-
effectivehealthcare.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1506.pdf
June 01, 2015 - exploring ketamine’s optimal delivery
route and administration protocols for treating depression indications … Scopolamine is a muscarinic antagonist approved for treating several
indications including motion sickness … absence of formal
development programs, ketamine and scopolamine use is off-label for depression indications … experts, with clinical and research
backgrounds, commented on off-label scopolamine for the same indications … patients possibly preferring ketamine and scopolamine to treatments such as TMS and ECT for
these indications
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0274_03-10-2008.pdf
January 01, 2008 - This topic is best suited for a clinical effectiveness review
that evaluates expanded indications and
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-drugs-utilization_research.pdf
January 01, 2011 - Ophthalmology Preferred
Practice Pattern Guidelines.6 In alignment with bevacizumab’s labeled
cancer indications … lymphatic and hematopoietic
tissue (200.x to 208.x), likely driven by the
biologic’s use for these indications … These data are consistent with the biologic’s indications for advanced renal
cell carcinoma and hepatocellular … These
results are consistent with peginterferon’s labeled indications for hepa-
titides. … Systematic review: reliability of
compendia methods for off-label oncology indications.
-
effectivehealthcare.ahrq.gov/products/recombinant-factor-viia/research
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/atypical-antipsychotics-off-label-update_executive.pdf
September 01, 2011 - These drugs
have been used off-label (i.e., for
indications not approved by FDA) for the
treatment of … New or increased adverse effects of off-label
indications have been observed and new atypicals
(asenapine … show regarding
the efficacy and comparative effectiveness of atypical
antipsychotics for off-label indications … Key Question 5: What is the effective dose and time
limit for off-label indications? … The dosages used in off-label indications
varied from those used in on-label indications.
-
effectivehealthcare.ahrq.gov/sites/default/files/ch_5-user-guide-to-ocer_130129.pdf
January 01, 2012 - Active comparators are users of treatments
that are not associated with indications for the
exposure … involves requirement for the presence
of certain diagnoses, the absence of diagnoses
for alternative indications … For nonuser
comparisons, restriction of nonusers to those with
similar indications is advisable. … Indications
for propensity scores and review of their use in
pharmacoepidemiology. … Indications,
outcomes, and provider volumes for
carotid endarterectomy. JAMA.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/atypical-antipsychotics-off-label_executive.pdf
January 01, 2007 - What does the evidence
show regarding the effectiveness of
atypical antipsychotics for off-label
indications … How do
atypical antipsychotic medications
compare with other drugs for treating off-
label indications … What are the appropriate
dose and time limit for off-label
indications? … reach conclusions about the efficacy of
atypical antipsychotic medications for any of the off-
label indications … More head-to-head trials comparing atypical
antipsychotics are needed for off-label indications other
-
effectivehealthcare.ahrq.gov/sites/default/files/comparator-selection-in-observational-chapter-5.pptx
January 01, 2013 - Indications for propensity scores and review of their use in pharmacoepidemiology. … Indications for propensity scores and review of their use in pharmacoepidemiology. … Active comparators are users of treatments that are not associated with indications for the exposure … However, because many treatments are approved for and/or clinically used to treat multiple indications … treatment is more problematic in comparisons across different treatment modalities, especially when indications
-
effectivehealthcare.ahrq.gov/products/type-2-diabetes-insulin/research
-
effectivehealthcare.ahrq.gov/sites/default/files/dementia-horizon-scan-high-impact-1506.pdf
June 01, 2015 - preliminary phase III data for drugs (or
preliminary late-phase clinical trial data for off-label drug indications … This drug, in
various formulations, is approved and widely used to manage diabetes indications; no major … manufacturers are testing it for other indications, so its potential use for treating AD would
be
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-cough_research-protocol.pdf
October 22, 2012 - Trademark Name
Generic Name Manufacturer
Dosage Frequency Methods of
Administration
FDA
Status
Indications … Trademark Name
Generic Name Manufacturer
Dosage Frequency Methods of
Administration
FDA
Status
Indications … Trademark Name
Generic Name Manufacturer
Dosage Frequency Methods of
Administration
FDA
Status
Indications … Trademark Name
Generic Name Manufacturer
