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181. Supplemental Project To Assess the Transparency of Reporting Requirements: Tympanostomy Tubes in Children With Otitis Media (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-tympanostomy_research.pdf
     June 01, 2017 - There is little indication of reporting bias in the papers, and in fact the only instance in which funding … Study outcomes information had highest number of discrepancies, potentially indication selective reporting

182. CER 220: Disposition of Comments Report for Comparative Effectiveness of Analgesics To Reduce Acute Pain in the Prehospital Setting (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-220-disposition-comments-analgesics-prehospital-setting.pdf
     September 03, 2019 - In our opinion, there was no indication that a change of 30-50% was superior to a 2-point change, nor … 27: I believe that the FDA has approved Intranasal Ketamine in the U.S., but perhaps not for this indication … Regarding discussion of Nitrous Oxide: Nitrous is an FDA approved product, but perhaps not for this indication

183. Pharmacologic and Nonpharmacologic Treatments for Posttraumatic Stress Disorder: An Update of the PTSD Repository Evidence Base (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-6-protocol.pdf
     December 07, 2024 - Pharmacologic and Nonpharmacologic Treatments for Posttraumatic Stress Disorder: An Update of the PTSD Repository Evidence Base Evidence-based Practice Center Systematic Review Protocol Project Title: Pharmacologic and Nonpharmacologic Treatments for Posttraumatic Stress Disorder: An Update of the PTSD Re…

184. Horizon Scanning Protocol and Operations Manual September 2015 Revision (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ahrq-healthcare-horizon-scan-protocol-operations-manual-151001.pdf
     September 01, 2015 - Is this a new and different clinical indication for an existing surgical procedure? If so, select. … Food and Drug Administration [FDA] approved) and the specific clinical indication for which they are … regulatory approval or, if not subject to FDA regulation, has diffused beyond early adopters for the indication … intervention; costs of the intervention; costs of a similar intervention for the same or another clinical indication … For example, in considering a new cardiac valve in development for a new clinical indication, we considered

185. Horizon Scanning Protocol and Operations Manual September 2015 Revision (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/ahrq-healthcare-horizon-scan-protocol-operations-manual-151001.pdf
     September 01, 2015 - Is this a new and different clinical indication for an existing surgical procedure? If so, select. … Food and Drug Administration [FDA] approved) and the specific clinical indication for which they are … regulatory approval or, if not subject to FDA regulation, has diffused beyond early adopters for the indication … intervention; costs of the intervention; costs of a similar intervention for the same or another clinical indication … For example, in considering a new cardiac valve in development for a new clinical indication, we considered

186. Major-Depressive-Disorder Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/major-depressive-disorder_executive.pdf
     December 01, 2015 - 1 Comparative Effectiveness Review Number 161 Nonpharmacological Versus Pharmacological Treatments for Adult Patients With Major Depressive Disorder Executive Summary Background Major depressive disorder (MDD)1 is the most prevalent and disabling form of depression, affecting more than 16 percent of U.S…

187. uterine-fibroids-protocol-160301 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/uterine-fibroids_research-protocol.pdf
     March 01, 2016 - uterine-fibroids-protocol-160301   Source: www.effectivehealthcare.ahrq.gov Published online: March 1, 2016 Evidence-based Practice Center Systematic Review Protocol Project Title: Management of Uter ine Fibroids I. Background and Objectives for the Systematic Review Topic background Most women will dev…

188. Disposition of Comments for Treatment To Prevent Fractures in Men and Women With Low Bone Density or Osteoporosis -- Update of a 2007 Report (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoporosis-bone-fracture_disposition-comments.pdf
     March 01, 2012 - Amgen requests that the complete indication, as specified in the Prolia® prescribing information, be … Inclusion of this full indication would provide a more complete characterization of the intended patient … We have added the full indication. … changes were nearly identical to the changes in women, and the drug was approved in men with the indication … The PMO study in women did show the effect of both vert and non-vert reduction and that is the indication

189. Medical Therapies for Children With Autism Spectrum Disorder—An Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/asd-medical-executive-170505.pdf
     May 01, 2017 - across studies; some studies amply described how harms were tracked, while others listed harms with no indication … across studies; some studies amply described how harms were tracked, while others listed harms with no indication

