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101. Making Healthcare Safer IV Rapid Response_Active Surveillance Culturing of Clostridioides difficile and Multidrug-Resistant Organisms: Methicillin-Resistant Staphylococcus aureus, Carbapenem-Resistant Enterobacterales, and Candida auris (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs4-active-infection-rapid-response.pdf
     May 01, 2024 - Interestingly, the risk of any S. aureus infection (including methicillin- sensitive infections) was … /prevention and control[majr] OR "healthcare acquired infection"[ti] OR "healthcare acquired infections … "[ti] OR "healthcare associated infection"[ti] OR "healthcare associated infections"[ti] OR "hospital … acquired infection"[ti] OR "hospital acquired infections"[ti] OR "hospital associated infection"[ti … "nosocomial infection"[ti] OR "nosocomial infections"[ti] OR "nosocomial outbreak"[ti] OR "nosocomial

102. Tonsillectomy for Obstructive Sleep-Disordered Breathing or Recurrent Throat Infection in Children (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/tonsillectomy_executive.pdf
     January 01, 2017 - Effectiveness of Tonsillectomy for Recurrent Throat Infection Although studies assessed numbers of infections … infection confirmed. … proportion of infections in retrospective cohort and significantly more infections in nonsurgical … of reported infections, and few reported culture-confirmed bacterial infections. … Indeed the literature lacks a consistent, consensus definition of 25 infection; defining infection

103. Research Protocol: Clostridium difficile Infection Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/c-difficile-update_research-protocol.pdf
     December 23, 2014 - Unfortunately, protocols for targeted hospital acquired infections are not always congruent. … Available at: http://effectivehealthcare.ahrq.gov/ehc/asset s/File/c-diff-infections-nomination- 140925 … Renewed interest in a difficult disease: Clostridium difficile infections--epidemiology and current … Guidelines for diagnosis, treatment, and prevention of Clostridium difficile infections. … Strategies to prevent clostridium difficile infections in acute care hospitals.

104. Research Review Title: Infection Prevention and Control for the Emergency Medical Services and 911 Workforce (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ems-911-workforce-disposition-comments.pdf
     November 01, 2022 - The vast majority (29/30) of provider-level infections that occurred during the study period were deemed … and exposure investigation practices (Murphy et al, 2020) in preventing COVID-19 infections, in that … Additionally, the current messaging suggests the futility of PPE, yet only 3% of infections (one of … We also acknowledged that it was challenging to determine whether COVID-19 infections in EMS providers … also acknowledged that it was challenging to determine from the published studies whether COVID-19 infections

105. Update Topic CER 31 Clostridium difficile NSD FINAL (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/c-diff-infections-nomination-140925.pdf
     February 19, 2014 - Effectiveness of Early Diagnosis, Prevention, and Treatment of Clostridium difficile Infection … Effectiveness of Early Diagnosis, Prevention, and Treatment of Clostridium difficile (C. difficile) Infection … Effectiveness of Early Diagnosis, Prevention, and Treatment of Clostridium difficile Infection. … different methods for detection of toxigenic C. difficile to assist with diagnosis of C. difficile infection … (CDI) is one of the most common hospital-acquired infections (HAIs).

106. Health Facilities | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/health-topics/health-facilities
     November 15, 2011 - October 22, 2012 Future Research Needs for Prevention and Treatment of Clostridium difficile Infection … February 13, 2014 Environmental Cleaning for the Prevention of Healthcare-Associated Infections … Archived August 10, 2015 Environmental Cleaning for the Prevention of Healthcare-Associated Infections … Paper September 30, 2011 Effectiveness of Screening and Treatment of C. difficile Infections … , 2010 Effectiveness of Early Diagnosis, Prevention, and Treatment of Clostridium difficile Infection

