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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan54/colorectal-cancer-screening-june-2016
April 17, 2014 - screening programs based on any of the following screening tests (alone or in combination) in reducing a) incidence … standard
KQ 3: No comparator necessary
Outcomes
KQ 1: Colorectal cancer incidence … incidental findings on CT colonography; radiation exposure per CT colonography examination
KQ 1: Incidence
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/nfP93-Hva3bvxkvkBStTgm
Comparison:
Two-step screening
for syphilis with a
Benefits:
Vertical
transmission of
syphilis (incidence … (traditional or
reverse sequence
algorithms)
Benefits:
Vertical
transmission of
syphilis (incidence … Benefits:
Vertical
transmission of
syphilis (incidence
of congenital
syphilis);
prevalence of
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/Nvjr8BPsZhy4XGc7-rGjAH
June 18, 2018 - Screening women
aged 21 to 65 years substantially reduces cervical cancer incidence and mortality. … To further reduce the incidence and mor-
tality of cervical cancer, it is necessary to find effective … of transient HPV infection in younger women, even
though cervical cancer incidence is lower in this … cancer in older women and whether
the pattern of cervical cancer incidence differs in screened vs un … Vital signs: cervical
cancer incidence, mortality, and screening—United
States, 2007-2012.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/prostate-cancer-screening-adults
December 21, 2023 - for prostate cancer vs. no screening or usual care on short- or long-term prostate cancer mortality, incidence … early-stage prostate cancer vs. active surveillance or watchful waiting on prostate cancer mortality, incidence … morbidity (i.e., bone pain from metastases and urinary obstruction); functioning, quality of life, and incidence
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/-6kN7TPcfEj2owG4GTN2jA
June 01, 2012 - RATIONALE
Importance
The age-adjusted annual incidence rate of cervical can-
cer is 6.6 cases per 100 … The current annual
incidence rate is 6.6 cases per 100 000 women, and the
age-adjusted mortality rate … Because of the low incidence of high-
grade precancerous lesions and cervical cancer in ade-
quately … of cervical cancer incidence
and mortality. … The USPSTF agrees that the greatest effect on cervi-
cal cancer incidence and mortality would result
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/r7JMWkKKv2krN6cxKQUUfP
January 01, 2010 - evidence from multiple
observational studies that screening with cervical
cytology (Pap smears) reduces incidence … The yield of screening is low in previously screened
women older than 65 due to the declining incidence … Data on natural history of HPV infection and
the incidence of high-grade lesions and cervical
cancer … Despite falling incidence,
cervical cancer remains the tenth leading cause of
cancer death.10 The Healthy … In the U.S., peak
incidence and prevalence of HPV infection occur
among women younger than 25, but most
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www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/sexually-transmitted-infections
January 16, 2025 - Active intervention (i.e., comparative effectiveness)
Outcomes
KQ 1 (Health outcomes) :
STI incidence … avoiding sex while intoxicated with alcohol or other substances)
KQ 3 (Harms):
Increase in STI incidence
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/sexually-transmitted-infections
May 01, 2025 - Active intervention (i.e., comparative effectiveness)
Outcomes
KQ 1 (Health outcomes) :
STI incidence … avoiding sex while intoxicated with alcohol or other substance)
KQ 3 (Harms):
Increase in STI incidence
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/Nq6dYEj2eZxLhVhBrWCD-j
July 01, 2024 - screen-detected bladder cancer;
• the accuracy of urine screening tests;
• the effect of screening on the incidence
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/perinatal-depression-interventions-to-prevent
June 01, 2023 - required for medication trials
Outcomes
KQ 1:
Maternal health outcomes:
Depression incidence … or symptoms (required)
Suicide deaths, attempts, or ideation, including self-harm
Anxiety incidence
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/cervical-cancer-screening-adults-adolescents
March 17, 2022 - strategies (i.e., test, mode of collection, and interval of testing) on precancer detection, cancer incidence … trauma, smoking, or vaccination status) that contribute to inequities in cervical cancer screening, incidence