190. Undescended-Testicle Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/undescended-testicle_executive.pdf
     December 01, 2012 - Four studies provided data on LHRH compared with hCG, with no clear indication of either being better … Across all KQs, there is no indication that study populations are different from those in standard

191. Systematic Review of Intermittent Inhaled Corticosteroids and of Long-acting Muscarinic Antagonists for Asthma (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-pharmacologic-treatment_research-protocol.pdf
     December 27, 2016 - muscarinic antagonists Class Registered/Trademark (chemical name) Regulatory Agency Approved Indication … September 14, 2016; republished December 27, 2016 17 Class Registered/Trademark (chemical name) Indication

192. #14 SUBSTANCE ABUSE (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/14_substanceabuse_potential_high_impact_june_2012.pdf
     January 01, 2012 - month) when first approved for opioid addiction treatment, but reports of slow adoption for this indication … market. 24 According to the drug’s prescribing information, extended-release naltrexone for this indication

193. PULMONARY with "Discussions" in Exec Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1306.pdf
     June 01, 2013 - patients with CF are homozygous for that mutation, giving ivacaftor the potential for a much broader indication … G551S, G970R, G1244E, S1251N, S1255P, and G1349D.8,9 Thus, ivacaftor may gain a broader patient indication

194. Ch 1-User-Guide-To-Ocer 130129 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/ch_1-user-guide-to-ocer_130129.pdf
     August 13, 2012 - randomization might be needed, such as determining whether an FDA-approved drug can be used for a new use or indication … In this case, the FDA revoked their approval of the breast cancer indication for Avastin after concluding

195. Executive summary_Comparative Effectiveness Review No. 250_Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain: 2024 Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-2024-surv-rep-update-executive-sum.pdf
     January 01, 2024 - Executive summary_Comparative Effectiveness Review No. 250_Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain: 2024 Update Comparative Effectiveness Review Number 250 Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain: 2024 Update Exec…

196. Executive Summary_Systematic Review: Mental Health and Occupational Stress in the Emergency Medical Services and 911 Workforces (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ems-911-workforce-mental-health-executive-summary.pdf
     February 01, 2025 - Executive Summary_Systematic Review: Mental Health and Occupational Stress in the Emergency Medical Services and 911 Workforces Systematic Review M ental Health and Occupational Stress in the Emergency Medical Services and 911 Workforces Executive Summary Main Points • No study reported o…

197. Cer-243-Prehospital-Airway-Management-Appendix-F-1 0 (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-243-prehospital-airway-management-appendix-f-1_0.xlsx
     January 01, 2016 - vs. pediatric: 1.80 (95% CI 1.49–2.17) pediatric vs. adult: AOR 0.56 (95% CI 0.46 to 0.67), p<0.05 Indication … Adult: 84.6% vs. 89.8% AOR, adult vs. pediatric: 1.63 (95% CI 0.70–3.31) Indication, drug assistance, … association between success rates and patient gender, body mass index, age, cervical spine immobilization, indication … Patient gender, body mass index, age, cervical spine immobilization, indication for airway management … 0.82 (95% CI 0.40 to 1.70), p=0.60 Age, sex, intubation experience, trauma type, drugs administered, indication

198. Cer-238-Cervical-Ripening-Appendix-E-2 (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-238-cervical-ripening-appendix-e-2.xlsx
     January 01, 2017 - differences in Bishop score (stat sig); although not stat significant >10% diff in parity; Differences in indication … remain [statistically significant] after controlling for maternal age, parity, BMI, gestational age and indication … Logistic regression controlling for "maternal demographic and induction indication variables" done for

199. #14 SUBSTANCE ABUSE (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/substance-abuse-horizon-scan-high-impact-1406.pdf
     January 01, 2020 - Evzio also incorporates red and green light-emitting diodes (LEDs), providing an alternate visual indication … Attorney General and the World Health Organization for this indication;41,42 Naloxone can be delivered

200. 04-E029-1 Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer-surveillance_executive.pdf
     December 01, 2011 - Confounding by indication is likely in these studies, due to the differences in patient characteristics