-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-209-evidence-summary-non-pharma-chronic-pain.pdf
June 01, 2018 - – Knee osteoarthritis: Exercise,
ultrasound.
– Hip osteoarthritis: Exercise, manual
therapies. … chronic pain
conditions:
KQ 1: Chronic low back pain
KQ 2: Chronic neck pain
KQ 3: Osteoarthritis (knee … Comparative Effectiveness of Interventions for
Osteoarthritis
• Knee Osteoarthritis: One trial of pain … Osteoarthritis of the knee: effects of nonpharmacological interventions compared with exercise
Table … Treatment of
Osteoarthritis of the Knee: An Update Review.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-f2-surv-report-3-nonopioid-pharmacol-chronic-pain.xlsx
May 29, 2025 - 12 Short 2 33 0 33 NR NR NR NR NR NR NR NR 1 33 33 NR NR NR NR NR NR NR 0 33 33
Hudson, 2021 Good Knee … NR 4 99 NR NR NR NR NR NR NR NR 86 99 102 Sweating 31 99 102 58 99 102 NR NR NR
Hudson, 2021 Good Knee
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoarthritis-pain_research-protocol.pdf
August 05, 2010 - life.2 About 6 percent of U.S. adults aged 30 years or older have
symptomatic osteoarthritis of the knee … Pennsaid®)
Labeled indications Dosing Dose adjustments for special
populations
Osteoarthritis of knee … 40 drops on each
painful knee,
4x/day
Patients with fluid retention or heart
failure: use with … Incidence of
symptomatic hand, hip, and knee osteoarthritis among patients in a health
maintenance … An update on the epidemiology of knee and hip
osteoarthritis with a view to prevention.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-2023-update-surv-rep-3.pdf
January 01, 2023 - Oral
cannabidiol (CBD) as add-on to paracetamol for
painful chronic osteoarthritis of the knee: a
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/opioid-chronic-pain-surveillance-report-3.pdf
June 01, 2022 - new trial4 compared transcutaneous electrical nerve stimulation (TENS)
versus opioids for chronic knee … Reduction of Opioids Prescribed Upon
Discharge After Total Knee Arthroplasty
Significantly Reduces … Is
There Any Role for Opioids in the
Management of Knee and Hip
Osteoarthritis? … Influence of inpatient opioid consumption
on persistent use following total knee
arthroplasty. … Risk of
chronic opioid use after simultaneous versus
staged bilateral knee arthroplasty.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoporosis-vibration-therapy_technical-brief.pdf
January 01, 2020 - Further, since vibration transmissibility to the head and trunk can be altered by knee flexion and
posture … Compliance, nutritional intake, location of therapy,
posture/knee flexion, whether dynamic exercises … All
were instructed to take 800 mg
of calcium daily in food
Patients with osteoarthritis of
the knee … diseases other than
osteoporosis that cause back
pain; Patients who had
undergone arthroplasty of the
knee … pain in 2
overweight
participants with
preexisting knee
osteoarthritis
Iwamoto, 200531 Not reported
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-2023-surv-rep-4.pdf
January 01, 2023 - Oral
cannabidiol (CBD) as add-on to paracetamol for painful
chronic osteoarthritis of the knee: a randomized
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/thromboembolism-update-executive-170622.pdf
June 01, 2017 - DVT) and pulmonary embolism (PE).1
The major orthopedic surgeries of greatest
concern include total knee … Assess venous thromboembolism
(VTE) prevention interventions with
total hip replacement (THR), total knee … KQ 2 update of original KQ 6): In patients undergoing
major orthopedic surgery (total hip or knee … KQ 5 (new KQ): In patients undergoing major
orthopedic surgery (total hip or knee
replacement, hip … KQ 6 (new KQ): In patients undergoing major
orthopedic surgery (total hip or knee
replacement, hip
-
effectivehealthcare.ahrq.gov/sites/default/files/thromboembolism-update-executive-170622.pdf
June 01, 2017 - DVT) and pulmonary embolism (PE).1
The major orthopedic surgeries of greatest
concern include total knee … Assess venous thromboembolism
(VTE) prevention interventions with
total hip replacement (THR), total knee … KQ 2 update of original KQ 6): In patients undergoing
major orthopedic surgery (total hip or knee … KQ 5 (new KQ): In patients undergoing major
orthopedic surgery (total hip or knee
replacement, hip … KQ 6 (new KQ): In patients undergoing major
orthopedic surgery (total hip or knee
replacement, hip
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-opioid-chronic-pain-surveillance-report-3.xlsx
September 30, 2015 - 12 weeks; optional 12 week followup
Multicenter
France Pain condition: Chronic moderate to severe knee … to the neurostimulation method for the treatment of moderate to severe chronic nociceptive pain in knee … low back pain
Age: ≥18 years
Pain severity: mean ≥5 on NRS pain scale
