack of … very few non-pharmacologic studies qualified for the review, but suspect that this is due to the lack … The lack of good data makes it impossible to come to any strong conclusions. … I am not sure that the lack of evidence shown in this review will inform policy or practice decisions … Lack of data is just that, a lack of data, it does not warrant making any conclusions about any of

108. Disposition of Comments_Models of Care That Include Primary Care for Adult Survivors of Childhood Cancer: A Realist View (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/childhood-cancer-disposition-comments.pdf
     February 16, 2022 - I am not sure if my relative "underwhelm" is due to the lack of evidence in this field or the lack … this study differs from a systematic review though it is implied that this is because there is a lack … Conclusions Implications of discussions are adequate and limitations are discussed (namely the lack … We do however note in the Discussion the lack of evidence regarding final outcomes, such as mortality … The report also found a lack of formal evaluations of outcome data for the models of care, particularly

109. Ankyloglossia Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ankyloglossia_executive.pdf
     May 01, 2015 - studies used different populations and measured different outcomes. 9 Speech Outcomes Given the lack … Imprecise Undetected Insufficient SOE for all feeding outcomes, given small number of participants, lack … Lack of a consistent objective measure to define and classify this condition may limit the reproducibility … In particular, there is a lack of evidence on significant long-term outcomes, such as exclusive breastfeeding … The field is currently challenged by a lack of standardized approaches to assessing and studying the

110. PULMONARY with "Discussions" in Exec Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pulmonary_hi_impact.pdf
     April 01, 2012 - However, experts also cited the small evidence base, lack of long-term data, serious risks associated … However, the experts cited the small evidence base, lack of long-term data, serious adverse events … reported, required investment in equipment and training, and lack of qualified bronchoscopists as … efficacy results, experts were concerned about the initial worsening of symptoms after BT and the lack … However, the experts cited the small evidence base, lack of long-term data, serious risks associated

111. Future Research Needs for Attention Deficit Hyperactivity Disorder: Effectiveness of Treatment in At-Risk Preschoolers, Long-Term Effectiveness in All Ages, and Variability in Prevalence, Diagnosis, and Treatment (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/adhd-future_research.pdf
     May 01, 2012 - KQ 1 Among people less than 6 years of age with disruptive behavior disorder or ADHD, there is a lack … KQ 2 Among people ages 6 years or older with ADHD, there is a lack of high-quality studies on efficacy … KQ 2 For people ages 6 years or older, there is a lack of evidence to support standardized methods … KQ 1 Among people less than 6 years of age with disruptive behavior disorder or ADHD, there is a lack … KQ 2 For people ages 6 years or older, there is a lack of evidence to support standardized methods

112. Biomarkers for Assessing and Managing Iron Deficiency Anemia in Late-Stage Chronic Kidney Disease: Future Research Needs (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-kidney-disease-anemia_research.pdf
     January 01, 2013 - Outcomes: • There is a lack of a generally accepted reference standard test for determining iron … treatment. 1 Study Design Issues: • Many existing studies are at a high risk of bias due to lack … • There are a lack of studies with longer followup durations; existing short- term RCTs had a followup … Not rated (descriptive data) • There is a lack of generally accepted reference standard tests for … Outcomes: • There is a lack of a generally accepted reference standard test for determining iron

113. Disposition of Comments Report for Cardiac Troponins Used as Diagnostic and Prognostic Tests in Patients Wtih Kidney Disease (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-function_disposition-comments.pdf
     August 11, 2014 - We decided to keep the meta- analysis figures sorted by cutpoints but mentioned the lack of temporal … Peer reviewer #3 Results The results highlight the lack of quality evidence to answer the research questions … We discussed the lack of temporal trends in the report text. … TEP #2 Executive Summary Page1,Troponin Detection in Normal And Disease states-There may be some lack … issues with troponin which make the studies difficult to interpret or draw conclusions from such as lack

114. Disposition of Comments for Pressure Ulcer Treatment Strategies: Comparative Effectiveness (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/pressure-ulcer-treatment_disposition-comments.pdf
     May 08, 2013 - Reviewer: 3 General/Overall Comments Overall concerns: Lack of discussion on repositioning: In reading … If there is no literature on repositioning, than the report should reflect this lack of information … Reviewer: 7 General/Overall Comments The report is very useful and particularly points out the lack … Also, it was useful to have clarity brought to the issue of a lack of common outcome data sets and … The review reinforces there is a lack of well- designed studies to provide a high level of evidence

115. Disposition of Comments for Interventions for Adolescents and Young Adults With Autism Spectrum Disorders (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/autism-adolescents_disposition-comments.pdf
     August 27, 2012 - We have been careful to emphasize that there is a lack of current research in a new and growing field … #3 Discussion/con clusions [Additional detail for discussion section] Another barrier may be the lack … TEP #2 General The abstract should emphasize the need for evidence and lack of funding for developing … Also notes the relative lack of attention to older adolescents and adults with ASDs. … This is due, in part, to the lack of information on assessment of adherence.

116. Disposition of Comments Report for Treatment of Depression During Pregnancy and the Postpartum Period (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-pregnancy-postpartum_disposition-comments.pdf
     July 08, 2014 - impression is that this is not one of AHRQ’s stronger reports but a large part of this lies with the lack … ), but also however on the lack of heterogeneity of studied populations (i.e. socioeconomic status, … Because of the lack of evidence, the conclusions cannot inform policy or practice decisions. … Additionally, the lack of direct evidence makes finding true conclusions (other than the lack thereof … answers) found in the literature are summarized in a way that identifies the lack of evidence for

117. Management of Uterine Fibroids - Evidence Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/evidence-summary-cer-195-uterine-fibroids-final.pdf
     December 01, 2017 - reviews served to answer key questions about epidemiologic correlates of fibroids, to demonstrate lack … outcome of interest reported); however, the single available trial was of poor quality including lack … The other studies were rated as poor quality primarily due to lack of masking participants and outcome … Lack of precision means these estimates are not credibly different. … Lastly, the lack of direct comparisons limits the information this can provide to help a woman or her

118. Disposition of Comments Report for Imaging Techniques for the Diagnosis and Staging of Hepatocellular Carcinoma (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/liver-cancer_disposition-comments.pdf
     October 23, 2014 - Given the lack of high quality randomized data to support screening/surveillance for HCC in high risk … The evidence (or lack thereof) showing effects of screening on clinical outcomes is presented in the … need to make their own judgments about the value of the often limited evidence (and almost complete lack … generated by a combination of unsuitable underlying study designs and more importantly a general lack … of the ultimate observations and responses to the key questions are held hostage to the quality (or lack

119. Evidence Summary - Comparative Effectiveness Review No. 249: Malnutrition in Hospitalized Adults: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-249-malnutrition-hospitalized-adults-evidence-summary_0.pdf
     October 01, 2021 - These limitations, along with inconsistencies in the findings for some outcomes and lack of precision

120. Evidence Summary - Comparative Effectiveness Review No. 249: Malnutrition in Hospitalized Adults: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-249-malnutrition-hospitalized-adults-evidence-summary.pdf
     October 01, 2021 - These limitations, along with inconsistencies in the findings for some outcomes and lack of precision