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Showing results for "issues".

461. Disposition of Comments for CER 183 Tonsillectomy for OSDB (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/tonsillectomy-disposition-170415.pdf
     January 17, 2017 - Affiliation Section Comment Response Peer reviewer #2 Introduction Introduction: Appropriate - no issues … We have revised the Introduction and Discussion to include more detail about issues of characterizing … TEP reviewer #3 Results KQ6 (ES-12-13): this section is short and does not address the clinical issues … Comment Response Peer reviewer #2 Discussion Discussion/ Conclusion: Discussion hits on important issues … We have revised the Research Gaps section to comment more directly on issues we identified in the review

462. Disposition of Comments: Comparative Effectiveness Review No. 232_Interventions for Breathlessness in Patients With Advanced Cancer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-232-breathlessness-cancer-comments.pdf
     November 19, 2020 - paucity of high quality studies, combining studies with very different interventions/designs, and some issues … We have also added to the discussion issues about these older studies conducted in a time when there … We have added the issues of pilot trials and study targets. 2. … Regardless, it was difficult to conclude much about side effects given reporting issues. … I will confine my comments to 2 issues: Scope of non pharmacologic interventions and the section on

463. Asthma-Treatment Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/asthma-treatment_executive.pdf
     May 01, 2011 - The TEP provided comments on the methods protocol and provided input on substantive issues such as … N=2 Not one of the specified study designs: N=7 High or differential attrition: N=1 Other quality issues … Two of the India-based trials were among the group with fairly substantial methodological issues.31,34 … All but one38 had substantial quality issues. … symptoms in three trials of intensive yoga breathing training conducted in India.31,34,35 Quality issues

464. Crosscutting-Horizon-Scan-High-Impact-1312 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/crosscutting-horizon-scan-high-impact-1312.pdf
     December 01, 2013 - Experts thought that such insight might enable clinicians to explore with patients issues that the … These issues are believed to affect the conduct and analyses of trial results.2 Technologies are needed … expert mentioned that about 50% of patients with chronic diseases experience prescription adherence issues … delivery innovation, perceiving it as competition and highlighting concerns of misdiagnosis and issues … Promoting effective transitions of care at hospital discharge: a review of key issues for hospitalists

465. Trauma-Interventions-Maltreatment-Child Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/trauma-interventions-maltreatment-child_executive.pdf
     April 01, 2013 - We did not conduct a quantitative meta-analysis because of issues related to heterogeneity, insufficient … and challenging-to-serve families; that is, maltreated children whose parents were struggling with issues … For feasibility issues, such families were commonly excluded from a study sample. … Beyond these particular statistical issues, a more fundamental question that merits increased attention … J Soc Issues. 2006;62(4):767-85. PMID: ISI:000241562500006. 33.

466. Discerning the Perception and Impact of Patients Involved in Evidence-based Practice Center Key Informant Interviews (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/key-informant-interviews-research.pdf
     December 19, 2017 - reports, AHRQ supports empiric research by the EPCs to help understand or improve complex methodologic issues … Prior to the focus group discussion, the KIs were sent a summary of the key issues that came out of … The summary of key issues that was created following the individual interviews and focus group discussion … of the things they gave us was called ‘Considerations for Key Informants,’ which were questions and issues … Prior to today’s discussion, we sent out a summary of the key issues that came out of the individual

467. Assessing the Risk of Bias of Individual Studies in Systematic Reviews of Health Care Interventions (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-bias-individual-studies_methods.pdf
     March 01, 2012 - This Guide presents issues key to the development of Comparative Effectiveness Reviews and describes … recommended approaches for addressing difficult, frequently encountered methodological issues. … conflict of interest, to rate a study as high risk of bias, although reviewers should report these issues … Quasi- experimentation: design and analysis issues for field settings. … The Handbook emphasizes that topics within the other domain should focus on issues related to bias

468. Disposition of Comments Report for Medication Adherence Interventions: Comparative Effectiveness (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/medication-adherence-interventions_disposition-comments.pdf
     September 11, 2012 - Peer Reviewer #4 Executive Summary Other than its length, several other issues with the Executive … I may not have identified all of these issues but I was distracted by things like depression care covered … Summary is 20 pages long – requiring far more time than someone wishing to gain a quick overview of the issues

469. Disposition of Comments Report for Multigene Panels in Prostate Cancer Risk Assessment (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer-risk-assessment-genes_disposition-comments.pdf
     July 03, 2012 - The three key questions cover well the issues at stake and to be resolved, and they are clearly stated

