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  1. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-264-maternal-morbidity-mortality-disposition-comments.pdf
    December 21, 2023 - with the lengthy paragraph required to explain the figure, which introduces another accessibility issue … at a different hospital reduce morbidity (e.g., is something inherent in the hospital causing the issue … Mixed methods studies won’t eliminate that issue, but inclusion of mixed-methods studies in the future
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/labor-nitrous-oxide_research-protocol.pdf
    August 24, 2011 - Labor pain management in the United States: understanding patterns and the issue of choice.
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-cholestorol-medicines-update_disposition-comments.pdf
    September 01, 2014 - As pointed out in an editorial published in the same issue of NEJM as the ARBITER 6 study, use of this … Problems with adherence must be considered both a safety and efficacy issue in my view. … differed between lower- potency combination therapy and higher-dose statin monotherapy, however, this issue … at the genotype of the Added to “Implications for Clinical and Policy-Decision Making” Another issue … We also address this issue in the Important Unanswered Questions section: “We found very limited evidence
  4. effectivehealthcare.ahrq.gov/sites/default/files/related_files/hro-protocol.pdf
    January 01, 2023 - Making Healthcare Safer IV: High Reliability Organization (HRO) as a Patient Safety Practice Evidence-based Practice Center Rapid Review Protocol Project Title: Making Healthcare Safer IV: High Reliability Organization (HRO) as a Patient Safety Practice Review Questions Review Question Based on t…
  5. effectivehealthcare.ahrq.gov/sites/default/files/tech-brief-32-pharm-non-pharm-ptsd.pdf
    May 14, 2019 - of the project does not include assessing or reporting the risk of bias of the studies, but this issue … TEP Reviewer #7 Clarity and Usability With the exception of the PC practice issue mentioned above, … 3 month data starts on different lines in each column) We do recognize that this as a potential issue … I do have one issue in mind about ensuring the database will represent PC practice that includes subsyndromal
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/abnormal-uterine-bleeding_disposition-comments.pdf
    March 21, 2013 - This problem is present throughout the writing, but is particularly an issue with the Applicability … between heavy bleeding and thrombosis, this should be presented in a straightforward manner, and this issue … This is an issue that should be engaged, and is particularly concerning in the “Future Research Needs … ” section (Page 117, Line 26) Related to this is an overall inadequate attention to the issue of AUB-C
  7. effectivehealthcare.ahrq.gov/sites/default/files/interventions-horizon-scan-high-impact-1306.pdf
    June 01, 2013 - Most experts raised the issue of funding and noted that this program will require either government
  8. effectivehealthcare.ahrq.gov/sites/default/files/cer-232-breathlessness-cancer-comments.pdf
    November 19, 2020 - Introduction Overall, the introduction is clear and concise, and lays out the significance of the issue … in other recent systematic reviews, but we definitely agree that comorbid COPD is a very important issue … This is mainly an issue for the buccal tablet as IN and SC doses are given quickly. … There is an issue of balance in the report’s conclusion regarding opioids that needs to refined with
  9. effectivehealthcare.ahrq.gov/sites/default/files/introduction-to-user-guide-overview.pptx
    January 01, 2013 - Yet, it is rare that any one study addresses all dimensions of a health care issue; there are often knowledge
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/weight-loss-surgery_disposition-comments.pdf
    June 05, 2013 - None needed Peer Reviewer 7 Methods Appropriate None needed TEP 1 Methods Please note the ethnicity issue … poorer results when compared with BMI> 35 in italians We have added more discussion of the ethnicity issue … However, as your report suggests, these trials are difficult and the issue of randomization to surgical … This issue is discussed in the applicability section. … Clearly, this is a major national health issue that deserves the attention of multiple medical and
  11. effectivehealthcare.ahrq.gov/sites/default/files/related_files/coronary-artery-stenting_disposition-comments.pdf
    February 26, 2013 - 2013 8 Commentator & Affiliation Section Comment Response Peer Reviewer 4 Results An important issue
  12. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-220-disposition-comments-analgesics-prehospital-setting.pdf
    September 03, 2019 - TEP reviewer #6 Results Only issue would be preference for ketamine for patients who would not otherwise … pain medication ‐specifically the multi‐traumatized patient or patient in shock, Addressing this issue … Peer reviewer #4 Discussion Page 71 Line 34-36: Same issue as above under Page 26. … Comment Response TEP reviewer #5 General Use of these medications in older individuals ‐ this issue … The AHRQ is to be commended for their work on this timely and important issue.
  13. effectivehealthcare.ahrq.gov/sites/default/files/pdf/restless-legs-future_research.pdf
    February 01, 2013 - Treatment for Restless Legs Syndrome: Future Research Needs Future Research Needs Paper Number 38 Treatment for Restless Legs Syndrome: Future Research Needs Future Research Needs Paper Number 38 Treatment for Restless Legs Syndrome: Future Research Needs Identification of Future Research Needs From Co…
  14. effectivehealthcare.ahrq.gov/sites/default/files/related_files/lysosomal-storage-diseases-therapies_disposition-comments.pdf
    January 01, 2014 - that these are unique diseases with unique treatments, a title change may be helpful to clarify the issue … The issue of stopping ERT when therapy becomes futile did arise in our discussions and is alluded to … Although reaching maximum lifetime insurance limits may have been an issue for some LSD patients in … An issue to consider is immune modulation in such patients; there are a few publications on this. … Thus, whether to initiate ERT in patients with a genetic mutation specific for a LSD is an issue for
  15. effectivehealthcare.ahrq.gov/sites/default/files/antipsychotics-children-update-disposition-170621.pdf
    March 16, 2017 - This is a huge issue because drawing blood in some children/adults with disabilities may require sedation … It is critical that this issue be addressed. … the only comment about difficulty following/understanding the text we don’t think there’s a large issue … consider also uncontrolled prospective studies as "clinical trials" Thanks for pointing out this issue … Another issue is the statement that none of the evidence was rated “high strength of evidence”.
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-children-update-disposition-170621.pdf
    March 16, 2017 - This is a huge issue because drawing blood in some children/adults with disabilities may require sedation … It is critical that this issue be addressed. … the only comment about difficulty following/understanding the text we don’t think there’s a large issue … consider also uncontrolled prospective studies as "clinical trials" Thanks for pointing out this issue … Another issue is the statement that none of the evidence was rated “high strength of evidence”.
  17. effectivehealthcare.ahrq.gov/sites/default/files/study-eligibility-criteria.ppt
    January 01, 2000 - Study Eligibility Criteria Study Eligibility Criteria Agency for Healthcare Research and Quality (AHRQ) Training Modules for Methods Guide for Effectiveness and Comparative Effectiveness Reviews Study Eligibility Criteria Systematic Review Process Overview * Systematic Review Process Overview This slide illu…
  18. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-report-anxiety-children_0.pdf
    October 01, 2018 - In brief, clinicians were instructed to ask patients for the issue most important to them when making … Then, patients were asked about the second most important issue, and so forth. 4 Data used to
  19. effectivehealthcare.ahrq.gov/sites/default/files/15_crosscutting_potential_high_impact_2012-12-11.pdf
    January 01, 2012 - Most experts raised the issue of funding and noted that this program will require either government … (Issue Brief; no. 1617).
  20. effectivehealthcare.ahrq.gov/sites/default/files/pdf/mrsa-screening_research.pdf
    June 01, 2013 - One key issue is to identify the appropriate populations for screening as this has implications for … The challenge in studying this issue in terms of health outcomes such as newly documented MRSA infections … Enrollment and consent of critically ill or urgent care patients could be an issue.

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