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  1. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0174_10-20-2009.pdf
    January 01, 2009 - The scope of this topic, including populations, interventions, comparators, and outcomes, will be further … Intervention(s): Physical and rehabilitative therapy (excluding pharmacotherapy and operative procedures) including … devices Comparator(s): See above interventions and no treatment Outcome(s): Intermediate outcomes including … pain, swelling, inflammation, strength, flexibility, range of motion; and patient-centered outcomes including
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0261_07-16-2010.pdf
    January 01, 2010 - The scope of this topic, including populations, interventions, comparators, and outcomes, will be further … diagnosed with asthma Intervention(s): Interventions to improve guideline implementation and adherence, including … above Outcome(s): Guideline implementation and adherence; outcomes of improved guideline adherence, including … plans and self-management education who are classified by stage and risk; effects on patient outcomes including
  3. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0272_03-06-2008.pdf
    January 01, 2008 - The scope of this topic, including populations, interventions, comparators, and outcomes, will be further … In addition, one nominator expressed interest in patients with comorbidities (including pulmonary hypertension … What other modalities of treatment, including weight loss, surgery, and oral appliances, would be better … What is the evidence to support alternate treatment modalities including CPAP, surgery, and oral appliances
  4. effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/research-gap-primary-care-summary-table.pdf
    March 01, 2022 - ) • Exploration of effects of different cannabinoids, and/or other plant-based products, including … • Longitudinal studies on opioids to evaluate longer- term outcomes, including associated harms ( … Evidence Gaps Study Populations • Studies that examine subpopulations including older adults and … • Longitudinal outcome studies on opioids, including harms (e.g., refractory opioid dependence, … • Evidence is low or insufficient for effects of population barriers, including insurance, access
  5. effectivehealthcare.ahrq.gov/sites/default/files/pdf/tonsillectomy_research-protocol.pdf
    February 10, 2016 - Choice  of   technique  may  depend  on  factors  including  the  underlying  indication  for  surgery …   harms,  of  tonsillectomy  compared  with  watchful  waiting  with  supportive  care  (including   … **Includes  breathing  difficulties  during  sleep  as  operationalized  in  each  study,  including   … We  will  require  that  studies  including  mixed     Source: www.effectivehealthcare.ahrq.gov …  study  design,  year,  setting   •   Population  characteristics  including  age,  race,  ethnicity
  6. effectivehealthcare.ahrq.gov/sites/default/files/pdf/urinary-incontinence-update_research-protocol.pdf
    June 06, 2017 - Treatment Outcomes The 2012 AHRQ review evaluated a wide range of patient outcomes, including objective … Evidence Gaps from the Prior Review The 2012 AHRQ review found several research gaps, including: 1) … Which patient characteristics, including age, type of UI, severity of UI, baseline diseases that affect … Which patient characteristics, including age, type of UI, severity of UI, baseline diseases that affect … * Health education about UI; behavioral therapy, including “lifestyle” interventions (e.g., dietary
  7. effectivehealthcare.ahrq.gov/sites/default/files/related_files/musculoskeletal-complaints-tests-children_surveillance.pdf
    January 08, 2013 - A new case control study including 50 healthy children7 found 8% RF positive and 2% CCP positive. … Key Question 3.1 ANA Test for pSLE in Children With MSK Pain Two case-control studies including 201 … ANA Test for JIA in Children With MSK Pain Eight case-control studies including 1,382 children (1,067 … CCP Test for JIA in Children With MSK Pain Seven case-control studies including 1,643 participants … CCP Test for JIA in Children With MSK Pain Seven case-control studies including 1,643 participants
  8. effectivehealthcare.ahrq.gov/sites/default/files/pdf/pressure-ulcer-treatment_research-protocol.pdf
    November 08, 2011 - nutritional supplementation. 1,4 In addition, various adjunctive therapies have been evaluated, including … Question 2b Do the harms of treatment strategies differ according to patient characteristics, including … Grey literature— including unpublished data, abstracts, dissertations, and individual product packets … home, nursing facility, and hospital; and features of the patient care setting including nurse/patient … The results will be presented in tables to outline the key outcomes including complete wound healing
  9. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0251_05-20-2010.pdf
    January 01, 2010 - The scope of this topic, including populations, interventions, comparators, and outcomes, will be further … debridement, semipermeable dressings, topical applications, hyperbaric oxygen, and surgical flaps) including … treatment teams and protocols; and various prevention strategies including specialized mattresses, … What are the benefits and harms of pressure ulcer treatment regimens including the evidence for treatment
  10. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0519_02-27-2012.pdf
    January 01, 2012 - The scope of this topic, including populations, interventions, comparators, and outcomes, will be further … Staff-Generated PICO Population(s): Patients with heart failure requiring hospitalization, including … severity, and ejection fraction status Intervention(s): Interventions to decrease hospital readmissions, including … Cardiomyopathy Questionnaire or Minnesota Living with Heart Failure Questionnaire, and patient-related harms including
  11. effectivehealthcare.ahrq.gov/sites/default/files/cer-239-acute-migraine-evidence-summary.pdf