107. Antibody Response Following SARS-CoV-2 Infection and Implications for Immunity: Final Update of a Rapid, Living Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/version-3-immunity-after-COVID-19.pdf
     December 31, 2022 - wider availability of nucleic acid amplification tests (NAATs) and antigen tests to diagnose recent infections … that protection against symptomatic reinfection may be slightly less for individuals whose initial infections … study relied on frequent symptom surveys rather than routine surveillance with a NAAT to detect new infections … Unvaccinated: 107 days (3.5 months) Unvaccinated: 164 days (5.5 days) Delta (99.93% of all infections … Emerging Microbes & Infections. 2022 2022/12/31;11(1):793-803. doi: http://dx.doi.org/10.1080/22221751.2022.204644

108. Digestive Diseases | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/health-topics/digestive-diseases
     May 20, 2013 - Review Research Protocol Archived March 14, 2012 Treatment of Hepatitis C Virus Infection … Needs Systematic Review Archived April 15, 2013 Treatment for Hepatitis C Virus Infection … Dyscrasias Systematic Review Archived August 23, 2012 Screening for Hepatitis C Virus Infection … Archived March 13, 2012 Effectiveness of Screening and Treatment of C. difficile Infections … 2006 Report Research Protocol Archived August 5, 2010 Clostridium difficile Infection

109. Procalcitonin-Guided Antibiotic Therapy | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/procalcitonin/research
     October 05, 2012 - procalcitonin in the clinical management of adult and pediatric patients with suspected local or systemic infection … in adult ICU patients and to initiate or discontinue antibiotics in patients with respiratory tract infections … patients with the following conditions: pregnancy; absolute neutropenia; immunocompromised states; chronic infections … , and infections for which prolonged antibiotic therapy is standard of care (e.g., infective endocarditis … in adult ICU patients and to initiate or discontinue antibiotics in patients with respiratory tract infections

110. Procalcitonin for Diagnosis and Management of Sepsis | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/procalcitonin/research-protocol
     April 26, 2011 - biomarker for infection, but its exact utility in diagnosing and managing patients with suspected infections … sepsis, urinary tract infections, and meningitis. … site infection Osteomyelitis Systemic infections Neutropenic fever Bacteremia Sepsis Septic … : Local infections Pneumonia Urinary tract infection Meningitis Systemic infections Neutropenic … '/exp OR 'postoperative infections'/exp OR 'postoperative complications'/exp OR 'post-surgical infection

111. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/procalcitonin_research-protocol.pdf
     September 08, 2011 - sepsis, urinary tract infections, and meningitis. …  Surgical site infection  Osteomyelitis o Systemic infections  Neutropenic fever Source … infection  Meningitis o Systemic infections  Neutropenic fever  Bacteremia  Sepsis  … , local bleeding or infection) Adverse events of therapy (persistent or recurrent infection, … '/exp OR 'postoperative infections'/exp OR 'postoperative complications'/exp OR 'post-surgical infection

112. Rapid Evidence Product: No-Touch Modalities for Disinfecting Patient Rooms in Acute Care Settings (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/rapid-review-no-touch-modalities.pdf
     May 01, 2022 - Environmental cleaning for the prevention of healthcare-associated Infections. … Search Strategy: ─ #1 cross infection[mh] OR hospital infection*[tiab] OR health care acquired infection … *[tiab] OR health care associated infection*[tiab] OR hospital acquired infection*[tiab] OR hospital … difficile infections (CDIs) decreased. … rate due to central-line- associated bloodstream infections and catheter-associated urinary tract infections

113. Version-3-Immunity-After-Covid-19-Appendix-Table-B-1 (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/version-3-immunity-after-COVID-19-appendix-table-B-1.xlsx
     January 24, 2022 - Comorbidities, N (%) Assay Type Assay Brand Definition of a positive test Frequency of Ab testing Primary infections … Male Sex/Gender, N (%) Comorbidities, N (%) Assay Type Assay Brand Frequency of Ab testing Primary infections … infection requiring hospitalization) Primary infections, N (%) Total: 2747 Symptomatic: 2041 (74)* … against repeat infections was calculated as 1 minus the ratio of infection rate for the initially positive … The prevalence of infections classified as symptomatic or asymptomatic was compared for primary infections

