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261. Facts and Figures Exhibit 5.10
     hcup-us.ahrq.gov/reports/factsandfigures/2007/exhibit5_10.jsp
     January 01, 2007 - 12.8 42 Infectious and parasitic 178 186‡ 100.0 100.0 5 Septicemia (blood infection … Skin and subcutaneous tissue 124 202 100.0 100.0 63 Skin and subcutaneous tissue infections … Anemia and skin and subcutaneous tissue infections each increased 76 percent.

262. Nis 2014 Maskedstats Core (pdf file)
     hcup-us.ahrq.gov/db/nation/nis/tools/stats/NIS_2014_MaskedStats_Core.PDF
     January 01, 2014 - W MCC 528 0.01% 486: KNEE PROCEDURES W PDX OF INFECTION W CC 1,466 0.02% 487: KNEE PROCEDURES W PDX … OF INFECTION W/O CC/MCC 788 0.01% 488: KNEE PROCEDURES W/O PDX OF INFECTION W CC/MCC 1,960 0.03% 489 … : KNEE PROCEDURES W/O PDX OF INFECTION W/O CC/MCC 3,044 0.04% 490: BACK & NECK PROC EXC SPINAL FUSION … ; unspecified site 1,422 0.02% 4: Mycoses 4,706 0.07% 5: HIV infection 7,078 0.10% 6: Hepatitis 9,279 … 0.13% 7: Viral infection 12,389 0.18% 8: Other infections; including parasitic 3,334 0.05% 9: Sexually

263. Nis 2014 Maskedstats Core Weighted (pdf file)
     hcup-us.ahrq.gov/db/nation/nis/tools/stats/NIS_2014_MaskedStats_Core_Weighted.PDF
     January 01, 2014 - W MCC 2,640 0.01% 486: KNEE PROCEDURES W PDX OF INFECTION W CC 7,330 0.02% 487: KNEE PROCEDURES W … PDX OF INFECTION W/O CC/MCC 3,940 0.01% 488: KNEE PROCEDURES W/O PDX OF INFECTION W CC/MCC 9,800 0.03% … 489: KNEE PROCEDURES W/O PDX OF INFECTION W/O CC/MCC 15,220 0.04% please refer to the section on … ; unspecified site 7,110 0.02% 4: Mycoses 23,530 0.07% 5: HIV infection 35,390 0.10% 6: Hepatitis … 46,395 0.13% 7: Viral infection 61,945 0.18% 8: Other infections; including parasitic 16,670 0.05%

264. Nis 2013 Maskedstats Core (pdf file)
     hcup-us.ahrq.gov/db/nation/nis/tools/stats/NIS_2013_MaskedStats_Core.PDF
     January 01, 2013 - & LIMB REATTACHMENT PROC OF UPPER EXTREMITY W/O CC/MCC 10,083 0.14% 485: KNEE PROCEDURES W PDX OF INFECTION … W CC 1,455 0.02% 487: KNEE PROCEDURES W PDX OF INFECTION W/O CC/MCC 789 0.01% 488: KNEE PROCEDURES … W/O PDX OF INFECTION W CC/MCC 1,910 0.03% 489: KNEE PROCEDURES W/O PDX OF INFECTION W/O CC/MCC 3,273 … ; unspecified site 1,460 0.02% 4: Mycoses 4,865 0.07% 5: HIV infection 7,394 0.10% 6: Hepatitis 9,459 … 0.13% 7: Viral infection 12,491 0.18% 8: Other infections; including parasitic 3,595 0.05% 9: Sexually

265. Maskedstats Nrd 2016 Core (pdf file)
     hcup-us.ahrq.gov/db/nation/nrd/stats/MaskedStats_NRD_2016_Core.PDF
     January 01, 2016 - JOINT/LIMB REATTACHMENT PROCEDURE OF UPPER EXTREMITIES 56,817 0.33% 485: KNEE PROCEDURES W PDX OF INFECTION … W MCC 928 0.01% 486: KNEE PROCEDURES W PDX OF INFECTION W CC 2,500 0.01% 487: KNEE PROCEDURES W PDX … OF INFECTION W/O CC/MCC 1,283 0.01% 488: KNEE PROCEDURES W/O PDX OF INFECTION W CC/MCC 4,655 0.03% … 489: KNEE PROCEDURES W/O PDX OF INFECTION W/O CC/MCC 5,838 0.03% 492: LOWER EXTREM & HUMER PROC EXCEPT … PROC W CC 16,535 0.10% 858: POSTOPERATIVE OR POST-TRAUMATIC INFECTIONS W O.R.