    December 01, 2020 - several other therapies available in the United States may improve migraine pain compared with placebo, including … Background and Purpose In patients with migraine, several acute treatment options are available, including … systematic review assesses the comparative effectiveness and harms for acute migraine treatments, including … • Antiemetics, including prochlorperazine, chlorpromazine, metoclopramide, droperidol and haloperidol … one or a few small trials, several other therapies may improve migraine pain compared with placebo, including
  12. effectivehealthcare.ahrq.gov/sites/default/files/related_files/ehc-research-gaps-telehealth.pdf
    April 01, 2023 - impact of telehealth care within alternative payment arrangements (e.g., risk-based arrangements), including … • Use of telehealth for provider education/mentoring, including programs like Extension for Community … • Studies that consider the larger policy context in which care was delivered, including payment … • A stakeholder panel including a wide range of providers, policymakers, and, importantly, patients … • Studies, including multisite trials, that facilitate collecting economic data alongside trials
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/long-covid-protocol.pdf
    February 18, 2023 - cardio-pulmonary symptoms; anosmia and dysgeusia; headache; gastrointestinal symptoms; and dysautonomia (including … What are potential facilitators and barriers to implementation, including resources needed, and how … Details on model of care, including the types of interventions used and specifics of pharmacological … We will select Key Informants to ensure appropriate multidisciplinary representation, including persons … In order to ensure that we are including studies of long COVID models of care that may be published
  14. effectivehealthcare.ahrq.gov/sites/default/files/related_files/hnhc-disposition-comments.pdf
    October 29, 2021 - We expanded our presentation of the framework synthesis approach, including adding a figure of the … We added information describing the KQ1 qualitative studies, including a summary table and that we … the connection between our three review approaches to form a more cohesive story across the review, including … We added to the recommendations section, further highlighting key takeaway findings, including adding … o We corrected several minor spacing and copyediting errors, including pluralization errors, a spelling
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/saturated-fat-replacement-protocol.pdf
    January 01, 2024 - o Dyslipidemia (including if taking lipid lowering medications) o Overweight/obese o Hyperglycemia … and related conditions, including type 2 diabetes o Hypertension/high blood pressure Key Question … different types (complex including fiber, refined, sugars) o Protein o Unsaturated fatty acids … Additional articles suggested to us from any source, including peer and public review, will be screened … Within each section, we will organize findings by life stage and sex, including highlighting groups
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/breastfeeding-health-outcomes-protocol-amendment.pdf
    February 03, 2025 - long-term benefits for children and mothers has led multiple national and international organizations, including … with their counterparts.9-12 These groups disproportionately face several barriers to breastfeeding, including … How do these associations vary by intensity (including exclusivity), duration, and mode of feeding, … Additional articles suggested to us from any source, including peer and public review, will be screened … criteria and will note the analytic approach used, including any attempts to explore heterogeneity.
  17. effectivehealthcare.ahrq.gov/sites/default/files/related_files/effect-protein-intake-executive-summary.pdf
    November 01, 2024 - • To assess chronic disease risk, studies used intermediate markers, including surrogate markers … bone disease, kidney disease, and sarcopenia risks, aiming to inform updates to the protein DRIs, including … Strengths and Limitations Our systematic review had several strengths, including a unique emphasis on … only on studies rated low to moderate risk of bias, we limited the size of our body of evidence, but including … Our review identifies evidence base limitations, including reliance on recognized intermediate markers
  18. effectivehealthcare.ahrq.gov/sites/default/files/pdf/cerebral-palsy-feeding_research-protocol.pdf
    June 12, 2012 - • Paraplegia/paraparesis means the lower half of the body, including both legs, are affected. … Multiple approaches may be used in children with growth failure, including sensorimotor stimulation, … Limited information is available on the impact on long-term health outcomes, including quality of life … We anticipate adapting or including (with appropriate permissions) relevant results tables from prior … Reporting bias Are the potential outcomes, including harms, pre-specified by the researchers?
  19. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0263_12-28-2007.pdf
    January 01, 2007 - The scope of this topic, including populations, interventions, comparators, and outcomes, will be further … of adding recombinant human growth hormone (rhGH) to usual care for patients with cystic fibrosis, including … What is the effectiveness of rhGH for CF patients for improving clinical outcomes including: height
  20. effectivehealthcare.ahrq.gov/sites/default/files/pdf/progestogens-preterm-birth_research-protocol.pdf
    June 01, 2010 - However, we will be capturing information on important health services data, including costs and any … Comparators Placebo, usual care (not including a progestogen), and other interventions to prevent … preterm birth and its consequences, including antibiotics; corticosteroids; tocolysis; bedrest; dietary … Outcomes for each Key Question Fetal/neonatal outcomes: • Gestational age at birth, including preterm … We will begin with a search on topics that include various entries including, but not limited to, “

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