Exclusions: Patients with hip/knee … Pain condition: Moderate to severe osteoarthritis pain of the hip or knee
Age: NR
Pain severity: WOMAC … without adequate pain relief, medication was not tolerated, or patient was a
candidate for total hip or knee
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-e-surv-report-2-nonopioid-pharmacol-chronic-pain.xlsx
May 29, 2025 - N Randomized
N Analyzed Intervention Duration (Weeks) Funding Source
Hudson, 2021
New Zealand
Good Knee
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-chapter-4.pdf
July 01, 2019 - Patellar resurfacing in total knee arthroplasty. A meta-analysis. … Patellar Resurfacing in Total Knee Arthroplasty for Pain
RE = random effects model
https://doi.org/ … Patellar resurfacing in total knee arthroplasty. A meta-analysis.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/opioid-chronic-pain-surveillance-report-2.pdf
April 01, 2022 - Reduction of Opioids Prescribed Upon
Discharge After Total Knee Arthroplasty
Significantly Reduces … Effectiveness and safety of non-steroidal
anti-inflammatory drugs and opioid
treatment for knee and … Is
There Any Role for Opioids in the
Management of Knee and Hip
Osteoarthritis? … Influence of inpatient opioid consumption
on persistent use following total knee
arthroplasty. … Risk of
chronic opioid use after simultaneous versus
staged bilateral knee arthroplasty.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-f1-surv-report-1-nonopioid-pharmacol-chronic-pain.xlsx
May 29, 2025 - Variance Between-Group Change Lower Limit Between-Group Change Upper Limit p-Value
Hudson, 2021 Good Knee … Variance Between-Group Change Lower Limit Between-Group Change Upper Limit p-Value
Hudson, 2021 Good Knee … Variance Between-Group Change Lower Limit Between-Group Change Upper Limit p-Value
Hudson, 2021 Good Knee … NR NR 102 103 Baseline-adjusted difference at endpoint 2 95% CI NR -0.39 4.43 0.1
Hudson, 2021 Good Knee
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/opioids-chronic-pain-surveillance-report-1-final.pdf
April 01, 2022 - Opioid
users show worse baseline knee
osteoarthritis and faster progression of
degenerative changes … Reduction of Opioids Prescribed Upon
Discharge After Total Knee Arthroplasty
Significantly Reduces … Is
There Any Role for Opioids in the
Management of Knee and Hip
Osteoarthritis? … Influence of inpatient opioid consumption
on persistent use following total knee
arthroplasty. … Risk of
chronic opioid use after simultaneous versus
staged bilateral knee arthroplasty.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/point-of-care_research.pdf
April 01, 2014 - Physical Therapy Interventions for Knee
Pain Secondary to Osteoarthritis. … Physical therapy interventions for knee pain
secondary to osteoarthritis: a systematic review. … Physical Therapy
Interventions for Knee Pain Secondary to Osteoarthritis. … Physical therapy
interventions for knee pain secondary to osteoarthritis: a systematic
review. … Physical Therapy
Interventions for Knee Pain Secondary to Osteoarthritis.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-2025-surv-rep-update-executive-sum.pdf
January 01, 2025 - were placebo-
controlled—one evaluated plant-derived topical hemp seed oil or diclofenac 1% gel
for knee … One (n=90) compared plant-derived
topical hemp seed oil or diclofenac 1% gel versus placebo for knee … Seed Oil on Knee Osteoarthritis: A
Randomized Double-Blind Controlled Trial.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-f1-surv-report-3-nonopioid-pharmacol-chronic-pain.xlsx
May 29, 2025 - Variance Between-Group Change Lower Limit Between-Group Change Upper Limit p-Value
Hudson, 2021 Good Knee … 103 Baseline-adjusted difference at endpoint -6.2 95% CI NR -0.26 12.56 0.06
Khan Panezai, 2021 Fair Knee … Variance Between-Group Change Lower Limit Between-Group Change Upper Limit p-Value
Hudson, 2021 Good Knee … Variance Between-Group Change Lower Limit Between-Group Change Upper Limit p-Value
Hudson, 2021 Good Knee … NR NR 102 103 Baseline-adjusted difference at endpoint 2 95% CI NR -0.39 4.43 0.1
Hudson, 2021 Good Knee
-
effectivehealthcare.ahrq.gov/sites/default/files/communicating_risk_international_king.ppt
January 01, 2005 - Acute Musculoskeletal Pain
Low Back Pain
Thoracic Spinal Pain
Neck Pain
Shoulder Pain
Anterior Knee
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-f1-surv-report-2-nonopioid-pharmacol-chronic-pain.xlsx
May 29, 2025 - Variance Between-Group Change Lower Limit Between-Group Change Upper Limit p-Value
Hudson, 2021 Good Knee … Variance Between-Group Change Lower Limit Between-Group Change Upper Limit p-Value
Hudson, 2021 Good Knee … Variance Between-Group Change Lower Limit Between-Group Change Upper Limit p-Value
Hudson, 2021 Good Knee … NR NR 102 103 Baseline-adjusted difference at endpoint 2 95% CI NR -0.39 4.43 0.1
Hudson, 2021 Good Knee