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2461. #06 Developmental Delays ADHD, and Autism (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/developmental-delays-horizon-scan-high-impact-1406.pdf
      June 01, 2014 - this intervention did not consider it to have high- impact potential at this time, citing factors including … spray formulations are also available without prescription on the Internet from various companies, including … for these products has not been made publicly available.41,42 Several academic medical centers—including … However, no approved medications are available that effectively treat ASD core symptoms, including … Intranasal oxytocin is expected to be used as an adjunct to present interventions, including behavior

2462. AHRQ Slide Template 2004 (ppt file)
      effectivehealthcare.ahrq.gov/sites/default/files/introduction.ppt
      January 01, 2010 - CE research focuses on improving health outcomes that are important to health care decisionmakers, including … The EHC Program provides opportunities for public input at various stages of research, including at the … Stakeholders, including researchers and funders, may help develop and prioritize the research gaps. … to help answer key questions and to ensure that these identified needs are useful to stakeholders, including … to fill the evidence gaps, the Evidence-based Practice Centers will need to work with stakeholders, including

2463. AHRQ Slide Template 2004 (ppt file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/introduction.ppt
      January 01, 2010 - CE research focuses on improving health outcomes that are important to health care decisionmakers, including … The EHC Program provides opportunities for public input at various stages of research, including at the … Stakeholders, including researchers and funders, may help develop and prioritize the research gaps. … to help answer key questions and to ensure that these identified needs are useful to stakeholders, including … to fill the evidence gaps, the Evidence-based Practice Centers will need to work with stakeholders, including

2464. Autism-Adolescents Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/autism-adolescents_executive.pdf
      August 01, 2012 - special emphasis on translating findings into a variety of useful formats for different stakeholders, including … similarly aged adolescents without an ASD; other care costs were also higher in this population, including … Treatment choices may target intermediate outcomes including changes in communication skills, academic … (RCTs), one fair quality21 and two poor,20,40 addressed the efficacy of antipsychotic medications including … As in the case of efficacy, the data on adverse effects associated with risperidone, including sedation

2465. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/trauma-interventions-maltreatment-child_research-protocol.pdf
      January 12, 2012 - Activation of the HPA axis releases a cascade of steroid hormones, including the primary stress hormone … Dysregulation of the HPA axis also affects key regions of the brain, including the areas responsible …  Psychosocial interventions delivered at the individual, caregiver, and/or family level (including … Comparator The comparison condition as defined in the respective studies, including active controls ( … We will design data abstraction forms to gather pertinent information from each article, including

2466. Single-arm studies in comparative effectiveness reviews (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/single-group-studies_white-paper.pdf
      January 01, 2013 - Ten of 21 did not provide the rationale for including single group studies. … A number of study types would be included in this category, including investigations described as ― … single group studies 11/21 (52) Stated rationale for including single group studies for benefits 6 … /11 (55) Stated rationale for including single group studies for harms 8/19 (42) Methods Planned … However, the rationale for including these designs is infrequently reported and the methods relevant

2467. Prostate-Cancer-Test Research-Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-test_research-protocol.pdf
      October 14, 2011 -  Intermediate outcomes, including improved decisionmaking in selecting patients for biopsy that leads …  Long-term health outcomes (clinical utility), including reduced mortality/ morbidity and improved …  Intermediate outcomes, including improved decisionmaking in selecting patients for biopsy that leads …  Long-term health outcomes (clinical utility), including reduced mortality/ morbidity, improved quality …  Long-term health outcomes of interest, including reduced morbidity/mortality, improved quality

2468. Omega-3 Fatty Acids and Maternal and Child Health: An Update (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/omega-3-maternity_executive.pdf
      October 01, 2016 - Introduction The n-3 FA (including alpha linolenic acid [ALA], stearidonic acid [SDA], eicosapentaenoic … Along with the n-6 FA (including linoleic acid [LA] and arachidonic acid [AA]), they are involved … Eicosanoids (including AA, prostaglandins, thromboxanes, and leukotrienes) have wide ranges of physiologic … We identified ten RCTs of pregnant women that reported cognitive outcomes in their offspring (including … Six RCTs, including two from the original review, reported on supplementation for lactating women, including

2469. Effective Health Care (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0309_05-03-2008.pdf
      January 01, 2008 - The scope of this topic, including populations, interventions, comparators, and outcomes, will be further

2470. Disposition of Comments for CER 208 Treatment for Bipolar Disorder in Adults A Systematic Review (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-208-bipolar-adults-disposition-comments.pdf
      August 07, 2018 - TEP Reviewer #3 It is obvious that a great deal of effort went into the creation of this report, including … paragraphs on bipolar II and NOS to include more information on diagnostic criteria and variants including … Other unique references might be retrieved by including search terms for "affective disorder". … Unfortunately, the study addressed depression treatment but the study duration (including followup … Due to this variation, comparisons of different modalities including individual versus group studies

