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81. rheumatoid-arthritis-medicine-update-protocol-170515 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine-update_research-protocol.pdf
    May 15, 2017 - the pathogenesis of RA.6 Environmental risk factors associated with RA, though not well understood, include … We will include these drugs in the literature search, including those under review in the event they … We will include studies with mixed populations if more than 50 percent of the study populations had … If we do not receive a response, we will not include the study in question. … We will also search the gray literature for unpublished studies relevant to this review and include

82. BLUEPRINT FOR A FUTURE DISTRIBUTED RESEARCH NETWORK (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/distributed-network-blueprint_research.pdf
    June 01, 2010 - Potential uses of a distributed research network include: • Evaluation of medical product utilization … Network governance must include development of policies and procedures to address issues such as data … This could include maintenance of network infrastructure, documentation, coordination, monitoring of … Functionality (Phase 1) In phase 1, functionality should include the ability to securely distribute … New data sources could include additional health plans with administrative and claims data.

83. worker-health-protocol-150526 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/worker-health_research-protocol.pdf
    May 26, 2015 - TWH interventions include, for example, strategies aimed to both increase physical activity and prevent … Third, many contextual factors affect worker health; these include, for instance, health care coverage … Contextual factors may include (but are not limited to) the following: legal- regulatory environment … These include questions to assess selection bias, confounding, performance bias, detection bias, and … Some factors identified a priori that may limit the applicability of evidence include the following

84. Methods Guide for Comparative Effectiveness Reviews - Avoiding Bias in Selecting Studies (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-bias_methods.pdf
    February 01, 2013 - A systematic review starts with a broad comprehensive search and the choice of which studies to include … Reviewer chooses to include only Class III and IV heart failure and finds that the intervention is … guidance for considering eligibility of studies that include commingled or ill-defined settings. … deciding to include observational studies, EPCs need to take special care in developing and testing … Reviewers often include other study design or reporting characteristics as eligibility criteria.

85. Registry of Patient Registries (RoPR): Project Overview (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/registry-of-patient-registries_research-2012-3_0.pdf
    January 01, 2012 - The RoPR record will include additional patient registry data elements identified by the stakeholders … The RoPR will include descriptive information on the data being collected, particularly with respect … This descriptive information will describe the registry as a whole, and will not include patient level … In this hybrid model, the solution would include changes to be implemented within ClinicalTrials.gov … The RoPR record will include additional patient registry data elements identified by the stakeholders

86. Updating the Framework for AHRQ’s National Healthcare Quality and Disparities Report (NHQDR) (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/updating-framework-protocol.pdf
    September 06, 2023 - Settings of care covered include ambulatory care, health centers, emergency departments, hospitals, … • Are there existing frameworks that include social determinants of health? … Publications that do not address quality of care in detail but include quality of care and health equity … The synthesis for the technical brief will include summary tables and figures to clearly convey the … They may include clinical experts, patients, manufacturers, researchers, payers, or other perspectives

87. Evidence-based Practice Center Systematic Review Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/case-management_research-protocol.pdf
    June 06, 2011 - Key components of case management include planning and assessment, coordination of services, patient … Patient health outcomes (include but are not limited to): overall quality of care; disease- specific … We will include observational studies, systematic reviews, and clinical trials. … Clinical criteria include principal diagnosis and medication complexity. … Few of the studies include sub-group analyses.

88. Evidence Report on the (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/antidepressants-update_research-protocol.pdf
    July 13, 2011 - Pharmacotherapy dominates the medical management of depressive disorders and may include first-generation … These second-generation treatments include selective serotonin reuptake inhibitors (SSRIs) and serotonin … The first review did not include desvenlafaxine (listed below) as this is a new approved treatment since … As our review focuses on adults, we will exclude those that include children or adults. … When differences between the reviewers arise, we will include studies for full-text review.

89. Methods Guide for Medical Test Reviews Chapter 6 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-applicability_methods.pdf
    July 01, 2012 - Or include but: − Flag missing elements in tables/text. … Or include but: − Contact authors for clarification. … Or include but: − Restrict to specified comparators. … Or include but: − Flag deficits in tables/text. − Discuss implications. … Or include and: − Contact authors for information. − Flag deficits in tables/text.

90. depression-pregnancy-postpartum-protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/depression-pregnancy-postpartum_research-protocol.pdf
    March 29, 2013 - and occasionally by potentially life-threatening psychosis.11 General risk factors for depression include … Additional factors associated with depression in pregnant women include younger age, non-Latino ethnicity … The combinations include: i. … The combination include: (a) Using a second drug to augment the effects of the primary drug and … Interventions Interventions include commonly used antidepressant drugs.

