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effectivehealthcare-admin.ahrq.gov/products/asd-medical/research-2017
January 01, 2021 - Key Messages
Despite many randomized trials, confidence in reported improvements (strength of evidence … to placebo, seven studies addressing risperidone or aripiprazole reported statistically significant improvements … N-acetylcysteine and tetrahydrobiopterin were not associated with improvements in social skills and symptom … Methylphenidate and atomoxetine were also associated with improvements in hyperactivity in small short-term … RCTs (low SOE), with improvements maintained over 6 months for atomoxetine (low SOE for longer term
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effectivehealthcare-admin.ahrq.gov/products/integrated-pain-management/research
October 01, 2022 - Compared with usual care or waitlist, IPMPs were associated with small improvements in pain in the short … CPMPs were associated with small improvements in pain immediately postintervention (SOE: moderate) but … no differences in the short, intermediate, and long term (SOE: low); for function, improvements were … in function but no improvements in pain in the short term when compared with physical activity alone … IPMPs and CPMPs may provide small to moderate improvements in function and small improvements in pain
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effectivehealthcare-admin.ahrq.gov/products/ankyloglossia/research
December 01, 2019 - Four RCTs reported improvements in breastfeeding efficacy using either maternally reported or observer … Three studies with significant limitations reported improvements in other feeding outcomes with frenotomy … Three poor-quality comparative studies noted some improvements in social concerns and gains in tongue … Conclusions
A small body of evidence suggests that frenotomy may be associated with improvements in … Comparative studies reported improvements in some measures of speech, but assessment of outcomes was
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effectivehealthcare-admin.ahrq.gov/products/autism-update/research
December 01, 2019 - timeframes was associated with improvement in cognitive functioning and language skills (moderate SOE for improvements … behavioral therapy on anxiety reported positive results in older children with IQs ≥70 (high SOE for improvements … Smaller short-term studies of other interventions reported some improvements in areas such as sleep and … Despite improvements in the quality of the included literature, a need remains for studies of interventions … across settings and continued improvements in methodologic rigor.
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effectivehealthcare-admin.ahrq.gov/products/nonpharma-treatment-pain/research-2018
December 01, 2019 - Improvements in pain continued into intermediate term for exercise, massage, and yoga (moderate effect … Osteoarthritis: For knee osteoarthritis , exercise and ultrasound demonstrated small short-term improvements … acupuncture (SOE: moderate), CBT, tai chi, qigong, and exercise (SOE: low) were associated with slight improvements … intermediate term for exercise (SOE: moderate), acupuncture, and CBT (SOE: low), slight functional improvements … In the long term, small improvements in function continued for multidisciplinary rehabilitation but not
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND-0775-150722.pdf
May 12, 2015 - ., different dosage of the same
antipsychotic)
Outcome(s): Social, occupational and functioning improvements … ; improvements
Topic Number(s): 0622
Document Completion Date: 05-12-15
1
http://effectivehealthcare.ahrq.gov … ability to live independently; harms
of treatments (e.g., diabetes mellitus, extrapyramidal symptoms);
improvements … dosage of the same non-
pharmacological treatment)
Outcome(s): Social, occupational and functioning improvements … ; improvements
in health-related quality of life; reductions in hospitalizations;
reductions in self-harm
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effectivehealthcare-admin.ahrq.gov/products/noninvasive-nonpharm-pain-update/research
September 01, 2022 - Chronic low back pain : Psychological therapies were associated with small improvements compared with … Osteoarthritis pain : Exercise resulted in small improvements in function and pain at short-term (SOE … Small improvements in function and pain with exercise were seen for hip osteoarthritis short term (SOE … Fibromyalgia : Functional improvements were seen with exercise, mind-body practices, multidisciplinary … Long term, functional improvements persisted for multidisciplinary rehabilitation without improvement
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effectivehealthcare-admin.ahrq.gov/products/diabetes-mobile-devices/technical-brief
March 01, 2019 - Of the 11 apps, studies showed only 5 were associated with clinically significant improvements in HbA1c … Telesage; For Type 2 diabetes- Blue Star, WellTang, Gather Health)
None of the studies showed patient improvements … Patients using two apps for type 1 diabetes experienced improvements in hypoglycemic episodes. … Patients did not experience improvements in quality of life, blood pressure, weight, or body mass index
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effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/in-patients-with-cerebral-palsy-cp-and-difficulties-with-feeding-what-is-the-effectiveness-of-of-anti-reflux-procedure-since-often-done-in-conjunction-with-gastrostomy-placement-or-type-of-tube-j-tube-or-g-j-tube-versus-typi
November 01, 2017 - (For example, improvements in patient symptoms or problems from treatment or diagnosis.) … Improvements in primary outcomes such as growth, quality of life, functional improvements, participation … Improvements in other outcomes such as nutritional status, decreased time spent in feeding-related activities … Improvements in delivering nutrition to patients with impaired oral feeding have increased the options
