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121. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/musculoskeletal-complaints-tests-children_research-protocol.pdf
     September 29, 2010 - cartilage, bone and soft tissues, and may lead to severe disability and functional loss, and, in rare instances

122. The Incident User Design in Comparative Effectiveness Research | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/incident-user-design/research
     May 15, 2012 - In some instances, stricter definitions of incident use may require multi-center studies to achieve adequate … In some instances, the numbers of incident users available even after pooling available databases may

123. DEcIDE 32: The Incident User Design in Comparative Effectiveness Research (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/incident-user-design_research.pdf
     May 01, 2012 - In some instances, stricter definitions of incident use may require multi-center studies to achieve … In some instances, the numbers of incident users available even after pooling available databases may

124. Evidence-based Practice Center Systematic Review Protocol - Management of Infantile Epilepsies (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-252-infantile-epilepsies-disposition-comments.pdf
     October 25, 2022 - Evidence-based Practice Center Systematic Review Protocol - Management of Infantile Epilepsies Comparative Effectiveness Review Disposition of Comments Report Research Review Title: Management of Infantile Epilepsies Draft report available for public comment from July 23, 2021, to September 6, …

125. Patient and Provider Level Strategies to Address Racial/Ethnic Disparities in Health and Healthcare (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/tech-brief-patient-provider-strategies-protocol-final.pdf
     May 18, 2022 - Patient and Provider Level Strategies to Address Racial/Ethnic Disparities in Health and Healthcare Evidence-based Practice Center Technical Brief Protocol Project Title: Patient and Provider Level Strategies to Address Racial/Ethnic Disparities in Health and Healthcare I. Background and Objectives…

126. Disposition of Comments for Treatment of Glaucoma: Comparative Effectiveness (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/glaucoma-treatment_disposition-comments.pdf
     April 01, 2012 - In some instances it can take between six months to ten years to discover an adverse event associated

127. Outcomes of Serious Mental Illness | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/mental-illness-outcomes/research-protocol
     March 03, 2014 - In instances where evidence from empirical studies informs the response, we will first provide a summary

128. serious-mental-illness-outcomes-140303 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/mental-illness-outcomes_research-protocol.pdf
     March 03, 2014 - In instances where evidence from empirical studies informs the response, we will first provide a summary

129. Comparative Effectiveness of Adjunctive Devices to Remove Thrombi or Protect Against Distal Embolization in Patients with Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention of Native Vessels (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/acs-pci-adjunctive-devices_disposition-comments.pdf
     March 01, 2012 - positive outcome, please consider replacing “increased risk” with something like “favors device” All instances

130. Ch 4-User-Guide-To-Ocer 130129 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/ch_4-user-guide-to-ocer_130129.pdf
     January 01, 2010 - 45 Abstract Characterization of exposure is a central issue in the analysis of observational data; however, no “one size fits all” solution exists for exposure measurement. In this chapter, we discuss potential exposure measurement approaches for observational comparative effectiveness research (CER). First, it is …

131. M (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/systematicreviewsreplacedenovo.pdf
     September 01, 2009 - Although EPCs could use this definition in most instances, they may need to tailor criteria for specific

132. M (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-de-novo-processes_methods.pdf
     September 01, 2009 - Although EPCs could use this definition in most instances, they may need to tailor criteria for specific

133. Disposition of Comments Report for Primary Care Management of Abnormal Uterine Bleeding (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/abnormal-uterine-bleeding_disposition-comments.pdf
     March 21, 2013 - They are included only in instances in which the formulation that is not available was a comparison

134. White Paper: Narratively Describing Effects of Interventions in Systematic Reviews (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/white-paper-roadmap-interventions.pdf
     November 01, 2020 - important difference [MCID] of a scale5 defined as an effect noticeable to the individual), but in other instances

135. Tympanostomy Tubes in Children With Otitis Media (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/tympanostomy-tubes-executive-170523.pdf
     May 01, 2017 - ) No precautions All Participants 46/82 (56.1) [reference] Ear plugs Children who each had ≥ 125 instances … of water exposure 29/39 (74.3) 2.69 (0.95 – 7.64) No precautions Children who each had ≥ 125 instances

136. Imaging for Pretreatment Staging of Small Cell Lung Cancer | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/lung-cancer-staging/research-protocol
     December 08, 2014 - Redundancy: To avoid double-counting patients, in instances in which several reports of the same or overlapping … that in some situations exclusion of non-English studies could lead to bias, we believe that the few instances

137. Cancer-Pancreas Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-pancreas_executive.pdf
     September 01, 2014 - Redundancy: To avoid double-counting patients, in instances in which several reports of the same or overlapping … that in some situations exclusion of non-English studies could lead to bias, we believe that the few instances

138. Single-arm studies in comparative effectiveness reviews (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/single-group-studies_white-paper.pdf
     January 01, 2013 - However, there are many instances where even observational studies with a comparison group are unavailable … In these instances, comparisons are extrapolations based on expected outcomes in the ―missing‖ comparison

139. S77 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/s77.pdf
     October 01, 2007 - ORIGINAL ARTICLE Out-of-Pocket Pharmacy Expenditures for Veterans Under Medicare Part D Randall W. Rupper, MD, MPH,*†‡ Byron D. Bair, MD,*‡ Brian C. Sauer, PhD,†‡ Jonathan R. Nebeker, MD, MS,*†‡ Judith Shinogle, PhD,§¶ and Matthew Samore, MD†‡ Objectives: Because the VA pharmacy benefit is deemed equivalent coverage…

140. Evidence Summary-Comparative-Effectiveness-Review-213-Lower-Limb-Prostheses (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-213-lower-limb-protheses-evidence-summary.pdf
     September 01, 2018 - patients to prostheses relies heavily on performance-based assessments, self-assessments, and, in some instances … However, we recognize that it will remain common that unvalidated measures may be appropriate in select instances