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401. Masks-Surveillance-2-Appendix-Table-A-2 (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/masks-surveillance-2-appendix-table-a-2.xlsx
     March 01, 2020 - for household with secondary infection of family member Mask use all the time by all family members (including … members vs. no family members: 0.72 (0.30 to 1.73) Mask use all the time by at least one family member (including

402. Kidney-Stone-Prevention Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-stone-prevention_executive.pdf
     March 01, 2013 - • We found no evidence regarding whether diets including increased calcium, low sodium, low oxalate … However, in one trial, a multicomponent diet including normal to high dietary calcium had significantly … By comparison, two trials that compared a high-fiber diet56 or a multicomponent diet including high … They otherwise reported almost no data on the prevalence of participant characteristics, including … • RCTs should collect and completely report predefined adverse events including effects on comorbid

403. Abnormal-Uterine-Bleeding Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/abnormal-uterine-bleeding_research-protocol.pdf
     November 21, 2011 - in those ages 36 to 40 years. 1, 2 In addition to gynecologists, all primary care practitioners including … indefinitely continue medical therapy. 2, 21 Current recommendations from professional societies including … Key Question 2: What are the harms, including adverse events, associated with medical, behavioral, … Several factors, including varying prevalence of cyclic and irregular patterns of abnormal uterine … Key Informants Key Informants are the end users of research, including patients and caregivers,

404. Treatment for Restless Legs Syndrome Disposition of Comments Report (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/restless-legs_disposition-comments.pdf
     November 27, 2012 - Public Comment Methods Consider including additional endpoints of assessment, as many studies with … We included studies reporting on a wide range of study outcomes including change in IRLS total scores … Most studies, including the best study (REST) report around a 10% prevalence in Caucasian populations … We respectfully request AHRQ to reconsider including these outcomes of SP709 as appropriately applied … We respectfully request AHRQ to reconsider including these outcomes in this review.

405. Management of Suspected Opioid Overdose With Naloxone by Emergency Medical Services Personnel - Executive Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-193-naloxone-executive-summary.pdf
     November 01, 2017 - or suspected opioid overdose in out-of-hospital settings treated with multiple doses of naloxone (including … or suspected opioid overdose in out-of-hospital settings treated with multiple doses of naloxone (including … Studies should evaluate benefits as well as important harms, including withdrawal, agitation, aspiration … Importantly, observational studies should be designed to reduce risk of confounding and bias, including … either of these questions, the protocols used for naloxone dosing will need to be clearly defined, including

406. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/stroke-atrial-fibrillation_research-protocol.pdf
     January 30, 2012 - acute coronary syndrome o Subpopulations, including: patients with comorbid conditions, such as … • Patients who have known reversible causes of AF (including but not limited to postoperative AF … We will use several approaches to identify relevant gray literature, including requests to drug and … The safety outcomes will be framed to help identify adverse events, including those from drug therapies … These studies adhered to the commonly held concepts of high quality, including the following: a clear

407. Stakeholder Involvement in Improving Comparative Effectiveness Reviews: AHRQ and the Effective Health Care Program (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/stakeholder-engagement_research.pdf
     September 01, 2011 - Program Product Development Workgroup provided regarding several key programmatic and content areas, including … to ensure that its CERs and other evidence reviews are useful to a broad range of decisionmakers, including … Process The Product Development Work Group met 12 times between January 2008 and February 2010, including … Results Members provided specific input regarding several key programmatic and content areas, including … by clinical evidence.9 Various payers define alternative criteria for the medical necessity of PBT including

408. chronic-fatigue-protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-fatigue_research-protocol.pdf
     May 01, 2014 - attempt to describe the condition based on the proposed etiologies, several other terms have been used, including … The syndrome that encompasses ME/CFS is characterized by various manifestations of diffuse symptoms including … Controversies surrounding ME/CFS have led to wide variations in the clinical management of patients, including … Each full-text article will be independently reviewed for eligibility by two team members, including … consider the quality of the studies and the heterogeneity among studies in design, patient population including

409. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/type-2-diabetes-medications-update_research-protocol.pdf
     April 06, 2010 - These studies adhered to the commonly held concepts of high quality, including the following: a formal … Summary of Protocol Amendments 04-02-2010 Amendment I Including Drugs Recently Approved by the … We are also considering including comparisons between metformin and combinations of metformin with TZDs … We are considering including head-to-head comparisons of the following combinations: • Metformin and … We are tallying, but not including, studies that compare the metformin combinations mentioned above

410. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/depression-brain-injury_research-protocol.pdf
     December 09, 2009 - or difficulty concentrating.2 TBIs are associated with a range of short- and long-term sequelae, including … high rates of depression (up to more than half of cases) and of other axis I and axis II conditions, including … Furthermore, depression was noted to be comorbid with other psychiatric conditions, including addiction … What are the outcomes (short and long term, including harm) of treatment for depression amongst traumatic … We will begin with a search on topic that include various entries including but not limited to “traumatic

