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  1. effectivehealthcare.ahrq.gov/sites/default/files/methods_guide_atkins.pdf
    January 01, 2011 - Cochrane Database of Systematic Reviews 2007, Issue 2. Art. No.: CD002755. … Cochrane Database of Systematic Reviews 2005, Issue 4. Art. No.: CD001923.
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-children_research-protocol.pdf
    June 04, 2010 - Source: www.effectivehealthcare.ahrq.gov Published Online: June 04, 2010 Evidence-based Practice Center Systematic Review Protocol Project Title: Comparative Effectiveness of First and Second Generation Antipsychotics in the Pediatric and Young Adult Populations I. Background and Objectives for th…
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/recombinant-factor-viia_disposition-comments.pdf
    June 01, 2010 - Methods Systematic Review The report acknowledges in multiple places that the issue of clinical … The report notes that the issue of clinical homogeneity of pooled studies requires care (page 26). … An obvious issue is the need to continually refer back to Fig 5 & 6 p 90 when considering the results … We have addressed this issue in the “Other considerations” section with the following sentence (page … examined across indication,” the report takes a cautious and clinically-oriented approach to this issue
  4. effectivehealthcare.ahrq.gov/sites/default/files/pdf/rapid-reviews-end-user_white-paper.pdf
    April 01, 2016 - end-users of AHRQ EPC systematic reviews identified the following themes:  Trust was the primary issue … moment sort of decisions”; to act as an update for a previous comprehensive guideline or address an issue … secondary or subsequent to a guideline; or, to get a general sense of the literature or scale of the issue …  Related to the above issue, KIs commented on the risk that a rapid product might give the wrong … Cochrane Database of Systematic Reviews 2011, Issue 8. Art. No.: MR000026.
  5. effectivehealthcare.ahrq.gov/sites/default/files/pdf/cesarean-birth_research.pdf
    January 01, 2020 - Methodologic issues identified in the Comparative Effectiveness Review Methodologic Issue Relevant PICOTS … Stakeholders would be able to address this issue in the next two prioritization steps.
  6. #14 SUBSTANCE ABUSE (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/substance-abuse-horizon-scan-high-impact-1506.pdf
    June 01, 2015 - need and health outcomes: Most experts stated that opioid overdose is a significant public health issue … rates of alcohol dependence, morbidity, and mortality.28-31 Hazardous alcohol use is a public health issue … health outcomes: Experts universally agreed that hazardous alcohol use is a significant public health issue
  7. effectivehealthcare.ahrq.gov/sites/default/files/ch_5-user-guide-to-ocer_130129.pdf
    January 01, 2012 - socioeconomic status. 64 Developing an Observational CER Protocol: A User’s Guide A separate issue
  8. effectivehealthcare.ahrq.gov/sites/default/files/pdf/health-systems-research.pdf
    October 01, 2017 - Using inter-professional committees within a medical subspecialty to understand the issue, the current … systematic review summary that allows the reader to decide if the report was “fit to the purpose” for an issue … Health-systems go from issue identification or metric discrepancy to fashioning process changes in a
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-abnormalities-tests-update_disposition-comments.pdf
    February 13, 2012 - Yes, this is a complex issue to address. … We have added text to clarify the issue. … The issue of prior ultrasounds has been addressed in the points above. … The issue of applicability was addressed separately and was not incorporated into the generally low
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-264-maternal-morbidity-mortality-disposition-comments.pdf
    December 21, 2023 - with the lengthy paragraph required to explain the figure, which introduces another accessibility issue … at a different hospital reduce morbidity (e.g., is something inherent in the hospital causing the issue … Mixed methods studies won’t eliminate that issue, but inclusion of mixed-methods studies in the future
  11. effectivehealthcare.ahrq.gov/sites/default/files/comparator-selection-in-observational-chapter-5.pptx
    January 01, 2013 - One issue with no-treatment comparison groups is how to identify time 0. … Another way to handle this issue is to allow a different time 0 for the treatment and no-treatment groups … A separate issue of generalizability, which could arise as an estimation of a causal effect in observational
  12. effectivehealthcare.ahrq.gov/sites/default/files/pdf/mental-illness-disparities_research-protocol.pdf
    July 01, 2015 - Research Protocol: Disparities Within Serious Mental Illness Evidence-based Practice Center Project Title: Disparities within Serious Mental …
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/hro-protocol.pdf
    January 01, 2023 - Making Healthcare Safer IV: High Reliability Organization (HRO) as a Patient Safety Practice Evidence-based Practice Center Rapid Review Protocol Project Title: Making Healthcare Safer IV: High Reliability Organization (HRO) as a Patient Safety Practice Review Questions Review Question Based on t…
  14. effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-cough_disposition-comments.pdf
    January 07, 2013 - Peer Reviewer #2 General KQ1: A key issue: Cough counting although a potential measure of cough severity … Had they done this, they then could have commented upon how well the literature addressed the issue
  15. effectivehealthcare.ahrq.gov/products/eccs-2009/white-paper-2009-3
  16. effectivehealthcare.ahrq.gov/sites/default/files/tech-brief-32-pharm-non-pharm-ptsd.pdf
    May 14, 2019 - of the project does not include assessing or reporting the risk of bias of the studies, but this issue … TEP Reviewer #7 Clarity and Usability With the exception of the PC practice issue mentioned above, … 3 month data starts on different lines in each column) We do recognize that this as a potential issue … I do have one issue in mind about ensuring the database will represent PC practice that includes subsyndromal
  17. effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetes-behavior-programs_clinician-2016.pdf
    January 01, 2016 - Behavioral Programs for Type 1 Diabetes Mellitus: Current State of the Evidence Behavioral Programs for Type 1 Diabetes Mellitus: Current State of the Evidence Focus of This Summary This is a summary of a systematic review evaluating the evidence about the effectiveness of behavioral programs for type 1 diabete…
  18. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-201-indoor-allergen-asthma-disposition-comments.pdf
    February 15, 2018 - CRI will restrict these comments to the issue of the effectiveness of indoor allergen reductions addressed … are certainly issues with adherence to the drug in drug trials, this by and large is a very small issue … are certainly issues with adherence to the drug in drug trials, this by and large is a very small issue … Public Reviewer 12 Melanie Carver on behalf of AAFA Results Another issue is that many of the studies … We have expanded the Discussion section to address this important issue.
  19. effectivehealthcare.ahrq.gov/sites/default/files/related_files/rheumatoid-arthritis-medicine_surveillance.pdf
    March 01, 2013 - Is the portion of the CER that is probably or certainly out of date an issue of safety (a drug withdrawn
  20. effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine_surveillance.pdf
    March 01, 2013 - Is the portion of the CER that is probably or certainly out of date an issue of safety (a drug withdrawn

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