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effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/white-paper-lung-cancer.pdf
August 01, 2021 - and Criteria in Solid Tumors)
Guideline1 definition of Progressive Disease (PD):
At least a 20% increase … In addition to the
relative increase of 20%, the sum must also demonstrate an
absolute increase of
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effectivehealthcare.ahrq.gov/sites/default/files/10_obesity_potential_high_impact_june_2012.pdf
January 01, 2012 - However,
experts opined that the increase in per-patient costs of care might serve as barriers to … treatment-discontinuation rate, and they were generally skeptical of whether treatment
might truly increase … However, potential increase in per-
patient costs might serve as barriers to acceptance by some patients … Patients were reported to have had a rapid increase and sustained insulin sensitivity,
increased levels … They were also generally skeptical about whether treatment would truly
increase the percentage of patients
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-IV-rapid-response-surgical-report-cards.pdf
November 01, 2023 - A surgical site infection (SSI) is estimated to
increase hospitalization costs by more than $20,000 … They created a data registry focused on adults with hernia disease with a
plan to gradually increase … Decrease in unadjusted SSI,
deep SSI, pneumonia, sepsis,
septic shock, LOS; increase
in CVA. … pre-op statin use
(58.87% to 71.81%;
p=0.0082), increase
discharge statin use (69.09%
to 80.37%; … p=0.0037);
increase pre-op antiplatelet
use (60.8% to 78.38%;
p<0.0001), and increased
discharge
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effectivehealthcare.ahrq.gov/sites/default/files/cer-229-opioid-treatments-chronic-pain-evidence-summary.pdf
April 01, 2020 - outcomes compared to no taper support, and co-
prescription of benzodiazepines and gabapentinoids
might increase … , prescription
of opioid medications for chronic pain
more than tripled from 1999 to 2015.2
This increase
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effectivehealthcare.ahrq.gov/sites/default/files/fagerlin-presentation.pdf
October 08, 2025 - It may increase their ability to figure out how much benefit they are
going to get from having chemotherapy … And
indeed
when
we showed
just two bars, we found
was a significant increase. … or ordinary events are
often
underestimated.
25
Peter Cram and his colleagues showed huge increase
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/patient-monitoring-systems-rapid-review.pdf
December 01, 2024 - Two studies reported a
statistically significant increase in transfers (p=0.00154 and p=0.0356), two … For cardiorespiratory arrest, two studies did not find positive
results.44, 50 One found a slight increase … For mortality, we found inconclusive evidence as
one study reported an increase and one a decrease, … Patient monitoring systems and early warning score and other interventions may
increase activations, … This, however, would be tempered if that same increase was
associated with significant decreases in
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-balancing-harms-benefits_research.pdf
February 01, 2014 - Results: The NNT and NNH for aspirin declined with increasing age because of the increase in
baseline … To
estimate the incidence rate we assumed a 50 percent increase from age category 65-74 years based … Both the NNT and NNH for aspirin consistently declined with
increasing age because of the increase in … At the same time, aspirin increased the number of major hemorrhagic strokes (35
percent RR increase, … Assumptions:
Applicability
RR reductions in benefits or RR increase in harms from the
trials were
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/nursing-staff-shortages-rapid-research.pdf
April 01, 2025 - satisfaction, medication errors, falls, hospital-
acquired pressure injuries, readmissions, and an increase … Segmentation did not require an
increase in physician staffing but
did require an increase in nurse … ) and non-designated hospitals (4.7% increase) but did not report whether
there was a statistically … in nursing time per
patient day, and a 9 percent increase in wage bill, or cost paid to non-physician … Does self-scheduling
increase nurses' job satisfaction? An
integrative literature review.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ced%20-appendix-2.xlsx
October 08, 2025 - Concern that increasing the number of requirements will increase burden on sponsors. … burdensome: We are concerned that expansion of the number of criteria from 13 to 19 marks a significant increase … burdensome: We are concerned that expansion of the number of criteria from 13 to 19 marks a significant increase … during public comment period is not suffcient Concern that increasing the number of requirements will increase
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoarthritis-pain_research-protocol.pdf
August 05, 2010 - symptomatic osteoarthritis of
the hip.3 Osteoarthritis increases with age: the incidence and prevalence increase … two-
to tenfold from age 30 to 65 and continue to increase after age 65.4 The total costs for
arthritis … • All non-aspirin NSAIDs work equally well for pain reduction
• NSAIDs increase the risk of GI bleeding … • Celecoxib, high dose ibuprofen, and high dose diclofenac increase the risk of
