-
effectivehealthcare.ahrq.gov/products/observational-research-scores/research
May 15, 2012 - Confounding by Indication
Confounding by indication is a specific type of confounding that is commonly … In some cases confounding by indication can be intractable. … universally followed by prescribers, then there would be no exposure variation among those with the indication … Another problem with addressing confounding by indication arises when the indications are not adequately … Since LDL level is a primary indication for statin therapy and higher LDL levels are anticipated to influence
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/antibiotics-respiratory-infection_research-protocol.pdf
September 22, 2014 - Key Question 2: For patients with an acute respiratory tract infection (RTI) and no clear
indication … Key Question 3: For patients with an acute respiratory tract infection (RTI) and no clear
indication … Key Question 4: For patients with an acute respiratory tract infection (RTI) and no clear
indication … sinusitis; cough and
common cold.4
2) Parents of pediatric patients with acute RTI and no clear indication … indication!
for!antibiotics!
2)!Adults!and/or!
children!without!
acute!RTI!
3)!Clinicians!in!
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/stem-cell-children_research-protocol.pdf
November 01, 2010 - The role of HSCT in pediatric diseases
depends in part on the indication for which it is being used. … PICOTS
Indication 1. … of HSCT; quality of life (QOL)
T: All durations of follow-up will be included
S: Inpatient
Indication … Level of Evidence for the Narrative Reviews by Indication
Disease Type Supporting Literature
Malignant … Is the treatment setting for the particular disease indication included in the
systematic review?
-
effectivehealthcare.ahrq.gov/products/transparency-neuropathy/research-protocol
September 06, 2016 - Finally, the full team will consider if the final conclusions are influenced by any indication of reporting … Finally, the full team will consider if the final conclusions are influenced by any indication of reporting
-
effectivehealthcare.ahrq.gov/products/congestive-heart-failure-medicines/research
March 31, 2010 - These conclusions are tempered by concerns that substantial residual "confounding by indication" might … The inability to fully adjust for this confounding by indication would result in falsely elevated hazard … stratified the underlying hazard by the propensity score for receipt of H-ISDN to reduce confounding by indication … incorporation of the propensity score into our analyses had little or no effect on the confounding by indication
-
effectivehealthcare.ahrq.gov/products/angina-heart-attack-treatments/research
November 04, 2013 - without oral anticoagulation in the postdischarge management of acute coronary syndrome patients with an indication
-
effectivehealthcare.ahrq.gov/products/prostate-cancer-radiation/research
November 30, 2012 - national trends can be studied using Medicare claims alone with minimal worry about confounding due to indication
-
effectivehealthcare.ahrq.gov/get-involved/nominated-topics/for-persons-who-present-with-acute-cough-illness-aci-what-is-the-comparative-effectiveness-of-various-interventions-for-reducing-inappropriate-antimicrobial-use
April 12, 2012 - All persons presenting with ACI in the outpatient or emergency setting who do not have a clear indication
-
effectivehealthcare.ahrq.gov/sites/default/files/ch-7-user-guide-to-ocer_130129.pdf
March 29, 2012 - Provider Actions
Confounding by indication: Confounding by
indication, also referred to as “channeling … the outcome being investigated
need to be adequately measured and modeled to
address confounding by indication … Indication for treatment was found to
be a strong instrument45 and provider and ecologic
causes of … Confounding by
indication and channeling over time: the
risks of beta 2-agonists. … Confounding by indication: the case
of calcium channel blockers.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antibiotics-respiratory-infection_disposition-comments.pdf
January 27, 2016 - The population of
interest is defined as “…patients with an
acute RTI and no clear indication for … “Clear
indication’ is a matter of interpretation and
influenced by condition, indication, setting … At what ‘number needed to treat’ to
reduce a particular outcome does the
indication for antibiotics … in the
inclusion of participants in studies who did
have a clear indication and the exclusion of … studies which included a lot of participants
without a clear indication for antibiotics.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/tonsillectomy_executive.pdf
January 01, 2017 - than 15
percent of all surgical procedures in children
under the age of 15 years.1, 2 The primary
indication … Currently, the most common indication for tonsillectomy
is OSDB (i.e., breathing difficulties during … We
did not assess harms separately by indication because there
is no reason to expect that they would … as surgical indication varied across studies. … These effects may be due to
confounding by indication as indication varied across
studies.
