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461. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/gerd-disposition-120104.pdf
     April 01, 2011 - The tables below include the responses by the authors of the review to each comment that was submitted … but it is not clear to the average reader) The body of the executive summary has been edited to include … s study goes through such a protocol, but does not include a placebo group and follows a cough cohort … Future research needs may also include careful evaluation of potential predictors of response in the … We agree that the title should include “…Adults with GERD…”.

462. Disposition of Comments Report for Outpatient Case Management for Adults With Medical Illness and Complex Care Needs (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/case-management_disposition-comments.pdf
     January 01, 2013 - The tables below include the responses by the authors of the review to each comment that was submitted … Our search was designed to include all subpopulations with any medical illness and complex care needs … Search strategy is appropriate; however it would have been advantageous to include a rationale why … Unclear if functions of case managers listed in last paragraph on Page 20 include an exhaustive list … Key components of CM include planning and assessment, coordination of services, patient education,

463. Emerging MRI Technologies for Imaging Musculoskeletal Disorders under Loading Stress (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/musculoskeletal-disorders-imaging_disposition-comments.pdf
     November 01, 2011 - The tables below include the responses by the authors of the review to each comment that was submitted … No explicit PICOD was presented but was mentioned as a basis for include information for studies for … Peer Reviewer 3 (Results) Findings, page 31, lines 23-24 I assume these stats include comparative … We have expanded the Table of methodological issues to include items suggested by the reviewer. … We have expanded the original list of recommendations to include the reviewer’s suggestions.

464. Noninvasive, Nonpharmacological Treatment for Chronic Pain (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/nonpharma-treatment-pain_research-protocol-amended.pdf
     September 20, 2017 - Other challenges related to the evidence and its synthesis include: (1) the most appropriate outcomes … To facilitate this, major decisions and related rationale include: • Exclusion of studies evaluating … To include such comparisons would expand the scope and add to the complexity of the report. … • We recognize that interventions such as formal exercise programs may include components of other … Evidence tables will also include relevant studies from the prior low back pain review as appropriate

465. Renal Artery Stenosis Management Strategies: An Updated Comparative Effectiveness Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-update_disposition-comments.pdf
     August 16, 2016 - The tables below include the responses by the authors of the review to each comment that was submitted … The executive summary does not include references to tables, figures, appendixes, etc. … We need to include the strength of evidence in the abstract, but did not want to be overly repetitive … We acknowledge that our review does not include all evidence that may have a bearing on the topic. … We have added that the STAR trial was the only trial to explicitly include patients with CHF (~10%)

466. Ch 8-User-Guide-To-Ocer 130129 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/ch_8-user-guide-to-ocer_130129.pdf
     October 01, 2013 - Important considerations for choosing data include whether or not the key variables are available to … Patients are typically identified when they present for care, and the data collected generally include … Examples of CER studies that make use of this linked data include an evaluation of the effectiveness … Some EHRs include other features, such as flow sheets of clinical results, particularly those results … Pharmacy Data Outpatient pharmacy data include claims submitted to insurance companies for payment

467. Undescended-Testicle Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/undescended-testicle_executive.pdf
     December 01, 2012 - Imaging approaches include ultrasonography (US), computerized tomography (CT) scanning, routine magnetic … Areas of uncertainty include selecting the optimal approach to treatment planning (imaging vs. … Intermediate outcomes include psychological benefits in terms of body image, and long- term goals include … For the treatment questions (KQ2 and KQ3), however, studies had to include an appropriate comparison … Theoretically, harms of imaging could include exposure to radiation or to contrast, but data on harms

468. Strategies to De-escalate Aggressive Behavior in Psychiatric Patients (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/aggression_disposition-comments.pdf
     July 14, 2016 - The tables below include the responses by the authors of the review to each comment that was submitted … Perhaps just a brief statement similar the one used in Discussion “which include multiple commponents … These include patient-centered ones (e.g., environmental interventions, strategies to decrease use … These include quality of life, functioning or patient experience; improved therapeutic relationship; … Recommended areas of study include the following: • Does engaging patients in their own treatment

469. Pharmacologic Management of Acute Pain by EMS in the Prehospital Setting Protocol Amendment (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/acute-pain-ems-protocol-amendment.pdf
     January 28, 2019 - This group could include physicians,12 mobile intensive care units,13 helicopter teams,14,15 and military … Potential issues include direct harms of prehospital analgesia to the EMS provider themselves. … Analgesics include opioids (morphine or fentanyl), ketamine, nitrous oxide/oxygen, NSAIDs (ketorolac … Analgesics include opioids (morphine or fentanyl), ketamine, nitrous oxide/oxygen, NSAIDs (ketorolac … Evidence overview tables will include effect estimates and confidence intervals where quantitative

470. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/pressure-ulcer-prevention_research-protocol.pdf
     January 10, 2012 - PICOTS Criteria Population(s) Include:  KQs 1 and 2: All adult patients, ages >18 years … 5  Nonpreventive treatment interventions (covered in a separate review) Comparators Include … within the same category; e.g., alternating pressure mattress vs. foam overlay) Outcomes Include … †Patient characteristics include age, race or skin tone, physical impairment, body weight, specific medical … Settings Include:  Acute care hospital, long-term care facility, rehabilitation facility,

