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141. Maskedstats Nis 2022 Core Weighted (pdf file)
     hcup-us.ahrq.gov/db/nation/nis/tools/stats/MaskedStats_NIS_2022_Core_Weighted.PDF
     January 01, 2022 - INFECTION OF NERVOUS SYSTEM EXCEPT VIRAL MENINGITIS WITH CC 7,120 0.02% 99: NON-BACTERIAL INFECTION … WITH MCC 3,995 0.01% 486: KNEE PROCEDURES WITH PRINCIPAL DIAGNOSIS OF INFECTION WITH CC 8,635 0.03% … 487: KNEE PROCEDURES WITH PRINCIPAL DIAGNOSIS OF INFECTION WITHOUT CC/MCC 3,355 0.01% 488: KNEE PROCEDURES … WITHOUT PRINCIPAL DIAGNOSIS OF INFECTION WITH CC/MCC 8,395 0.03% 489: KNEE PROCEDURES WITHOUT PRINCIPAL … DIAGNOSIS OF INFECTION WITHOUT CC/MCC 7,525 0.02% 492: LOWER EXTREMITY AND HUMERUS PROCEDURES EXCEPT

142. Nis 2004 Summarystats Severity (pdf file)
     hcup-us.ahrq.gov/db/nation/nis/tools/stats/NIS_2004_SummaryStats_SEVERITY.PDF
     January 01, 2004 - W/O CC 1155 0.01 441: ACUTE MAJOR EYE INFECTIONS W CC 361 0.00 442: ACUTE MAJOR EYE INFECTIONS W MCC … W/O CC 735 0.01 5011: KNEE PROC W PDX OF INFECTION W CC 819 0.01 5012: KNEE PROC W PDX OF INFECTION … INFECTION W CC 1122 0.01 5032: KNEE PROCS W/O PDX OF INFECTION W MCC 121 0.00 5040: EXT,FULL BURN W … Infection 127 0.00 INF06: Coccidioidomycosis 447 0.01 INF07: Coxsackie and ECHO Infections 284 0.00 … 10963 0.14 INF83: Other Fungal Infections 567 0.01 INF84: Other Infectious and Parasitic Infections

143. Section5 10 (pdf file)
     hcup-us.ahrq.gov/reports/factsandfigures/2007/pdfs/section5_10.pdf
     January 01, 2007 - 81 8.2 12.8 42 Infectious and parasitic 178 186‡ 100.0 100.0 5 Septicemia (blood infection … 60.7 43 Skin and subcutaneous tissue 124 202 100.0 100.0 63 Skin and subcutaneous tissue infections …  Anemia and skin and subcutaneous tissue infections each increased 76 percent.

144. Nis 2005 Summarystats Severity (pdf file)
     hcup-us.ahrq.gov/db/nation/nis/tools/stats/NIS_2005_SummaryStats_SEVERITY.PDF
     January 01, 2005 - WO CC 1279 0.02 441: ACUTE MAJOR EYE INFECTIONS W CC 458 0.01 442: ACUTE MAJOR EYE INFECTIONS W MCC … , FEMALE REPRO SYSTEM WO CC 3877 0.05 3681: INFECTIONS, FEMALE REPRO SYSTEM W CC 2018 0.03 3682: INFECTIONS … WO CC 763 0.01 5011: KNEE PROC W PDX OF INFECTION W CC 917 0.01 5012: KNEE PROC W PDX OF INFECTION … Infection 142 0.00 INF06: Coccidioidomycosis 522 0.01 INF07: Coxsackie and ECHO Infections 196 0.00 … 11502 0.14 INF83: Other Fungal Infections 650 0.01 INF84: Other Infectious and Parasitic Infections

145. Facts and Figures Exhibit 5.8
     hcup-us.ahrq.gov/reports/factsandfigures/2008/exhibit5_8.jsp
     January 01, 2008 - 133,300; spondylosis, intervertebral disc disorders, and other back problems: 121,800; urinary tract infections … Stays for urinary tract infections and fluid and electrolyte disorders also had frequent secondary MH … non-specific chest pain: 49,700; poisoning by psychotropic agents: 47,400; skin and subcutaneous tissue infections … Non-specific chest pain (49,700 stays), skin and subcutaneous tissue infections (45,700 stays), pneumonia

146. Appendix - Adverse Drug Events in U.S. Hospitals, 2010 Versus 2014 (pdf file)
     hcup-us.ahrq.gov/reports/statbriefs/sb234-appendix.pdf
     January 01, 2014 - E930.9 Unspecified antibiotic causing adverse effects in therapeutic use Clostridium difficile infection … 008.45 Intestinal infection due to Clostridium difficile Agency for Healthcare Research and

147. Origin of Adverse Drug Events in U.S. Hospitals, 2011 (pdf file)
     hcup-us.ahrq.gov/reports/statbriefs/sb158.pdf
     August 11, 2013 - ■ Overall, the most common specific ADEs were related to clostridium difficile infection (95 per … 4.0 14 Clostridium difficile infection … Clostridium difficile infection was the most common ADE cause, occurring at a rate of 95 per 10,000 … drugs Opiates/Narcotics NSAIDS Anticoagulants Steroids Antineoplastic drugs Clostridium difficile infection

