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  1. effectivehealthcare.ahrq.gov/sites/default/files/pdf/wireless-motility-capsule-future_research.pdf
    May 01, 2013 - reviewed by the stakeholder panel in two lists to allow them to comment, suggest and rank important issues … for both the directly important clinical issues, and the foundational and methodological questions. … reviewed by the stakeholder panel in two lists to allow them to comment, suggest and rank important issues … for both the directly important clinical issues, and the foundational and methodological questions. … for both the directly important clinical issues for WMC and the methodological questions.
  2. 13-MDM347013 30..38 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/pdf/outcomes-testing-evaluation_research.pdf
    January 01, 2009 - relationships and feelings of guilt about passing on the faulty gene to their offspring.24 Similar issues … offered testing but decline.30 Other reported additional effects of testing include legal and ethical issues … measures rarely capture all the possible effects of testing discussed here, and they may miss other issues … Prenatal screening and diagnosis of congenital toxoplasmosis: a review of safety issues and psychological
  3. effectivehealthcare.ahrq.gov/sites/default/files/pdf/long-term-care-adults_research-protocol.pdf
    December 20, 2011 - Even still, measurement issues further confound the effort to compare case mixes between institutions … Issues related to service delivery and financing mechanisms are central to LTC policy, and policymakers … interdisciplinary index of the literature on aging with exclusive focus on older adults (>50) and aging related issues … information to the EPC to identify literature search strategies and recommend approaches to specific issues
  4. 13-MDM347013 30..38 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/whitepaper4-bossuyt02262010-2.pdf
    January 01, 2009 - relationships and feelings of guilt about passing on the faulty gene to their offspring.24 Similar issues … offered testing but decline.30 Other reported additional effects of testing include legal and ethical issues … measures rarely capture all the possible effects of testing discussed here, and they may miss other issues … Prenatal screening and diagnosis of congenital toxoplasmosis: a review of safety issues and psychological
  5. effectivehealthcare.ahrq.gov/sites/default/files/pdf/nppv-respiratory-failure_research-protocol.pdf
    April 21, 2011 - preventing reintubation is for patients with COPD or hypercapnia. 14-19 Controversy and Policy Issues … peer-reviewed literature demonstrating the efficacy of NPPV in certain settings, there are several unresolved issues … We will summarize issues of applicability qualitatively. V. References 1. … information to the EPC to identify literature search strategies and recommend approaches to specific issues
  6. effectivehealthcare.ahrq.gov/sites/default/files/pdf/hypothyroidism-hyperthyroidism-screening-treatment_research-protocol.pdf
    March 11, 2010 - Contextual Questions and Issues: 1. … (effect$ OR reaction$ OR event$ OR outcome$) [tiab] 10. 8 AND 9 11. 10 OR 7 OR 6 P Patient issues … identify literature search strategies, review the draft report and recommend approaches to specific issues … Contextual Questions and Issues:
  7. #14 SUBSTANCE ABUSE (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/substance-abuse-horizon-scan-high-impact-1412.pdf
    December 01, 2014 - Available: http://harmreduction.org/issues/overdose- prevention/overview/overdose-basics/responding … http://harmreduction.org/issues/overdose-prevention/overview/overdose-basics/responding-to-opioid-overdose … / http://harmreduction.org/issues/overdose-prevention/overview/overdose-basics/responding-to-opioid-overdose … / http://harmreduction.org/issues/overdose-prevention/overview/overdose-basics/responding-to-opioid-overdose
  8. #14 SUBSTANCE ABUSE (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/substance-abuse-horizon-scan-high-impact-1312.pdf
    December 01, 2013 - A long-acting formulation might address these issues. … The company was scheduled to meet with FDA on November 19, 2013, to discuss issues regarding the Probuphine … Project Lazarus aims to address these issues by offering a multifaceted, community-based approach to … this intervention agreed on the significant unmet need associated with the challenging public health issues
  9. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-bias_methods.pdf
    July 01, 2012 - Comparative Effectiveness Reviews (hereafter referred to as the General Methods Guide),1 and focuses on issues … Thus, this chapter highlights key issues when assessing risk of bias in studies evaluating medical tests—systematic … -3 diagnostic accuracy.3 As a guide to further work, the authors summarized the range of quality issues … a study otherwise makes a potentially important contribution to the review, reviewers may resolve issues
  10. effectivehealthcare.ahrq.gov/sites/default/files/pdf/women-hiv_research-protocol.pdf
    March 01, 2016 - Many older HIV-infected women face issues of stigma, poverty, sexual violence, and changes in relationships … Transgender men (people who were born female but identify as male) who live with HIV, likely face similar issues … All of these issues hinder the provision of individualized care. … not, engaged with the prison system vs not, experiencing violence vs not, experiencing mental health issues
  11. effectivehealthcare.ahrq.gov/sites/default/files/tech-brief-38-chronic-conditions-comments.pdf
    March 01, 2021 - We noted in the Discussion the issues about lack of access to the internet or smart phones as one … I am, however, surprised that two important issues are not addressed in the study. 1. … We suspect that any risk of bias issues arising from this would have already been captured by the … We have added specific content to the summary section noting these issues of generalizability given … There are likely many additional issues about PGHD technologies that our scope did not encompass.