471. Standardized Library of Atrial Fibrillation Outcome Measures (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/white-paper-library-afib.pdf
     November 15, 2018 - • Fast Healthcare Interoperability Resources (FHIR) for evidence for the outcome: These include labs … • FHIR for additional relevant events: These might include procedures, encounters, etc. • Temporal … Lastly, some definitions did not include sufficient specificity to produce standardized definitions. … Procedure- related deaths include those related to a complication of the procedure or treatment for … to treatment or management of AF or associated complications, e.g., because-hospitalization doesn't include

472. The Facilitation Primer: Strategies, Tools & Considerations to Get You Started (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/stakeholders-engagement-others_research-2012.pdf
     January 01, 2012 - Attributes of an effective facilitator include: • • • • • Openness • • • • • Accessibility … of active listening Sense of humor Effective processes and structures employed by facilitators include … Project descriptions typically include a purpose statement, list of participants, AHRQ and its role, … It should include the date, time, call-in instructions (if applicable), objective for the meeting and … Some common concerns or situations requiring facilitator interruption include: • • • • • • •

473. Module II: Stakeholders and Stakeholder Engagement (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/module-ii-stakeholders-and-stakeholder-engagement.pdf
     June 01, 2011 - EHC Program stakeholders include: § Consumers, patients, caregivers, and patient advocacy organizations … Stakeholders also include individuals who nominate topics, helps develop research products, or disseminates … The benefits of engaging stakeholders in the research process include: § Increased clarity of research … Opportunities for involvement during the research process in the EHC Program include: § Suggest a research … For a Research Review, this might include help to focus the literature search, identify criteria, and

474. Radiotherapy-Proton-Beam Research (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/radiotherapy-proton-beam_research.pdf
     May 01, 2012 - by contractor regarding their indications for coverage of proton beam radiotherapy, but most LCDs include … A requirement that the medical record include evidence of benefit for proton beam radiotherapy over … Group 1 diagno- ses include cancers for which proton beam is considered medically reasonable in all … These estimates include only payments related to the use of the facility, equipment, and technician … Our estimates do not include payments to physicians for treatment planning and management, because

475. Transparency of Reporting Requirements: Management of Infertility (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-infertility_research-protocol.pdf
     September 02, 2016 - For feasibility reasons and to apply our methods to a range of interventions, we will include only KQ … Subpopulations of interest include groups differing in age; race/ethnicity; obesity/BMI; ovarian reserve … Subpopulations of interest include groups differing in age; race/ethnicity; obesity/BMI; ovarian reserve … Subpopulations of interest include groups differing in age, race/ethnicity, obesity/BMI, history of … Subpopulations of interest include groups differing by cause of male infertility (identified hormonal

476. Methods Guide for Medical Test Reviews Chapter 4 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-search_methods.pdf
     July 01, 2012 - A comprehensive search should include multiple databases and sources of grey literature. … In general, bibliographic searches for systematic reviews in health care should always include MEDLINE … Additional databases that are often useful to search include EMBASE®, CINAHL® and PsychINFO®. … In addition to published literature, a comprehensive search will include looking for unpublished or … Therefore, the search consisted of all possible variations on the names of these tests and did not need to include

477. Management of Infantile Hemangioma (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/infantile-hemangioma_clinician.pdf
     June 01, 2016 - These include: �� patients who have IH in functionally sensitive areas (e.g., eyes, liver, or airways … Currently available treatments include pharmacological in- terventions (such as beta-blockers and steroids … Steroids used to treat IH mainly include oral steroids and intralesional steroids (e.g., triamcinolone … ��The narrative review of the literature suggested that indications for referral include large lesion

478. Transparency of Reporting Requirements: Effectiveness of Treatments Options for the Prevention of Complications and Treatment of Symptoms of Diabetic Peripheral Neuropathy (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-neuropathy_research-protocol.pdf
     September 01, 2016 - Datasources and searching methods Datasources will include ClinicalTrials.gov and other standard electronic … Project staff will complete 2 sets of evidence tables: the first set will only include data from ClinicalTrials.gov … available from ClinicalTrials.gov; information could be the same as in published reports or could include … the information obtained with and without ClinicalTrials.gov, using summary evidence tables that include

479. Ch 9-User-Guide-To-Ocer 130129 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/ch_9-user-guide-to-ocer_130129.pdf
     September 21, 2012 - Studies in Epidemiology (STROBE) checklist asks investigators to report their rationale, which may include … - Types of hypotheses include equivalence, noninferiority, inferiority. o Specify the statistical … - Examples include Stata, Confidence Interval Analysis, Power Analysis and Sample Size ( … Special situations include: - The investigators anticipate that strong confounding that will eliminate

480. Options for Developing a Web-Based Forum on Patient Registries (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/registries-forums_research_0.pdf
     May 01, 2014 - Cost drivers include the type of sponsor (a Federal agency sponsor introduces additional administrative … Secondary goals that stakeholders have for the CoP include facilitating networking, interaction, and … Speakers may include CoP staff or invited guest speakers, such as authors of publications related to … Do not include information on participation history in the directory. … The charter should define the CoP’s purpose and scope (which may include providing the definition of