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Showing results for "issue".

441. DRN: Report 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/distributed-network-safety_research.pdf
     July 01, 2009 - DRN: Report 1 The DEcIDE (Developing Evidence to Inform Decisions about Effectiveness) network is part of AHRQ’s Effective Health Care program. It is a collaborative network of research centers that support the rapid development of new scientific information and analytic tools. The DEcIDE network assists heal…

442. The Evidence-Based Care Challenge: A Case Study (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/ebc-challenge-case-130621.pdf
     June 01, 2013 - The Evidence-Based Care Challenge: A Case Study The Evidence-Based Care Challenge: A Case Study Prepared for: Agency for Healthcare Research and Quality U.S. Department of Health and Human Services 540 Gaither Road Rockville, MD 20850 www.ahrq.gov Contract No. 290-2010-00005C Prepared …

443. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-children_executive.pdf
     February 01, 2012 - Layout 1 Introduction Antipsychotic medications are widely used to treat several psychiatric disorders and are commonly categorized into two classes. First-generation antipsychotics (FGAs), also known as typical antipsychotics, were developed in the 1950s. Although they are used to treat psychotic symptoms, they are…

444. Frameworks for Determining Research Gaps During Systematic Reviews (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-future-research-steps-framework_research.pdf
     June 01, 2011 - Uses the Implications for Research sections of all Cochrane reviews from one issue of the Cochrane … This was particularly an issue whenever no studies were identified for key questions with more than … For example, did studies that relied on banked samples from prior RCTs adequately address the issue … If no evidence is found to address a specific issue / PICO, and no studies are underway to address … the issue, then clearly a research gap exists.

445. PULMONARY with "Discussions" in Exec Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/13_pulmonary_potential_high_impact_june_2012.pdf
     January 01, 2012 - The $294,000 annual cost of ivacaftor therapy was identified as a potentially controversial issue. … The $294,000 annual cost of ivacaftor therapy was identified as a potentially controversial issue.

446. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/mental-illness-heart_research-protocol.pdf
     April 18, 2012 - The most important issue with respect to applicability is whether the outcomes are different across

447. Osteoporosis-Bone-Fracture Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoporosis-bone-fracture_executive.pdf
     March 01, 2012 - issues of particular interest were the continued use of placebo (as opposed to active) controls (an issue … Data are not consistent, nevertheless these data were sufficient for FDA to issue a Warning regarding

448. ASSESSING THE QUALITY OF INCLUDED STUDIES (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/assessing-the-risk-of-bias_draft-report.pdf
     June 02, 2011 - that EPCs set up clearly stated and consistent standards within their own reviews to deal with the issue … It then defers the issue of study design limitations to assessment of the strength of evidence. … that have minimal concordance what can be adopted in practice, the discrepancy may be considered an issue … guidelines on systematic reviews. 22 Risk of Bias and Conflict of Interest Many studies examining the issue … There is also the issue of establishing an association between the event and the intervention.

449. Disposition of Comments Report for Imaging Tests for the Diagnosis and Staging of Pancreatic Adenocarcinoma (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-pancreas_disposition-comments.pdf
     September 23, 2014 - Unfortunately, studies have not tackled this issue directly. … concern when using CT as part of a screening program (e.g. high risk kindreds), it is an irrelevant issue … multiple tests should be used together, we also looked for pertinent evidence, and unfortunately the issue … evidence on pages 34 and 46 of the main report), thus we could draw no relevant conclusions on this issue

450. Disposition of Comments Report for Evaluation and Treatment of Cryptorchidism (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/undescended-testicle_disposition-comments.pdf
     December 11, 2012 - Clearly the papers that are reviewed in this review, do not address this issue, as not enough time has … Peer Reviewer #1 General The second issue which needs to be more clearly articulated in the conclusions … We have added text related to this issue. … 2012 18 Commentator & Affiliation Section Comment Response Peer Reviewer #1 General Another issue