  12. effectivehealthcare.ahrq.gov/sites/default/files/15_crosscutting_potential_high_impact_2012-12-11.pdf
    January 01, 2012 - This is especially a problem with nonemergency medical issues, home-health or social-service conditions … , and medical issues that could have been prevented if the patient had had regular access to primary … , and medical issues that could have been prevented if the patient had had regular access to primary … expert mentioned that about 50% of patients with chronic diseases experience prescription adherence issues … Including safety-net providers in integrated delivery systems: issues and options for policymakers
  13. Santa_ECCS2012 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/santa_eccs2012.pdf
    February 01, 2013 - Center for Farmworker Health participated in a focus  group and  identified  the  following  issues … Slide 29: Identified Issues From  Professional Societies • Harmonization • Safety • Use of brand
  14. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-updates_methods.pdf
    July 01, 2011 - This Guide presents issues key to the development of Comparative Effectiveness Reviews and describes … recommended approaches for addressing difficult, frequently encountered methodological issues. … individual study point estimates of relative risk (95percent confidence interval), respectively 10 Issues … In addition, knowledge of project history would be diminished or perhaps lost, and issues of replication … If an update involves new authors, it is important to discuss author issues as early in the updating
  15. effectivehealthcare.ahrq.gov/sites/default/files/pdf/dementia-agitation-aggression_research-protocol.pdf
    November 13, 2014 - Concern about these issues has led to clinical guidelines recommending non-pharmacologic interventions … Throughout the screening process, team members will meet regularly to discuss training material and issues … Source: www.effectivehealthcare.ahrq.gov Published online: November 13, 2014 12 measurement issues … than those described by population studies behavioral symptoms in dementia.42 These applicability issues … information to the EPC to identify literature search strategies and recommend approaches to specific issues
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/genetic-testing-developmental-disabilities_disposition-comments.pdf
    June 30, 2015 - to diagnose these disorders or determine a potential etiology, as well as some of the associated issues … We believe it is reasonable and important to discuss those issues related to interpreting the findings … We address the analytic validity issues in a later section in the report. Findings 3. … Relevant studies would need to be evaluated for study design/quality issues and strength of evidence … Peer Reviewer 1 Next Steps The issues for future research are well delineated.
  17. effectivehealthcare.ahrq.gov/sites/default/files/pdf/ankyloglossia_research-protocol.pdf
    June 30, 2014 - breastfeeding and address those related to tongue tie in later life (e.g., orthodontic and dental issues … Comments typically focused on treatment issues or limitations of the evidence base, including: • … function, failure to thrive, milk transfer, low milk supply, breastfeeding cessation • Other feeding issues … function, failure to thrive, milk transfer, low milk supply, breastfeeding cessation), other feeding issues … information to the EPC to identify literature search strategies and recommend approaches to specific issues
  18. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-2007_executive.pdf
    January 01, 2007 - Remaining Issues The review of existing evidence identified a number of issues requiring further research … These specific research issues are grouped by key question below. … Other general issues Future observational studies could improve understanding of the effects of oral … Conclusions Comparisons of effects of oral diabetes Differences in effectiveness between Remaining Issues … of life) For Key Questions 4 and 5 (adverse For Key Question 6 (differences across Other general issues
  19. effectivehealthcare.ahrq.gov/sites/default/files/pdf/incident-user-design_research.pdf
    May 01, 2012 - ................................................................................................1 Issues … Our paper considers the questions outlined above and related issues to start a dialogue on the value … Issues That Motivate the Incident User Design Investigators struggle to design non-randomized studies … Design issues for drug epidemiology. Br J Clin Pharmacol 2000;50:419-25. 12. … Current issues in non- inferiority trials. Statist Med 2008;27:317- 32. 29.
  20. effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/methods-guide-inclusion-nonrandomized-studies.pdf
    September 01, 2022 - for addressing difficult, frequently encountered methodological issues. … The workgroup received input from the full EPC Program regarding the process and specific issues through … Sections 8 and 9 expand on these issues. 1.2.5 Methods To Use When NRSIs Are Included Inclusion of … Section 10 expands on these issues. … Issues Related to Evolution of Evidence on a Topic The decision regarding inclusion of NRSIs in an

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