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  1. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/breast-cancer-imaging_disposition-comments.pdf
    October 01, 2014 - Under “Indication for Imaging”, a criterion for exclusion is “Imaging used to detect recurrence following … There is no indication in the report, however, as to how these studies should be performed. … As this Brief reports, very little evidence exists on the use of imaging for this indication in this
  2. S58 (pdf file)

    effectivehealthcare-admin.ahrq.gov/sites/default/files/s58.pdf
    October 01, 2007 - Techniques such as propensity scoring and instrumental variables can help reduce confounding by indication … address bias due to unob- served clinical factors motivating prescription of treatments (“confounding by indication … treatment patterns that can be calculated from Medicaid data are probably less subject to confounding by indication
  3. effectivehealthcare-admin.ahrq.gov/products/methods-guidance-harms/methods
    May 01, 2020 - For unexpected adverse events, for example, confounding by indication may not be as important an issue … Such "confounding by indication" led to the appearance of an apparent association between selective NSAID … an important limitation of uncontrolled studies is that it is difficult to evaluate confounding by indication … Assessment and control for confounding by indication in observational studies.
  4. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-217-infertility-evidence-summary.pdf
    May 01, 2019 - couples using frozen embryo versus fresh embryo transfer Low (1 study, heterogeneous infertility indication … couples using frozen embryo versus fresh embryo transfer Low (1 study, heterogeneous infertility indication … couples using frozen embryo versus fresh embryo transfer Low (1 study, heterogeneous infertility indication … couples using frozen embryo versus fresh embryo transfer Low (1 study, heterogeneous infertility indication … and other treatments which are used for multiple indications, reporting of results separately by indication
  5. effectivehealthcare-admin.ahrq.gov/system/files/docs/headaches-pregnancy-topic-brief.pdf
    January 01, 2019 - epidural blood patch). 5 Although most headaches during pregnancy are benign, they can also be an indication … However, the search end date was November 2015, and HA indication was not mentioned. … important topic for review because although headaches during pregnancy can be benign, they can also be an indication
  6. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/COVID-19-pharmaceutical-treatments.pdf
    December 23, 2023 - conduct a search on causality of adverse events associated with the interventions, regardless of medical indication
  7. effectivehealthcare-admin.ahrq.gov/products/skin-lesions-evaluation/research-protocol
    December 01, 2019 - Provide a synthesis of the following information: Indication/patient inclusion criteria Type of
  8. Ced -Appendix-2 (xls file)

    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/ced%20-appendix-2.xlsx
    October 12, 2022 - Ban CED for on label indication FDA approved. … to this comment process Biogen Ban CED for drugs with accelerated approval Ban CED for on label indication
  9. #05 DEPRESSION (pdf file)

    effectivehealthcare-admin.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1512.pdf
    December 01, 2015 - insufficient clinical trial evidence existed to support ketamine antidepressant efficacy for either indication … profiles and abuse risk, additional attendant resources and monitoring requirements, and lack of indication-specific … and off-label antidepressants, antipsychotics, and benzodiazepines are often prescribed for this indication … treatment option that could increase treatment rates and improve patient health outcomes for this indication
  10. PEPTIC ULCER #11 (pdf file)

    effectivehealthcare-admin.ahrq.gov/sites/default/files/11_pepticulcer_potential_high_impact_june_2012.pdf
    January 01, 2012 - August 2011, ES-5 NPS began submitting data for a new drug application to FDA for the same indication … patient education would be necessary before this intervention would become widely diffused for this indication … treating SBS. 47 In December 2011 NPS completed submission of a new drug application for the same indication … 48,49 A decision is expected from FDA in September 2012. 50 Teduglutide is not approved for any indication
  11. Obesity (pdf file)

    effectivehealthcare-admin.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1406.pdf
    June 01, 2014 - If priced similarly to the diabetes indication, this would provide 18, 3 mg doses at a cost of about … The approved indication is “as an adjunct to a reduced-calorie diet and increased physical ES- … The approved indication is as “an adjunct to a reduced-calorie diet and increased physical activity … Nonetheless, the manufacturer is pursuing a labeled indication for treating overweight and obesity. … If pricing is similar for the obesity indication, such a carton would provide 18 doses at the 3 mg
  12. effectivehealthcare-admin.ahrq.gov/sites/default/files/dementia-horizon-scan-high-impact-1312.pdf
    December 01, 2013 - AD and no particular company appears to be pursuing trials to secure FDA approval for a labeled indication … Currently, insulin manufacturers do not appear to be pursuing development of their products for this indication
  13. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/weight-loss-surgery_research-protocol.pdf
    December 14, 2010 - surgery devices, manufacturers, and FDA approved indications Device Manufacturer FDA Approved Indication … Pharmacologic Class Generic (Name brand) Manufacturer FDA Approved Indication(s)a GLP-1 receptor
  14. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/cancer-drugs-utilization-cost_research.pdf
    January 01, 2011 - continu- ously enrolled in Parts A and B throughout the calendar year while alive used biologics with an indication … Identification of Biologics Biologics included for study were limited to those having an indication
  15. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/benefits-harms-modeling_research.pdf
    November 19, 2009 - test gets into practice, health providers may start using it for increasingly broader indications (indicationIndication creep is not necessarily undesirable as long as there are no changes in the disease spectrum
  16. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/hypothyroidism-hyperthyroidism-screening-treatment_research-protocol.pdf
    March 11, 2010 - Brand Name: Levo-T, Synthroid, Levothroid, Levoxyl, Unithroid); All drugs are FDA-approved for this indication … triiodothyronine (T3); Generic name: Liotrix (Brand name: Thyrolar) Thyrolar is FDA-approved for this indication
  17. effectivehealthcare-admin.ahrq.gov/products/blood-clots-hip-knee-surgery/research-protocol
    December 01, 2019 - Pharmacologic Agents Pharmacologic Class Generic (Name brand) Manufacturer FDA Approved Indication … Inferior Vena Cava Filters Name Manufacturer FDA Approved Indication(s) Stainless … Mechanical Devices Name Manufacturer FDA Approved Indication(s) Jobst® Anti-embolism
  18. effectivehealthcare-admin.ahrq.gov/products/COVID-19-pharmaceutical-treatments/research
    September 01, 2023 - conduct a search on causality of adverse events associated with the interventions, regardless of medical indication
  19. #14 SUBSTANCE ABUSE (pdf file)

    effectivehealthcare-admin.ahrq.gov/sites/default/files/substance-abuse-horizon-scan-high-impact-1506.pdf
    June 01, 2015 - conducted clinical trials investigating variations of interactive text messaging interventions for this indication … Office of the Attorney General and the World Health Organization for this indication.6,15-17 When naloxone … Prevention of Hazardous Alcohol Use Unmet need: Hazardous alcohol use is a composite substance abuse indication
  20. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/preoperative-testing_disposition-comments.pdf
    January 29, 2014 - preoperative testing may result in false positive or borderline results (in the absence of clinical indication … In this section, we describe how patient symptoms are an indication for testing. … urea, and pulmonary function tests before elective surgery in patients with no apparent clinical indication

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