-
effectivehealthcare.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1312.pdf
December 01, 2013 - We present
summaries on three topics (indicated below by an asterisk) that emerged as having high-impact … Ivacaftor tablets are
indicated for oral administration, one 150 mg dose every 12 hours for patients … also
being evaluated in 10 other CFTR gene mutations known to cause CF, which could expand
the indicated … ivacaftor’s price is considered to be
the highest-cost drug therapy on the market today, the company indicated … One report indicated that hospitals in
Europe pay about $60,000 for each machine.60
Clinical Pathway
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/rapid-assessment-research-updates_research.pdf
September 15, 2008 - Using this approach, they determined that out of 17 guidelines, new evidence and expert assessment
indicated … Survival analysis indicated that
about half the guidelines were outdated in 5.8 years; at 3.6 years,
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/crohns-disease_disposition-comments.pdf
February 25, 2014 - Please note in the review that CZP is not indicated for the induction of remission of
Crohn’s disease … We
considered all drugs for induction
and maintenance, regardless of
how they are indicated. … For those
treatments that are not indicated for Crohn’s disease, the recommended doses evaluated in … Infliximab does have the following FDA indications in pediatric patients: INFLIXIMAB is
indicated for … As indicated above, we revised
the summary of key findings and
added a section offering a clinical
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ear-infection_disposition-comments.pdf
May 04, 2013 - We have indicated that we could not find studies
focused on subgroups (page ES-20, Research
Gaps): … We limited our discussion to
tympanoscentesis, pneumatic otoscopy, and
hearing loss; we also indicated … The strength of evidence
table in the results section indicated that there
were mixed findings for … We
have indicated in the research gaps the
methodological limitations of many studies. … We
have further indicated that use of a common
outcome protocol would facilitate pooling results.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/type-2-diabetes-medications-update_research-protocol.pdf
April 06, 2010 - Evidence-based Practice Center Systematic Review Protocol
Source: www.effectivehealthcare.ahrq.gov
Published Online: April 06, 2010
1
Evidence-based Practice Center Systematic Review Protocol
Project Title: Comparative Effectiveness and Safety of Oral Diabetes Medications for Adu…
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/atypical-antipsychotics-off-label-update_research-protocol.pdf
May 19, 2010 - Evidence Report on the
Source: www.effectivehealthcare.ahrq.gov
Published Online: May 19, 2010
Evidence-based Practice Center Systematic Review Protocol
Project Title: Efficacy and Comparative Effectiveness of Off-Label Use of Atypical
Antipsychotics – Update
I. Background and Objectives for the Sys…
-
effectivehealthcare.ahrq.gov/sites/default/files/study-design-considerations-chapter-2.pptx
January 01, 2013 - Considerations
Define exposure (treatments) of interest at start of followup Use an active comparator (indicated
-
effectivehealthcare.ahrq.gov/sites/default/files/s108.pdf
October 01, 2007 - Values less than 1 indicated bias away
from the null, values of 1 indicated an absence of bias, and
values … greater than 1 indicated bias toward the null.42 In
this simulation, confounding produced unadjusted
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/uterine-fibroids_research-protocol.pdf
March 01, 2016 - uterine-fibroids-protocol-160301
Source: www.effectivehealthcare.ahrq.gov
Published online: March 1, 2016
Evidence-based Practice Center Systematic Review Protocol
Project Title: Management of Uter ine Fibroids
I. Background and Objectives for the Systematic Review
Topic background
Most women will dev…
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-240-acute-pain-evidence-summary.pdf
December 01, 2020 - Low back pain (38 trials): Evidence indicated that there might be no difference
between an opioid versus
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/vte-prophyalaxis_research-protocol.pdf
March 01, 2011 - medical patients
Dalteparin sodium
(Fragmin
®
)
Subcutaneous 5,000 IU QD Eisai/Pfizer 1994 Indicated … sodium
(Innohep
®
)
Subcutaneous 3,500 IU QD to
4500 IU SC daily
LEO
Pharma/Celgene
2000 Indicated … Xa Inhibitors
Fondaparinux
(Arixtra
®
)
Subcutaneous 2.5 mg QD GSK 2001 Indicated … , 2012
prophylaxis
Rivaroxaban
(Xarelto
