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  1. 8 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/methodsguide_chou_assessing_harms_when_comparing.pdf
    November 01, 2008 - For unexpected adverse events, for example, confounding by indication may not be as important an issue
  2. effectivehealthcare.ahrq.gov/sites/default/files/related_files/labor-nitrous-oxide_disposition-comments.pdf
    August 23, 2012 - Key Question 2 addresses the issue of nitrous oxide's impact on women's satisfaction. … Cochrane Database of Systematic Reviews 2011, Issue 12. Art. No.: CD000331. … , methoxyflurane has been ruled out as an analgesic for labor, so it is not really relevant to the issue … We did not find any studies that address the issue of abuse. … Reviewer #10 Results page 18 -- lines 18-20 -- Key Question 5 -- The issue of abuse potential among
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-women-diagnosis_disposition-comments.pdf
    June 12, 2012 - Peer Reviewer 6 General The authors do not comment on the issue of cost which may play an important … The Draft Report does not appear to fully address this issue. … Judy (American Society of Echocardiography) General It would be remiss if we did not address the issue … The issue of microvascular disease in women could be expanded upon - for example, what is the prevalence … Peer Reviewer 5 Summary and Discussion 3) Is it appropriate to address the issue the performance
  4. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-health-systems-guidelines-development.pdf
    February 01, 2019 - Methods Research Report Improving Access To And Usability of Systematic Review Data for Health Systems Guideline Development Methods Research Report Improving Access to and Usability of Systematic Review Data for Health Systems Guidelines Development Methods Research Report …
  5. effectivehealthcare.ahrq.gov/sites/default/files/back-pain-treatment_disposition-comments.pdf
    February 29, 2016 - Spine: 01 February 2014 - Volume 39 - Issue 3 - p E182–E190) Thank you for this comment. … Continued use of these methods for NSLBP is unlikely to shed any new light on this issue or result … The issue with reporting of continuous and dichotomous outcomes is addressed in the “Limitations of … APTA would suggest the issue of multi-modal treatments be considered an issue of “Applicability” not … APTA would suggest the issue of multimodal treatments be considered an issue of Applicability not
  6. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0488_12-27-2011.pdf
    January 01, 2011 - Effective Health Care Topic Number: 0407 Document Completion Date: 02-14-12 1 Results of Topic Selection Process & Next Steps  Primary diagnosis and staging of pancreatic cancer will go forward for refinement as a systematic review. The scope of this topic, including populations, interventions, c…
  7. effectivehealthcare.ahrq.gov/sites/default/files/pdf/epilepsy-medicine_research-protocol.pdf
    February 01, 2008 - In addition to traditional adverse effects, fertility is also an issue with some agents causing teratogenicity … or inferior 12-month remission rates as compared to older antiepileptics.28,29 Another important issue … effectiveness review of the efficacy, safety and tolerability of antiepileptic medications and to address the issue
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/grading.ppt
    January 01, 2010 - Related Issue of Applicability* *See the “Assessing Applicability” module Related Issue of Applicability … being measured, other clinically important outcomes, the context of decisionmaking, whether the central issue
  9. effectivehealthcare.ahrq.gov/sites/default/files/pdf/colon-cancer-gene-profiling_technical-brief.pdf
    December 01, 2012 - As noted above, none of the studies described the important issue of clinical utility with use of the … While Key Informants agreed this was both an important clinical issue and an active research question

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