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81. Supplemental Project To Assess the Transparency of Reporting Requirements: Tympanostomy Tubes in Children With Otitis Media (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-tympanostomy_research.pdf
    June 01, 2017 - tympanometry, evaluation of tube occlusion, physical examination, and vital sign measurement Bold indicates … NCT01404611 indicates that ciprofloxacin and fluocinolone acetonide have the shortest time to cessation … NCT01908803 indicates that similar percentages had a sustained clinical cure at day 3. … The study record indicates that proportion of subjects with microbiological success at the day 8 visit

82. Radiotherapy-Proton-Beam Research (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/radiotherapy-proton-beam_research.pdf
    May 01, 2012 - Proton beam radiotherapy is a form of external beam radiation that offers better precision for localized dosage than other types of external beam radiotherapy. Because proton beams deposit most of their energy during the final portion of their trajectory, they diminish the risk of damage to tissue surrounding the t…

83. Ch 5-User-Guide-To-Ocer 130129 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/ch_5-user-guide-to-ocer_130129.pdf
    January 01, 2012 - 59 Abstract This chapter discusses considerations for comparator selection in observational comparative effectiveness research (CER). Comparison groups should reflect clinically meaningful choices in real world practice and be chosen based on the study question being addressed. Recognizing the implications and pote…

84. QR Medica Web Site (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/ebc-challenge-1stplace-qrmedica.pdf
    January 01, 2013 - Fluid with no sign of infection (Otitis Media with Effusion) Note: Not all ear pain indicates infection

85. Updating the Measurement Criteria for AHRQ’s National Healthcare Quality and Disparities Report (NHQDR) (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/updating-criteria-qdr-protocol-amendment.pdf
    December 28, 2023 - Updating the Measurement Criteria for AHRQ’s National Healthcare Quality and Disparities Report (NHQDR) Version 5 4/18/2019 1 Evidence-based Practice Center Technical Brief Protocol Project Title: Updating the Measurement Criteria for AHRQ’s National Healthcare Quality and Disparities Report (NHQDR) Init…

86. Cancer-Drugs-Utilization Research (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-drugs-utilization_research.pdf
    January 01, 2011 - Utilization of anticancer biologic products among Medicare beneficiaries, by diagnostic cancer subchapter, 2006-2009 Anticancer Biologics Data Points #7 Fewer than 50 percent of beneficiaries with bevacizumab orders had a cancer diagnosis in the prior 6 months. This was driven by the biologic’s off-label use …

87. Slide 1
    effectivehealthcare.ahrq.gov/sites/default/files/comparator-selection-in-observational-chapter-5.pptx
    January 01, 2013 - Slide 1 Comparator Selection in Observational Comparative Effectiveness Research Prepared for: Agency for Healthcare Research and Quality (AHRQ) www.ahrq.gov Comparator Selection in Observational Comparative Effectiveness Research This slide set is based on a user guide titled Developing a Protocol for Observation…

88. Layout 1 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/recombinant-factor-viia_executive.pdf
    May 01, 2010 - Layout 1 Background This report evaluates the level of evidence currently available to support the effectiveness and safety of using recombinant activated coagulation factor VII (rFVIIa) for clinical indications not approved by the U. S. Food and Drug Administration (FDA). rFVIIa is approved for a variety of uses i…

89. The Effectiveness and Risks of Long-Term Opioid Treatment of Chronic Pain (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-pain-opioid-treatment_executive.pdf
    September 19, 2014 - despite limited evidence showing long-term beneficial effects.8,9 In addition, accumulating evidence indicates … Key Question using the four key categories recommended in the AHRQ Methods Guide.30 A “high” grade indicates … A “moderate” grade indicates moderate confidence that the evidence reflects the true effect and further … A “low” grade indicates low confidence that the evidence reflects the true effect and further research … An “insufficient” grade indicates evidence either is unavailable or is too limited to permit any conclusion

90. Major-Depressive-Disorder Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/major-depressive-disorder_executive.pdf
    December 01, 2015 - Nevertheless, reliable evidence indicates that the comparative effectiveness of SGAs is similar.24 … Conclusions Overall, the available evidence indicates that SGAs and CBT do not differ significantly

