-
effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1406.pdf
June 01, 2014 - After 56 weeks of treatment, liraglutide provided statistically significant
improvements in all measures … effects was questioned by one expert representing a
research perspective, who commented, “Short term improvements … are promising however it is
unclear if these improvements will persist long term.”67 Multiple experts … clinical expert opined, “The weight loss likely to be seen with continued use will, for
some, lead to improvements … New data from Arena Pharmaceuticals' pivotal
BLOSSOM trial of lorcaserin demonstrate
improvements
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/medication-adherence-interventions_executive.pdf
September 01, 2012 - We found
relatively little evidence linking improved adherence to
improvements in other outcomes, such … These improvements were accompanied by
improvements in systolic and diastolic blood pressure
for case … All
other approaches failed to produce improvements and were
judged to be insufficient for lack of … interventions and case
management approaches offer the most consistent and
voluminous evidence of improvements … adherence among
individuals who had had no prescription drug coverage
before Medicare Part D and smaller improvements
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypertension-pulmonary-arterial_executive.pdf
April 01, 2013 - Calcium channel blockers are associated
with long-term (>1 year) improvements in hemodynamics
and functional … antagonists, phosphodiesterase inhibitors,
and prostanoids were associated with statistically
significant improvements … power to detect a difference in mortality;
however, a consistent direction of effect and demonstrated
improvements … The magnitude of these
statistically significant improvements in 6MWD associated
with treatment are
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-209-evidence-summary-non-pharma-chronic-pain.pdf
June 01, 2018 - Electromagnetic Field
• One trial found pulsed electromagnetic fields were
associated with slight improvements … • Hip Osteoarthritis: Manual therapy was associated with
slight improvements in short-term (mean difference … Headache
Manual Therapies
• Spinal manipulation therapy was associated with slight
to moderate improvements … therapy, and mind-body practices
were most consistently associated with durable slight
to moderate improvements
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ced-appendix-3.xlsx
June 24, 2022 - protocol describes study-specific objectives, which should include evidence generation to support improvements … across the network are good candidates for having thresholds that are raised or lowered to reflect improvements … protocol describes study-specific objectives, which should include evidence generation to support improvements
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-208-bipolar-evidence-summary.pdf
August 01, 2018 - However, most manic symptom
improvements were of modest clinical significance, with
values that were … However, improvements were of
modest clinical significance, with values that were less
than the MID
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/traumatic-brain-injury-rehabilitation-surveillance-160902.pdf
May 29, 2025 - Are"improvements"in"outcomes"achieved"via"multidisciplinary"postacute"
rehabilitation"for"TBI"sustained"over"time … $$
F"2$
Click$here$to$enter$text.$
$
Key(Question(4:(
Are$improvements$in$outcomes$achieved$via … $Key$Question$4:$Are$improvements$in$outcomes$achieved$via$multidisciplinary$postacute$rehabilitation … $Key$Question$4:$Are$improvements$in$outcomes$achieved$via$multidisciplinary$postacute$rehabilitation
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c_executive.pdf
November 01, 2012 - Key Question 4
Have improvements in intermediate outcomes (SVR,
histologic changes) been shown to reduce … Intermediate
Outcomes
Final Clinincal
Outcomes
● Sustained
virologic
response
● Histological
improvements … C (continued)
Key Question Outcome Summary of Evidence
Strength of
Evidence
Key Question 4
Have improvements … in settings
applicable to U.S. populations evaluated the association
between achieving an SVR and improvements
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-IV-sepsis.pdf
July 01, 2023 - intervention PSPs reported improvement in at least one process measure, however, only
two showed improvements
-
effectivehealthcare.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-1506.pdf
June 01, 2015 - selectively inhibiting URAT1, lesinurad is thought to promote urinary
excretion of uric acid leading to improvements … At 16 weeks, patients who received secukinumab 75 mg did
not have significant improvements in ASAS20 … Lesinurad is a selective inhibitor of URAT1 intended to promote urinary
excretion of uric acid leading to improvements
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/mental-health-children_research-protocol.pdf
December 11, 2015 - Managing clinical knowledege for healthcare
improvements. … primary synthesis
to examine set
relationships between
combinations of
strategy components
and improvements … All included studies had at least two arms but
did not always provide information on arm-specific improvements
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c-treatment-adherence_executive.pdf
September 22, 2011 - (Strength of evidence = insufficient)
• One small fair-quality RCT found greater
improvements in QOL … At 36 weeks, improvements were apparent in both scores
from baseline in group one, patients using epoetin … One poor-quality RCT and one poor-quality
cohort study provided evidence for QOL improvements
that
-
effectivehealthcare.ahrq.gov/sites/default/files/obesity_hi_impact.pdf
April 17, 2012 - The authors concluded, “Treatment with Contrave
resulted in significant improvements over placebo in … body weight as compared to 11% on placebo (p <0.0001); patients taking
Contrave showed significant improvements … They reported
improvements in fasting insulin and glucose levels and blood pressure for lorcaserin
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mental-illness-heart_executive.pdf
April 01, 2013 - Improvements in HbA1c were small. … • Small improvements in lipids were seen in one study of
ramelteon, one study of topiramate, and … are largely consistent with our findings
that behavioral interventions are associated with small
improvements
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-treatment-ssri_surveillance.pdf
January 01, 2013 - There were
significant improvements at
12 weeks for both groups,
with no differential group
effect … kg
per week
(KKW) vs
exercise of 4
KKW
Cooper
Institute,
12 weeks
There were
significant
improvements
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-247-interventional-treatments-acute-chronic-pain-evidence-summary_0.pdf
September 01, 2021 - and small to large improvement in function versus sham
radiofrequency at 1 month (2 trials, N=79); improvements
-
effectivehealthcare.ahrq.gov/products/learning-health-systems-panel/overview
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/surveillance-report-2-noninvasive-nonpharma.pdf
April 01, 2022 - practices, and mind-body practices were
most consistently associated with durable small to moderate improvements … Interventions or comparators for which there was low strength of evidence of no effect for
improvements … Spinal manipulation was associated with improvements in function and pain short term
compared with sham
-
effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/epc-maternal-health-grand-rounds-slides.pptx
January 01, 2023 - Reminders, clinical decision support
25
Key Question 2
Does extension of health insurance coverage or improvements
-
effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1412.pdf
December 01, 2014 - After 56 weeks of treatment, patients taking the
drug had statistically significant improvements in … was questioned by one expert representing a health
systems perspective, who commented, “Short term improvements … are promising however it is
unclear if these improvements will persist long term.”71 Multiple experts … mg data showed
weight-loss efficacy across a range of baseline
BMI categories, and significant improvements