266. Maskedstats Nrd 2019 Core V2 (pdf file)
     hcup-us.ahrq.gov/db/nation/nrd/stats/MaskedStats_NRD_2019_CORE_V2.PDF
     January 01, 2019 - JOINT/LIMB REATTACHMENT PROCEDURE OF UPPER EXTREMITIES 80,003 0.44% 485: KNEE PROCEDURES W PDX OF INFECTION … W MCC 1,705 0.01% 486: KNEE PROCEDURES W PDX OF INFECTION W CC 4,270 0.02% 487: KNEE PROCEDURES W … PDX OF INFECTION W/O CC/MCC 1,627 0.01% 488: KNEE PROCEDURES W/O PDX OF INFECTION W CC/MCC 5,679 0.03% … 489: KNEE PROCEDURES W/O PDX OF INFECTION W/O CC/MCC 6,151 0.03% 492: LOWER EXTREM & HUMER PROC EXCEPT … PROC W CC 18,852 0.10% 858: POSTOPERATIVE OR POST-TRAUMATIC INFECTIONS W O.R.

267. Facts and Figures Exhibit 2.5
     hcup-us.ahrq.gov/reports/factsandfigures/2009/exhibit2_5.jsp
     January 01, 2009 - 4% 64% Non-specific chest pain 39 78 2% 3% 99% Skin and subcutaneous tissue infections … (23 percent) of all stays for alcohol-related conditions and over 10 percent of all stays for skin infections … mood disorders (64 percent), non-specific chest pain (99 percent), and skin and subcutaneous tissue infections

268. HCUP Statistical Brief #12: Hospital Stays for Gastrointestinal Diseases, 2004 (pdf file)
     hcup-us.ahrq.gov/reports/statbriefs/sb12.pdf
     September 01, 2006 - ulcerative diverticulosis, appendici- orders of the esophagus, ive congenital anomalies, testinal infections … as ulcers, strictures, and gastroesophageal reflux disease or GERD), abdominal hernia, intestinal infections … esophagus – 13 Cancer of stomach – 14 Cancer of colon – 15 Cancer of rectum and anus – 135 Intestinal infection … 59.3% 0.5% 54 6 Abdominal hernia 181,400 4.5 $9,200 $1,615,332,700 35.0% 1.3% 59 7 Intestinal infections … colitis Diverticulosis Appendicitis Esophageal disorders Digestive congenital anomalies Intestinal infections

269. Statistical Brief #118: Hospital Stays for Children, 2009 (pdf file)
     hcup-us.ahrq.gov/reports/statbriefs/sb118.pdf
     August 01, 2011 - of the top 10 specific diagnoses over the last nine years were for skin and subcutaneous tissue infections … Five of the top 10 conditions are infections—pneumonia, bronchitis, skin infections, urinary tract infections … Skin and subcutaneous tissue infections 71,900 9.6 8. Epilepsy 70,200 9.4 9. … Urinary tract infections 48,100 6.5 10. Influenza 39,900 5.4 * Excludes newborn conditions. … Incision and drainage of skin and subcutaneous tissue—conducted primarily for infections—ranked 10th

270. Maskedstats Nrd 2017 Core (pdf file)
     hcup-us.ahrq.gov/db/nation/nrd/stats/MaskedStats_NRD_2017_Core.PDF
     January 01, 2017 - JOINT/LIMB REATTACHMENT PROCEDURE OF UPPER EXTREMITIES 65,057 0.36% 485: KNEE PROCEDURES W PDX OF INFECTION … W MCC 1,028 0.01% 486: KNEE PROCEDURES W PDX OF INFECTION W CC 2,970 0.02% 487: KNEE PROCEDURES W … PDX OF INFECTION W/O CC/MCC 1,287 0.01% 488: KNEE PROCEDURES W/O PDX OF INFECTION W CC/MCC 4,996 0.03% … 489: KNEE PROCEDURES W/O PDX OF INFECTION W/O CC/MCC 5,865 0.03% 492: LOWER EXTREM & HUMER PROC EXCEPT … PROC W CC 17,351 0.10% 858: POSTOPERATIVE OR POST-TRAUMATIC INFECTIONS W O.R.