91. Emergency Medical Service/911 Workforce Infection Control and Prevention Issues (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/ems-911-workforce-protocol.pdf
    January 01, 2015 - Standard infection prevention and control (IPC) measures for emergency medical service (EMS) workers include … (Outcomes of interest include but are not limited to, incidence, prevalence, duration, severity, missed … (Outcomes of interest include but are not limited to, incidence, prevalence, duration, severity, missed … The EMS workforce will include the responding health care personnel in field settings. … They may include clinical experts, patients, manufacturers, researchers, payers, or other perspectives

92. Tonsillectomy Research-Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/tonsillectomy_research-protocol.pdf
    February 10, 2016 - We  will  include  studies  published  in  English  only.   … Studies  addressing  KQ1b  will   include  children  between  1  and  2  years  old.     … We  will  screen  and  include  relevant  studies  with  each  update.   … Agents  include  montelukast  and  zafirlukast.     … Opioid  analgesics:  Opioid  analgesics  used  after  tonsillectomy  include  tramadol.  

93. Telehealth for Women (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/telehealth-women-protocol.pdf
    June 21, 2021 - Virtual health technologies, also considered telehealth services, may include mobile health applications … Reproductive health services considered for this review include family planning, contraception, and … For this review, family planning services include preconception counseling (including birth spacing) … We will include qualitative studies that evaluate preferences, barriers/facilitators. … We will review existing systematic reviews, and include their results if appropriate.

94. autism-update-protocol-130920 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/autism-update_research-protocol.pdf
    September 20, 2013 - along with restrictive, repetitive, and stereotypical behaviors and activities.1 Features of ASD can include … The manifestation and severity of symptoms of ASD differs widely, and treatments include a range of … CAM approaches are widely used despite little available evidence on efficacy, and include therapies … Individual goals for treatment vary for different children and may include combinations of therapies … The form also will include a field in which to report the funding source of a study.

95. Kidney-Stone-Prevention Research-Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/kidney-stone-prevention_research-protocol.pdf
    June 15, 2011 - In large observational studies, dietary factors associated with increased risk of nephrolithiasis include … Controversies include whether pretreatment laboratory test results predict effectiveness of treatment … Additional search strategies may include forward citation searching of included RCTs and systematic … Grey literature searching may include searches of regulatory data, trial registries, and abstracts … These materials may include regulatory documents and reports of conducted trials.

96. Evidence-based Practice Center Systematic Review Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/therapies-for-autism-spectrum-disorder-2-9-2010.pdf
    January 01, 2010 - prenatal drug exposure, among others, have been investigated.2 Disorders within the autism spectrum include … Settings will include medical, other clinical therapy settings, the home, and the educational setting … The form also will include an opportunity to report on funding source. … Rationale: Many studies include both children and adolescents, and few separate results in such a way … Rationale: Many studies include both children and adolescents, and few separate results in such a way

97. Evidence-based Practice Center Systematic Review Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/undescended-testicle_research-protocol.pdf
    September 02, 2011 - Imaging approaches include magnetic resonance angiography, which requires sedation or anesthesia and … Published Online: September 2, 2011 Associated conditions and consequences of cryptorchidism include … Longer term consequences of cryptorchidism include testicular malignancy and infertility/subfertility … For example, for a cohort study, the fundamental criteria will include: representativeness of cohort … Other sources of bias can include baseline imbalances, source of funding, early stopping for benefit

98. Evidence-based Practice Center Systematic Review Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/autism_research-protocol.pdf
    December 09, 2009 - prenatal drug exposure, among others, have been investigated.2 Disorders within the autism spectrum include … Settings will include medical, other clinical therapy settings, the home, and the educational setting … The form also will include an opportunity to report on funding source. … Rationale: Many studies include both children and adolescents, and few separate results in such a way … Rationale: Many studies include both children and adolescents, and few separate results in such a way

99. Nonpharmacologic Treatment for Maternal Mental Health Conditions (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/mental-health-pregnant-protocol.pdf
    August 24, 2023 - In the general population, nonpharmacologic interventions for PTSD can include exposure therapy, trauma … We will include studies of the above that directly compare different mechanisms of delivery below. … We will include filters to remove nonhuman studies and articles that are not primary RCTs or SRs. … We will however include a list of these studies with key characteristics and findings in an appendix … We will include summaries of SR findings and conclusions written for nontechnical readers.

100. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/ace-inhibitor-arb-update_research-protocol.pdf
     May 07, 2010 - We will include studies with patients of mixed ages and mixed diagnoses only if results were reported … • Interventions and Comparators of Interest: • The interventions include the medications listed … For each abstract, please mark either “EX” for Exclude, “IN” for Include or “Rev” for Review. … “ACE inhibitors” or unspecified “ARBs” vs. unspecified “ACEIs” - Include ACEI + drug X vs. … Specifically for this project, the data abstraction forms will include data required to evaluate the