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effectivehealthcare.ahrq.gov/sites/default/files/related_files/suicidal-thoughts-young-people-amendement-may-2025.pdf
January 01, 2025 - Evidence-based Practice Center Systematic Review Protocol
Project Title: Management of Suicidal Thoughts and Behaviors in Youth
Initial Publication Date: May 2, 2024
Amendment Date(s): February 5, 2025, May 6, 2025
(Amendments Details-see Section VII)
I. Background and Objectives for the Systematic Review
…
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/main-apps-surv-report-2-acute-pain.pdf
May 01, 2022 - Systematic Review on Treatments for Acute Pain: Surveillance Report 2
Systematic Review on Treatments for
Acute Pain: Surveillance Report 2
Literature Update Period: November 1, 2021, through January 22, 2022
Background and Purpose
This is the second surveillance report for the 2020 report Treatments for Acute P…
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-disease-medicine_disposition-comments.pdf
August 01, 2012 - regarding whether systematic
screening of non-diabetic adults for CKD improves clinical
outcomes or increases … Published Online: January 2012
6
Commentator &
Affiliation Section Comment Response
outcomes or increases … Stages 1 to 3 CKD
conferred significant increases in the relative risk of all 5
parameters assessed … Essentially, the risk of adverse cardiovascular events
increases in proportion to the level of albuminuria … If one were to
screen for macroalbuminuria, which clearly increases risk of
progression to ESRD, then
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/acs-pci-adjunctive-devices_surveillance.pdf
April 01, 2013 - CER #42:
Adjunctive Devices for Patients With Acute Coronary
Syndrome Undergoing Percutaneous Coronary
Intervention
Original release date:
December, 2011
Surveillance Report:
May, 2013
Key Findings:
- There have been relatively few new studies, and those that
have been published report results consi…
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetes-drugs-utilization_research.pdf
March 01, 2011 - Utilization of antidiabetic drugs among Medicare
beneficiaries with diabetes, 2006-2009
Diabetes Treatment Data Points #9
Biguanides (i.e., metformin)
were the most commonly used
antidiabetic drug class among
Medicare beneficiaries from 2006 to
2009, followed by sulfonylureas,
insulins, and thiazolidinediones…
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/abnormal-uterine-bleeding_executive.pdf
March 01, 2013 - Prevalence
increases with age, reaching 24 percent
in women aged 36 to 40.1,2 Women
generally present … NSAID use selectively increases the risk of non-fatal myocardial
infarction: a systematic review of
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effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/white-paper-library-asthma.pdf
April 01, 2019 - Standardized Library of Asthma Outcome Measures
Research White Paper
Standardized Library of Asthma Outcome Measures
Research White Paper
Standardized Library of Asthma Outcome Measures
Prepared for:
Agency for Healthcare Research and Quality
Center for Outcomes and Ev…
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effectivehealthcare.ahrq.gov/sites/default/files/introduction-user-guide-to-ocer_130129.pdf
April 26, 2012 - 1
Introduction to Developing a Protocol for Observational
Comparative Effectiveness Research: A User’s Guide
Scott R. Smith, Ph.D.
Agency for Healthcare Research and Quality, Rockville, MD
Background
When making health care decisions, patients, health
care providers, and policymakers routinely seek
unbiased inf…
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/antidepressants-seniors-pneumonia_research.pdf
May 01, 2008 - Conclusion: These findings refute the prior hypothesis that use of antidepressants by elderly
patients increases
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/arthritis-psoriatric_surveillance.pdf
March 01, 2013 - led to higher rates of withdrawals because of
adverse events, diarrhea, and clinically
significant increases … Do Not Know
increases in alanine aminotransferase.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-disease-ace-inhibitor-arb_surveillance.pdf
July 06, 2015 - Untitled
AHRQ Comparative Effectiveness Review
Surveillance Program
CER #18: Comparative Effectiveness of Angiotensin
Converting Enzyme Inhibitors or An…
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effectivehealthcare.ahrq.gov/sites/default/files/07_diabetes_potential_high_impact_2012-12-10.pdf
January 01, 2012 - typically once per day plus a short-acting insulin
with meals (prandial insulin) to cover postmeal increases
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effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/methods-guide-inclusion-nonrandomized-studies.pdf
September 01, 2022 - Has the topic evolved in a way that increases or decreases the value of NRSIs? … a few RCTs may be available, and where they exist, are likely to
be narrow in scope, all of which increases … these issues.
1.2.5 Methods To Use When NRSIs Are Included
Inclusion of NRSIs (in addition to RCTs) increases … conclusion that selection of active comparator therapies with similar indications and
use patterns increases … o Has the topic evolved in a way that increases or decreases the value of NRSIs?
2.
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effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/methods-guide-inclusion-nonrandomized-studies.pdf
September 01, 2022 - Has the topic evolved in a way that increases or decreases the value of NRSIs? … a few RCTs may be available, and where they exist, are likely to
be narrow in scope, all of which increases … these issues.
1.2.5 Methods To Use When NRSIs Are Included
Inclusion of NRSIs (in addition to RCTs) increases … conclusion that selection of active comparator therapies with similar indications and
use patterns increases … o Has the topic evolved in a way that increases or decreases the value of NRSIs?
2.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/hip-fracture-pain.ppt
May 01, 2011 - No. 11-EHC022-EF
http://effectivehealthcare.ahrq.gov/hippain.cfm
The incidence of hip fracture increases … Health Impact in the United States of Hip Fracture From Low-Impact Injury
The incidence of hip fracture increases … The incidence increases approximately 30-fold for men and 50-fold for women in age groups from 50 to
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effectivehealthcare.ahrq.gov/sites/default/files/hip-fracture-pain.ppt
May 01, 2011 - No. 11-EHC022-EF
http://effectivehealthcare.ahrq.gov/hippain.cfm
The incidence of hip fracture increases … Health Impact in the United States of Hip Fracture From Low-Impact Injury
The incidence of hip fracture increases … The incidence increases approximately 30-fold for men and 50-fold for women in age groups from 50 to
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effectivehealthcare.ahrq.gov/sites/default/files/11_pepticulcer_potential_high_impact_june_2012.pdf
January 01, 2012 - Long-term PN can lead to serious side effects such as liver
damage, the risk of which increases the … parenteral nutrition (PN) can lead to serious side effects such as liver damage, the risk of
which increases … enhance the surface
area of the intestine or lengthen the time food spends in the intestines, which increases
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/back-pain-treatment_clinician.pdf
November 01, 2016 - Noninvasive Treatments for Low Back Pain: Current State of the Evidence
Noninvasive Treatments for Low Back Pain:
Current State of the Evidence
Focus of This Summary
This review examines the evidence on the comparative benefits and harms of noninvasive treatments for acute, subacute,
and chronic low back pain fro…
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effectivehealthcare.ahrq.gov/sites/default/files/06_devdelays_potential_high_impact_2012-12-10.pdf
January 01, 2012 - #06 Developmental Delays ADHD, and Autism
AHRQ Healthcare Horizon Scanning System – Potential
High-Impact Interventions Report
Priority Area 06: Developmental Delays, ADHD,
and Autism
Prepared for:
Agency for Healthcare Research and Quality
U.S. Department of Health and Human Services
540 G…
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/ced%20-appendix-2.xlsx
October 08, 2025 - Summary_Out of Scope Comments
There were many comments that were outside of the scope of this project in that they addressed the CED process rather including when and how it should be implemented. Multiple comments proposed that AHRQ should undertake a similar exercise to this one, with the goal of revising the CED p…