-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/cancer-drugs-utilization_research.pdf
January 01, 2011 - with erlotinib orders had a prior
cancer diagnosis indicative of
its use in lung cancer (a labeled
indication … 165.x) in 84 percent of beneficiaries with
an order for the biologic, indicative of its
labeled indication
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/ischemic-stroke-treatment_executive.pdf
January 01, 2011 - Neurothrombectomy devices in use
Company In Clinical
Device Class Name FDA Indication Use? … Neurothrombectomy devices in use (continued)
Company In Clinical
Device Class Name FDA Indication Use
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/horizon-scan_research-2015.pdf
January 01, 2015 - For example, in
considering a new transcathether cardiac valve in development for a new clinical indication … median progression-free survival benefit
of weeks to a benefit of months or years, depending on the indication … However, this estimate assumes pembrolizumab receives an additional indication
as first-line treatment … Thus, its use is off-label for
this indication. … ; however,
another manufacturer continues to develop the Libra device for this indication.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/quality-rating_research.pdf
November 01, 2011 - No obvious difference was observed in the numbers of discrepancies, providing a first
indication that … criteria,” “clear reporting,” “blinded
observers,” and “dropout rate <20 percent,” which provided an indication … This may provide an indication that the
format of the article presentation (and not the exact amount … rates to >20 percent was a sufficient factor to downgrade 3 “B” quality
studies to “C,” providing an indication … However, it
should be noted that the 20 percent cutoff point as indication of “large” dropout is arbitrary
-
effectivehealthcare-admin.ahrq.gov/products/back-pain-imaging/clinician
November 01, 2017 - There was potential for confounding by clinical indication among study participants: patients who underwent
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-1512.pdf
December 29, 2015 - 6
Because secukinumab is approved for treating plaque psoriasis, its cost is available for
that indication … DMARDs, or TNF inhibitor therapy.9 The company submitted
global regulatory submissions for an AS indication … , as well as a psoriatic arthritis indication, in
2015.10
In January 2015, the U.S. … as well as
an ankylosing spondylitis (AS) indication.10
In January 2015, FDA approved secukinumab … yet approved for treating PsA, no coverage, coding, or payment
information is available for this indication
-
effectivehealthcare-admin.ahrq.gov/products/vte-prophyalaxis/research-protocol
December 01, 2019 - United States and either are FDA approved for VTE prophylaxis or are being used off label for this indication … aspirin and clopidogrel, as well as the anticoagulant warfarin, which may be used off label for this indication … Table 1: Pharmacologic agents and medical devices approved in the United States for some indication … 30 mg BID (30 mg for renal impairment)
Sanofi-Aventis; generic from Sandoz (2010)
1993
Dosing indication
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/cer-243-prehospital-airway-management-evidence-summary_0.pdf
June 01, 2021 - The most important limitations were weaker
observational study designs, rendering them vulnerable to indication
-
effectivehealthcare-admin.ahrq.gov/products/test-performance-metrics/appendixes
December 01, 2019 - These values are highly useful for clinical purposes because they give the clinician an indication of
-
effectivehealthcare-admin.ahrq.gov/products/hypothyroidism-hyperthyroidism-screening-treatment/research-protocol
December 01, 2019 - Brand Name: Levo-T, Synthroid, Levothroid, Levoxyl, Unithroid); All drugs are FDA-approved for this indication … triiodothyronine (T3); Generic name: Liotrix (Brand name: Thyrolar) Thyrolar is FDA-approved for this indication
-
effectivehealthcare-admin.ahrq.gov/products/renal-update/research-protocol
January 01, 2020 - now allow studies in which patients receive renal artery and aortic surgery, as long as the primary indication … e.g., “drive-by” angioplasty during coronary artery angiography, RAS angioplasty done as a secondary indication
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/vte-prophyalaxis_research-protocol.pdf
March 01, 2011 - United States and either are FDA approved
for VTE prophylaxis or are being used off label for this indication … aspirin and clopidogrel, as well as the anticoagulant warfarin, which may be
used off label for this indication … , 2012
Table 1: Pharmacologic agents and medical devices approved in the United States for some indication … BID (30 mg
for renal
impairment)
Sanofi-Aventis;
generic from
Sandoz (2010)
1993 Dosing indication
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-guidance-harms_methods.pdf
November 01, 2008 - For unexpected adverse events, for example, confounding by indication
may not be as important an issue … Such ―confounding by
indication‖ led to the appearance of an apparent association between selective … an important
limitation of uncontrolled studies is that it is difficult to evaluate confounding by indication … Assessment and control for confounding by
indication in observational studies.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/methodsguide_chou_assessing_harms_when_comparing.pdf
November 01, 2008 - For unexpected adverse events, for example, confounding by indication
may not be as important an issue … Such ―confounding by
indication‖ led to the appearance of an apparent association between selective … an important
limitation of uncontrolled studies is that it is difficult to evaluate confounding by indication … Assessment and control for confounding by
indication in observational studies.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-215-depression-older-adults-comments.pdf
March 28, 2019 - Thus, the authors conclude
“As this is an observational study, it is susceptible to
confounding by indication … #2
Discussion No, the implications are not balanced by a further discussion of
confounding by indication … discussion, findings relative to what is
known section, regarding the concept of
confounding by indication … My biggest concern is that there is little to no
mention of confounding by indication. … discussion, findings relative to what is
known section, regarding the concept of
confounding by indication
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/skin-lesions-evaluation_research-protocol.pdf
August 23, 2010 - Provide a synthesis of the following information:
i Indication/patient inclusion criteria
ii Type
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/developmental-delays-horizon-scan-high-impact-1512.pdf
December 01, 2015 - recognizing a confluence, are concurrently investigating
the drug’s utility for treating this second indication
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cancer-anemia-update_executive.pdf
April 01, 2013 - Although
radiotherapy is not an FDA-approved indication for ESA
use, those results were included because
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/13_pulmonary_potential_high_impact_2012-12-11.pdf
January 01, 2012 - mutation occurs in about 70% of patients with CF, giving ivacaftor the
potential for a much broader indication … G551S, G970R, G1244E, S1251N, S1255P, or G1349D.
8,9
Thus,
ivacaftor may gain a broader patient indication
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/renal-update_research-protocol.pdf
January 15, 2015 - now
allow studies in which patients receive renal artery and aortic surgery, as long as the
primary indication … e.g., “drive-by” angioplasty during coronary artery
angiography, RAS angioplasty done as a secondary indication