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effectivehealthcare-admin.ahrq.gov/products/fecal-incontinence/research
December 01, 2019 - or without electrostimulation on FI severity (PFMT-BF -5.4 vs. dextranomer -4.6 point Vaizey score improvements … Surgical improvements varied. … Most current interventions show modest improvements in FI outcomes that meet minimal important differences
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/executive-summary-2017-schizophrenia-adult.pdf
January 01, 2017 - Ideally, improvements in symptoms
translate to long-term, clinically relevant, positive changes
in … Benefits Outcomes for Key Questions 1 and 2
• Functional
– Improvements in social and occupational … Women had
greater improvements than men in core illness symptoms
with clozapine and in quality of life … Cognitive behavioral therapy (CBT) resulted in
improvements in global function and quality of life ( … SGA comparisons
Core Illness Symptoms:
Improvements in Negative
Scale Scores
• Olanzapine was more
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effectivehealthcare-admin.ahrq.gov/products/nonopioid-chronic-pain/research
June 01, 2022 - anti-inflammatory drugs (NSAIDs) (for osteoarthritis and inflammatory arthritis) were associated with mostly small improvements … improvement in quality of life was seen with duloxetine in patients with neuropathic pain, and small improvements … showed memantine moderately improved pain, function, and quality of life in patients with fibromyalgia; improvements … In the short term, small improvements in pain and/or function were seen with SNRI antidepressants for
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/autism-update_executive.pdf
August 01, 2014 - Improvements were most often seen in cognitive abilities
and language acquisition, with less robust … Children’s
symptom severity often decreased during treatment, but
these improvements often did not … exceeded improvements related to the
impact of ameliorated anxiety itself. … Limitations of the Evidence Base
Despite improvements, the existing literature still has
significant … across settings and continued
improvements in methodologic rigor.
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effectivehealthcare-admin.ahrq.gov/products/asd-interventions/research-2017
January 01, 2021 - Key Messages
Some interventions may yield modest short-term (<6 months) improvements in some outcomes … Conclusions
Some interventions targeting sensory challenges may produce modest short-term (<6 months) improvements … while some therapies may hold promise and warrant further study, substantial needs exist for continuing improvements
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effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/should-subclinical-hypothroidism-be-treated
November 01, 2017 - Desired Health Improvements: If you question focuses on: … Identification of a particular disease or condition, what improvements in identification or diagnosis … Treatment of a particular disease or condition, what improvements in patient symptoms or problems would
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effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/more-information-is-needed-on-the-long-term-effects-of-antipsychotic-therapy-in-older-adults-please-consider-new-research-in-the-benefits-and-harms-of-treating-patients-with-atypical-antipsychotics
November 01, 2017 - Desired Health Improvements: If you question focuses on: … Identification of a particular disease or condition, what improvements in identification or diagnosis … Treatment of a particular disease or condition, what improvements in patient symptoms or problems would
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effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/what-is-the-most-effective-therapy-for-a-depressed-patient-who-has-not-responded-to-an-ssri
November 01, 2017 - Desired Health Improvements: If you question focuses on: … Identification of a particular disease or condition, what improvements in identification or diagnosis … Treatment of a particular disease or condition, what improvements in patient symptoms or problems would
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effectivehealthcare-admin.ahrq.gov/sites/default/files/nonopioid-chronic-pain-summary.pdf
April 01, 2020 - The
antidepressant duloxetine resulted in small
improvements in pain, function, and quality of life … In patients with fibromyalgia, RCTs (n=24)
show small short-term and intermediate-term
improvements … Anticonvulsants
pregabalin and gabapentin show short-term
improvements in pain and function but not … Acetaminophen did not show
improvements in pain or function, across all
doses (SOE: Low). … In patients with inflammatory
arthritis (k=30 RCTs), NSAIDs resulted in
small improvements in pain
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/autism-adolescents_executive.pdf
August 01, 2012 - There is also evidence to suggest that improvements
in symptoms and improvements in problem behaviors … One longer term
case series reported improvements in general symptom
severity and compulsive behavior … • Some improvements in emotion recognition in treated participants; no differences in
measures of … • Improvements in aggression, irritability/agitation, repetitive behavior, sensory motor
behaviors … A crossover study of the opioid receptor antagonist
naltrexone found no significant improvements in
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effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/my-nomination-is-about-comparing-outcomes-of-different-glaucoma-treatments-particularly-canaloplasty-to-trabeculectomy-and-to-medical-therapy-alone
November 01, 2017 - Desired Health Improvements: If you question focuses on: … Identification of a particular disease or condition, what improvements in identification or diagnosis … Treatment of a particular disease or condition, what improvements in patient symptoms or problems would