-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-anemia-update_research-protocol.pdf
June 16, 2010 - head and neck, anemia is reportedly a
prognostic factor.16 There is evidence that anemia, causing increased … Mortality and/or Increased Risk of
Tumor Progression or Recurrence) … WARNINGS: INCREASED MORTALITY, SERIOUS CARDIOVASCULAR
EVENTS, THROMBOEMBOLIC EVENTS, STROKE and INCREASED … At the same time, evidence is consistent with
an increased risk of thromboembolic events and mortality … Most fundamental
is the balance of potential benefits (QoL, fewer transfusions) and harms (increased
-
effectivehealthcare.ahrq.gov/sites/default/files/diabetes-update-2015_executive.pdf
January 01, 2015 - We found moderate strength of evidence that sulfonylureas
had an increased risk of severe hypoglycemia … Increased heart rate is associated with increased
mortality.38 However, whether heart rate is an independent … Safety Outcomes
Severe hypoglycemia is associated with increased
morbidity (e.g., reduced cognition … ), increased avoidable
health care use (e.g., emergency room visits for
hypoglycemia), and increased … SAVOR-TIMI 53,
TECOS, and EXAMINE all reported increased incidence
of acute pancreatitis with DPP-4
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/nursing-staff-shortages-rapid-research.pdf
April 01, 2025 - , decreased safety events, decreased hospital
length of stay, decreased registered nurse turnover, increased … Post-intervention, satisfaction improved,
wellbeing increased by 2.4 to 2.9 points on the Press Ganey … Nursing staff ratios
increased by 0.33 (2014), 0.42 (2015), and 0.46 (2016) registered nurse hours per … satisfaction,25 increased nursing time of
58 minutes per patient day,34 and a reduction in injury by … Staffing
Models: Making Increased Acuity Safe in the
Pediatric ICU.
-
effectivehealthcare.ahrq.gov/sites/default/files/decide16final-mortality-risk-in-copd-pts-using-theophylline.pdf
December 01, 2009 - When summarized by regimen, THEO patients were at increased risk of death
(Figure 2). … Importantly, in several cases theophylline was associated with an increased risk
of events; however, … these increased risks were generally small (HR of 1.1 to 1.3). … In the time-varying exposure analysis
ipratropium was associated with increased risk of mortality. … An overriding concern is that the increased risk of events with theophylline may be a
result of disease
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/copd-management_research.pdf
December 01, 2009 - When summarized by regimen, THEO patients were at increased risk of death
(Figure 2). … Importantly, in several cases theophylline was associated with an increased risk
of events; however, … these increased risks were generally small (HR of 1.1 to 1.3). … In the time-varying exposure analysis
ipratropium was associated with increased risk of mortality. … An overriding concern is that the increased risk of events with theophylline may be a
result of disease
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c_disposition-comments.pdf
November 27, 2012 - As will be discussed below,
the abstract states that boceprevir is associated with
increased risk of … This increased risk goes unmentioned in
several places in the document in which increased
hematological … Results (p.43) Triple therapy with Telaprevir was associated with
increased risk of anemia. … This increased risk goes
unmentioned in several places in the document,
noted above, in which increased … Discussion (p.61) Page 61: "On the other hand, triple therapy regimens
were associated with increased
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-stone-prevention_disposition-comments.pdf
July 26, 2012 - to the comment on radiation
exposure, we agree that patients with kidney
stones may be at risk for increased … We
revised our introduction to state that genetic
and anatomical factors also contribute to
increased … report both were revised to address
the role of inherited and anatomic factors in
contributing to increased … bran
and low purine increased risk of recurrent
stones versus a control diet.” … For two one additional treatment comparisons
(radiographic recurrence outcome for
increased fluid vs
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/gestational-diabetes-screening-diagnosis_research-protocol.pdf
December 16, 2011 - depending on population characteristics, such as ethnicity and clinical
status.
3,4
GDM incidence has increased … impaired glucose tolerance may affect
maternal and fetal health outcomes.
