-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/vitamin-d-calcium_executive.pdf
September 01, 2014 - Three cohort studies and the nested
case-control study observed a trend toward increased
risk with … The nested case-control found lower risk of increased
mammographic density with 25(OH) concentrations … An association
was seen between lower 25(OH)D concentrations and
increased risk for falls over a year … However, borderline
nonsignificant associations were found for three outcomes,
suggesting increased … Taken together, six cohort studies of calcium intake suggest
that in populations at relatively increased
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/diagnostic-error-executive-summary.pdf
August 01, 2023 - usually found to be lower in
academic/teaching hospitals, but it is unknown if this is an effect of increased … The strongest, most consistent predictors of ED diagnostic error were individual
case factors that increased
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/topic-brief2-opioid-withdrawal.pdf
April 01, 2021 - management for individuals entitled to Medicare benefits.1
Issue
Use of opioid medications has increased … • Observational studies found that opioid discontinuation might be associated with
increased risk … Background
Use of opioids has increased in older patients and other individuals entitled to Medicare … who were using long-term opioids, the annual percentage who
underwent tapering of their daily dosage increased … Two retrospective
cohort studies found that discontinuation of opioids was associated with increased
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/topic-brief2-opioid-withdrawal.pdf
April 01, 2021 - management for individuals entitled to Medicare benefits.1
Issue
Use of opioid medications has increased … • Observational studies found that opioid discontinuation might be associated with
increased risk … Background
Use of opioids has increased in older patients and other individuals entitled to Medicare … who were using long-term opioids, the annual percentage who
underwent tapering of their daily dosage increased … Two retrospective
cohort studies found that discontinuation of opioids was associated with increased
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-247-interventional-treatments-acute-chronic-pain-evidence-summary_0.pdf
September 01, 2021 - • Vertebroplasty was not associated with increased risk of incident vertebral fracture at
12 months … 7 trials, N=826); evidence on serious adverse events was
sparse and imprecise but did not indicate increased … Effect size: none (i.e., no effect/no statistically significant effect), small, moderate, or large increased
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/tx-for-localized-prostate-cancer_surveillanceassesment_20120614.pdf
May 01, 2012 - therapy to RP did not
improve survival or cancer
recurrence rates, defined by PSA
recurrence, but increased … SCEPC
the higher dose of EBRT with a
combination of conformal
photon and proton beams
without increased … risk of genitourinary
complications, increased
incontinence, and increased
erectile dysfunction. … Through 12/2005 Treatment with GnRH
agonists was associated with
increased risk of diabetes,
coronary … Combined androgen blockade
and orchiectomy were
associated with increased risk
of coronary heart disease
-
effectivehealthcare.ahrq.gov/sites/default/files/tx-for-localized-prostate-cancer_surveillanceassesment_20120614.pdf
May 01, 2012 - therapy to RP did not
improve survival or cancer
recurrence rates, defined by PSA
recurrence, but increased … SCEPC
the higher dose of EBRT with a
combination of conformal
photon and proton beams
without increased … risk of genitourinary
complications, increased
incontinence, and increased
erectile dysfunction. … Through 12/2005 Treatment with GnRH
agonists was associated with
increased risk of diabetes,
coronary … Combined androgen blockade
and orchiectomy were
associated with increased risk
of coronary heart disease
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-263-postpartum-hypertensive-pregnancy-executive-summary.pdf
May 01, 2023 - Rates of HDP are rising
in the United States,1, 2 likely due to increased prevalence of pre-existing … event)
Recurrent seizure
(eclampsia)
✓ ✓
Loading dose only MgSO4
regimens probably result in
increased … risk of recurrent seizure
✓
Lower dose MgSO4 regimen may
result in increased risk of recurrent
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-cancer-medications_appendixes.pdf
March 01, 2009 - Do traditional Gail model risk
factors account for increased breast cancer in women with lupus? … Increased risk for cancer in patients with
the Peutz-Jeghers syndrome. … Current comprehensive assessment
and management of women at increased risk for breast cancer. … Identifying and counseling women at increased risk for breast cancer. … Reducing the risk of breast cancer with tamoxifen in women at increased risk.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/heart-failure-transition-care_clinician.pdf
October 01, 2015 - Emergency room (ER) visits: Evidence was insufficient to
determine if transitional care interventions increased … severity, or
coexisting conditions.