91. EHC Protocol: Updating the Measurement Criteria for AHRQ's National Healthcare Quality and Disparities Report (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/updating-criteria-qdr-protocol.pdf
    September 06, 2023 - EHC Protocol: Updating the Measurement Criteria for AHRQ's National Healthcare Quality and Disparities Report Evidence-based Practice Center Technical Brief Protocol Project Title: Updating the Measurement Criteria for AHRQ’s National Healthcare Quality and Disparities Report (NHQDR) I. Background and Objectives…

92. Evidence Report on the (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/atypical-antipsychotics-off-label-update_research-protocol.pdf
    May 19, 2010 - analyses are scored so that more severely symptomatic persons have higher scores, a negative effect size indicates

93. Disposition of Comments Report for Evidence Report 215 Safety of Vaccines Used for Routine Immunization in the United States (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/vaccine-safety_disposition-comments.pdf
    January 01, 2020 - In the “vaccinated vs unvaccinated” tables, ** indicates statistical significance. … Table A lists the 2011 ACIP recommendations, as the table’s title now clearly indicates. … We have removed “the IOM report indicates that the evidence does not convincingly support or favor … Table 4 clearly presents each element with examples and indicates how each element is to be applied … The supportive text indicates that the table does not imply association with the vaccine but they list

94. Evidence-based Practice Center Systematic Review Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/cerebral-palsy-feeding_research-protocol.pdf
    June 12, 2012 - • Diplegia/diparesis usually indicates the legs are affected more than the arms; primarily affects … • Hemiplegia/hemiparesis indicates the arm and leg on one side of the body is affected. … • Triplegia/triparesis indicates three limbs are affected. … • Double hemiplegia/double hemiparesis indicates all four limbs are involved, but one side of the … • Tetraplegia/tetraparesis indicates that all four limbs are involved, but three limbs are more

95. Meditation Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/meditation_executive.pdf
    January 01, 2014 - The figure indicates the populations of interest, the meditation programs, and the outcomes that we … ↑ indicates that the meditation group improved relative to the control group (with a relative difference … ↓ indicates the meditation group worsened relative to the control group (with a relative difference … Ø indicates a null effect (with a relative difference generally less than 5% across trials). ↑↓ indicates

96. Stem-Cell-Children Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/stem-cell-children_executive.pdf
    February 01, 2012 - 1 Comparative Effectiveness Review Number 48 Hematopoietic Stem-Cell Transplantation in the Pediatric Population Executive Summary Background Hematopoietic stem-cell transplantation (HSCT) refers to a procedure in which hematopoietic progenitor cells, including repopulating stem cells, are infused to restore …

97. Technical Brief Disposition of Comments Report for Gene Expression Profiling for Predicting Outcomes in Stage II Colon Cancer (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/colon-cancer-gene-profiling_disposition-comments.pdf
    December 14, 2012 - This section has been reworded for further clarity; report indicates that “the GEP result may only … Report now describes nodes “assessed” and indicates this is now an important quality marker for colon … The report indicates that clinical utility has not been shown with data from peer-reviewed publications

98. Covariate Selection for Observational Comparative Effectiveness Research
    effectivehealthcare.ahrq.gov/sites/default/files/covariate-selection-chapter-7.pptx
    January 01, 2013 - Causal Models and the Structural Relationship of Variables (1 of 7) Treatment Effects The model indicates … The arrow connecting treatment assignment (A0) to the outcome (Y1) indicates that treatment has a causal … The unmeasured variable (U1) indicates this is a nonexperimental study.

99. Updating the Framework for AHRQ’s National Healthcare Quality and Disparities Report (NHQDR) (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/updating-framework-protocol.pdf
    September 06, 2023 - Updating the Framework for AHRQ’s National Healthcare Quality and Disparities Report (NHQDR) Evidence-based Practice Center Technical Brief Protocol Project Title: Updating the Framework for AHRQ’s National Healthcare Quality and Disparities Report (NHQDR) I. Background and Objectives for the Technical…

100. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/rotator-cuff-tear_disposition-comments.pdf
     October 05, 2010 - Although clinical assessment is part of the diagnostic work-up, the literature indicates that clinical … For each scale, it would be helpful to indicate the exact value that indicates better shoulder function