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  1. effectivehealthcare.ahrq.gov/sites/default/files/pdf/labor-nitrous-oxide_research-protocol.pdf
    August 24, 2011 - Labor pain management in the United States: understanding patterns and the issue of choice.
  2. effectivehealthcare.ahrq.gov/sites/default/files/cer-232-breathlessness-cancer-comments.pdf
    November 19, 2020 - Introduction Overall, the introduction is clear and concise, and lays out the significance of the issue … in other recent systematic reviews, but we definitely agree that comorbid COPD is a very important issue … This is mainly an issue for the buccal tablet as IN and SC doses are given quickly. … There is an issue of balance in the report’s conclusion regarding opioids that needs to refined with
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-cholestorol-medicines-update_disposition-comments.pdf
    September 01, 2014 - As pointed out in an editorial published in the same issue of NEJM as the ARBITER 6 study, use of this … Problems with adherence must be considered both a safety and efficacy issue in my view. … differed between lower- potency combination therapy and higher-dose statin monotherapy, however, this issue … at the genotype of the Added to “Implications for Clinical and Policy-Decision Making” Another issue … We also address this issue in the Important Unanswered Questions section: “We found very limited evidence
  4. effectivehealthcare.ahrq.gov/sites/default/files/related_files/abnormal-uterine-bleeding_disposition-comments.pdf
    March 21, 2013 - This problem is present throughout the writing, but is particularly an issue with the Applicability … between heavy bleeding and thrombosis, this should be presented in a straightforward manner, and this issue … This is an issue that should be engaged, and is particularly concerning in the “Future Research Needs … ” section (Page 117, Line 26) Related to this is an overall inadequate attention to the issue of AUB-C
  5. effectivehealthcare.ahrq.gov/sites/default/files/interventions-horizon-scan-high-impact-1306.pdf
    June 01, 2013 - Most experts raised the issue of funding and noted that this program will require either government
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/coronary-artery-stenting_disposition-comments.pdf
    February 26, 2013 - 2013 8 Commentator & Affiliation Section Comment Response Peer Reviewer 4 Results An important issue
  7. effectivehealthcare.ahrq.gov/sites/default/files/introduction-to-user-guide-overview.pptx
    January 01, 2013 - Yet, it is rare that any one study addresses all dimensions of a health care issue; there are often knowledge
  8. effectivehealthcare.ahrq.gov/sites/default/files/pdf/restless-legs-future_research.pdf
    February 01, 2013 - Treatment for Restless Legs Syndrome: Future Research Needs Future Research Needs Paper Number 38 Treatment for Restless Legs Syndrome: Future Research Needs Future Research Needs Paper Number 38 Treatment for Restless Legs Syndrome: Future Research Needs Identification of Future Research Needs From Co…
  9. effectivehealthcare.ahrq.gov/system/files/docs/topic-brief-hospital-length-of-stay.pdf
    November 01, 2019 - Issue: Unnecessary days in the hospital can lead to patient complications and increases costs. … Why are you struggling with this issue? … How will you know that your issue is improving or has been addressed? … Why are you struggling with this issue? 3. What do you want to see changed? … How will you know that your issue is improving or has been addressed? 4.
  10. effectivehealthcare.ahrq.gov/sites/default/files/mccormack-presentation.pdf
    May 29, 2025 - recognizing the need for broader healthcare reformsand  system wide thinking in  terms of rectifying the issue
  11. effectivehealthcare.ahrq.gov/sites/default/files/study-eligibility-criteria.ppt
    January 01, 2000 - Study Eligibility Criteria Study Eligibility Criteria Agency for Healthcare Research and Quality (AHRQ) Training Modules for Methods Guide for Effectiveness and Comparative Effectiveness Reviews Study Eligibility Criteria Systematic Review Process Overview * Systematic Review Process Overview This slide illu…
  12. effectivehealthcare.ahrq.gov/sites/default/files/related_files/lysosomal-storage-diseases-therapies_disposition-comments.pdf
    January 01, 2014 - that these are unique diseases with unique treatments, a title change may be helpful to clarify the issue … The issue of stopping ERT when therapy becomes futile did arise in our discussions and is alluded to … Although reaching maximum lifetime insurance limits may have been an issue for some LSD patients in … An issue to consider is immune modulation in such patients; there are a few publications on this. … Thus, whether to initiate ERT in patients with a genetic mutation specific for a LSD is an issue for
  13. effectivehealthcare.ahrq.gov/sites/default/files/15_crosscutting_potential_high_impact_2012-12-11.pdf
    January 01, 2012 - Most experts raised the issue of funding and noted that this program will require either government … (Issue Brief; no. 1617).
  14. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-report-anxiety-children_0.pdf
    October 01, 2018 - In brief, clinicians were instructed to ask patients for the issue most important to them when making … Then, patients were asked about the second most important issue, and so forth. 4 Data used to
  15. effectivehealthcare.ahrq.gov/sites/default/files/pdf/mrsa-screening_research.pdf
    June 01, 2013 - One key issue is to identify the appropriate populations for screening as this has implications for … The challenge in studying this issue in terms of health outcomes such as newly documented MRSA infections … Enrollment and consent of critically ill or urgent care patients could be an issue.
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/wireless-motility-capsule_disposition-comments.pdf
    May 20, 2013 - Three studies evaluated that issue and reported a change in management in 50-69% of patients. … Likewise there were two studies that addressed this issue for KQ3 and did suggest that WMC changed … The Kuo study is included and is in our opinion the main paper that evaluates this issue. … We believe the issue of x-ray is somewhat based on the population. … Thus, bias was a major issue impacting the SOE.
  17. effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-cancer-medications_disposition-comments.pdf
    March 10, 2010 - And, in "prevention" trials, isn't the most important issue whether you reduce the risk of death from
  18. effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoporosis-vibration-therapy_technical-brief.pdf
    January 01, 2020 - Whole-Body Vibration Therapy for Osteoporosis Whole-Body Vibration Therapy for Osteoporosis Technical Brief Number 10 Technical Brief Number 10 Whole-Body Vibration Therapy for Osteoporosis Prepared for: Agency for Healthcare Research and Quality U.S. Department of Health and Human Services 540 G…
  19. effectivehealthcare.ahrq.gov/sites/default/files/related_files/alcohol-misuse-drug-therapy_disposition-comments.pdf
    May 13, 2014 - We also added more explicit statements about this issue in the Results of the Executive Summary and … We also added a footnote to explain the issue raised here for accidents and injuries. … a) We have included text on this issue in the Applicability section. … This important issue needs more discussion and data. … We have not had anyone else raise this issue as one of importance.
  20. #14 SUBSTANCE ABUSE (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/substance-abuse-horizon-scan-high-impact-1312.pdf
    December 01, 2013 - #14 SUBSTANCE ABUSE AHRQ Healthcare Horizon Scanning System – Potential High-Impact Interventions Report Priority Area 14: Substance Abuse Prepared for: Agency for Healthcare Research and Quality U.S. Department of Health and Human Services 540 Gaither Road Rockville, MD 20850 www.ahrq.…

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