5
Mothers may face an increased … risk of labor and birth
complications, psychological issues, and an increased likelihood of developing … women who meet
all of the following criteria: age less than 25 years, not from an ethnic group with increased … A recent study found that the IADPSG criteria increased GDM
prevalence nearly threefold compared with
-
effectivehealthcare.ahrq.gov/sites/default/files/jensen_eccs2012.pdf
January 01, 2012 - sensation
• A parental rights issue
• Seeing the health care system
as “other”
Slide 8: Solutions
• Increased
-
effectivehealthcare.ahrq.gov/sites/default/files/moyer_eccs2012.pdf
January 01, 2012 - Firestorm: Outcomes
• Greater situational awareness
• Greater recognition of who the audience is
• Increased … Involvement
of communications specialists
• “Top Line”
messaging for
each recommendation
o Increased
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/epilepsy-medicine_surveillance.pdf
August 01, 2012 - The time to first seizure was increased for newer
antiepileptic medications versus phenytoin, but not … There is new safety
information for tegretol
(carbamazepine): serious
dermatologic reactions,
increased … Factors associated with poor seizure control
and increased side effects after switching to
generic … Generic
substitution of levetiracetam resulting in
increased incidence of breakthrough
seizures. … The time to first seizure was
increased for newer antiepileptic medications versus
phenytoin, but not
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/epilepsy-medicine_surveillance.pdf
August 01, 2012 - The time to first seizure was increased for newer
antiepileptic medications versus phenytoin, but not … There is new safety
information for tegretol
(carbamazepine): serious
dermatologic reactions,
increased … Factors associated with poor seizure control
and increased side effects after switching to
generic … Generic
substitution of levetiracetam resulting in
increased incidence of breakthrough
seizures. … The time to first seizure was
increased for newer antiepileptic medications versus
phenytoin, but not
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/phenylketonuria_surveillance.pdf
January 15, 2013 - Higher lifetime Phe and IDC
were associated with
increased visual evoked
potential latencies and … one
longitudinal study, The Maternal
PKU Collaborative Study,
provide support for the observed
increased … In the RCT, at a dosage
of 20
mg/kg/day over 10 weeks,
participants in the treatment group
increased … BH4-resistant
participants, who consumed
increased Phe during Phase 2,
never regained their original … In the RCT, at a dosage of 20
mg/kg/day over 10 weeks, participants in
the treatment group increased
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/c-diff-infections_research-protocol.pdf
May 24, 2010 - Clostridium difficile associated disease (CDAD) rates in the United States (and globally)
have increased … pregnant women, and other healthy adults.9 Characteristics
associated with hypervirulent strains include increased … Pepin24 suggests that both vancomycin and metronidazole are implicated in increased
frequency of vancomycin-resistant … Delayed treatment response
Treatment for pt w/ false +
No treatment for pt w/ false -
Increased … resolution of
diarrhea (choice of faster
working treatment)
Harms
Treatment of false
positives
Increased
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/gout_consumer.pdf
January 01, 2017 - Prednisone and
triamcinolone
��Fluid retention
(body tissues hold
extra water)
��Mood changes
�� Increased … Warnings
Medicines to lower uric acid
Allopurinol
(Zyloprim®)
��Nausea
��Diarrhea
��Skin rash
�� Increased … Febuxostat
(Uloric®)
��Nausea
��Skin rash
��Joint pain (not caused by gout)
�� Increased risk of a
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-218-osteoporosis-disposition-comments.pdf
April 23, 2019 - However, RCTs have not indicated that either AFF or
ONJ occur at increased risk; only observational … studies
suggest increased risk. … An increased risk of
heart attacks has not been associated with any
bisphosphonates or with denosumab … General Public Commenter
#7 (ASBMR)
Data are available of an increased risk of AFF and ONJ
with longer … Should be changed to “are associated with an increased
risk”.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/Evidence%20Summary_0_0.pdf
April 01, 2020 - and those without depressive
disorders whom the Food and Drug Administration
included in finding an increased … These warnings stemmed
from reports of possible increased risk of suicidal
ideation and suicide attempts … associated with
one SSRI, paroxetine, as well as the possibility of
increased risk of suicidality … With high risk-of-bias studies,
the evidence suggests increased risk of harms. … SSRIs may be associated with
increased withdrawal and serious AEs.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoporosis-bone-fracture_disposition-comments.pdf
March 01, 2012 - This document noted the importance of
animal safety testing to determine whether a drug increased
bone … We do not believe that this analysis should be
cited as evidence for increased risk. … risk of vertebral fracture as compared with those
whose BMD increased (Watts 2004). … -Increased odds with OR = 0.65? … The review cites an
increased relative risk of 1.27, citing an article, Bolland et al.,
2010 J.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/disparities-quality-improvement_executive.pdf
August 01, 2012 - .
• Within the HDZ zone, testing increased by 15% among Black
participants but not among White participants … • At 12 months, among intervention recipients, the baseline disparity
had increased from 6.7% to 7.7% … The intervention increased screening rates in both the private and
public insurance groups compared … The
patient navigator intervention was associated with increased
colorectal cancer screening among … In a few
instances, some increased effect is seen in disadvantaged
populations; these studies should
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-disease-medicine_executive.pdf
January 01, 2012 - Harms
•Screening or monitoring: false-positive
diagnosis or progression, anxiety,
unnecessary tests, increased … • Treatment with low-protein diet significantly increased risk of composite
outcome of mortality … medical visits, and increased difficulty
keeping health insurance coverage. … medical visits; increased
costs; difficulty keeping health insurance … medical visits; increased costs