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Showing results for "indication".
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41. Progestogens-Preterm-Birth Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/progestogens-preterm-birth_executive.pdf
    September 01, 2012 - Within each KQ, we organized the evidence by aspects of the question, such as indication and formulation … One unique indication, asymptomatic short cervix, had a randomized trial of progesterone vaginal gel … after completion of our initial systematic review, bringing the total number of women studied for this indication … Our update identified eight additional randomized trials, one for the indication of prior preterm birth … Use of progestogens for this indication is based on evidence of moderate strength, based on small numbers

42. Routine Preoperative Testing: Comparative Effectiveness Review | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/preoperative-testing/research-protocol
    May 14, 2013 - by the American Society of Anesthesiologists as those done in the absence of any specific clinical indication … preoperative testing may result in false-positive or borderline results (in the absence of a clinical indication … benefits and harms, namely, the risk of the surgical procedure, the type of anesthesia planned, the indication … and compare outcomes by: The risk of the surgical procedure, the type of anesthesia planned, the indication … include routine preoperative testing (testing done in everyone having a given surgery regardless of any indication

43. Refining Key Questions: Interactive Case Study Quiz
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/rfviia.pptx
    May 01, 2010 - of potential uses—prophylaxis, treatment, and end-stage—whereas the bar representing the off-label indication … Applicability diminished by mismatch between existing research and real-world patterns of indication … thereby compromised by small study size, use of indirect outcomes, and heterogeneity in dosage and indication … Mean Differences in Mortality and Thromboembolic Event Rates by Study and rFVIIa Indication This figure … but failed to show an effect of rFVIIa on other outcomes, including mortality. rFVIIa use for this indication

44. Refining Key Questions: Interactive Case Study Quiz
    effectivehealthcare.ahrq.gov/sites/default/files/rfviia.pptx
    May 01, 2010 - of potential uses—prophylaxis, treatment, and end-stage—whereas the bar representing the off-label indication … Applicability diminished by mismatch between existing research and real-world patterns of indication … thereby compromised by small study size, use of indirect outcomes, and heterogeneity in dosage and indication … Mean Differences in Mortality and Thromboembolic Event Rates by Study and rFVIIa Indication This figure … but failed to show an effect of rFVIIa on other outcomes, including mortality. rFVIIa use for this indication

45. Antiplatelet and Anticoagulant Treatments for Unstable Angina/Non-ST Elevation Myocardial Infarction | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/angina-heart-attack-treatments/research-protocol
    December 13, 2012 - of triple therapy , defined asdual antiplatelet therapy in patients with UA/NSTEMI who also have an indication … In patients with an indication for oral anticoagulant therapy, what are the risks and benefits of triple … In patients with an indication for long-term anticoagulant therapy, what are the comparative effectiveness … twice daily Oral (an intravenous formulation is commercially available) Approved No approved indication … twice daily Oral (an intravenous formulation is commercially available) Approved No approved indication

46. Kidney-Disease-Medicine Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-disease-medicine_executive.pdf
    January 01, 2012 - from CKD screening requires that the treatment benefits CKD populations who 3 would have had no indication … for such treatment in the absence of CKD or that, among patients with an indication for the treatment … Patients with hyperlipidemia and no coronary artery disease may not otherwise have an indication for … Patients with systolic CHF already have an indication for beta blockers, regardless of whether they … However, as patients with systolic CHF already have an indication for beta blocker treatment, testing

47. Comparative Effectiveness of Terbutaline Pump for the Prevention of Preterm Birth | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/preterm-birth-terbutaline-pump/research-protocol
    August 05, 2010 - x x Methods to control for important confounders 5 x Potential for confounding by indication … The methodology to assess ITT, loss to followup, and confounding by indication, is described in more … Assessment of Confounding by Indication: We consider the following factors salient for predicting the … (2) Potential for confounding by indication was removed from the quality assessment for all studies … How else would there be confounding by indication were it not because of differences in prognostic factors

48. Hematopoietic Stem-Cell Transplantation in the Pediatric Population | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/stem-cell-children/research
    February 01, 2012 - The strength of the body of evidence for each indication was assessed according to the process developed

49. Headaches in Pregnancy | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/get-involved/nominated-topics/topic-nomination-31814
    September 05, 2018 - important topic for review because although headaches during pregnancy can be benign, they can also be an indication

50. Rti-Item-Bank Research (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/rti-item-bank_research.pdf
    August 01, 2013 - Confounding from the indication of fetal distress makes it difficult to assess the independent effect … Norris et al. note the importance of selection bias and confounding by indication (confounding that … They are therefore at greater risk than RCTs for confounding by indication and selection bias. … Confounding by indication can occur from self-selection of treatments or physician-directed selection … Confounding by indication may also occur when the person allocating treatment is influenced by factors

