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Showing results for "improved".

  1. effectivehealthcare.ahrq.gov/sites/default/files/related_files/autism-adolescents_surveillance.pdf
    July 01, 2014 - Most reported improved core symptoms but each study had different approach. … Most reported improved core symptoms but each study had different approach. … Medical Interventions One retrospective case-series6 reported improved core symptoms with oxcarbazepine … One RCT9 reported improved core symptoms with fluoxetine treatment. … Behavioral Interventions One nonrandomized study4 reported improved parental and sibling outcomes
  2. effectivehealthcare.ahrq.gov/sites/default/files/related_files/juvenile-arthritis-dmards_surveillance.pdf
    March 14, 2013 - Health status improved inconsistently with treatment with DMARDs. … One expert expressed that they show that both tocilizumab and canakinumab caused improved CHAQ in … Also all JIA core set response variables improved significantly over 27 months of etanercept treatment … All ab regimens led to improved MRI, HAQ and SF-36 scores, with 10mg/kg showing the greatest improvements … Health status improved inconsistently with treatment with DMARDs.
  3. effectivehealthcare.ahrq.gov/sites/default/files/pdf/juvenile-arthritis-dmards_surveillance.pdf
    March 14, 2013 - Health status improved inconsistently with treatment with DMARDs. … One expert expressed that they show that both tocilizumab and canakinumab caused improved CHAQ in … Also all JIA core set response variables improved significantly over 27 months of etanercept treatment … All ab regimens led to improved MRI, HAQ and SF-36 scores, with 10mg/kg showing the greatest improvements … Health status improved inconsistently with treatment with DMARDs.
  4. Ced-Appendix-3 (xls file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/ced-appendix-3.xlsx
    June 24, 2022 - Duke-M Protocol The validity of RWE from retrospective observational studies is improved with prespecification … Duke-M Reproducibility The validity of RWE from retrospective observational studies is improved with … NAM2017 Improved communication from leadership within the biopharmaceutical industry and regulatory sectors … Drug development processes could be improved by applying lessons learned and best practices from those … NAM2017 Need for improved transparency -sharing of study methods and outcomes.
  5. Diabetes Mellitus (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/diabetes-horizon-scan-high-impact-1512.pdf
    December 01, 2015 - Most were observed early in the course of treatment and improved over time,” the company stated.11 … Patient-reported weight-related quality of life improved from baseline on the Impact of Weight on Quality … with T2DM and BMIs of 30–35 kg/m2.50 Investigators found that at 6 months, the surgery group had improved … expert noted, “Specialists caring for patients with T1DM are interested in inhaled insulin as an improvedImproved diabetic macular edema outcomes with Iluvien therapy is likely to decrease the incidence of
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/insomnia_disposition-comments.pdf
    December 30, 2015 - Introduction Page 4 Table 2 in both main document and executive summary The definition of CBT can be improved … patient-centered outcomes such as mood and well-being, quality of life, and productivity through improved … mood; secondary were considered ‘secondary’ to improved sleep (not direct consequences of the treatment … For instance, it is not entirely clear how this review can conclude that doxepin improved global outcomes … Should the next to last sentence read ‘Low strength evidence shows that zolpidem improved sleep onset
  7. effectivehealthcare.ahrq.gov/sites/default/files/related_files/sleep-apnea_surveillance.pdf
    April 01, 2012 - Two reported reductions in sleepiness and one improved quality of life. … The results were inconsistent across studies as to which outcomes were improved with surgery compared … The strength of evidence is moderate that a higher ESS score is also associated with improved compliance … The quality of life improved only in the CPAP group (p=0.01) Sharma, 201121; India Crossover RCT … The results were inconsistent across studies as to which outcomes were improved with surgery
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/treatment-outcomes-diabetes-rapid-research.pdf
    November 01, 2024 - of dental treatment over two months and found that continued dental treatment was associated with improved … Two of the URs25,26 of high quality concluded that NSPT is associated with improved glycemic control … Improved glycemic control (HbA1c): • 3 months: −0.49% (95% CI [− 0.63, − 0.35], p < 0.001), (18 studies … Improved glycemic control: • HbA1c: -0.32%(95%CI: [-0.50, -0.15], p<0.001) • FPG: -11.59 mg/dl; 95% … Nonsurgical Periodontal Treatment Improved the Type 2 Diabetes Mellitus Status in Smokers: A Randomized
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/diabetic-neuropathy-disposition-170707.pdf
    March 24, 2017 - No treatments improved quality of life (low SOE). … inhibitors are more effective than anticonvulsants THIS IS NOT REALLY THE CASE however, no treatments improved … spinal stimulation, the conclusion should be expanded to something like, "compared to placebo pain is improved … but there is not adequate data on improved function.
  10. effectivehealthcare.ahrq.gov/sites/default/files/diabetic-neuropathy-disposition-170707.pdf
    March 24, 2017 - No treatments improved quality of life (low SOE). … inhibitors are more effective than anticonvulsants THIS IS NOT REALLY THE CASE however, no treatments improved … spinal stimulation, the conclusion should be expanded to something like, "compared to placebo pain is improved … but there is not adequate data on improved function.