2471. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/angina-heart-attack-treatments_research-protocol.pdf
      December 11, 2012 - clinical data, a number of questions remain about the use of antiplatelet and anticoagulant agents, including … • What are the optimal timing, dosing strategy, and duration of antiplatelet agents (including aspirin … The safety outcomes will be framed to help identify adverse events, including adverse drug reactions … The Task Order Officer reviewed contract deliverables for adherence to contract requirements, including … those undergoing coronary stenting and in patients with ACS (UA/NSTEMI), including patients who are

2472. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/atrial-fibrillation_research-protocol.pdf
      May 22, 2012 - the Institute called upon researchers to compare the effectiveness of treatment strategies for AF, including … We will use several approaches to identifying relevant gray literature, including requests to drug and … The safety outcomes will be framed to help identify adverse events, including those from drug therapies … These studies adhered to the commonly held concepts of high quality, including the following: a clear … The Task Order Officer reviewed contract deliverables for adherence to contract requirements, including

2473. Methods Research Report: Linking Evidence Reviews to Organizational Guideline Planning: A Pilot Test of an Interactive Web-Based Presentation and Discussion of Evidence (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/linking-evidence-reviews-methods_0.pdf
      October 01, 2018 - At this time, they expressed an interest in cardiovascular-related (including diabetes) topics. … Participants were a mix of clinicians (including nurses) and administrators. 2) Be interactive rather … The third unique aspect was the use of a formally structured interactive process, including pre-seminar … They also wanted more information about subgroups, including notes about when 8 subgroup data are … Do the benefits of these interventions outweigh the harms (including opportunity cost and financial

2474. Preterm-Birth-Terbutaline-Pump Surveillance (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/preterm-birth-terbutaline-pump_surveillance.pdf
      January 30, 2013 - conservative treatment, or other interventions: Key Question 1: improve neonatal health outcomes, including … Key Question 2: improve other surrogate outcomes, including gestational age at delivery, incidence of … Key Question 2: improve other surrogate outcomes, including gestational age at delivery, incidence of … Key Question 2: improve other surrogate outcomes, including gestational age at delivery, incidence of … Key Question 2: improve other surrogate outcomes, including gestational age at delivery, incidence of

2475. Preterm-Birth-Terbutaline-Pump Surveillance (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/preterm-birth-terbutaline-pump_surveillance.pdf
      January 30, 2013 - conservative treatment, or other interventions: Key Question 1: improve neonatal health outcomes, including … Key Question 2: improve other surrogate outcomes, including gestational age at delivery, incidence of … Key Question 2: improve other surrogate outcomes, including gestational age at delivery, incidence of … Key Question 2: improve other surrogate outcomes, including gestational age at delivery, incidence of … Key Question 2: improve other surrogate outcomes, including gestational age at delivery, incidence of

2476. Medical Therapies for Children With Autism Spectrum Disorder—An Update (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/asd-medical-executive-170505.pdf
      May 01, 2017 - Harms of these agents, including extrapyramidal symptoms and weight gain, were also clinically significant … Clinically significant side effects were associated with methylphenidate including aggressive behavior … Data were inadequate to assess effects of risperidone plus adjunctive agents including amantadine, … Most of the studies reported including children with at least moderate level of severity of ASD. … Studies of stimulants included children with cognitive impairment and with comorbidities including

2477. Long-Term-Care-Adults Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/long-term-care-adults_executive.pdf
      November 01, 2012 - Care through HCBS may be provided in a variety of settings, including recipients’ homes; group living … and people with physical disabilities.11 States have options for financing HCBS through Medicaid, including … To identify additional reports, we searched grey literature sources including Web sites of relevant … We compared HCBS (including AL) recipients with NH residents across the domains of physical function … Comparisons of outcome trajectories must take into account differences in care environments, including

2478. S58 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/s58.pdf
      October 01, 2007 - Finally, we discuss policy implications, including the potential for the research use of Medicare Part … Supports detailed analyses of subgroups, rare conditions and comorbidities, including individuals with … Strong representation of vulnerable populations including racial/ethnic minorities. … Measures can be distinguished on several dimensions including contin- uous versus dichotomous measures … These analyses require multiple types of expertise including knowledge of the conditions, populations

2479. Adverse Effects of First-Line Pharmacologic Treatments of Major Depression in Older Adults (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-depression-research-protocol.pdf
      February 07, 2018 - Contextual Question: In older adults with major depressive disorder, including subgroups of interest … dose, frequency, and concomitant medications), outcome measures, and the results of each outcome, including … All studies, including those that are not amenable to pooling, will be qualitatively summarized. … Tests for funnel plot asymmetry, including Egger’s weighted regression tests for continuous outcomes21 … Impact of including or excluding both-armed zero-event studies on using standard meta-analysis methods

2480. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/pressure-ulcer-prevention_research-protocol.pdf
      January 10, 2012 - Numerous factors that increase the risk of developing pressure ulcers have been identified, including … risk, sex and age, continence, mobility, Malnutrition Screening Tool score, and special risk factors including … Source: www.effectivehealthcare.ahrq.gov Published Online: January 10, 2012 4 *Including acute … Key Questions Literature Sources We will search Ovid MEDLINE ® , CINAHL ® , EBM Reviews, including … Key Informants Key Informants are the end-users of research, including patients and caregivers,