-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain-2006_executive.pdf
January 01, 2006 - Osteoarthritis increases with age: the
incidence and prevalence increase two- to
tenfold from age 30 … to 65 and continue to
increase after age 65. … evaluated short-term use,
celecoxib caused fewer ulcer complications
than nonselective NSAIDs and did not increase … Adequate pain relief at the expense of an
increase in CV risk, for example, could be an
acceptable tradeoff … Others may
consider even a marginal increase in CV risk
unacceptable.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoporosis-bone-fracture_disposition-comments.pdf
March 01, 2012 - However, these studies did not
show an increase in mild cardiac events with raloxifene. … Vasodilation events are hot flashes, and raloxifene is known to
increase the risk of hot flashes. … These large trials also did
not detect an increase of mild cardiac events with raloxifene. … The finding of an increase in mild cardiac events associated
with raloxifene is incorrect and should … As opposed to the observational literature, we
did not find a statistically significant increase in
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-stones-draft-appendi-c.xlsx
January 01, 2024 - Increase in refined cereals (rice and pasta) to account for difference in animal protein HFD: Increase … fruits/vegetables and substitute usual cereals with whole grain products to achieve 25 g/d increase … (up to 0.8 mmol/day) Lemons and increased fiber intake
Magnesium deficiency: Increase in fiber intake … in area), 2-possible stone growth (10% to 50% increase in area), 3-no change in stone size (less than … in area), 2-possible stone growth (10% to 50% increase in area), 3-no change in stone size (less than
-
effectivehealthcare.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1412.pdf
October 01, 2015 - In the INPULSIS-2 trial, patients treated with nintedanib had a significant increase in time to
the … In an effort to increase the suitable donor lung supply, new
alternatives such as the use of lungs … The experts generally agreed that this
intervention has high potential to increase the quantity and … The experts generally agreed that this intervention has high potential to
increase the quantity and … Patient health outcomes could be improved by the purported increase in lung tissue
quality from the
-
effectivehealthcare.ahrq.gov/sites/default/files/crosscutting-horizon-scan-high-impact-1506.pdf
June 01, 2015 - to Aid Surgical Planning
Key Facts: Surgery performed on or near vital organs and structures can increase … Time dedicated to patient management may
increase when clinicians initially prescribe digital medicines … Ongoing data review and patient followup
may continue to increase the time clinicians spend on patient … Long-term cost
savings may be realized if digital medicines increase adherence enough to improve patient … Health disparities: Health disparities may increase for patients who do not have reliable access
to
-
effectivehealthcare.ahrq.gov/sites/default/files/ch_4-user-guide-to-ocer_130129.pdf
January 01, 2010 - In panel C, there is an increase in
the likelihood of the outcome with each exposure
that diminishes … Panel H shows a
linear increase in the risk/benefit associated with
exposure. … Continued
exposure to oral corticosteroids may continue to
increase the risk of fracture associated … scenario is panel I, which shows a large change
in risk/benefit upon initial exposure and then an
increase … For example, additional exposure to the vaccine
for mumps during childhood will not increase or
decrease
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/health-information-exchange_executive.pdf
December 01, 2015 - reductions
in radiology alone.9-11 A United States–based ambulatory
study found a reduced rate of increase … were mixed, with one study reporting fewer
consultations and cost savings7 and another reporting
an increase … care summaries,
and/or medication lists with an outside provider.2 This
represents an 85-percent increase … since 2008 and a
23-percent increase since 2013. … since 2008 and a
21-percent increase since 2013.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-2024-surv-rep-update-executive-sum.pdf
January 01, 2024 - There may be no increase in
risk of serious adverse events (SOE: low) or withdrawal due to adverse events … THC to CBD ratio) versus placebo,
updated meta-analyses changed pooled estimates for nausea (large increase … in risk) and
4
WAEs (moderate increase in risk) from nonstatistically significant
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-stone-prevention_executive.pdf
March 01, 2013 - multicomponent diet including high fiber57 with a
control diet suggested that a high-fiber diet may increase … participant
characteristics, including race, body morphometry, and
comorbid conditions that might increase … – Does low dietary calcium increase recurrent stone risk? … – Does low animal protein lower or increase recurrent stone
risk?
