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Showing results for "indication".
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41. Ch-7-User-Guide-To-Ocer 130129 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/ch-7-user-guide-to-ocer_130129.pdf
    March 29, 2012 - Provider Actions Confounding by indication: Confounding by indication, also referred to as “channeling … the outcome being investigated need to be adequately measured and modeled to address confounding by indication … Indication for treatment was found to be a strong instrument45 and provider and ecologic causes of … Confounding by indication and channeling over time: the risks of beta 2-agonists. … Confounding by indication: the case of calcium channel blockers.

42. Disposition of Comments for CER 163 Appropriate Antibiotics (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/antibiotics-respiratory-infection_disposition-comments.pdf
    January 27, 2016 - The population of interest is defined as “…patients with an acute RTI and no clear indication for … “Clear indication’ is a matter of interpretation and influenced by condition, indication, setting … At what ‘number needed to treat’ to reduce a particular outcome does the indication for antibiotics … in the inclusion of participants in studies who did have a clear indication and the exclusion of … studies which included a lot of participants without a clear indication for antibiotics.

43. Tonsillectomy for Obstructive Sleep-Disordered Breathing or Recurrent Throat Infection in Children (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/tonsillectomy_executive.pdf
    January 01, 2017 - than 15 percent of all surgical procedures in children under the age of 15 years.1, 2 The primary indication … Currently, the most common indication for tonsillectomy is OSDB (i.e., breathing difficulties during … We did not assess harms separately by indication because there is no reason to expect that they would … as surgical indication varied across studies. … These effects may be due to confounding by indication as indication varied across studies.

44. MEDICAL MANAGEMENT OF CONGESTIVE HEART FAILURE AND THE EFFECTIVENESS OF ISOSORBIDE DINITRATE AND HYDRALAZINE (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/congestive-heart-failure-medicines_research.pdf
    March 01, 2010 - These conclusions are tempered by concerns that substantial residual “confounding by indication” might … The inability to fully adjust for this confounding by indication would result in falsely elevated hazard … stratified the underlying hazard by the propensity score for receipt of H-ISDN to reduce confounding by indication … incorporation of the propensity score into our analyses had little or no effect on the confounding by indication

45. DEMENTIA INCLUDING ALZHEIMER'S #04 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/dementia-horizon-scan-high-impact-1406.pdf
    February 01, 2015 - patient advocacy groups that are investigating various delivery methods and forms of insulin for this indication … populations and may clarify optimal dosages, administration frequency, and insulin formulations for this indication … As a result, using intranasal insulin to treat AD is an off- label indication. … Intranasal insulin for treating AD is not sold in prefabricated intranasal delivery packages for this indication

46. Radiotherapy-Proton-Beam Research (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/radiotherapy-proton-beam_research.pdf
    May 01, 2012 - We separately analyzed the number and proportion of denied claims by year, provider, and indication … Reimbursement per patient varies by treatment indication. … 37.3 Table 3: Characteristics of proton beam radiotherapy users in Medicare, by demography and indication

47. labor-dystocia-protocol-amended-160728 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/labor-dystocia_research-protocol.pdf
    July 28, 2016 - These increased risks are the underlying indication for cesarean delivery in the setting of labor dystocia … For the purposes of this review, women who are undergoing induction of labor for any indication are … For the purposes of this review, women who are undergoing induction of labor for any indication are … <15 or >44 years of age • Women in preterm labor • Women undergoing labor induction for any indication … • KQs 1, 3-9: o Maternal For admission to NICU, studies which do not report length of stay if indication

48. Kidney-Disease-Medicine Surveillance (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-disease-medicine_surveillance.pdf
    October 01, 2012 - benefits appeared to be limited to specific CKD subgroups, some of which already had a clinical indication … Patients with hyperlipidemia and no coronary artery disease may not otherwise have an indication for … Patients with systolic CHF already have an indication for beta blockers, regardless of whether they … Patients with hyperlipidemia and no coronary artery disease may not otherwise have an indication for … Patients with systolic CHF already have an indication for beta blockers, regardless of whether they

49. Disposition of Comments for Epoetin and Darbepoetin for Managing Anemia in Patients Undergoing Cancer Treatment (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-anemia-update_disposition-comments.pdf
    April 25, 2013 - of the evidence from very diverse trials, many of which investigated ESA use outside of the typical indication … Although not an FDA-approved indication for ESA use those results were included in the synthesis here … used to derive estimates for mortality and other outcomes were done before FDA limited the labeled indication … with the worse prognosis have the greatest harms, which is in some ways consistent with the renal indication … Although not an FDA-approved indication for ESA use, those results were included because the population

50. #06 Developmental Delays ADHD, and Autism (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/developmental-delays-horizon-scan-high-impact-1406.pdf
    June 01, 2014 - patients with ASD, and one company is researching a proprietary intranasal delivery system for a similar indication … care for treating social dysfunction in ASDs, because of the absence of other medications for this indication … systems expert commenting on this intervention noted that adoption of intranasal oxytocin for this indication … and use this intervention, overall, experts concluded that intranasal oxytocin, if adopted for this indication

51. Disposition of Comments for Venous Thromboembolism Prophylaxis in Orthopedic Surgery (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/blood-clots-hip-knee-surgery_disposition-comments.pdf
    March 01, 2012 - This is because such studies do not provide any indication of either the direction or magnitude of … The indication does not have to be for that which is under investigation. … Apixaban has yet to be FDA approved for an indication and therefore is excluded from this CER. … All agents evaluated in the CER must have a current FDA approved indication for use. … In a general CER includes only products with a current FDA approval for an indication.