470. Disposition of Comments Report for Local Hepatic Therapies for Metastases to the Liver From Unresectable Colorectal Cancer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-cancer-liver-metastases-therapies_disposition-comments.pdf
     December 11, 2012 - This report is critical since it clearly outlines the issues, provides an extensive review of the literature … These issues should be addressed somewhere in the review. Thank you. … Thank you Peer Reviewer #8 Introduction The authors do a reasonable job at introducing the topic and issues … A registry will not advance the critical issues that need to be answered through high quality scientific

471. Development of a Primary Care Guie for Implementing Evidence-Based Screening and Counseling for Unhealthy Alcohol Use With Epic-Based Electronic Health Record Tools: A Pilot Dissemination Project (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-research-report-unhealthy-alcohol-use-final.pdf
     September 01, 2018 - reports, AHRQ supports empiric research by the EPCs to help understand or improve complex methodologic issues … Suggestions for improvement focused on issues of clarity and organization, as well as making the package … Suggestions from KIs about how to improve the package focused on issues of clarity and organization … If we were to implement this package elsewhere, what are the most important issues to keep in mind?

472. Meditation Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/meditation_research-protocol.pdf
     October 17, 2012 - Due to issues of scope, and to ensure consistency with the nomination, our review will largely focus … In a situation where double blinding may not be feasible, the burden of the design issues is higher … We will evaluate the selection process of these studies to determine such issues around applicability … information to the EPC to identify literature search strategies and recommend approaches to specific issues

473. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/atypical-antipsychotics-off-label-update_disposition-comments.pdf
     September 01, 2011 - We have tried our best to highlight the evidence and the issues, but recognize it is not the role … 13 Reviewer Comment Section Page Comment Response BMS Executive Summary - Remaining Issues … ES- 14 In the “remaining issues” section on page 14, it is mentioned that “It would facilitate … Treatment and prescribing issues are complicated.

474. Methods Guide for Medical Test Reviews (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-metaanalysis_methods.pdf
     July 01, 2012 - These framing issues are addressed in other chapters of this Medical Test Methods Guide.6–8 Further, … Syntheses of medical test data often focus on test performance, and much of the attention to statistical issues … expected that readers are versed in clinical research methodology and familiar with methodological issues … We will expand on some of these issues. 8-4 Figure 8–1a.

475. pneumonia-antibiotic-treatment-protocol-130718 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/pneumonia-antibiotic-treatment_research-protocol.pdf
     July 19, 2013 - www.effectivehealthcare.ahrq.gov Published online: July 19, 2013 5 In their consensus document on controversial issues … study assessed as having high risk of bias has significant risk of bias (e.g., stemming from serious issues … Consensus document on controversial issues for the treatment of hospital- associated pneumonia. … information to the EPC to identify literature search strategies and recommend approaches to specific issues

476. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/rheumatoid-arthritis-2007_executive.pdf
     January 01, 2007 - All the same issues noted for RA of short- and long-term risks and safety, as well as performance in … Remaining Issues Most of the trials were conducted in RA patients; data are limited for PsA patients. … Issues similar to those for RA with respect to long-term outcomes and early initiation are also important

477. Nephropathy-Contrast-Induced Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/nephropathy-contrast-induced_executive.pdf
     October 01, 2015 - this conclusion; one study included only patients with CKD, two included only patients with cardiac issues … Two studies included only CKD patients, one included patients with cardiac issues, and one had a general … Recent issues in contrast- induced nephropathy. Int J Urol. 2011 Oct;18(10):686-90.

478. S16 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/s16.pdf
     October 01, 2007 - from industry-funded trials may remain unpublished, limiting the ability to examine potential safety issues … Subgroup analysis within trials can help explore impor- tant issues of heterogeneity of treatment effect15 … Considering usual medical care in clinical trial design: scientific and ethical issues.

479. Pharmacologic Management of Acute Pain by EMS in the Prehospital Setting Protocol Amendment (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/acute-pain-ems-protocol-amendment.pdf
     January 28, 2019 - current review. 2 In addition to the effectiveness and harms of prehospital analgesia, issues … Potential issues include direct harms of prehospital analgesia to the EMS provider themselves. … information to the EPC to identify literature search strategies and suggest approaches to specific issues

480. Slide 1
     effectivehealthcare.ahrq.gov/sites/default/files/comparator-selection-in-observational-chapter-5.pptx
     January 01, 2013 - , the use of a historical control needs to be justified after considering associated methodological issues … in observed and unobserved domains as they are sampled differently or different source populations Issues … On the other hand, implantable devices or surgical procedures do not generally have adherence issues