®
)
Oral 10 mg QD Johnson and
Johnson
2011 Indicated
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/tympanostomy-tubes-executive-170523.pdf
May 01, 2017 - The number of studies that include each comparison is indicated next to each edge (connecting lines with … The number of studies that include each comparison is indicated next to each edge (connecting lines with … The number of studies that include each comparison is indicated next to each edge
(connecting lines … At baseline, the generic and disease-specific health-related
quality-of-life scores indicated good quality
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/lifecycle-assessment-disposition-comments.pdf
November 20, 2024 - Manufacturer data in this
space
The figure has been revised to reflect the
type of data sources indicated … KI Reviewer #2 Findings [pg. 21, GQ3b, "Over half of the studies indicated
further LCA studies were … (just curious)
The majority of the studies that indicated
further studies were needed were
published … Peer reviewer #2 Findings On page 22, the first bullet point mentions that key
informants indicated
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/colon-cancer-gene-profiling_technical-brief.pdf
December 01, 2012 - three of the GEP assays:
ColoPrint® Colon Cancer Recurrence Assay and the OncoDefender-CRC assay, indicated … available within 7 to 10 days following receipt of the tumor sample and Oncotype DX® Colon
Cancer assay indicated … If so, the predictive assay would be used if the
prognostic result indicated high risk of recurrence … Input from Key Informants indicated that currently there is little use of GEP assays in the
clinical … Input from Key Informants indicated that current standard of care for stage II patients does
not include
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-2024-surv-rep-update-executive-sum.pdf
January 01, 2024 - Executive summary_Comparative Effectiveness Review No. 250_Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain: 2024 Update
Comparative Effectiveness Review
Number 250
Living Systematic Review on Cannabis
and Other Plant-Based Treatments for
Chronic Pain: 2024 Update
Exec…
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ems-911-workforce-mental-health-executive-summary.pdf
February 01, 2025 - Executive Summary_Systematic Review: Mental Health and Occupational Stress in the Emergency Medical Services and 911 Workforces
Systematic Review
M
ental Health and Occupational Stress in
the Emergency Medical Services and 911
Workforces
Executive Summary
Main Points
• No study reported o…
-
effectivehealthcare.ahrq.gov/sites/default/files/s13.pdf
October 01, 2007 - ORIGINAL ARTICLE
Methodologic Challenges to Studying Patient Safety and
Comparative Effectiveness
Brian L. Strom MD, MPH
Abstract: Studies of patient safety and comparative effectiveness
entail unique methodologic challenges. These studies may be sus-
ceptible to systematic error, including selection bias, exposure
…
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-usability-testing.pdf
November 01, 2018 - Interviewees liked the key messages
and indicated that these should be on the first page. … Interviewees
indicated that the colors of the products were appealing; however, summaries should also … No change, as participants
indicated they liked the white
space that the combination of
images and … One non-
researcher indicated that although the page did not
resonate very well with them, they could … Number of studies and
participants contributing to each meta-
analysis is indicated.
-
effectivehealthcare.ahrq.gov/sites/default/files/diabetes-horizon-scan-high-impact-1406.pdf
September 26, 2014 - We present five summaries on topics (indicated below by an asterisk) that
emerged as having higher-impact … Reports in Europe have indicated
that insulin degludec has cost 60% to 70% more than competitors on … Reports from Europe have indicated that insulin
degludec costs 60% to 70% more than competitors on … In February 2011, the Lap-Band
received approval for the labeling change, which indicated its use for … The FDA has
indicated that Alimera will need to conduct two additional clinical trials to
demonstrate
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cystic-fibrosis-hgh_research-protocol.pdf
August 22, 2008 - Evidence-based Practice Center Systematic Review Protocol
Source: www.effectivehealthcare.ahrq.gov
Published Online: January 22, 2010 1
Evidence-based Practice Center Systematic Review Protocol
Project Title: Effectiveness of Recombinant Human Growth
Hormone in the Treatment of Cystic Fibrosis…