52. #05 DEPRESSION (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1306.pdf
    October 01, 2014 - obsessive-compulsive disorder, which marked the first FDA approval of any DBS device for a psychiatric indication … FDA has granted the agent fast track status for this indication.1 Korlym was FDA approved in 2012 for … If approved for this indication, DBS is expected to be positioned as an additional second-line option … sometimes abused as a street drug (“Special K”), which may affect the regulatory pathway for this indication … HDE approval to commercialize the first deep brain stimulation (DBS) therapy for a psychiatric indication

53. DEcIDE 32: The Incident User Design in Comparative Effectiveness Research (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/incident-user-design_research.pdf
    May 01, 2012 - controlled trial protocols.23 The extent of any difference in the absolute risk probably depends on the indication … treatment more accurately and put investigators in a better position to control possible confounding by indication … started an entirely unrelated class of medications—instead of an alternative treatment for the same indication … Using comparator interventions with the same indication can reduce confounding substantially.37 Similarly … Non-users are different from patients using placebo as they may not have the indication for use or may

54. #05 DEPRESSION (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/05_depression_potential_high_impact_2012-12-10.pdf
    January 01, 2012 - obsessive-compulsive disorder, which marked the first FDA approval of any DBS device for a psychiatric indication … FDA has granted the agent fast track status for this indication. 2 Clinical Pathway at Point of … If approved for this indication, DBS is expected to be positioned as an additional second-line therapeutic … sometimes abused as a street drug (“Special K”), which may affect the regulatory pathway for this indication … HDE approval to commercialize the first deep brain stimulation (DBS) therapy for a psychiatric indication

55. Cer-238-Cervical-Ripening-Appendix-E-1 (xls file)
    effectivehealthcare.ahrq.gov/sites/default/files/cer-238-cervical-ripening-appendix-e-1.xlsx
    January 01, 2009 - NR) -Patients were seen weekly until the onset of spontaneous labor, the rupture of membranes or an indication … -Study drug delivered at 40 weeks if deemed appropriate (No indication of what constitutes "appropriate … ") - Study drug delivered at 41 weeks if deemed appropriate (No indication of what constitutes "appropriate … an obstetrician) -After insertion, patients were permitted to be ambulatory if there was no medical indication … 301 in outpatient group that were presumed large for gestational age, which is considered a medical indication

56. Identification and Treatment of Post-Acute Coronary Syndrome (ACS) Depression: A Systematic Review (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/acs-depression-research-protocol-amended.pdf
    February 15, 2017 - medications that are FDA- approved for treatment of major depressive disorder1 Drug FDA-Labeled Indication … Drug FDA-Labeled Indication … antipsychotics that are FDA-approved for treatment of major depressive disorder1 Drug FDA-Labeled Indication … Drug FDA-Labeled Indication … antidepressants that are FDA-approved for treatment of major depressive disorder1 Drug FDA-Labeled Indication

57. Arthritis and Nontraumatic Joint Disease (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-1506.pdf
    June 01, 2015 - Because secukinumab is approved for treating plaque psoriasis, its cost is available for that indication … , or TNF inhibitor therapy.7 The company has announced plans for regulatory submissions for an AS indication … and the company has also announced plans for regulatory submissions for a psoriatic arthritis (PsA) indication … to NSAIDs, DMARDs, or TNF inhibitor therapy.7 The company plans regulatory submissions for a PsA indication … The company has also announced plans for regulatory submissions for an ankylosing spondylitis (AS) indication

58. S158 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/s158.pdf
    October 01, 2007 - With respect to prescribed medications, this bias is called confounding by indication.2 It stems from … -7079/07/4500-0158 Medical Care • Volume 45, Number 10 Suppl 2, October 2007S158 confounding by indication … limitation makes the data from such analyses vulnerable to confounding bias, such as con- founding by indication … Confounding by indication. Epidemiology. 1996;7:335– 336. 3. Stürmer T, Hasselbach P, Amelang M.

59. Data Points 16: Types of Prostate Radiation: Changes across time and geography in the use of prostate radiation technologies for newly diagnosed older cancer patients: 2006-2008 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-radiation_research.pdf
    November 01, 2012 - national trends can be studied using Medicare claims alone with minimal worry about confounding due to indication … prostatectomy as minimally invasive or open if they had claims with select HCPCS codes, and NOS if the only indication

60. Test-Performance-Metrics Appendixes (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/test-performance-metrics_appendixes.pdf
    January 01, 2005 - These values are highly useful for clinical purposes because they give the clinician an indication of