August 24, 2012 - This was a formatting issue, bullets were added
to the figure as suggested by the reviewer. … In order to emphasize this limitation, we have
referenced this issue in the abstract (under
limitations … We added a brief discussion of this
issue to the summary and discussion chapter. … We added a brief discussion of this issue to the
summary and discussion chapter. … We added a brief discussion of this issue to the
summary and discussion chapter.
December 01, 2011 - At some point should address the issue
of nomenclature: whether some minimal‐risk
prostate cancers … There is a very brief reference to this issue in
the research section, but it may be
worthwhile to … Will Rogers is more an issue
when it comes to questions like extent of
lymphadenectomy and quality … The goal going forward is to
move toward consensus across prospective
cohorts, and this issue is not … We agree this is a key issue for the conference
attendees to discuss.
October 01, 2013 - children-special-needs-transition-protocol-131003
Evidence-based Practice Center Te c h n i c a l B rie f P r o t o co l
Project Title: Transitions Care for Children With Sp…
July 01, 2011 - Preventive Services Task Force (USPSTF) has addressed the issue of updating its
clinical guideline … and followed up 362 SRs in the Cochrane Database of SRs
from their original publication in 1998 (Issue … 2) to 2002 (Issue 2).
February 01, 2021 - Evidence Summary: CER 237_Integrating Palliative Care in Ambulatory Care of Noncancer Serious Chronic Illness
Comparative Effectiveness Review
Number 237
Integrating Palliative Care in Ambulatory
Care of Noncancer Serious Illness
Evidence Summary
Main Points
Background and Purpose
In the Unit…
May 01, 2014 - • The domain is a topic, issue, or concern of interest shared by the individuals who
participate … implementation of a Web-based CoP, and advised that the sponsor proactively consider how to
address this issue … or altruism.42 The sponsor should encourage this viewpoint while marketing the CoP
and address the issue … Existing Web-based CoPs have approached this issue in different ways, depending upon their
individual
February 01, 2013 - Availability of data/ability to
recruit
Not likely to be an issue given the prevalence of knee OA. … Availability of
data/ability to recruit
Not likely to be an issue given the prevalence
of Knee OA … Not likely to be an issue given the prevalence of
Knee OA. … Availability of data/ability to
recruit
Not likely to be an issue given the prevalence of knee OA. … Availability of
data/ability to recruit
Not likely to be an issue given the prevalence of knee OA
May 27, 2010 - This issue requires more study.
No action necessary.
General
Comment
4. … If the issue of equipoise is at play in the
eyes of first degree stakeholders, would such a trial be … Further, .
. . continues to independently and aggressively engage the issue of IMRT terminology
and … This issue requires more study.
No action necessary.
General
Comment
4.
September 29, 2014 - The authors also should explicitly recognize the degree to which
the issue of pharmacogenomics can challenge … For another issue, even with the information provided
in Appendix E it remains difficult to appreciate … In light of the foundational nature of this issue, it
seems incumbent on the authors to indicate the … I think that the issue of abuse/addiction
was handled particularly well in that the lack of uniformity … Peer Reviewer 7 General
Comments
The issue of the relationship between chronic opioid use and both
May 29, 2013 - For KQ6, the 1st 4 key points deal with the rather unimportant issue of IVCF use
rather than the much … that the patients in
the studies reflect the typical population
We agree and have discussed this issue … To address the
selection bias issue, the authors recently conducted a propensity matched analysis
which … As always the key issue will be funding
research in special populations. … is usually
considered a complication of DVT
We appreciate the comments and have
clarified this issue
June 01, 2013 - #14 SUBSTANCE ABUSE
AHRQ Healthcare Horizon Scanning System – Potential
High-Impact Interventions Report
Priority Area 14: Substance Abuse
Prepared for:
Agency for Healthcare Research and Quality
U.S. Department of Health and Human Services
540 Gaither Road
Rockville, MD 20850
www.ahrq.…
July 10, 2012 - This is primarily a population level issue. … There
are many studies identified which address this issue. … See response to comment #1 (as this
comment is directly related to that issue). … We have included a paragraph about the
assessment issue in the ES as well as in the
Discussion. … This is
not a small semantic or grammatical issue.
July 01, 2012 - To better
address this issue of potential variability by
diagnostic groups, we have modified our
presentation … Again, my
main issue about the analysis is stated in the General Comments above,
regarding the decision … As described above, we considered this issue
carefully and give summary estimates by
subgroups when … We considered this issue but do not
think it is an important source of bias for this
outcome. … To better
address this issue of potential variability by
diagnostic groups, we have modified our
presentation
May 14, 2025 - We have searched and corrected the two
instances of this issue. … Further, on
the issue of industry sponsorship and risk of
bias, we note the following language from … Finally, although the report raises the issue
of alternative endpoints, it does little to
recognize … Not cited was
a paper that directly assessed this issue
and concluded that “MCED-detected
cancers … We have updated and
revised the references with respect to this
issue.
November 04, 2020 - There is the issue of how to get an
overall ROB rating. … And separately there is the
issue of how 2 items might interact (eg maybe
dont ding for unblinding … We agree that this is a complicated issue. … General
Comments
Whichever approach you decide is best going
forward, I think that an important issue … November 4, 2020
29
Commenter and
Affiliation Section Comment Response
Peer Reviewer 3 Results The issue