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  1. effectivehealthcare.ahrq.gov/sites/default/files/developmental-delays-horizon-scan-high-impact-1512.pdf
    December 01, 2015 - recognizing a confluence, are concurrently investigating the drug’s utility for treating this second indication
  2. Ced -Appendix-2 (xls file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/ced%20-appendix-2.xlsx
    October 08, 2025 - Ban CED for on label indication FDA approved. … to this comment process Biogen Ban CED for drugs with accelerated approval Ban CED for on label indication
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/COVID-19-pharmaceutical-treatments.pdf
    December 23, 2023 - conduct a search on causality of adverse events associated with the interventions, regardless of medical indication
  4. PEPTIC ULCER #11 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/11_pepticulcer_potential_high_impact_june_2012.pdf
    January 01, 2012 - August 2011, ES-5 NPS began submitting data for a new drug application to FDA for the same indication … patient education would be necessary before this intervention would become widely diffused for this indication … treating SBS. 47 In December 2011 NPS completed submission of a new drug application for the same indication … 48,49 A decision is expected from FDA in September 2012. 50 Teduglutide is not approved for any indication
  5. #05 DEPRESSION (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1512.pdf
    December 01, 2015 - insufficient clinical trial evidence existed to support ketamine antidepressant efficacy for either indication … profiles and abuse risk, additional attendant resources and monitoring requirements, and lack of indication-specific … and off-label antidepressants, antipsychotics, and benzodiazepines are often prescribed for this indication … treatment option that could increase treatment rates and improve patient health outcomes for this indication
  6. Obesity (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1406.pdf
    June 01, 2014 - If priced similarly to the diabetes indication, this would provide 18, 3 mg doses at a cost of about … The approved indication is “as an adjunct to a reduced-calorie diet and increased physical ES- … The approved indication is as “an adjunct to a reduced-calorie diet and increased physical activity … Nonetheless, the manufacturer is pursuing a labeled indication for treating overweight and obesity. … If pricing is similar for the obesity indication, such a carton would provide 18 doses at the 3 mg
  7. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-217-infertility-evidence-summary.pdf
    May 01, 2019 - couples using frozen embryo versus fresh embryo transfer Low (1 study, heterogeneous infertility indication … couples using frozen embryo versus fresh embryo transfer Low (1 study, heterogeneous infertility indication … couples using frozen embryo versus fresh embryo transfer Low (1 study, heterogeneous infertility indication … couples using frozen embryo versus fresh embryo transfer Low (1 study, heterogeneous infertility indication … and other treatments which are used for multiple indications, reporting of results separately by indication
  8. effectivehealthcare.ahrq.gov/sites/default/files/pdf/hypothyroidism-hyperthyroidism-screening-treatment_research-protocol.pdf
    March 11, 2010 - Brand Name: Levo-T, Synthroid, Levothroid, Levoxyl, Unithroid); All drugs are FDA-approved for this indication … triiodothyronine (T3); Generic name: Liotrix (Brand name: Thyrolar) Thyrolar is FDA-approved for this indication
  9. effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-drugs-utilization-cost_research.pdf
    January 01, 2011 - continu- ously enrolled in Parts A and B throughout the calendar year while alive used biologics with an indication … Identification of Biologics Biologics included for study were limited to those having an indication
  10. effectivehealthcare.ahrq.gov/sites/default/files/pdf/benefits-harms-modeling_research.pdf
    November 19, 2009 - test gets into practice, health providers may start using it for increasingly broader indications (indicationIndication creep is not necessarily undesirable as long as there are no changes in the disease spectrum
  11. effectivehealthcare.ahrq.gov/sites/default/files/pdf/weight-loss-surgery_research-protocol.pdf
    December 14, 2010 - surgery devices, manufacturers, and FDA approved indications Device Manufacturer FDA Approved Indication … Pharmacologic Class Generic (Name brand) Manufacturer FDA Approved Indication(s)a GLP-1 receptor
  12. effectivehealthcare.ahrq.gov/sites/default/files/dementia-horizon-scan-high-impact-1312.pdf
    December 01, 2013 - AD and no particular company appears to be pursuing trials to secure FDA approval for a labeled indication … Currently, insulin manufacturers do not appear to be pursuing development of their products for this indication
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/infantile-hemangioma_disposition-comments.pdf
    January 15, 2016 - vary depending on clinical presentation and lesion characteristics, but the meta-analyses provides an indication … TEP reviewer #5 Discussion/ Conclusion ES-23/25-28- Neither of these is an indication for steroid … vary depending on clinical presentation and lesion characteristics, but the meta-analyses provides an indication
  14. Obesity (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/10_obesity_potential_high_impact_2012-12-11.pdf
    January 01, 2012 - The approved indication is “as an adjunct to a reduced-calorie diet and increased physical activity … mg (NN8022) is 4 in phase III trials for treating obesity; a new drug application for this indication … The approved indication is as “an adjunct to a reduced-calorie diet and increased physical activity
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/hemorrhage-postpartum_disposition-comments.pdf
    April 28, 2015 - proposed interventions in our algorithms and the almost impossible task of dealing with confounding by indication … whereas the other devices mentioned here (Foley, S-B tube, Rusch balloon) are not FDA-cleared for the indication … TEP Reviewer #1 Discussion/ Conclusion Methods for dealing with confounding by indication should
  16. effectivehealthcare.ahrq.gov/sites/default/files/pdf/preterm-birth-terbutaline-pump_research-protocol.pdf
    October 18, 2010 - The methodology to assess ITT, loss to followup, and confounding by indication, is described in more … (2) Potential for confounding by indication was removed from the quality assessment for all … How else would there be confounding by indication were it not because of differences in prognostic
  17. effectivehealthcare.ahrq.gov/sites/default/files/ch_11-user-guide-to-ocer_130129.pdf
    January 03, 2012 - In this study, the authors used past use to address indication, by comparing current users to past … users” should resemble that of the “nonusers”; if not, there is a possibility that confounding by indication … Assessment and control for confounding by indication in observational studies.
  18. effectivehealthcare.ahrq.gov/sites/default/files/pdf/echocardiography_research.pdf
    May 01, 2014 - unwarranted costs to the health care system.”12 The criteria vary by previous service and clinical indication … in gen- eral echocardiography testing is viewed as appropriate to assess conditions that have an indication … Second, claims data do not contain information about the indication for the procedure nor of the test
  19. effectivehealthcare.ahrq.gov/sites/default/files/vte-protocol-8-4-10.pdf
    February 01, 2008 - Pharmacologic Agents Pharmacol- ogic Class Generic (Name brand) Manufacturer FDA Approved Indication … Inferior Vena Cava Filters Name Manufacturer FDA Approved Indication(s) Stainless Steel Greenfield … Mechanical Devices Name Manufacturer FDA Approved Indication(s) Jobst® Anti-embolism Graduated
  20. effectivehealthcare.ahrq.gov/sites/default/files/pdf/blood-clots-hip-knee-surgery_research-protocol.pdf
    February 01, 2008 - Pharmacologic Agents Pharmacol- ogic Class Generic (Name brand) Manufacturer FDA Approved Indication … Inferior Vena Cava Filters Name Manufacturer FDA Approved Indication(s) Stainless Steel Greenfield … Mechanical Devices Name Manufacturer FDA Approved Indication(s) Jobst® Anti-embolism Graduated

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