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/syphilis-infection-in-pregnancy-screening-september-2018
September 04, 2018 - Although national rates of syphilis infection among pregnant women are not currently available, the incidence … During the same time, the incidence of adverse pregnancy outcomes decreased from 42.7% to 19.2%, and … the incidence of stillbirth or fetal loss decreased from 19.0% to 3.3%. … Increase in incidence of congenital syphilis—United States, 2012-2014. … Incidence and risk factors for the prozone phenomenon in serologic testing for syphilis in a large cohort
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/ZSVRTLv938Gtr5au4-6eYL
September 01, 2024 - Mandelblatt, MD, MPH
IMPORTANCE The effects of breast cancer incidence changes and advances in screening … Five of the 6 models adapted an age-period-cohort modeling
approach to estimate breast cancer incidence … without screening
Age-period-cohort model using SEER
breast cancer incidence with a period
effect for … A Bayesian
simulation model for breast cancer screening,
incidence, treatment, and mortality. … Changing patterns in breast cancer incidence
trends.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/lung-cancer-screening
August 16, 2018 - Does screening for lung cancer with low-dose computed tomography (LDCT) change the incidence of lung … of change in all-cause and lung cancer mortality that results from a specified change in lung cancer incidence … other eligibility criteria
KQs 1–3, 8: Studies without a comparison group
Outcomes
KQ 1a: Incidence … benign nodule), and harms of workup (e.g., biopsy leading to an adverse event)
KQ 6: 5- and 10-year incidence
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/ghbfx9e3A6jQEqVW26y8Jv
March 09, 2021 - MAIN OUTCOMES AND MEASURES Lung cancer incidence, lung cancer mortality, all-cause
mortality, test accuracy … The NLST found a reduction in
lung cancer mortality (incidence rate ratio [IRR], 0.85 [95% CI, 0.75-0.96 … Does screening for lung cancer with LDCT change the incidence of lung cancer and the distribution of … Mortality, survival and incidence
rates in the ITALUNG randomised lung cancer
screening trial. … Results of the
two incidence screenings in the National Lung
Screening Trial.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/diabetes-mellitus-type-2-in-adults-screening-2008
June 15, 2008 - Hemoglobin A 1c values in the high-normal range (5.6% to 6.0%) seem to predict a higher incidence of … Four treatments to reduce the incidence of CVD events among persons with diabetes have been studied in … Glycosylated hemoglobin predicts the incidence and progression of diabetic retinopathy. … UKPDS 50: risk factors for incidence and progression of retinopathy in Type II diabetes over 6 years … Incidence of sight-threatening retinopathy in patients with type 2 diabetes in the Liverpool Diabetic
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/skin-cancer-screening-behavioral-counseling-1996
January 01, 1996 - The authors noted that in Denmark, which has comparable incidence rates, the MM mortality in women rose … No studies on the effectiveness of counseling in reducing skin cancer incidence or mortality were found … Incidence of nonmelanoma skin cancer. Dermatol Clin . 1991;9:751–755. [ PubMed ] 5. … The incidence of malignant transformation in giant pigmented nevi. … Increasing incidence of cutaneous melanoma, ultraviolet radiation and the clinician.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/oral-health-children-adolescents-screening-preventive-interventions
June 17, 2021 - issues
Comparisons
No intervention or placebo
Active treatment
Outcomes
Dental caries (incidence … and severity) Periodontal disease in adults (incidence and severity) Tooth loss Morbidity Quality of
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/lipid-disorders-in-children-screening
August 19, 2021 - for FH or multifactorial dyslipidemia in asymptomatic children and adolescents delay or reduce the incidence … interventions, lipid-lowering medications, or both in children and adolescents delay or reduce the incidence
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www.uspreventiveservicestaskforce.org/uspstf/about-uspstf/reports-congress/eleventh-annual-report-congress-high-priority-evidence-gaps-clinical-preventive-services
January 01, 2021 - people who are socially and economically disadvantaged (for whom smoking prevalence and lung cancer incidence … Assess the factors that contribute to increased colorectal cancer incidence and mortality in Black adults