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1. Improving the Utility of Evidence Synthesis for Decision Makers in the Face of Insufficient Evidence | Effective Health Care (EHC) Program
   effectivehealthcare.ahrq.gov/products/improving-evidence-synthesis/white-paper
   April 16, 2021 - In the purposive sample of 43 systematic reviews, the use of the term "insufficient" covered both instances … of no evidence and instances of evidence being present but insufficient to estimate an effect.

2. Evidence Summary: Comparative Effectiveness Review No. 245_Breast Reconstruction After Mastectomy: A Systematic Review and Meta-Analysis (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/cer-245-breast-reconstruction-after-mastectomy-evidence-summary-updated.pdf
   July 01, 2021 - outcomes, ▲▲ = Moderate SoE of better clinical outcomes, ▲▲▲ = High SoE of better clinical outcomes (no instances … complications, ◆◆ = Moderate SoE of increased complications, ◆◆◆ = High SoE of increased complications (no instances … comparable outcomes, ~~ = Moderate SoE of comparable outcomes, ~~~ = High SoE of comparable outcomes (no instances … i.e., outcome not applicable to KQ) Colors: Insufficient SoE, Low SoE, Moderate SoE, High SoE (no instances

3. Evidence Summary: Comparative Effectiveness Review No. 245_Breast Reconstruction After Mastectomy: A Systematic Review and Meta-Analysis (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/cer-245-breast-reconstruction-after-mastectomy-evidence-summary_0.pdf
   July 01, 2021 - outcomes, ▲▲ = Moderate SoE of better clinical outcomes, ▲▲▲ = High SoE of better clinical outcomes (no instances … complications, ◆◆ = Moderate SoE of increased complications, ◆◆◆ = High SoE of increased complications (no instances … comparable outcomes, ~~ = Moderate SoE of comparable outcomes, ~~~ = High SoE of comparable outcomes (no instances … i.e., outcome not applicable to KQ) Colors: Insufficient SoE, Low SoE, Moderate SoE, High SoE (no instances

4. Evidence Summary: Comparative Effectiveness Review No. 245_Breast Reconstruction After Mastectomy: A Systematic Review and Meta-Analysis (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/cer-245-breast-reconstruction-after-mastectomy-evidence-summary-updated-1.pdf
   October 01, 2021 - outcomes, ▲▲ = Moderate SoE of better clinical outcomes, ▲▲▲ = High SoE of better clinical outcomes (no instances … complications, ◆◆ = Moderate SoE of increased complications, ◆◆◆ = High SoE of increased complications (no instances … comparable outcomes, ~~ = Moderate SoE of comparable outcomes, ~~~ = High SoE of comparable outcomes (no instances … i.e., outcome not applicable to KQ) Colors: Insufficient SoE, Low SoE, Moderate SoE, High SoE (no instances

5. Care Interventions for People Living With Dementia and Their Caregivers | Effective Health Care (EHC) Program
   effectivehealthcare.ahrq.gov/products/care-interventions-pwd/report
   August 31, 2020 - informal caregiver quality of life at 6 months was reported as “low” rather than “insufficient” in five instances … These instances have been corrected. In addition, two references were added.

6. Knowledge Brief #1 Public Deliberation on Health Topics (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/pdf/deliberative-methods_research.pdf
   February 01, 2013 - In other instances, participants in public deliberation have been asked explicitly to provide guidance … In the United States, many instances have been research projects sponsored by foundations or academic … In contrast, several instances of deliberation outside the United States dealt with how to handle new … In some instances, core values, such as equity and freedom of choice, were pitted against one another

7. Comparative Effectiveness of Fecal DNA Testing in Screening for Colorectal Cancer in Average Risk Adults. (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-cancer-screening_disposition-comments.pdf
   February 01, 2012 - We have corrected all instances of SIP request to Exact Sciences. … We have corrected all instances of SIP request to Exact Sciences. … We have corrected all instances of SIP request to Exact Sciences. … We have corrected all instances of SIP request to Exact Sciences. … We have corrected all instances of SIP request to Exact Sciences.

8. Models of Cancer Survivorship Care | Effective Health Care (EHC) Program
   effectivehealthcare.ahrq.gov/products/cancer-survivor-care-transition/technical-brief
   March 18, 2014 - Although competing considerations and incentives may lead oncologists or oncology providers in many instances

9. Evidence Summary: Comparative Effectiveness Review No. 236 Maternal, Fetal, and Child Outcomes of Mental Health Treatments in Women: A Systematic Review of Perinatal Pharmacologic Interventions (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/cer-236-mental-health-pregnancy-evidence-summary.pdf
   April 01, 2021 - In many instances, controls for confounding reduced the effect size and, in some instances, reversed

10. Correcting for Publication Bias in the Presence of Covariates | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/publication-bias/research
    September 16, 2011 - Correcting for Publication Bias in the Presence of Covariates Research Report September 16, 2011 Web Version [NLM Site] Download Main Document PDF 2.1 MB People using assistive technology may not be able to fully access information in this file. For additional assistance, please contact us . Structur…

11. Medication Therapy Management Interventions in Outpatient Settings | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/medication-therapy-management/research
    November 17, 2014 - In a few instances, described below, the evidence led us to conclude benefit or lack of benefit.