411. Infantile-Hemangioma Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/infantile-hemangioma_executive.pdf
     January 01, 2016 - classifies IH as vascular tumors that are differentiated from vascular malformations in several ways including … IH is diagnosed and treated by clinicians including pediatricians, dermatologists, otolaryngologists … Relative to other modalities, including steroids and bleomycin, we find that propranolol is generally … In studies comparing propranolol with other active comparators including steroids, PDL, bleomycin, or … Most comparative studies evaluated laser treatments including short-pulse and longer pulse PDL, Nd:

412. The Effectiveness and Risks of Long-Term Opioid Treatment of Chronic Pain (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-pain-opioid-treatment_executive.pdf
     September 19, 2014 - accumulating evidence indicates that prescription opioids may be associated with important harms, including … opioid on: (1) opioid abuse, addiction, and related outcomes; (2) overdose; and (3) other harms, including … pain prescribed long-term opioid therapy, what is the effectiveness of risk mitigation strategies, including … *Including opioid management plans, patient education, urine drug screening, use of prescription drug … No studies examined how effectiveness varies based on various factors, including type of pain and patient

413. Template for Draft Reports (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/long-term-care-adults-future_research.pdf
     July 01, 2013 - We engaged consumer and provider groups, including AARP and the National Center for Assisted Living … There was insufficient evidence for most outcomes examined in the CER, including outcomes related to … We sought recommendations from the CER project team, including select Key Informants and Technical … We engaged consumer and provider groups, including AARP and the National Center for Assisted Living … To facilitate this input, we provided stakeholders in advance with background material including

414. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/patient-safety-practices_research-protocol.pdf
     November 09, 2011 - postulated, and in some cases shown, to influence the effectiveness of a patient safety practice, including … Describe the patient safety practice in sufficient detail that it can be replicated, including the … Assess the effect of the patient safety practice on outcomes and possible unexpected effects, including … will take into consideration a number of domains relevant to both internal and external validity, including

415. Psychosocial and Pharmacologic Interventions for Disruptive Behavior Disorders in Children and Adolescents: Current State of the Evidence (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/disruptive-behavior-disorder_clinician.pdf
     August 01, 2016 - Psychosocial interventions, including but not limited to psychotherapy, have been developed for some … A wide range of psychotropic medications—including anticonvulsants, antipsychotics, mood stabilizers … to refer to harms data from other sources that might include more extensive and longer term data, including … and Caregivers of Children with DBDs �� What DBDs are �� The potential long-term risks of DBDs, including

416. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/vte-prophyalaxis_research-protocol.pdf
     March 01, 2011 - Populations at Risk for Venous Thromboembolism The burden of VTE is higher among special populations including … Obesity, including severe obesity, is associated with an increased risk of VTE. 41 It is uncertain … pharmacologic agents used to treat patients at the extremes of weight, the optimal dosing strategy (including … These studies adhered to the commonly held concepts of high quality, including the following: a clear … meta-analyses, we will conduct formal tests for publication bias by using Begg’s and Egger’s tests, including

417. Evidence Report on the (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/dietary-supplements_research-protocol.pdf
     December 15, 2010 - heart failure or other cardiovascular disease use some form of CAM.8,10 Dietary supplementation, including … Grey literature will be identified through a search of trial registries (including ClinicalTrials.gov … Data—including baseline value, final value, within-treatment change or between-treatment difference, … Including studies in languages other than English is recommended for CAM topics.1,2 However, there is … Review authors may want to search without language restrictions and decisions about including reports

418. 8 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-harms_methods.pdf
     November 01, 2008 - Use multiple sources of information, including clinical experts and stakeholders, to identify important … Gather evidence on harms from a broad range of sources, including observational studies, particularly … In addition to evaluating results of published RCTs, CER authors should consider including results … To conduct formal quantitative meta-analysis, including published and unpublished RCTs or outcomes. … However, CERs should match inclusion criteria to the reasons for including observational studies.

419. 8 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/methodsguide_chou_assessing_harms_when_comparing.pdf
     November 01, 2008 - Use multiple sources of information, including clinical experts and stakeholders, to identify important … Gather evidence on harms from a broad range of sources, including observational studies, particularly … In addition to evaluating results of published RCTs, CER authors should consider including results … To conduct formal quantitative meta-analysis, including published and unpublished RCTs or outcomes. … However, CERs should match inclusion criteria to the reasons for including observational studies.

420. Binge-Eating Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/binge-eating_research-protocol.pdf
     July 21, 2014 - LOC eating has detrimental psychological and physical health effects,4-6 including significant distress … ) and symptoms often endure well beyond midlife,16,17 with the general course of illness sometimes including … The APA recommends CBT incorporated into a team approach including psychiatrists, psychologists, dietitians … Including bariatric surgery patients as a separate population in the review is timely and needed. … Senior members of the review team (including at least one subject matter expert and one methodologist