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Total Results: 2,624 records

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441. Hepatitis-C-Treatment-Adherence Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c-treatment-adherence_executive.pdf
     September 22, 2011 - Studies have shown that a variety of factors affect treatment response, including viral or disease-related … A good-quality retrospective cohort study including 1,560 patients32 used propensity scoring methods … We encountered additional issues in crosstrial comparisons for these studies, including studies that … There was no evidence regarding health outcomes, including harms related to patient-level adherence … These studies recruited patients from various clinical settings, including primary care, specialized

442. head-neck-cancer-update-140204 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/head-neck-cancer-update_research-protocol.pdf
     February 04, 2014 - Several grading instruments have been created to assess these, including the National Cancer Institute … The data elements to be abstracted will include the following: • Patient characteristics, including: … Additional (optional) domains including strength of association (magnitude of effect), dose-response … Assessment of reporting bias for individual studies depends on many factors including availability … In the EPC grading system, a body of evidence including RCTs is assigned a provisional SOE grade of

443. Title (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/mental-illness-adults-prisons_research-protocol.pdf
     September 13, 2012 - It combines several treatment models, including CBT, illness management, supported housing, IDDT, and … Case management interventions, including, but not limited to: Strengths-based case management. … ACT provides comprehensive (around-the-clock) community care to patients who are mentally ill, including … Studies must have an active treatment comparator (including treatment as usual). … The Cochrane Library (including the Central Register of Controlled Trials, the Cochrane Database of

444. Ch 6-User-Guide-To-Ocer 130129 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/ch_6-user-guide-to-ocer_130129.pdf
     October 30, 2012 - It is measured by statistics including kappa, and the inter- or intra-class correlation coefficient … Patients can also report about their health behaviors, including adherence and health habits. … Another questionnaire, the SF- 36, measures eight domains including general health perceptions, pain … For PROs, measurement error can stem from several sources, including the way in which a question is … In other cases, redesigning items and scales, for example, by including both positively and negatively

445. Treatment of Osteoarthritis of the Knee: An Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoarthritis-knee-update_research-protocol.pdf
     June 15, 2016 - The clinical diagnosis of OA of the knee is typically based on presentation, including insidious onset … Numerous recent evidence-based treatment guidelines have been issued, including the 2012 American College … However, one commenter suggested including only studies that reported patient specific outcomes. … the other included interventions (including a 2012 EPC review on the use of physical modalities to … AAOS: not mentioned Indicated for treatment of chronic musculoskeletal pain including discomfort

446. Urinary-Incontinence-Treatment Surveillance (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/urinary-incontinence-treatment_surveillance.pdf
     October 29, 2012 - What are the diagnostic values of the methods listed above for different types of UI, including stress … Which patient characteristics, including age, type of UI, severity of UI, baseline disease that affects … Which patient characteristics, including age, type of UI, severity of UI, baseline disease that affects … What are the diagnostic values of the methods listed above for different types of UI, including stress … Which patient characteristics, including age, type of UI, severity of UI, baseline disease that affects

447. Disposition of Comments for Screening for Glaucoma: Comparative Effectiveness (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/glaucoma-screening_disposition-comments.pdf
     April 01, 2012 - The AHRQ review focuses on the technical aspects of glaucoma screening, including the area under the … the United States We included studies of all settings in which screening could potentially occur including … The aim of Key Question 2 was to capture patient reported outcomes including quality of life and patient … The study found lower vision-related QOL in those with glaucoma, including those previously unaware … Including participants who are not representative of those one reasonably expects to encounter in a

448. Trauma-Child-Interventions Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/trauma-child-interventions_executive.pdf
     February 01, 2013 - terms of psychological and social functioning, some go on to develop traumatic stress syndromes, including … KQ 4 illustrates the harms associated with specific interventions, including retraumatization, side … substance use), behavioral problems (including conduct disorder and ADHD), or criminal activities … • Healthy development (including improvements in interpersonal and social functioning), or reductions … substance use), behavioral problems (including conduct disorder and ADHD), or criminal activities

449. depression-pregnancy-postpartum-protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/depression-pregnancy-postpartum_research-protocol.pdf
     March 29, 2013 - adverse obstetric complications have been reported with untreated prenatal stress and depression, including … of nonpharmacological interventions that can be used to treat depression in the postpartum period including … Additional outcomes were suggested by the TEP, including infant attachment and child interaction with … • Maternal health system resource utilization including emergency department use, hospitalizations … Harms Maternal • Death (including suicide, all-cause mortality and cause-specific [e.g., cardiac]

450. Arthritis-Psoriatric Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/arthritis-psoriatric_executive.pdf
     April 01, 2012 - , very little is known about the benefits or risks of these drugs in different patient subgroups, including … the Center for Drug Evaluation and Research (CDER) database of the FDA and unpublished literature, including … Table B gives a range for effect sizes for commonly reported measures, including the American College … For the oral DMARDs, including sulfasalazine and methotrexate, sparse data are available. 6 Table … For the oral DMARDs, including sulfasalazine and methotrexate, the sparse data available involved placebo