271. Maskedstats Nis 2017 Core Weighted (pdf file)
     hcup-us.ahrq.gov/db/nation/nis/tools/stats/MaskedStats_NIS_2017_Core_Weighted.PDF
     January 01, 2017 - JOINT/LIMB REATTACHMENT PROCEDURE OF UPPER EXTREMITIES 118,620 0.33% 485: KNEE PROCEDURES W PDX OF INFECTION … W MCC 1,830 0.01% 486: KNEE PROCEDURES W PDX OF INFECTION W CC 5,495 0.02% 487: KNEE PROCEDURES W … PDX OF INFECTION W/O CC/MCC 2,305 0.01% 488: KNEE PROCEDURES W/O PDX OF INFECTION W CC/MCC 9,625 0.03% … 489: KNEE PROCEDURES W/O PDX OF INFECTION W/O CC/MCC 10,930 0.03% 492: LOWER EXTREM & HUMER PROC EXCEPT … PROC W CC 32,425 0.09% 858: POSTOPERATIVE OR POST-TRAUMATIC INFECTIONS W O.R.

272. Maskedstats Nis 2019 Core V2 (pdf file)
     hcup-us.ahrq.gov/db/nation/nis/tools/stats/MaskedStats_NIS_2019_Core_V2.PDF
     January 01, 2019 - JOINT/LIMB REATTACHMENT PROCEDURE OF UPPER EXTREMITIES 28,184 0.40% 485: KNEE PROCEDURES W PDX OF INFECTION … W MCC 597 0.01% 486: KNEE PROCEDURES W PDX OF INFECTION W CC 1,527 0.02% 487: KNEE PROCEDURES W PDX … OF INFECTION W/O CC/MCC 569 0.01% 488: KNEE PROCEDURES W/O PDX OF INFECTION W CC/MCC 2,037 0.03% 489 … : KNEE PROCEDURES W/O PDX OF INFECTION W/O CC/MCC 2,168 0.03% 492: LOWER EXTREM & HUMER PROC EXCEPT … PROC W CC 6,928 0.10% 858: POSTOPERATIVE OR POST-TRAUMATIC INFECTIONS W O.R.

273. Maskedstats Nis 2016 Core Weighted (pdf file)
     hcup-us.ahrq.gov/db/nation/nis/tools/stats/MaskedStats_NIS_2016_Core_Weighted.PDF
     January 01, 2016 - Frequency Distribution for DRG_NOPOA DRG_NoPOA Frequency Percent of Total 485: KNEE PROCEDURES W PDX OF INFECTION … W MCC 1,920 0.01% 486: KNEE PROCEDURES W PDX OF INFECTION W CC 5,100 0.01% 487: KNEE PROCEDURES W … PDX OF INFECTION W/O CC/MCC 2,365 0.01% 488: KNEE PROCEDURES W/O PDX OF INFECTION W CC/MCC 9,460 0.03% … 489: KNEE PROCEDURES W/O PDX OF INFECTION W/O CC/MCC 10,975 0.03% 492: LOWER EXTREM & HUMER PROC EXCEPT … PROC W CC 32,130 0.09% 858: POSTOPERATIVE OR POST-TRAUMATIC INFECTIONS W O.R.

274. Kid 2016 Maskedstats Core (pdf file)
     hcup-us.ahrq.gov/db/nation/kid/tools/stats/KID_2016_MaskedStats_Core.PDF
     January 01, 2016 - MAJOR JOINT/LIMB REATTACHMENT PROCEDURE OF UPPER EXTREMITIES 38 0.00% 485: KNEE PROCEDURES W PDX OF INFECTION … W MCC 11 0.00% 486: KNEE PROCEDURES W PDX OF INFECTION W CC 97 0.00% 487: KNEE PROCEDURES W PDX OF … INFECTION W/O CC/MCC 101 0.00% 488: KNEE PROCEDURES W/O PDX OF INFECTION W CC/MCC 379 0.01% 489: KNEE … PROCEDURES W/O PDX OF INFECTION W/O CC/MCC 891 0.03% please refer to the section on Description of … PROC W CC 905 0.03% 858: POSTOPERATIVE OR POST-TRAUMATIC INFECTIONS W O.R.