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-cholestorol-medicines-update_disposition-comments.pdf
September 01, 2014 - Table 1 on pg 32 of 411: what is meant by
“Limited” —is it a limited increase or decrease? … For example, the omega-3 FA Lovaza increases
LDL-C, while Vascepa does neither increase or
decrease … Second, what was reported
from ARBITER 6 (Taylor et al., 2009, ARBITER
6) was not a mean increase in … Increase in creatinine defines acute kidney
injury, independent of the eventual outcome. … One
would be very concerned that physicians
increase or add drugs when patients are not
adhering to
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/kidney-disease-medicine_research-protocol.pdf
November 01, 2010 - • Patient factors that may increase risk for CKD incidence, worsening or
complications, and that … - Patient factors that may increase risk for CKD incidence, worsening or
complications, and that … - Patient factors that may increase risk for CKD incidence, worsening or
complications, and that
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/rfviia.pptx
May 01, 2010 - Off-label, in-hospital rFVIIa use was estimated to be 125 cases in 2000, underwent a moderate increase … to 0.053) No effect* (●●○)
Medium (41-119 mg/kg)
29/399
(7.3) 13/378
(3.4) 0.035
(0.008 to 0.062) Increase … with
rFVIIa (●●○)
High (≥120 mg/kg)
8/115
(7.0) 0/107
(0) 0.063
(0.011 to 0.114) Increase with
rFVIIa … These results suggest that there is an increase in arterial thromboembolic events with rFVIIa use vs. … Overall Strength
of Evidence
Adult cardiac surgery 19/203
(9.4) 8/170
(4.7) 0.053
(0.01 to 0.096) Increase
-
effectivehealthcare.ahrq.gov/sites/default/files/rfviia.pptx
May 01, 2010 - Off-label, in-hospital rFVIIa use was estimated to be 125 cases in 2000, underwent a moderate increase … to 0.053) No effect* (●●○)
Medium (41-119 mg/kg)
29/399
(7.3) 13/378
(3.4) 0.035
(0.008 to 0.062) Increase … with
rFVIIa (●●○)
High (≥120 mg/kg)
8/115
(7.0) 0/107
(0) 0.063
(0.011 to 0.114) Increase with
rFVIIa … These results suggest that there is an increase in arterial thromboembolic events with rFVIIa use vs. … Overall Strength
of Evidence
Adult cardiac surgery 19/203
(9.4) 8/170
(4.7) 0.053
(0.01 to 0.096) Increase
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/preterm-birth-terbutaline-pump_surveillance.pdf
January 30, 2013 - Key Question 3: increase the maternal harms of arrhythmia, heart failure, hyperglycemia,
hypokalemia … Key Question 4: increase the neonatal terbutaline-related harms of hypoglycemia, hypocalcemia,
and ileus … Key Question 4: increase the neonatal terbutaline-related harms of hypoglycemia, hypocalcemia, and ileus … Key Question 3: increase the maternal harms of arrhythmia, heart failure, hyperglycemia, hypokalemia, … Key Question 4: increase the neonatal terbutaline-related harms of hypoglycemia, hypocalcemia, and ileus
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/preterm-birth-terbutaline-pump_surveillance.pdf
January 30, 2013 - Key Question 3: increase the maternal harms of arrhythmia, heart failure, hyperglycemia,
hypokalemia … Key Question 4: increase the neonatal terbutaline-related harms of hypoglycemia, hypocalcemia,
and ileus … Key Question 4: increase the neonatal terbutaline-related harms of hypoglycemia, hypocalcemia, and ileus … Key Question 3: increase the maternal harms of arrhythmia, heart failure, hyperglycemia, hypokalemia, … Key Question 4: increase the neonatal terbutaline-related harms of hypoglycemia, hypocalcemia, and ileus
-
effectivehealthcare.ahrq.gov/sites/default/files/05_depression_potential_high_impact_2012-12-10.pdf
January 01, 2012 - This
delay can increase suicide risk and mortality. … depressive episodes in patients with bipolar disorder or
MDD.
28,32
Ketamine has been shown to increase … That is, patient volume
in infusion centers might increase, which, in turn, would require increased … For these reasons, most experts believe, this intervention would increase
the per-patient cost of care … On one hand, if the
program is proven effective in increasing patient use of services, an increase
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-stone-prevention_disposition-comments.pdf
July 26, 2012 - It seems unlikely, however, that
reduction of soft drink consumption would
increase risk of mortality … Epidemiological data suggest
that low calcium diets increase risk of kidney
stones, and differences … stated in referring to the Borghi 2002 trial that
its findings suggested “low dietary calcium
may increase … asymptomatic stones may opt for
surgery if their stones show evidence of growth or if they have
an increase … placebo), the 95% confidence intervals
excluded a clinically significant increase in risk
of recurrence
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/copd-research-protocol.pdf
April 11, 2018 - corticosteroids have
historically only be used in stable COPD, but there is emerging evidence that an increase
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-evidence-communication_executive.pdf
November 01, 2013 - addresses the comparative effectiveness
of communicating evidence in various contents and
formats that increase … communicate evidence
so that target audiences can better understand it; the
strategies are meant to increase … many
settings (e.g., postal and electronic mail; electronic/
digital, social, and mass media) to increase … the reach of
information
• Increase motivation to use and apply such
information—Increasing interest … through champions (also known as “cheerleaders”),
opinion/thought leaders, or social networks
• Increase
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/quantitative-synthesis-expanded-methods_methods.pdf
March 01, 2013 - Summary
• Composite outcomes typically increase statistical efficiency. … Furthermore,
the proportion of event for each intervention group usually increases with the increase … of study
duration and the estimated RD may increase accordingly. … Alternatively, investigators could present results as a relative risk reduction or relative risk
increase … the combined RR was 1.36 (95% CI,
1.09–1.69).25 This finding could be expressed as a relative risk increase