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  1. effectivehealthcare.ahrq.gov/sites/default/files/related_files/antiplatelet-treatment_disposition-comments.pdf
    September 25, 2013 - We believe that the changes address this issue. … An important study, the RAPIDGENE study (PMID:22464343) addressed the issue of tailoring antiplatelet … The review does not address the issue of poor metabolism, that is, carriage of two loss-of-function … If this is indeed the issue, this should be made clearer and there should be a brief discussion about … Peer Reviewer #12 Methods In addition, while the issue of study heterogeneity and how to consider it
  2. effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoporosis-bone-fracture_disposition-comments.pdf
    March 01, 2012 - Data are not consistent, nevertheless these data were sufficient for FDA to issue a Warning regarding … While we agree that the evidence is scant regarding this issue, we feel that is all the more reason … We have added a discussion of this issue to the Methods section. … For the individual studies, it could be a power issue, instead of lack of association. … There is EPC guidance on this issue: see Whitlock EP, Lin JS, Chou R, Shekelle P, Robinson KA.
  3. effectivehealthcare.ahrq.gov/sites/default/files/pdf/improving-utility-evidence-synthesis-white-paper.pdf
    April 01, 2021 - Methods White Paper: Improving the Utility of Evidence Synthesis for Decision Makers in the Face of Insufficient Evidence Methods White Paper Improving the Utility of Evidence Synthesis for Decision Makers in the Face of Insufficient Evidence Methods White Paper Improving the Utility of Evidence Synthesis …
  4. effectivehealthcare.ahrq.gov/sites/default/files/related_files/trauma-informed-care-disposition-comments.pdf
    January 14, 2025 - University National Center for Child Traumatic Stress Network General comments Another important issue
  5. effectivehealthcare.ahrq.gov/sites/default/files/pdf/registry-of-patient-registries_research-2012-2_1.pdf
    January 01, 2012 - Second, the issue was considered from a health care journal perspective since the decision by the International
  6. effectivehealthcare.ahrq.gov/sites/default/files/ch_4-user-guide-to-ocer_130129.pdf
    January 01, 2010 - 45 Abstract Characterization of exposure is a central issue in the analysis of observational data; … To expand upon the latter issue, data from health systems like insurance companies often lack the ability
  7. effectivehealthcare.ahrq.gov/sites/default/files/related_files/autism-adolescents_disposition-comments.pdf
    August 27, 2012 - these clinical decisions will have to depend on discussion between client and practitioner. the key issue … This is largely a reporting issue. … Again, this is largely a reporting issue, as several articles refer to procedures for monitoring fidelity … Thus, another critical issue is to design interventions for implementation in such settings. … The only issue I was left wondering about was how "20" was determined.
  8. #14 SUBSTANCE ABUSE (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/substance-abuse-horizon-scan-high-impact-1406.pdf
    January 01, 2020 - positive assessment of this intervention and its high potential to address a critical public health issue … opioid-associated overdoses and deaths.1,2 Opioid overdose represents a significant national public health issue … per- capita overdose rate was third highest in the nation.3,4 Project Lazarus aims to address this issue
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/measuring-blood-pressure_disposition-comments.pdf
    January 01, 2012 - & Affiliation Section Comment Response Peer Reviewer 2 Introduction Appropriate framing of the issue … The journal Blood Pressure Monitoring also publishes new validation studies nearly every issue. … Another semantic issue arises on page 94. … Peer Reviewer 2 General An exhaustive, well written analysis of a clinically important issue.
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/suicide-prevention_disposition-comments.pdf
    October 04, 2016 - The authors should be commended for conducting such a thorough systematic review of an issue that has … Minor technical issue: I would suggest increasing the font size in the text boxes to improve readability … explained thoroughly and were an excellent approach to hashing out the facets of this challenging issue … We agree that this is an important issue and this is now included in the Discussion: “Data linkage
  11. effectivehealthcare.ahrq.gov/sites/default/files/related_files/postpartum-care-one-year-disposition-comments.pdf
    June 02, 2023 - We have added text describing this issue in the Abstract. … My broader view of this issue of continuity, is that wealthier and more highly resourced individuals
  12. effectivehealthcare.ahrq.gov/sites/default/files/cer-238-cervical-ripening-outpatient-setting-comments.pdf
    March 22, 2021 - This is an important issue, and we have reviewed the evidence on patient preferences and satisfaction
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/hospital-length-of-stay-disposition-comments_0.pdf
    September 20, 2021 - The dearth of data regarding patients with social and economic barriers is a large issue. … This is a large issue.
  14. effectivehealthcare.ahrq.gov/sites/default/files/module-ii-stakeholders-and-stakeholder-engagement.pdf
    June 01, 2011 - Module II: Stakeholders and Stakeholder Engagement …
  15. effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-children-future_research.pdf
    February 01, 2012 - Future Research Needs for First- and Second-Generation Antipsychotics for Children and Young Adults Future Research Needs Paper Number 13 Future Research Needs for First- and Second- Generation Antipsychotics for Children and Young Adults Future Research Needs Paper Number 13 Future Research Needs for F…
  16. effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/registry-of-patient-registries_research-2014.pdf
    January 01, 2014 - This issue is discussed further in the Maintenance section below. … In particular, the stakeholder discussions identified an issue with collecting and presenting all relevant … The issue of including the individual data elements may need to be reassessed after a pilot period of
  17. effectivehealthcare.ahrq.gov/sites/default/files/cer-237-evidence-summary-palliative-care-ambulatory.pdf
    February 01, 2021 - Evidence Summary: CER 237_Integrating Palliative Care in Ambulatory Care of Noncancer Serious Chronic Illness Comparative Effectiveness Review Number 237 Integrating Palliative Care in Ambulatory Care of Noncancer Serious Illness Evidence Summary Main Points Background and Purpose In the Unit…
  18. effectivehealthcare.ahrq.gov/sites/default/files/pdf/autism-update_clinician.pdf
    September 01, 2014 - Summary Comparative Effectiveness of Therapies for Children With Autism Spectrum Disorder Key Clinical Issue
  19. effectivehealthcare.ahrq.gov/sites/default/files/pdf/children-special-needs-transition_research-protocol.pdf
    October 01, 2013 - children-special-needs-transition-protocol-131003 Evidence-based Practice Center Te c h n i c a l B rie f P r o t o co l Project Title: Transitions Care for Children With Sp…
  20. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-updates_methods.pdf
    July 01, 2011 - Preventive Services Task Force (USPSTF) has addressed the issue of updating its clinical guideline … and followed up 362 SRs in the Cochrane Database of SRs from their original publication in 1998 (Issue … 2) to 2002 (Issue 2).

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