275. Emergency Department Visits for Children and Young Adults With Diabetes, 2012 #203
     hcup-us.ahrq.gov/reports/statbriefs/sb203-Emergency-Department-Children-Diabetes.jsp
     April 01, 2016 - Abdominal pain 31.2 5.3 3 30.2 6.7 3 1.0 0.7 - Skin and subcutaneous infections … Nausea and vomiting 15.2 2.6 7 14.8 3.3 6 0.4 0.3 - Other upper respiratory infection … Skin and subcutaneous infections and urinary tract infections were among the top 10 first-listed conditions … other top-ranking first-listed conditions were abdominal pain (6.7 percent), skin and subcutaneous infections … 181 Other complications of pregnancy 197 Skin and subcutaneous tissue infection

276. Most Frequent Conditions in U.S. Hospitals, 2010 (pdf file)
     hcup-us.ahrq.gov/reports/statbriefs/sb148.pdf
     March 01, 2012 - hospital stays increased by 50 percent or more from 1997 to 2010: skin and subcutaneous tissue infections … Septicemia (except in labor) 413 934 15.2 30.2 99% Skin and subcutaneous tissue infections … Respiratory failure; insufficiency; arrest (adult) 199 363 7.3 11.7 61% Intestinal infection … rate of hospitalization for asthma fell by 30 percent and doubled for skin and subcutaneous tissue infections … 68 percent, respectively; stays for mood disorders nearly doubled; and skin and subcutaneous tissue infections

277. Maskedstats Nis 2017 Core (pdf file)
     hcup-us.ahrq.gov/db/nation/nis/tools/stats/MaskedStats_NIS_2017_Core.PDF
     January 01, 2017 - JOINT/LIMB REATTACHMENT PROCEDURE OF UPPER EXTREMITIES 23,724 0.33% 485: KNEE PROCEDURES W PDX OF INFECTION … W MCC 366 0.01% 486: KNEE PROCEDURES W PDX OF INFECTION W CC 1,099 0.02% 487: KNEE PROCEDURES W PDX … OF INFECTION W/O CC/MCC 461 0.01% 488: KNEE PROCEDURES W/O PDX OF INFECTION W CC/MCC 1,925 0.03% 489 … : KNEE PROCEDURES W/O PDX OF INFECTION W/O CC/MCC 2,186 0.03% 492: LOWER EXTREM & HUMER PROC EXCEPT … PROC W CC 6,485 0.09% 858: POSTOPERATIVE OR POST-TRAUMATIC INFECTIONS W O.R.

278. Maskedstats Nis 2016 Core (pdf file)
     hcup-us.ahrq.gov/db/nation/nis/tools/stats/MaskedStats_NIS_2016_Core.PDF
     January 01, 2016 - Frequency Distribution for DRG_NOPOA DRG_NoPOA Frequency Percent of Total 485: KNEE PROCEDURES W PDX OF INFECTION … W MCC 384 0.01% 486: KNEE PROCEDURES W PDX OF INFECTION W CC 1,020 0.01% 487: KNEE PROCEDURES W PDX … OF INFECTION W/O CC/MCC 473 0.01% 488: KNEE PROCEDURES W/O PDX OF INFECTION W CC/MCC 1,892 0.03% 489 … : KNEE PROCEDURES W/O PDX OF INFECTION W/O CC/MCC 2,195 0.03% 492: LOWER EXTREM & HUMER PROC EXCEPT … PROC W CC 6,426 0.09% 858: POSTOPERATIVE OR POST-TRAUMATIC INFECTIONS W O.R.

279. Adverse Drug Events in U.S. Hospitals, 2010 Versus 2014 #234
     hcup-us.ahrq.gov/reports/statbriefs/sb234-Adverse-Drug-Events.jsp
     January 01, 2018 - Specific ADE causes included Antibiotics and anti-infectives Antibiotics, clostridium difficile infection

280. Clinical Conditions With Frequent, Costly Hospital Readmissions by Payer, 2020 (pdf file)
     hcup-us.ahrq.gov/reports/statbriefs/SB307-508.pdf
     November 03, 2021 - * The CCSR for septicemia includes all sepsis infection codes and does not include the criteria of … organ dysfunction. ** This includes complications, such as infection, for surgical or medical care other … Three genitourinary conditions at index admission—acute and unspecified renal failure, urinary tract infections … * The CCSR for septicemia includes all sepsis infection codes and does not include the criteria of … Notably, the CCSR category for septicemia includes all sepsis infection codes.