  11. effectivehealthcare.ahrq.gov/sites/default/files/pdf/procalcitonin_research-protocol.pdf
    September 08, 2011 - Improved/ earlier diagnosis of local or systemic infection Improved selection, exclusion, or … timing of antibiotic therapy Improved intermediate out- comes (antibiotic exposure, duration … of antibiotic therapy, length of stay, response to therapy) Improved morbidity, function, quality
  12. #14 SUBSTANCE ABUSE (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/14_substance_abuse_potential_high_impact_2012-12-11.pdf
    January 01, 2012 - They viewed this intervention as having some ability to meet the need for improved patient adherence … results from the phase III confirmatory study suggested that treatment with the implant significantly improved … buprenorphine implant. 25-31 Experts generally agreed that opioid-dependence therapies that offer improved … with 7 currently available therapies’ initial costs, but some stated that if adherence is improved
  13. effectivehealthcare.ahrq.gov/sites/default/files/dementia-horizon-scan-high-impact-1412.pdf
    February 01, 2015 - Intranasal insulin treatment improved patients’ cognitive performance (p<0.05; measured by delayed … cognitive improvements when administered 20 IU intranasal insulin, but only male patients’ cognition improved … the same research group reported that patients with AD or MCI who carried the ApoE-ε4 allele had improved … cognitive scores declined with the same treatment; however, all patients’ working memory performance improved
  14. effectivehealthcare.ahrq.gov/sites/default/files/developmental-delays-horizon-scan-high-impact-1406.pdf
    June 01, 2014 - research supports a hypothesis that ES-3 earlier diagnosis and intervention may result in improved … studies have reported that intranasal oxytocin increases systemic oxytocin levels that may be linked to improved … 3 in high-functioning adult males with ASDs (n=40) reported that a single 24 IU oxytocin dose improved … enrolling adolescent patients with ASDs (n=16), two different oxytocin dosages were associated with improved
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/Evidence%20Summary_0_0.pdf
    April 01, 2020 - studies of participants with a wide range of depressive disorders (MDD, PDD, or DD NOS) suggests improved … benefit Adolescents with MDD Response Risk difference (CGI-I of 1 or 2 indicating very much improved … or improved): 362/1,000; 95% CI, 239 more cases to 485 more cases 1 RCT (n=219)23 Imprecision … or improved): 362/1,000; 95% CI, 239 more cases to 485 more cases 1 RCT (n=219)23 Imprecision … Combination pharmacotherapy may not be associated with improved depressive symptoms when compared with
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c-treatment-adherence_disposition-comments.pdf
    December 20, 2012 - Section Comment Response FDA Executive Summary On page ES-1, An addition to this introduction may be improved … with the inclusion of a notation that outcome of treatment improved with the development/usage of pegylated … Most notably and relevant are the improvement in adherence issues that were associated with the improved … Three studies suggested adherence was improved, whereas the other two showed lower adherence level … Given the inconsistency of the findings, the lack of evidence showing improved clinical outcomes,
  17. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/sleep-apnea_executive.pdf
    July 01, 2011 - analytic framework depicts the chain of logic that evidence must support to link the interventions to improved … The results were inconsistent across studies as to which outcomes were improved with surgery compared … The strength of evidence is moderate that a higher ESS score is also associated with improved compliance … The strength of evidence is moderate that higher ESS is also associated with improved compliance. … None improved compliance.
  18. effectivehealthcare.ahrq.gov/sites/default/files/13_pulmonary_potential_high_impact_2012-12-11.pdf
    January 01, 2012 - Cystic Fibrosis in Patients with G551D-CFTR Mutation  Key Facts: Current therapies for CF have improved … Cystic Fibrosis in Patients with G551D-CFTR Mutation Current therapies for cystic fibrosis (CF) have improved … coverage, patient copayments, real-world clinical efficacy, and offsets of other health care costs from improved
  19. effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-antigen-3-gene_research.pdf
    April 01, 2013 - including diagnostic accuracy (clinical validity) for prostate cancer, intermediate outcomes (e.g., improved … including diagnostic accuracy (clinical validity) for prostate cancer, intermediate outcomes (e.g., improved … The CER analyses revealed that PCA3 had improved diagnostic accuracy compared with tPSA in identifying … including diagnostic accuracy (clinical validity) for prostate cancer, intermediate outcomes (e.g., improved … With regard to the intermediate outcome of improved decisionmaking, PCA3 does have the potential to
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/binge-eating_executive.pdf
    December 01, 2015 - Ultimately, the information produced in this review is intended to contribute to improved care for patients … Even though patients improved, many did not achieve abstinence with antidepressants; 41 percent of … Lisdexamfetamine improved binge-eating outcomes. … We have two recommendations for improved designs. … Change in attachment insecurity is related to improved outcomes 1-year post group therapy in women

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