Dosage Frequency Methods of
Administration
FDA
Status
Indications … Trademark Name
Generic Name Manufacturer
Dosage Frequency Methods of
Administration
FDA
Status
Indications
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/stem-cell-children_research-protocol.pdf
November 01, 2010 - Pediatric HSCT Indications to Be Addressed with Narrative Review
Malignant
Hematopoietic Setting … Pediatric HSCT Indications to Be Addressed with Narrative Review (continued)
Nonmalignant Setting … Pediatric HSCT Indications to Be Addressed with Systematic Review
Malignant
Hematopoietic Setting … Pediatric HSCT Indications to Be Addressed with Systematic Review
Nonmalignant Setting(s) Type Of … Appendix
Search strategy for indications and settings in the systematic review.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/tonsillectomy_executive.pdf
January 01, 2017 - .1
Indications for Tonsillectomy
Tonsillectomy has two primary indications:
recurrent tonsillitis … Few studies evaluating perioperative agents
reported any revisits for non-PTH indications. … We also included only studies addressing
tonsillectomy for the two most common indications for
the … Trends in the indications for pediatric
tonsillectomy or adenotonsillectomy. … Indications for
tonsillectomy: a 10 year retrospective review.
-
effectivehealthcare.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1412.pdf
December 01, 2014 - for an intranasal form of purified S-ketamine, also known as esketamine, for
treating depression indications … because this administration
route is more established than other administration routes for these indications … would be high; additionally, they stated that ketamine would be preferred to TMS and ECT for
these indications … .62,65
Health care delivery infrastructure and patient management: For these indications,
ketamine … In the absence of formal development programs, scopolamine use is off
label for depression indications
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/tonsillectomy_research-protocol.pdf
February 10, 2016 - with similar populations.4 Variation in rates continues despite improved evidence about
indications … Indications for tonsillectomy for recurrent infection have been defined as “severe tonsillitis … heterogeneity of approaches to tonsillectomy and
covariates associated with underlying indications … Trends in the indications for pediatric tonsillectomy or
adenotonsillectomy. … Indications for tonsillectomy: a 10 year
retrospective review.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetes-glucose-control_research.pdf
July 01, 2010 - We evaluated whether early use of
this drug was consistent with the FDA-approved indications for use … investigated whether use of this drug soon after its approval was consistent with the FDA-
approved indications … An important observation is that this new drug was used for off-label indications very
early after approval … as monotherapy, and was used an adjunct to thiazolidinediones and to insulin, also not
FDA-approved indications … testing its use with thiazolidinediones and testing its
use as a monotherapy, which may alter its indications
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-biopsy-update_clinician.pdf
May 01, 2016 - in the studies was similar to that of
women undergoing breast biopsy in the United States, and
the indications … were similar to the prevalent indications in
clinical practice (i.e., mammographic findings of suspicious
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cesarean-birth_research.pdf
January 01, 2020 - • Operational definitions of indications for cesarean are incompatible, or poorly described,
across … Consider the relationship between refined definitions of indications for cesarean and existing population … Develop definitions of indications
for cesarean that can be validated
from medical records and case … Middle
Intervention
(operationalize definitions
of indications to make them
discrete, nonoverlapping … Middle
Develop definitions of indications for cesarean that can be validated from medical
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/epc-making-sure-evidence-understood.pdf
July 01, 2020 - PUse questions that ask about indications for multiple procedures
Inappropriate What are the appropriate … indications for arthroscopic surgery?
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/safety-vaccines-protocol.pdf
January 30, 2020 - Research and Quality (AHRQ) review of vaccine
safety,2 a number of new vaccines have been approved, and indications … For example, the 9-valent HPV vaccine (HPV-9) has replaced the 2- and 4-
valent HPV vaccines, with indications … Searches will be restricted by publication year only for vaccines and vaccine
indications that have … HPV9)
Children, adults New vaccine since last review
(Gardasil 9 approved 2014; since then
age indications … adults None
Influenza, inactivated (IIV) Children, adults,
pregnant women
New formulations; age indications