148. Neds 2021 Ip Maskedstats (pdf file)
     hcup-us.ahrq.gov/db/nation/neds/stats/NEDS_2021_IP_MaskedStats.PDF
     January 01, 2021 - WITH MCC 532 0.01 486: KNEE PROCEDURES WITH PRINCIPAL DIAGNOSIS OF INFECTION WITH CC 1,117 0.02 487 … : KNEE PROCEDURES WITH PRINCIPAL DIAGNOSIS OF INFECTION WITHOUT CC/MCC 381 0.01 488: KNEE PROCEDURES … WITHOUT PRINCIPAL DIAGNOSIS OF INFECTION WITH CC/MCC 980 0.02 489: KNEE PROCEDURES WITHOUT PRINCIPAL … DIAGNOSIS OF INFECTION WITHOUT CC/MCC 508 0.01 please refer to the section on Description of Data … : KNEE PROCEDURES WITH PRINCIPAL DIAGNOSIS OF INFECTION WITHOUT CC/MCC 381 0.01 488: KNEE PROCEDURES

149. Section2 5 (pdf file)
     hcup-us.ahrq.gov/reports/factsandfigures/2008/pdfs/section2_5.pdf
     January 01, 2008 - 44 Non-specific chest pain 39 68 2.3 3.2 7.3 9.4 73 Skin and subcutaneous tissue infections … mood disorders (44 percent), non-specific chest pain (73 percent), and skin and subcutaneous tissue infections … ) of all discharges for alcohol-related conditions and about 10 percent of all discharges for skin infections

150. Ff 2009 Exhibit2 5 (pdf file)
     hcup-us.ahrq.gov/reports/factsandfigures/2009/pdfs/FF_2009_exhibit2_5.pdf
     January 01, 2009 - 3% 4% 64% Non-specific chest pain 39 78 2% 3% 99% Skin and subcutaneous tissue infections … (23 percent) of all stays for alcohol-related conditions and over 10 percent of all stays for skin infections … mood disorders (64 percent), non-specific chest pain (99 percent), and skin and subcutaneous tissue infections

151. Most Common Diagnoses and Procedures in U.S. Community Hospitals, 1996
     hcup-us.ahrq.gov/reports/natstats/commdx/table2c.htm
     February 11, 2011 - Urinary tract infections [159] 404,458 100.00 1.16 … Debridement of wound, infection or burn [169] 20,508 5.08 0.06 … Debridement of wound, infection or burn [169] 26,524 7.91 0.08 … Skin and subcutaneous tissue infections [197] 325,223 100.00 0.93 … Debridement of wound, infection or burn [169] 26,604 8.18 0.08

152. Maskedstats Nrd 2021 Core (pdf file)
     hcup-us.ahrq.gov/db/nation/nrd/stats/MaskedStats_NRD_2021_CORE.PDF
     January 01, 2021 - INFECTION OF NERVOUS SYSTEM EXCEPT VIRAL MENINGITIS WITH CC 3,481 0.02% 99: NON-BACTERIAL INFECTION … WITH MCC 1,835 0.01% 486: KNEE PROCEDURES WITH PRINCIPAL DIAGNOSIS OF INFECTION WITH CC 4,649 0.03% … 487: KNEE PROCEDURES WITH PRINCIPAL DIAGNOSIS OF INFECTION WITHOUT CC/MCC 1,633 0.01% 488: KNEE PROCEDURES … WITHOUT PRINCIPAL DIAGNOSIS OF INFECTION WITH CC/MCC 4,095 0.02% 489: KNEE PROCEDURES WITHOUT PRINCIPAL … DIAGNOSIS OF INFECTION WITHOUT CC/MCC 3,290 0.02% 492: LOWER EXTREMITY AND HUMERUS PROCEDURES EXCEPT

153. Statistical Brief #122: Septicemia in U.S. Hospitals, 2009 (pdf file)
     hcup-us.ahrq.gov/reports/statbriefs/sb122.pdf
     October 01, 2011 - percent) had a non-specific code that does not provide information on the organism re- sponsible for the infection … ; pneumonia; unspecified bacterial infections; chronic ulcer of skin; skin and subcutaneous tissue infections … bronchiectasis 162,500 194.3 Nutritional deficiencies 140,500 168.1 Delirium 140,500 168.0 Bacterial infection … myocarditis; cardiomyopathy 9,000 10.8 Infective arthritis and osteomyelitis 8,700 10.5 Intestinal infection … 8,300 10.0 Chronic obstructive pulmonary disease and bronchiectasis 8,200 9.9 HIV infection 7,900

154. Exhibit 2.3 Most Frequent Diagnoses by Sex
     hcup-us.ahrq.gov/reports/factsandfigures/figures/2005/2005_2_3.jsp
     January 01, 2005 - graft 316.1 11.975 2.0 8 298.2 10.292 1.3 15 197 Skin and subcutaneous tissue infections … degenerative joint disease) 279.9 11.860 1.7 12 455.3 17.915 2.0 6 159 Urinary tract infections