451. Dispostion of Comments Report for Screening for Hepatitis C Virus Infection in Adults (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c-screening_disposition-comments.pdf
     November 27, 2012 - Peer Reviewer # 4 Introduction Provides sufficient background on the HCV issue, the past recommendations … page 2, paragraph 2, line 3: the references provided in the second and third comments speak to this issue … We added a sentence to clarify the issue regarding interpretation of liver biopsies for guiding treatment … We respect your position is to look at this as a healthcare quality issue but hepatitis C is an infectious … The Federal government has provided too little resources to effectively study this issue which results

452. Effective Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0122_06-29-2009.pdf
     January 01, 2009 - Effective Health Care Topic Number: 0163 Document Completion Date: 6-7-10 1 Results of Topic Selection Process & Next Steps  Nitrous oxide for the management of labor pain will go forward for refinement as a systematic review. The scope of this topic, including populations, interventions, co…

453. Chicago-Area DEcIDE Center (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/off-label-use-research-priorities_research.pdf
     May 01, 2009 - Quality of the Data T o E xamine Off-label P res c ribing A fundamental issue in the future assessment … with inadequate or uncertain scientific evidence warrants substantial future efforts to address this issue … used for selection: 1) Based on their experience, potential panel members were familiar with the issue

454. Continuous-Outcomes-Quantitative-Synthesis Methods (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/continuous-outcomes-quantitative-synthesis_methods.pdf
     March 01, 2011 - We also briefly discuss the issue of incorporating correlation into calculation of SD for crossover … Dealing With Missing Data Missing data is a common issue in meta-analysis and often leads to biased … This section focuses on the issue of missing summary data, which is most relevant to continuous data … Study-Level Characteristics Individuals missing from a study due to withdrawal and other reasons create an issue … In addition, investigators should note that the multiplicity of data is a potential issue for

455. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-ovarian-contraceptives_research-protocol.pdf
     March 13, 2012 - Evidence-based Practice Center Systematic Review Protocol Source: www.effectivehealthcare.ahrq.gov Published Online: March 13, 2012 1 Evidence-based Practice Center Systematic Review Protocol Project Title: Oral Contraceptive Use for the Primary Prevention of Ovarian Cancer Amendment Date(s) if applicabl…

456. SRDR-Charter-140305 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/data-repository-reviews-charter-140305.pdf
     June 01, 2012 - SRDR-Charter-140305 Charter  of SRDR V.10 Article I – Purpose/Goals of SRDR Article II – Governance Board   Article III – Operational Team of SRDR SRDR is being developed  and  maintained by the Brown EPC under contract with the Agency for Healthcare Research and Quality (AHRQ), Rockville, MD   (Contract…

457. Trauma-Interventions-Maltreatment-Child Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/trauma-interventions-maltreatment-child_executive.pdf
     April 01, 2013 - A major gap in the literature with implications for widespread implementation is the issue of “dose” … None of the included studies addressed this issue. … Power analyses were seldom presented; this finding speaks to a serious issue in the field that contributes … Retention: We were able to find only one comparative study for inclusion in this review relevant to the issue

458. Untitled (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/infertility_research-protocol.pdf
     October 12, 2015 - The most important issue with respect to applicability is whether the outcomes are different across

459. Slide 1
     effectivehealthcare.ahrq.gov/sites/default/files/exposure-definition-and-measurement_chapter-4.pptx
     January 01, 2013 - Slide 1 Exposure Definition and Measurement in Observational Comparative Effectiveness Research Prepared for: Agency for Healthcare Research and Quality (AHRQ) www.ahrq.gov Exposure Definition and Measurement in Observational Comparative Effectiveness Research This slide set is based on a user guide titled Develop…

460. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/disabilities-quality-improvement-outcomes_research-protocol.pdf
     August 03, 2011 - Evidence-based Practice Center Systematic Review Protocol 1 Source: www.effectivehealthcare.ahrq.gov Published Online: August 3, 2011 Evidence-based Practice Center Systematic Review Protocol Project Title: Closing the Quality Gap Series: Measuring Outcomes of Care for Persons With Disabilities I…