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Showing results for "indications".
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21. Hematopoietic Stem-Cell Transplantation in the Pediatric Population | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/stem-cell-children/research
    December 01, 2019 - The strength of evidence for specific indications was graded as high for 2 indications, moderate or low … harm of HSCT versus standard therapies or disease natural history was insufficient for most pediatric indications

22. Utilization and Clinical Data on In-Hospital Off-Label Uses of Recombinant Factor VIIa | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/recombinant-factor-viia/clinician
    March 01, 2020 - regarding the serious thrombotic events associated with the use of rFVIIa (NovoSeven® RT) outside labeled indications … typically only given in the form of 1-2 infusions, rather than multiple infusions seen in some of the other indications … is based on Comparative Effectiveness of In-Hospital Use of Recombinant Factor VIIa for Off-Label Indications … Project Timeline Comparative Effectiveness of In-Hospital Use of Recombinant Factor VIIa for Off-Label Indications

23. Effective Health Care (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND_0004_03-11-2008.pdf
    January 01, 2008 - topic will move forward for refinement as a systematic review with a focus on COPD and ACPE as primary indications … Topic refinement may consider an expansion of the scope to include other indications for which there

24. White Paper: Enhancing Systematic Review Methods by Incorporating Unpublished Drug Trials (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/unpublished-drug-trials-white-paper.pdf
    December 01, 2024 - FDA-Approved Indications Versus Off-Label Uses: FDA reviews only cover drug- indication combinations … First Approved Versus Subsequently Approved Indications: Access to FDA reviews can vary. … Reviews are more reliably posted for first-approved indications (e.g., ziprasidone for schizophrenia … ) compared to subsequent indications (e.g., ziprasidone for acute bipolar mania).9 To check for the … indications.

25. Recombinant-Factor-Viia Clinician (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/recombinant-factor-viia_clinician.pdf
    October 01, 2010 - regarding the serious thrombotic events associated with the use of rFVIIa (NovoSeven® RT) outside labeled indications … is based on Comparative Effectiveness of In-Hospital Use of Recombinant Factor VIIa for Off-Label Indications … only given in the form of 1-2 infusions, rather than multiple infusions seen in some of the other indications

26. Ced -Appendix-2 (xls file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/ced%20-appendix-2.xlsx
    October 12, 2022 - , without FDA-approval for marketing for these indications. … Deeply concerned about CMS’ employment of CED for FDA-approved drugs – whether for on-label indications … or other medically accepted indications. … , without FDA-approval for marketing for these indications. … or other medically accepted indications Patient access barriers under CED (equity) No clear pathway

27. Evidence-based Practice Center Systematic Review Protocol (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/atypical-antipsychotics-off-label-update_disposition-comments.pdf
    September 01, 2011 - Now, many have received FDA approval for indications to treatment these disorders. … And, as our report indicates, in this update there are more "new" off-label indications than there … are previous off-label indications that now have FDA approval. … In view of these approvals, these agents and indications might be left out of the current report on … I realize this will not be applicable to most of the off-label indications, but this would apply to

28. Introduction to N-of-1 Trials: Indications and Barriers (Chapter 1) | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/n-1-trials/research-2014-4
    August 01, 2019 - Home Evidence Reports Introduction to N-of-1 Trials: Indications … In this chapter, we introduce n-of-1 trials by providing definitions and a rationale, delineating indications … Indications, Contraindications, and Limitations N-of-1 trials are indicated whenever there is substantial … Subgroup analysis in randomised controlled trials: importance, indications, and interpretation. … Introduction to N-of-1 Trials: Indications and Barriers.

29. Future Research Needs for Hematopoietic Stem-Cell Transplantation in the Pediatric Population | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/stem-cell-children-future/research
    December 01, 2019 - Excerpt For many pediatric indications, the use of hematopoietic stem-cell transplantation (HSCT) is … In the absence of these data, the comparative effectiveness and harms of HSCT for these indications is

30. Progestogens-Preterm-Birth Executive (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/progestogens-preterm-birth_executive.pdf
    September 01, 2012 - We constructed models to address two aspects of clinical utility—grouping the RCTs: (1) by the indications … Indications for treatment varied, including a history of preterm birth in 10 investigations, preterm … The heterogeneity of the studies that included women with varied indications for progestogen treatment … Categorization of indications in the largest database study found 79.5 percent had a prior preterm … Across indications, data are sparse to evaluate influence on near-term and long-term maternal and infant

31. Evidence-based Practice Center Systematic Review Protocol (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/recombinant-factor-viia_disposition-comments.pdf
    June 01, 2010 - Review Title: Comparative Effectiveness of In-Hospital Use of Recombinant Factor VIIa for Off-Label Indications … Comparative Effectiveness of Recombinant Factor VIIa for Off-Label Indications vs. Usual Care. … The Draft Report erroneously concludes that the use of rFVIIa outside of approved indications is now … The Draft Report erroneously concludes that the use of rFVIIa outside of approved indications is now … A similar analysis can be done for other indications.