114. Colonic Diseases | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/health-topics/colonic-diseases
     April 02, 2014 - Archived March 13, 2012 Effectiveness of Screening and Treatment of C. difficile Infections … s Disease Research Protocol Archived September 1, 2010 Clostridium difficile Infection

115. EHC Protocol: Addressing Social Isolation To Improve Health of Older Adults: A Rapid Evidence Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/making-healthcare-safer-IV.pdf
     August 04, 2023 - What is the frequency and severity of harms associated with healthcare associated infections and asymptomatic … safety measures or indicators have been used to examine the harm associated with healthcare associated infections … In the United States, more than 2.8 million antimicrobial-resistant infections occur each year and … patients for MRSA, CRE, C.auris, and C.difficile that focus on healthcare associated infections or … Strategies to prevent Clostridioides difficile infections in acute-care hospitals: 2022 update.

116. Rapid Evidence Product: Masks for Prevention of COVID-19 in Community and Healthcare Settings Version 2 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/rapid-review-masks-prevention-covid-version-2.pdf
     December 01, 2021 - evidence about the use of facemasks and effects on risk of other respiratory infections, including … symptoms found no difference between an N95 versus surgical mask in risk of infections. … with SARS-CoV-2, 15 studies on risk of infection with SARS-CoV-1, and one study on risk of infections … Probable secondary infections in households of SARS patients in Hong Kong. … Probable secondary infections in households of SARS patients in Hong Kong.

117. Environmental, Clinical and Economic Outcomes of Hospital Resources to Prevent Hospital-Acquired Infections (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/prevent-hai-protocol.pdf
     April 16, 2024 - Environmental, Clinical and Economic Outcomes of Hospital Resources to Prevent Hospital-Acquired Infections … : Environmental, Clinical and Economic Outcomes of Hospital Resources to Prevent Hospital-Acquired Infections … devices and items used only once are often promoted as a means to reduce the risk of hospital-acquired infections … Publication type English language For primary interest interventions (devices/items used to prevent infections … Title: Environmental, Clinical and Economic Outcomes of Hospital Resources to Prevent Hospital-Acquired Infections

118. Masks for Prevention of COVID-19 in Community and Healthcare Settings (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/rapid-review-masks-prevention-covid-version-1.pdf
     December 01, 2021 - evidence about the use of facemasks and effects on risk of other respiratory infections, including … symptoms found no difference between an N95 versus surgical mask in risk of infections. … study evaluated masks’ effects on risk of infections with MERS-CoV (Appendix Table B-3). … Probable secondary infections in households of SARS patients in Hong Kong. … Probable secondary infections in households of SARS patients in Hong Kong.

119. Procalcitonin Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/procalcitonin_executive.pdf
     October 01, 2012 - levels rising at the onset of infection and falling rapidly as the infection resolves, as compared … The cutoff level of procalcitonin to identify postoperative patients with infection or at risk of infection … , or at risk of infection. … or unlikely to have infection as compared with those with proven or probable infection. … Patients with chronic infections and infections for which a longer duration of antibiotic therapy

120. Infection Prevention and Control for the Emergency Medical Services/911 Workforce (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/ems-911-workforce-technical-brief_0.pdf
     March 10, 2022 - Moderate evidence exists on the epidemiology of infections and effectiveness of IPC practices in EMS … • Most research since 2006 has concentrated on the epidemiology of infections and infection risk … None of the studies reported on severity of infections other than SARS-CoV2. Table 3. … Guide to Infection Prevention in Emergency Medical Services Association for Professionals in Infection … Infection Control in Healthcare Personnel: Infrastructure and Routine Practices for Occupational Infection