51. S143 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/s143.pdf
    October 01, 2007 - Objectives: We sought to evaluate the ability of propensity score matching to mitigate confounding by indication … Chief among them is the indication for the drug—a patient must have the condition for which the drug … - lished.16,17 We sought to demonstrate what might happen when attempting to address confounding by indication … However, observational studies of efficacy must address concerns of bias—especially con- founding by indication

52. Topic Suggestion Description | Effective Health Care Program
    effectivehealthcare.ahrq.gov/get-involved/nominated-topics/description-of-a-question-or-questions-about-a-health-care-test-or-treatment-o-in-women-with-leiomyomas-who-are-candidates-for-surgery-does-the-use-of-adjunctive-medical-treatment-result-in-better-outcomes-preoperative-adjuva
    June 03, 2014 - Fibroids are the most common indication for hysterectomies, accounting for an estimated 40% of hysterectomies

53. Identification of Future Research Needs in the Comparative Management of Uterine Fibroid Disease | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/uterine-fibroids-2010/research
    March 10, 2011 - Limitations of the study may include confounding by indication. … include key predictive variables in multivariate analysis to minimize the effects of confounding by indication

54. Intermittent Inhalded Corticosteroids and Long-Acting Muscarinic Antagonists for Asthma (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-194-evidence-summary-corticosteroids-asthma.pdf
    October 01, 2017 - In this report, controller medications are defined by the timing and indication for use rather than … Likewise, for this report, quick relief therapy is defined by the timing and indication for use rather

55. Llewellyn-Thomas (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/llewellyn-thomas.pdf
    January 01, 2011 - . • End result is indication  of pt.’s overall favored option, at either the “coarse-­‐grained” or … www.effectivehealthcare.ahrq.gov/index.cfm) � • End result is also an indication

56. #06 Developmental Delays ADHD, and Autism (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/developmental-delays-horizon-scan-high-impact-1306.pdf
    June 01, 2013 - Manufacturers may have pursued regulatory approval of intranasal oxytocin for this indication, but … care for treating social dysfunction in ASDs, given the absence of other medication options for this indication … Laboratories, Ltd., of Tokyo, Japan, may have pursued regulatory approval of intranasal oxytocin for this indication … about a potential disparity in the use of the intervention in female patients (because an approved indication

57. Covariate Selection for Observational Comparative Effectiveness Research
    effectivehealthcare.ahrq.gov/sites/default/files/covariate-selection-chapter-7.pptx
    January 01, 2013 - Provider actions Confounding by indication: Prescribers choose treatments for patients who they believe … Sources of Confounding Sources of Confounding Provider Actions Confounding by indication Also referred … to as “channeling bias,” confounding by indication is common and often difficult to control in comparative … Confounding by indication and channeling over time: the risks of beta 2-agonists. … Confounding by indication: the case of calcium channel blockers.

58. DEMENTIA INCLUDING ALZHEIMER'S #04 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/dementia-horizon-scan-high-impact-1412.pdf
    February 01, 2015 - disease (AD), leading investigators to study serotonin-boosting drugs, such as citalopram, for this indication … searches of American and international registries found no significant ongoing clinical trials for this indication … Without additional clinical data, off-label use may be limited for this indication. … may address this unmet need, as a well-tolerated, potentially disease-modifying treatment for this indication … changes observed during intravenous administration.4,10 Consequently, most clinical trials for this indication

59. DEcIDE 33: Summary Variables in Observational Resesarch: Propensity Scores and Disease Risk Scores (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/observational-research-scores_research.pdf
    May 01, 2012 - ................................................................................. 1 Confounding by Indication … Confounding by Indication Confounding by indication is a specific type of confounding that is commonly … In some cases confounding by indication can be intractable. … Another problem with addressing confounding by indication arises when the indications are not adequately … Since LDL level is a primary indication for statin therapy and higher LDL levels are anticipated to

60. #05 DEPRESSION (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1312.pdf
    October 01, 2014 - FDA has granted fast-track status for this indication. … receptor might prevent excessive cortisol activity, potentially relieving PMD symptoms.11 For this indication … FDA has granted the agent fast-track status for this indication.1 FDA approved Korlym in 2012 for treating … These payers consider mifepristone investigational or unproven for this indication and do not provide … Manufacturers of scopolamine do not appear to be pursuing an official indication for treating depression