myocardial infarction … Naproxen does not increase the risk of myocardial infarction.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/carbohydrate-intake-executive-summary.pdf
May 01, 2025 - Low carbohydrate diets may increase
risk of neural tube defects. … Complementary Foods
Based on Nordic Ingredients Combined with
Systematic Introduction of Taste Portions
Increase
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/antibiotics-respiratory-infection_executive.pdf
January 01, 2016 - The evidence for this type of intervention shows reduction
in inappropriate or increase in appropriate … The evidence also
indicates an increase in reconsultations within 4 weeks
(N = 3 RCTs) but no effect … Together, we found this to be low-strength evidence of a
potential increase in risk of hospitalization … Studies were not combinable; therefore, this evidence was
low strength for a small absolute increase … The combined OR for
hospitalization was 2.17 (95% CI, 0.85 to 5.50), indicating
a potential increase
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/gaps-pain-management.pdf
January 01, 2023 - nonsteroidal anti-inflammatory
drugs), dihydroergotamine, antiemetics, and
acetaminophen, reduce pain but increase … antagonists and lasmiditan (5-
HT1F receptor agonist) probably improve pain
relief at 2 hours and increase … Study Design
• Systematic reviews and trials that increase
followup time and pain assessment beyond
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-IV-surgical-report-cards.pdf
July 01, 2023 - hospital settings and ambulatory care centers.6 Postoperative complications occur
frequently and can increase … report cards focused on any intervention
that is specifically designed to promote patient safety, increase … strategies to
focus on finding the most valuable studies (i.e., being flexible on sensitivity to increase
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/echocardiography_research.pdf
May 01, 2014 - This increase occurred at
a higher rate than non-cardiac imaging services, and was greater
than might … in the
late 2000s, but it remains an often used procedure.7,8
Efforts have been made to slow the increase … echocardiography in primary care offices
has been hypothesized to be a possible
driver of this increase … There was a small increase in the
percentage of beneficiaries receiving four
and five or more services … Do imaging studies performed in physician offices increase
downstream utilization?
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoporosis-vibration-therapy_research-protocol.pdf
January 01, 2020 - dietary and pharmacological interventions to treat osteoporosis and prevent
bone fractures.5-9 An increase … osteonecrosis of the jaw.11-15 Alternative therapies, including
weight-bearing exercise, may also increase … circulation, increasing the
supply of nutrients needed to build bones.20,41-44
Using vibration therapy to increase
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effectivehealthcare.ahrq.gov/sites/default/files/12_pregnancy_potential_high_impact_june_2012.pdf
January 01, 2012 - trisomies
ES-6
has potential to disrupt diagnostic paradigms and care delivery methods and increase … This provides a great opportunity to
harness this technology to increase the reach of attempts to close … On one hand, costs could increase because more patients might seek more prenatal care. … Many experts
believe while there may be an initial increase in costs, the reduction in costs stemming … Experts agreed while initial per-patient costs may increase, reducing long-term health
complications
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-research-report-integrating-health-system-data.pdf
April 01, 2020 - unpublished data, primarily because the published
data was sparse or lacked granularity (i.e., to increase … /or to determine whether the published data were applicable to health
system populations (i.e., to increase … included a call to research,
explicitly asking health systems to rigorously evaluate their efforts to increase … Based on selected
examples, demonstrating concordance can increase the certainty for decision makers … Research Lifecycle to Increase the
Substantial Real-World Impact of Research:
Accelerating Innovations
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-update_surveillance.pdf
December 31, 2013 - Increase in overall mortality risk
28 … A week 80 decrease of 3.37 kg in the metformin group and
an increase of 1.42 kg in the Avandamet group … Increase in total cholesterol in the Avandamet group with little change in
LDL cholesterol. … HDL-C increased with both treatments, with
pioglitazone treatment resulting in a greater increase. … Non-dose-dependent increase in symptomatic
genital infections with canagliflozin (3-8%) versus placebo
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/research-gap-primary-care-summary-table.pdf
March 01, 2022 - antagonists and lasmiditan (5-
HT1F receptor agonist) probably improve pain relief
at 2 hours and increase … Study Design
• Systematic reviews and trials that increase followup
time and pain assessment beyond … • Antibiotics and corticosteroids are not associated
with increase in serious adverse events. … • Long-term bisphosphonates may increase atypical
femoral fractures and osteonecrosis of the jaw, … • Long-term oral hormone therapies reduce hip and
clinical fractures but increase multiple serious