155. HCUP Statistical Brief #36: Trends in Potentially Preventable Hospitalizations among Adults and Children, 1997-2004 (pdf file)
     hcup-us.ahrq.gov/reports/statbriefs/sb36.pdf
     August 01, 2007 - In contrast, the rate of hospitalization for urinary tract infections rose from 159.0 admissions per … Bacterial pneumonia 399.2 444.6 408.9 NS Dehydration 136.9 140.5 124.6 ↓ (9.0%) Urinary tract infection … 24.8%) Pediatric gastroenteritis (age 4 months to 17 years) 201.1 172.8 178.7 NS Urinary tract infection … pneumonia $5,089 $6,630 $7,050 ↑ (38.5%) Dehydration $1,120 $1,380 $1,436 ↑ (28.2%) Urinary tract infection … Pediatric gastroenteritis (age 4 months to 17 years) $219 $217 $241 ↑ (10.0%) Urinary tract infection

156. Readmissions to U.S. Hospitals by Procedure, 2010 (pdf file)
     hcup-us.ahrq.gov/reports/statbriefs/sb154.pdf
     March 01, 2013 - readmission rates were for amputation of a lower extremity (22.8 percent); debridement of a wound, infection … of cardiac pacemaker or cardioverter/defibrillator 149,147 23,057 15.5 19 Debridement of wound, infection … All-cause 30-day readmission rates for debridement of a wound, infection, or burn by age and insurance … 167 Mastectomy (operation to remove the whole breast) 61,885 3,868 6.3 169 Debridement of wound, infection … or burn (surgical removal of foreign material and dead tissue from a wound, infection or burn) 148,544

157. Statistical Brief #154
     hcup-us.ahrq.gov/reports/statbriefs/sb154.jsp
     April 01, 2013 - readmission rates were for amputation of a lower extremity (22.8 percent); debridement of a wound, infection … pacemaker or cardioverter/defibrillator 149,147 23,057 15.5 19 Debridement of wound, infection … Readmission rates for debridement of a wound, infection, or burn are shown in figure 2. … All-cause 30-day readmission rates for debridement of a wound, infection, or burn by age and insurance … or burn (surgical removal of foreign material and dead tissue from a wound, infection or burn) 148,544

158. Statistical Brief #122
     hcup-us.ahrq.gov/reports/statbriefs/sb122.jsp
     October 01, 2011 - percent) had a non-specific code that does not provide information on the organism responsible for the infection … ; pneumonia; unspecified bacterial infections; chronic ulcer of skin; skin and subcutaneous tissue infections … Nutritional deficiencies 140,500 168.1 Delirium 140,500 168.0 Bacterial infection … cardiomyopathy 9,000 10.8 Infective arthritis and osteomyelitis 8,700 10.5 Intestinal infection … 8,300 10.0 Chronic obstructive pulmonary disease and bronchiectasis 8,200 9.9 HIV infection

159. Neds 2014 Maskedstats Ip (pdf file)
     hcup-us.ahrq.gov/db/nation/neds/stats/NEDS_2014_MaskedStats_IP.PDF
     January 01, 2014 - W MCC 394 0.01 486: KNEE PROCEDURES W PDX OF INFECTION W CC 821 0.02 487: KNEE PROCEDURES W PDX OF … INFECTION W/O CC/MCC 404 0.01 488: KNEE PROCEDURES W/O PDX OF INFECTION W CC/MCC 720 0.02 489: KNEE … PROCEDURES W/O PDX OF INFECTION W/O CC/MCC 602 0.01 490: BACK & NECK PROC EXC SPINAL FUSION W CC/MCC … W MCC 396 0.01 486: KNEE PROCEDURES W PDX OF INFECTION W CC 820 0.02 487: KNEE PROCEDURES W PDX OF … INFECTION W/O CC/MCC 404 0.01 488: KNEE PROCEDURES W/O PDX OF INFECTION W CC/MCC 728 0.02 489: KNEE

160. Neds 2013 Maskedstats Ip (pdf file)
     hcup-us.ahrq.gov/db/nation/neds/stats/NEDS_2013_MaskedStats_IP.PDF
     January 01, 2013 - W MCC 369 0.01 486: KNEE PROCEDURES W PDX OF INFECTION W CC 765 0.02 487: KNEE PROCEDURES W PDX OF … INFECTION W/O CC/MCC 378 0.01 488: KNEE PROCEDURES W/O PDX OF INFECTION W CC/MCC 734 0.02 489: KNEE … PROCEDURES W/O PDX OF INFECTION W/O CC/MCC 617 0.01 490: BACK & NECK PROC EXC SPINAL FUSION W CC/MCC … W MCC 371 0.01 486: KNEE PROCEDURES W PDX OF INFECTION W CC 767 0.02 487: KNEE PROCEDURES W PDX OF … INFECTION W/O CC/MCC 378 0.01 488: KNEE PROCEDURES W/O PDX OF INFECTION W CC/MCC 740 0.02 489: KNEE