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  1. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0002_03-04-2008.pdf
    January 01, 2008 - Effective Health Care Topic Number(s): 0080 Document Completion Date: 11-24-09 1 Results of Topic Selection Process & Next Steps  Blood glucose control was found to be addressed by several recent systematic reviews and meta- analyses. However, many questions remain, particularly about patient…
  2. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-2007_executive.pdf
    January 01, 2007 - Cohort studies are needed to explore the issue of macular edema further.
  3. effectivehealthcare.ahrq.gov/sites/default/files/pdf/pediatric-ehr_research-protocol.pdf
    January 01, 2014 - pediatric-EHR-protocol-140818 Source: www.effectivehealthcare.ahrq.gov Published online: Augusts 18, 2014 Evidence-based Practice Center Technical Brief Protocol Core Functionality for Pediatric Electronic Health Records I. Background and Objectives for the Technical Brief Clinicians, informaticians, p…
  4. effectivehealthcare.ahrq.gov/sites/default/files/interactive_media_glasgow_presentation.pdf
    January 01, 2009 - Glasgow.Presentation   Source:    Eisenberg  Center  Conference  Series  2009,  Translating  Information  Into  Action:  Improving  Quality  of   Care  Through  Interactive  Media,  Effective  Health  Care  Program  Web  site   (http://www.effectivehealthcare.ahrq.g…
  5. effectivehealthcare.ahrq.gov/sites/default/files/pdf/plasma-cell-dyscrasias-sflc-assay_research-protocol.pdf
    May 02, 2011 - Variability of the SFLC assay is also an important issue with direct relevance to patient care. … evidence of the comparative effectiveness of this test in different settings may help elucidate the issue
  6. effectivehealthcare.ahrq.gov/sites/default/files/pdf/major-depressive-disorder_research-protocol.pdf
    November 24, 2014 - of greater benefit of pharmacotherapy for more severely depressed patients, an important clinical issue … psychotherapy, CAM interventions, or exercise as potential monotherapy for patients with mild MDD; a related issue
  7. effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-radiation_technical-brief.pdf
    November 01, 2009 - This is not true in the case of light ions such as carbon ions, (although it is less of an issue with
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-update_disposition-comments.pdf
    October 07, 2011 - recent report on higher cancer rates with ARBs vs ACE clinical trials [The Lancet Oncology, Volume 11, Issue … In light of AHRQ’s key questions, We agree – as noted in response to other reviewers raising this issue
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/selecting-evidence.ppt
    January 01, 2010 - Confounding by indication is not much of an issue for unexpected or unpredictable harms, so observational … Unpublished Trials To Assess Harms Using Data From Unpublished Supplemental Trials To Assess Harms The issue
  10. effectivehealthcare.ahrq.gov/sites/default/files/selecting-evidence.ppt
    January 01, 2010 - Confounding by indication is not much of an issue for unexpected or unpredictable harms, so observational … Unpublished Trials To Assess Harms Using Data From Unpublished Supplemental Trials To Assess Harms The issue
  11. 8 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-harms_methods.pdf
    November 01, 2008 - For unexpected adverse events, for example, confounding by indication may not be as important an issue
  12. 8 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/methodsguide_chou_assessing_harms_when_comparing.pdf
    November 01, 2008 - For unexpected adverse events, for example, confounding by indication may not be as important an issue
  13. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-health-systems-guidelines-development.pdf
    February 01, 2019 - Methods Research Report Improving Access To And Usability of Systematic Review Data for Health Systems Guideline Development Methods Research Report Improving Access to and Usability of Systematic Review Data for Health Systems Guidelines Development Methods Research Report …
  14. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0488_12-27-2011.pdf
    January 01, 2011 - Effective Health Care Topic Number: 0407 Document Completion Date: 02-14-12 1 Results of Topic Selection Process & Next Steps  Primary diagnosis and staging of pancreatic cancer will go forward for refinement as a systematic review. The scope of this topic, including populations, interventions, c…
  15. effectivehealthcare.ahrq.gov/sites/default/files/pdf/epilepsy-medicine_research-protocol.pdf
    February 01, 2008 - In addition to traditional adverse effects, fertility is also an issue with some agents causing teratogenicity … or inferior 12-month remission rates as compared to older antiepileptics.28,29 Another important issue … effectiveness review of the efficacy, safety and tolerability of antiepileptic medications and to address the issue
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/grading.ppt
    January 01, 2010 - Related Issue of Applicability* *See the “Assessing Applicability” module Related Issue of Applicability … being measured, other clinically important outcomes, the context of decisionmaking, whether the central issue
  17. effectivehealthcare.ahrq.gov/sites/default/files/pdf/colon-cancer-gene-profiling_technical-brief.pdf
    December 01, 2012 - As noted above, none of the studies described the important issue of clinical utility with use of the … While Key Informants agreed this was both an important clinical issue and an active research question
  18. effectivehealthcare.ahrq.gov/sites/default/files/pdf/assessing-the-risk-of-bias-in-systematic-reviews-of-health-care-interventions-01_0.pdf
    May 01, 2005 - implement protocols that have minimal concordance with practice, the discrepancy may be considered an issue … In such instances, an important issue is establishing an association between the event and the intervention
  19. effectivehealthcare.ahrq.gov/sites/default/files/back-pain-treatment_disposition-comments.pdf
    February 29, 2016 - Spine: 01 February 2014 - Volume 39 - Issue 3 - p E182–E190) Thank you for this comment. … Continued use of these methods for NSLBP is unlikely to shed any new light on this issue or result … The issue with reporting of continuous and dichotomous outcomes is addressed in the “Limitations of … APTA would suggest the issue of multi-modal treatments be considered an issue of “Applicability” not … APTA would suggest the issue of multimodal treatments be considered an issue of Applicability not
  20. effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/assessing-the-risk-of-bias-in-systematic-reviews-of-health-care-interventions-01.pdf
    May 01, 2005 - implement protocols that have minimal concordance with practice, the discrepancy may be considered an issue … In such instances, an important issue is establishing an association between the event and the intervention

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