�� No trial assessed whether transitional care interventions
increased
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-238-cervical-ripening-evidence-summary.pdf
March 01, 2021 - evidence that outpatient cervical ripening with dinoprostone and single-balloon catheters
does not impose increased … We also found no indications of
important signals of increased risk of fetal/neonatal and maternal harms
-
effectivehealthcare.ahrq.gov/sites/default/files/asthma-self-mgmt-summary.pdf
April 01, 2020 - AS-ME packages generally improved asthma
control, reduced symptom frequency, increased
asthma knowledge
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hro-rapid-research.pdf
May 01, 2025 - In the post-
intervention period, Truman’s CR
increased to meet the All VHA 50th
percentile. … All VHA low-harm
event reporting rates also increased from 201.7 to
224.4 (p<0.001). … The All
VHA SSER significantly increased from 0.6 to 1.0
events per 10,000 Veterans (p<0.001). … Although the SMR and CR both increased post-
intervention, the post-intervention period was short and … They also argued that a mature safety culture will be accompanied by increased
safety event reporting
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/gerd-disposition-120104.pdf
April 01, 2011 - “An increased risk of bone fracture is now
added to this list, although the strength of association … neglect a discussion of long-term proton pump inhibitor
(PPI) use and its effect on bone weakness, increased … May 2010, the FDA issued a
consumer update regarding a possible increased risk of bone
outcomes, we … ) PPIs.15 According to the consumer update; the FDA
has evaluated 7 published studies reporting an increased … The risk of fracture was increased in patients who received
high-dose, defined as multiple daily doses
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/allergy-seasonal_disposition-comments.pdf
July 17, 2013 - the treatment comparisons, only head-to-head RCTs were
selected; uncontrolled studies are prone to increased … Similarly
to the statement about efficacy above lack of evidence of
increased harm is not equal to … evidence of no increased harm. … TEP #8 Introduction,
page 3, line 20
and increased intraocular pressure
J Allergy Clin Immunol. 2005 … Text revised in Background sections of ES and Full Report:
“Adverse local effects may include increased
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/acs-depression-research-protocol-amended.pdf
February 15, 2017 - Patients with depression post-MI have significantly increased risk of death.15
Despite the high prevalence … and appropriate follow up.”16 However, other guidelines
recommend targeted screening for patients at increased … to Adults with Cardiovascular
disease
Warnings:
All antidepressants have a black box warning for increased … Black box warning for increased risk of death in elderly patients with dementia-related
psychosis. … likely
not relevant to use in depression)
Other risks: akathisia, sedation, dizziness,
headache, increased
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-pci-bypass_executive.pdf
October 01, 2007 - In large registries, procedural survival has increased
significantly over time. … PCI increased along with the proportion of internal
mammary artery grafts used, but this trend was not … First, the number
of patients and outcome events would be greatly
increased, thereby improving statistical … was no evidence suggesting that hypertension, tobacco
use, renal dysfunction, and vascular disease increased … Use of mammary arteries Weak - Internal mammary artery use increased over time.
Table B.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/recombinant-factor-viia_executive.pdf
May 01, 2010 - • There was an increased rate of arterial
thromboembolic events with rFVIIa use vs. usual
care for … Regarding subpopulations of patients, our findings
include:
• Patients with coagulopathy may have increased … • Time from end of cardiopulmonary bypass to
chest closure was increased significantly in rFVIIa
patients … Thromboembolic events are increased by use of rFVIIa
in intracranial hemorrhage and adult cardiac surgery … Despite this state of evidence, in-hospital, off-label
cases of rFVIIa use have increased in the last
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/autism-adolescents_executive.pdf
August 01, 2012 - individuals with autism.10 A study of
health care utilization in a large group health plan revealed
increased … studies of antipsychotic
medications included sedation, gastrointestinal complaints,
weight gain, increased … Reading
comprehension30
Insufficient • 1 poor quality RCT; two facilitation methods increased comprehension … Finally, none of the studies examined whether
increased employment rates or improvements in other
outcomes … Increased use of such standardized age
groupings would facilitate comparisons of effectiveness
within
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/suicidal-thoughts-young-people-amendement-may-2025.pdf
January 01, 2025 - into young adulthood.1, 2 In the United States,
mortality rates associated with suicide have steadily increased … depressive disorder (MDD).19, 20 However, meta-analyses
of SSRI studies suggest a small but significant increased … in adolescents, leading the U.S Food and Drug Administration to institute a black box warning
for increased … risk by PHQ-9, C-SSRS, or ASQ
o Those who are from racial/ethnic minority
groups known to have increased