12. Executive Summary_Comparative Effectiveness Review No. 261_Postpartum Care up to 1 Year After Pregnancy: A Systematic Review and Meta-Analysis (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-261-postpartum-care-executive-summary.pdf
    June 01, 2023 - better utilization or clinical outcomes, ▲▲▲ = High SoE of better utilization or clinical outcomes (no instances … comparable outcomes, ~~ = Moderate SoE of comparable outcomes, ~~~ = High SoE of comparable outcomes (no instances … strength of evidence (pink), Moderate strength of evidence (blue), High strength of evidence (green) (no instances

13. Executive Summary_Comparative Effectiveness Review No. 263: Management of Postpartum Hypertensive Disorders of Pregnancy (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-263-postpartum-hypertensive-pregnancy-executive-summary.pdf
    May 01, 2023 - Shorter duration regimens may result in fewer instances of magnesium-related toxicities (as manifested … = strength of evidence, XR = extended release ✓ = Low SoE, ✓✓ = Moderate SoE, ✓✓✓ = High SoE (no instances … in this table) Color legend: High strength of evidence (green) (no instances in this table), Moderate

14. Disposition of Comments: CER 230 Therapies for Clinically Localized Prostate Cancer (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/cer-230-prostate-cancer-comments.pdf
    September 17, 2020 - • In several instances, reviewers requested additional information about study inclusion criteria

15. Evaluation of the AHRQ Healthcare Horizon Scanning System | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/horizon-scan/research
    May 26, 2016 - Evaluation of the AHRQ Healthcare Horizon Scanning System Research Report May 26, 2016 Download Main Document PDF 2.4 MB This report is available in PDF (2.5 MB) only. People using assistive technology may not be able to fully access information in this file. For additional assistance, please contact…

16. Bayesian Approaches to Indirect Comparisons | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/indirect-comparisons/abstract
    September 22, 2011 - Bayesian Approaches to Indirect Comparisons Abstract September 22, 2011 Topic Abstract Introduction: Systematic reviews are a primary synthesis of evidence for healthcare decision makers confronted with questions about the comparative effectiveness and safety of interventions. The strength and useful…

17. What is the comparative effectiveness of genetic and other diagnostic tests to identify and treat intellectual and developmental disabilities caused by genetic mutations in post-natal to early childhood populations? | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/get-involved/nominated-topics/what-is-the-comparative-effectiveness-of-genetic-and-other-diagnostic-tests-to-identify-and-treat-intellectual-and-developmental-disabilities-caused-by-genetic-mutations-in-post-natal-to-early-childhood-populations
    October 26, 2012 - We feel that in many instances it is abuse of the Medicaid system and has little to no clinical utility

18. Integrating Health System Data With Systematic Reviews_Methods Research Report (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-research-report-integrating-health-system-data.pdf
    April 01, 2020 - In most instances, these examples were explicit about their rationale for incorporating unpublished … outcomes, and local health system data provided longer- term outcomes on total pancreatectomy. 6 • In two instances … local data were used to determine applicability of published data to the health system.7, 8 In some instances … review is being conducted to expand the evidence base and improve the strength of evidence, i.e., instances … Systematic Reviews To Support Healthcare Decision Making Even though the health system data can, in some instances

19. Chicago-Area DEcIDE Center (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/off-label-use-research-priorities_research.pdf
    May 01, 2009 - In general, there were only rare instances in which a drug identified as lacking strong evidence in … Given limitations of both ICD-9 and DRUGDEX diagnostic labels, there were many instances in which there … For these two instances, the most frequent specific codes suggested this interpretation. … In several instances among atypical antipsychotics, the most common off-label use is more frequent than … Although NDTI links a drug’s use to a clinical condition, this feature may not account for instances

20. Developing Evidence-Based Research Priorities for Off-Label Drug Use | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/off-label-use-research-priorities/research
    June 29, 2009 - In general, there were only rare instances in which a drug identified as lacking strong evidence in DRUGDEX … Given limitations of both ICD-9 and DRUGDEX diagnostic labels, there were many instances in which there … For these two instances, the most frequent specific codes suggested this interpretation. … In several instances among atypical antipsychotics, the most common off-label use is more frequent than … Although NDTI links a drug’s use to a clinical condition, this feature may not account for instances