451. Urinary-Incontinence-Treatment Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/urinary-incontinence-treatment_executive.pdf
     April 01, 2012 - What are the diagnostic values of the methods listed above for different types of UI, including stress … For each study, we examined settings, including ambulatory care or specialized clinics, recruitment … We assessed missing data across studies, including loss to followup and dropout patterns, and forced … • Treatment benefits, including continence, were achieved with antimuscarinic drugs, including trospium … • Pharmacological treatments for stress UI, including off-label use of low-dose topical estrogen

452. Peripheral-Artery-Disease-Treatment Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/peripheral-artery-disease-treatment_research-protocol.pdf
     January 31, 2013 - prevalence of PAD increases with age, such that roughly 20 percent of patients over age 65 have PAD (including … KQ 1: In adults with peripheral artery disease (PAD), including asymptomatic patients and symptomatic … The safety outcomes will be framed to help identify adverse events, including adverse drug reactions … These studies adhered to the commonly held concepts of high quality, including the following: a clear … The Task Order Officer reviewed contract deliverables for adherence to contract requirements, including

453. Hepatitis-C Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c_executive.pdf
     November 01, 2012 - Do these harms differ according to patient subgroup characteristics, including HCV genotype, age, race … Final outcomes were morbidity and mortality from HCV infection (including hepatic cirrhosis, HCC, and … liver transplantation rates) and quality of life, as well as harms of antiviral therapies (including … We performed sensitivity analysis by excluding poor-quality studies and outlier trials, and by including … However, the studies had methodological shortcomings, including inadequate handling of confounders,

454. Effectiveness and Safety of Bronchial Thermoplasty in Management of Asthma: Evidence Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/evidence-summary-cer-202-bronchial-thermoplasty-asthma.pdf
     December 01, 2017 - Results Fifteen studies, including three randomized controlled trials (RCTs) with 5-year single-arm … patients are potential candidates for BT may want to consider the evidence presented in this review, including … and heterogeneous study populations, limited improvement in outcomes, and rates of adverse events (including

455. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/dementia-nursing-home-characteristics_research-protocol.pdf
     November 03, 2011 - A person must meet several eligibility criteria, including low income, to qualify for payment. … These may include aspects of staffing, including the following: stability of care provider-resident … The public comments suggested including specific examples of processes of care and outcomes. … be provided in many settings, including private homes, our evidence- based review will be limited to … We will design data abstraction forms to gather pertinent information from each article, including

456. Integrating Bodies of Evidence: Existing Systematic Reviews and Primary Studies (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/integrating-evidence_methods.pdf
     February 01, 2015 - principles for integrating primary (study-level) and secondary (systematic review-level) evidence, (including … Several factors can be considered in assessing relevance, including the date(s) of the search (currency … with reasons for exclusion is ideal but it may not be reasonable to exclude a prior review for not including … Qualitative and Quantitative Synthesis One rationale often used for including existing systematic reviews … • Further work around decisions about synthesis including: o A methods study to empirically test

457. antibiotics-respiratory-infection-protocol-140922 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/antibiotics-respiratory-infection_research-protocol.pdf
     September 22, 2014 - These outcomes have a weak link to health outcomes, including antibiotic resistance than other intermediate … Topic refinement was undertaken by the Pacific Northwest Evidence-based Practice Center (PNW EPC), including … versus inappropriate use of antibiotics in Acute RTI will be recorded as reported in each study, including … *Including adults, children, or the parents of children with acute RTI. IV. … In addition to Edited to give more explanation of the types of interventions, including more

458. Future Research Needs for Treatment of Obstructive Sleep Apnea (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/sleep-apnea-treatment-future_research.pdf
     February 01, 2012 - A variety of interventions should be considered, including but not limited to fixed and alternative … Several possible solutions exist for these problems; including reducing the number of stakeholders; … Various approaches to improve participation and discussion are possible, including increased use of … Not including comments or questions added by the EPC, for the 30 topics discussed online, the median … Addresses inequities, vulnerable populations (including issues for patient subgroups) 4f.

459. Systematic Review of Intermittent Inhaled Corticosteroids and of Long-acting Muscarinic Antagonists for Asthma (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-pharmacologic-treatment_research-protocol.pdf
     December 27, 2016 - • KQ2b: ICS+another controller therapy, including LABA, leukotriene modifiers, cromolyn, methylxanthines … All studies, including those that are not amenable to pooling, will be qualitatively summarized. … Key Informants Key Informants are the end users of research, including patients and caregivers, practicing … term, once-daily maintenance bronchodilator treatment of airflow obstruction in patients with COPD, including … evening) administration in the maintenance treatment of bronchoconstriction in patients with COPD, including

460. A Framework for Conceptualizing Evidence Needs of Health Systems (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/white-paper-framework-for-conceptualizing-evidence-needs_0.pdf
     December 01, 2017 - This work is one of several complementary AHRQ projects about Learning Health Systems, including AHRQ … The studies show that health systems’ questions can be asked at various levels, including the level … After using several data sources including published literature, original data from evidence synthesis … Other authors have provided similar arguments suggesting that a broad definition of evidence including … Participants preferred tables including study event rates and absolute differences Wye 201535 UK