-
effectivehealthcare.ahrq.gov/get-involved/nominated-topics/updating-treatments-fecal-incontinence-iii
March 15, 2021 - separate and distinct from other bulking agents, as none of the other agents are approved by FDA for this indication
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/radiotherapy-proton-beam_research.pdf
May 01, 2012 - We separately analyzed the
number and proportion of denied claims by year, provider, and indication … Reimbursement
per patient varies by treatment
indication. … 37.3
Table 3: Characteristics of proton beam radiotherapy users in Medicare, by demography and
indication
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/congestive-heart-failure-medicines_research.pdf
March 01, 2010 - These conclusions are tempered by concerns that substantial
residual “confounding by indication” might … The inability to fully adjust for this
confounding by indication would result in falsely elevated hazard … stratified the underlying hazard by the propensity score for receipt of H-ISDN to
reduce confounding by indication … incorporation of the propensity score into our analyses had
little or no effect on the confounding by indication
-
effectivehealthcare.ahrq.gov/sites/default/files/dementia-horizon-scan-high-impact-1406.pdf
February 01, 2015 - patient advocacy groups that are investigating various delivery methods and
forms of insulin for this indication … populations and may clarify optimal
dosages, administration frequency, and insulin formulations for this indication … As a result, using intranasal insulin to treat AD is an off-
label indication. … Intranasal insulin for treating AD is not sold in prefabricated intranasal
delivery packages for this indication
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/labor-dystocia_research-protocol.pdf
July 28, 2016 - These
increased risks are the underlying indication for cesarean delivery in the setting of labor
dystocia … For the purposes of this review, women who are
undergoing induction of labor for any indication are … For the purposes
of this review, women who are undergoing induction of
labor for any indication are … <15 or >44
years of age
• Women in preterm labor
• Women undergoing
labor induction for any
indication … • KQs 1, 3-9:
o Maternal
For admission to NICU,
studies which do not report
length of stay if indication
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-disease-medicine_surveillance.pdf
October 01, 2012 - benefits
appeared to be limited to
specific CKD subgroups, some
of which already had a clinical
indication … Patients with
hyperlipidemia and no coronary
artery disease may not
otherwise have an indication for … Patients with systolic CHF
already have an indication for
beta blockers, regardless of
whether they … Patients with hyperlipidemia and
no coronary artery disease may not
otherwise have an indication for … Patients with systolic CHF already have an
indication for beta blockers, regardless of
whether they
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-anemia-update_disposition-comments.pdf
April 25, 2013 - of the evidence from very diverse trials, many of which
investigated ESA use outside of the typical indication … Although not an FDA-approved indication for ESA
use those results were included in the synthesis
here … used to derive estimates for mortality
and other outcomes were done before FDA limited the labeled indication … with the worse prognosis have the greatest harms, which is in
some ways consistent with the renal indication … Although not an FDA-approved
indication for ESA use, those results were
included because the population
-
effectivehealthcare.ahrq.gov/sites/default/files/developmental-delays-horizon-scan-high-impact-1406.pdf
June 01, 2014 - patients with ASD, and one
company is researching a proprietary intranasal delivery system for a similar indication … care for treating social dysfunction in ASDs, because of the
absence of other medications for this indication … systems expert commenting on this intervention noted that adoption of intranasal
oxytocin for this indication … and use this
intervention, overall, experts concluded that intranasal oxytocin, if adopted for this indication
-
effectivehealthcare.ahrq.gov/products/diabetes-glucose-control/research
August 04, 2010 - frequently early after its approval as monotherapy or with a thiazolidinedione; neither is an FDA approved indication … The indication for which exenatide was approved is "to improve glycemic control in patients with type … very early after approval; it was used as a monotherapy in 14% of the patients despite not having an indication