32. In patients with cerebral palsy (CP) and difficulties with feeding, what is the effectiveness of of anti-reflux procedure (since often done in conjunction with gastrostomy placement) or type of tube (J-tube or G-J tube versus typical PEG… | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/in-patients-with-cerebral-palsy-cp-and-difficulties-with-feeding-what-is-the-effectiveness-of-of-anti-reflux-procedure-since-often-done-in-conjunction-with-gastrostomy-placement-or-type-of-tube-j-tube-or-g-j-tube-versus-typi
    November 01, 2017 - (Please include specific details such as age range, gender, coexisting diagnoses, and indications for … systematic review focusing on feeding interventions may provide clinicians and researchers with clear indications … For example, there is variation in indications and timing for feeding gastrostomy and whether or not

33. #05 DEPRESSION (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1506.pdf
    June 01, 2015 - exploring ketamine’s optimal delivery route and administration protocols for treating depression indications … Scopolamine is a muscarinic antagonist approved for treating several indications including motion sickness … absence of formal development programs, ketamine and scopolamine use is off-label for depression indications … experts, with clinical and research backgrounds, commented on off-label scopolamine for the same indications … patients possibly preferring ketamine and scopolamine to treatments such as TMS and ECT for these indications

34. Diagnosis and Management of Infantile Hemangioma | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/infantile-hemangioma/research
    December 01, 2019 - Literature addressing contextual questions suggested that referral indications include large size; segmental … Conclusions Our review for contextual questions described a range of indications for referral and suggested

35. Progestogens for Prevention of Preterm Birth | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/progestogens-preterm-birth/research
    December 01, 2019 - The strength of the evidence supporting its use for these indications is moderate and low, respectively … Across indications, data are sparse to evaluate influence on near-term outcomes such as neonatal mortality

36. Effective Health Care (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND_0274_03-10-2008.pdf
    January 01, 2008 - This topic is best suited for a clinical effectiveness review that evaluates expanded indications and

37. Cancer-Drugs-Utilization Research (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/cancer-drugs-utilization_research.pdf
    January 01, 2011 - Ophthalmology Preferred Practice Pattern Guidelines.6 In alignment with bevacizumab’s labeled cancer indications … lymphatic and hematopoietic tissue (200.x to 208.x), likely driven by the biologic’s use for these indications … These data are consistent with the biologic’s indications for advanced renal cell carcinoma and hepatocellular … These results are consistent with peginterferon’s labeled indications for hepa- titides. … Systematic review: reliability of compendia methods for off-label oncology indications.

38. Key Questions 1. Does routine preoperative testing compared to no testing or alternative testing strategies improve outcomes (such as surgical complications, other morbidity, and mortality) among patients undergoing elective surgery? 2.… | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/key-questions-1-does-routine-preoperative-testing-compared-to-no-testing-or-alternative-testing-strategies-improve-outcomes-such-as-surgical-complications-other-morbidity-and-mortality-among-patients-undergoing-elective-surg
    November 01, 2017 - (Please include specific details such as age range, gender, coexisting diagnoses, and indications for … practice advisory3 noting that "preoperative tests should not be ordered routinely," and it outlines indications … practice advisory3 noting that "preoperative tests should not be ordered routinely," and it outlines indications

39. Layout 1 (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/atypical-antipsychotics-off-label-update_executive.pdf
    September 01, 2011 - These drugs have been used off-label (i.e., for indications not approved by FDA) for the treatment of … New or increased adverse effects of off-label indications have been observed and new atypicals (asenapine … show regarding the efficacy and comparative effectiveness of atypical antipsychotics for off-label indications … Key Question 5: What is the effective dose and time limit for off-label indications? … The dosages used in off-label indications varied from those used in on-label indications.

40. Telehealth for Acute and Chronic Care Consultations | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/telehealth-acute-chronic/research
    August 01, 2019 - producing generally either better outcomes or no difference from comparators in settings and clinical indications … there was no difference between telehealth and the comparators across the settings and for the clinical indications